Mus musculus (house mouse): 11687
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Entry
11687 CDS
T01002
Symbol
Alox15, 12-LO, 12/15-LO, 15-LOX, Alox12l, L-12LO
Name
(RefSeq) arachidonate 15-lipoxygenase
KO
K00460
arachidonate 15-lipoxygenase [EC:
1.13.11.33
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00590
Arachidonic acid metabolism
mmu00591
Linoleic acid metabolism
mmu01100
Metabolic pathways
mmu04148
Efferocytosis
mmu04216
Ferroptosis
mmu04217
Necroptosis
mmu04726
Serotonergic synapse
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09103 Lipid metabolism
00590 Arachidonic acid metabolism
11687 (Alox15)
00591 Linoleic acid metabolism
11687 (Alox15)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
11687 (Alox15)
09143 Cell growth and death
04216 Ferroptosis
11687 (Alox15)
04217 Necroptosis
11687 (Alox15)
09150 Organismal Systems
09156 Nervous system
04726 Serotonergic synapse
11687 (Alox15)
Enzymes [BR:
mmu01000
]
1. Oxidoreductases
1.13 Acting on single donors with incorporation of molecular oxygen (oxygenases)
1.13.11 With incorporation of two atoms of oxygen
1.13.11.33 arachidonate 15-lipoxygenase
11687 (Alox15)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Lipoxygenase
PLAT
Nlig-Ia
Motif
Other DBs
NCBI-GeneID:
11687
NCBI-ProteinID:
NP_033790
MGI:
87997
Ensembl:
ENSMUSG00000018924
UniProt:
P39654
A2CF88
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All DBs
Position
11:complement(70234973..70279465)
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AA seq
663 aa
AA seq
DB search
MGVYRIRVSTGDSVYAGSNNEVYLWLIGQHGEASLGKLFRPCRNSEAEFKVDVSEYLGPL
LFVRVQKWHYLKEDAWFCNWISVKGPGDQGSEYTFPCYRWVQGTSILNLPEGTGCTVVED
SQGLFRNHREEELEERRSLYRWGNWKDGTILNVAATSISDLPVDQRFREDKRLEFEASQV
LGTMDTVINFPKNTVTCWKSLDDFNYVFKSGHTKMAERVRNSWKEDAFFGYQFLNGANPM
VLKRSTCLPARLVFPPGMEKLQAQLDEELKKGTLFEADFFLLDGIKANVILCSQQYLAAP
LVMLKLQPDGQLLPIAIQLELPKTGSTPPPIFTPLDPPMDWLLAKCWVRSSDLQLHELQA
HLLRGHLVAEVFAVATMRCLPSVHPVFKLLVPHLLYTMEINVRARSDLISERGFFDKVMS
TGGGGHLDLLKQAGAFLTYSSLCPPDDLAERGLLDIDTCFYAKDALQLWQVMNRYVVGMF
DLYYKTDQAVQDDYELQSWCQEITEIGLQGAQDRGFPTSLQSRAQACHFITMCIFTCTAQ
HSSIHLGQLDWFYWVPNAPCTMRLPPPKTKDATMEKLMATLPNPNQSTLQINVVWLLGRR
QAVMVPLGQHSEEHFPNPEAKAVLKKFREELAALDKEIEIRNKSLDIPYEYLRPSLVENS
VAI
NT seq
1992 nt
NT seq
+upstream
nt +downstream
nt
atgggtgtctaccgcatccgcgtctccaccggggactccgtgtacgcgggctccaacaac
gaggtctacctgtggttgatcggacagcatggggaggcatctctcgggaagctgttccga
ccctgtcggaactcggaggcagaattcaaggtggatgtgtcagaataccttgggccactg
ctgtttgtgagagtgcagaaatggcattatctcaaagaggacgcctggttctgcaactgg
atttctgtgaagggccccggagaccagggatcggagtacacgttcccctgttaccgatgg
gttcagggcaccagcatcctgaacctccctgagggcactggctgcaccgtggttgaagac
tctcaaggcctgttcaggaaccacagggaggaggaactggaagaaaggaggagtctgtac
aggtggggcaactggaaggatggcacaatcctgaacgtggcggcgaccagtatctctgac
ctccctgtagaccagcgatttcgagaggacaaaagacttgaatttgaagcttcacaggtt
ctggggacaatggacaccgttattaacttccctaaaaacactgtgacctgctggaaaagc
ctagatgacttcaactatgttttcaagagtggccacaccaagatggctgagcgggttcga
aactcctggaaagaggatgctttctttgggtaccagtttctcaatggtgctaaccccatg
gtgctgaagcggtctacttgtctccctgcccgcctggtattccctccggggatggagaag
ctacaggcccagctggatgaggagctcaagaaaggcactctgtttgaagcggatttcttc
cttctggatgggatcaaggccaatgtcatcctttgtagtcagcagtacctggctgccccc
ctcgtcatgctgaagctgcagcccgatgggcaactcttgcctatagccatccagctcgaa
ctgcccaaaactgggtctaccccaccgccgattttcacgcccttggatcccccaatggac
tggctcctggccaaatgctgggtccgaagctcagacttacagcttcatgagctacaggct
catcttctgaggggacacttggtggctgaggtctttgctgtggccaccatgaggtgcctg
ccttccgtgcaccctgtttttaagcttctagttcctcacctactctacaccatggaaatc
aatgtccgggccaggagcgacctgatctcagagagaggcttttttgacaaggtgatgagc
acaggtggaggaggccacctggatcttctcaagcaagctggagccttcctgacctacagc
tcattgtgtccccctgatgacttggctgagcgaggactcctggatattgacacttgcttc
tatgctaaagatgccctgcagctctggcaagtcatgaatcggtacgtggtgggaatgttc
gatctctactacaagaccgaccaagctgttcaggatgactatgaactgcagagctggtgt
caagagatcactgagattgggttgcaaggtgcccaggacagaggcttccccacctccctc
cagtcccgggctcaggcttgccacttcatcaccatgtgcatcttcacatgcactgcgcag
cactcttccatccatcttggccagctggattggttctactgggttcctaatgcaccctgc
accatgcggctgccaccacctaaaaccaaggacgcgacgatggagaagctgatggcgacg
ctgcccaatcctaatcagtctactctccagataaatgtcgtttggctcctgggcagacgc
caggctgttatggtgcccctgggccagcattcagaggaacacttcccaaaccctgaggcc
aaagctgtgctgaagaagttcagagaggagctggctgccttggataaggaaattgagatt
cgtaacaagagcttggacataccttatgagtacctgcggcccagcctggtagaaaacagc
gtggccatatga
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