Mus musculus (house mouse): 11772
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Entry
11772 CDS
T01002
Symbol
Ap2a2, 2410074K14Rik, Adtab, L25
Name
(RefSeq) adaptor-related protein complex 2, alpha 2 subunit
KO
K11824
AP-2 complex subunit alpha
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04144
Endocytosis
mmu04721
Synaptic vesicle cycle
mmu04961
Endocrine and other factor-regulated calcium reabsorption
mmu05016
Huntington disease
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
11772 (Ap2a2)
09150 Organismal Systems
09155 Excretory system
04961 Endocrine and other factor-regulated calcium reabsorption
11772 (Ap2a2)
09156 Nervous system
04721 Synaptic vesicle cycle
11772 (Ap2a2)
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
11772 (Ap2a2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
11772 (Ap2a2)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
11772 (Ap2a2)
Membrane trafficking [BR:
mmu04131
]
Endocytosis
Clathrin-mediated endocytosis
AP-2 complex
11772 (Ap2a2)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
11772 (Ap2a2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Adaptin_N
Alpha_adaptin_C
Alpha_adaptinC2
Cnd1
HEAT_2
HEAT_EF3_N
RIX1
TOR1L1_N
PDS5
UTP20_N
Motif
Other DBs
NCBI-GeneID:
11772
NCBI-ProteinID:
NP_031485
MGI:
101920
Ensembl:
ENSMUSG00000002957
UniProt:
P17427
Q6PEE6
Q69ZW4
Structure
PDB
PDBj
LinkDB
All DBs
Position
7:141142093..141212924
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AA seq
938 aa
AA seq
DB search
MPAVSKGDGMRGLAVFISDIRNCKSKEAEIKRINKELANIRSKFKGDKALDGYSKKKYVC
KLLFIFLLGHDIDFGHMEAVNLLSSNRYTEKQIGYLFISVLVNSNSELIRLINNAIKNDL
ASRNPTFMGLALHCIANVGSREMAEAFAGEIPKILVAGDTMDSVKQSAALCLLRLYRTSP
DLVPMGDWTSRVVHLLNDQHLGVVTAATSLITTLAQKNPEEFKTSVSLAVSRLSRIVTSA
STDLQDYTYYFVPAPWLSVKLLRLLQCYPPPDPAVRGRLTECLETILNKAQEPPKSKKVQ
HSNAKNAVLFEAISLIIHHDSEPNLLVRACNQLGQFLQHRETNLRYLALESMCTLASSEF
SHEAVKTHIETVINALKTERDVSVRQRAVDLLYAMCDRSNAQQIVAEMLSYLETADYSIR
EEIVLKVAILAEKYAVDYTWYVDTILNLIRIAGDYVSEEVWYRVIQIVINRDDVQGYAAK
TVFEALQAPACHENLVKVGGYILGEFGNLIAGDPRSSPLIQFNLLHSKFHLCSVPTRALL
LSTYIKFVNLFPEVKATIQDVLRSDSQLKNADVELQQRAVEYLRLSTVASTDILATVLEE
MPPFPERESSILAKLKKKKGPSTVTDLEETKRERSIDVNGGPEPVPASTSAASTPSPSAD
LLGLGAVPPAPTGPPPSSGGGLLVDVFSDSASAVAPLAPGSEDNFARFVCKNNGVLFENQ
LLQIGLKSEFRQNLGRMFIFYGNKTSTQFLNFTPTLICADDLQTNLNLQTKPVDPTVDGG
AQVQQVVNIECISDFTEAPVLNIQFRYGGTFQNVSVKLPITLNKFFQPTEMASQDFFQRW
KQLSNPQQEVQNIFKAKHPMDTEITKAKIIGFGSALLEEVDPNPANFVGAGIIHTKTTQI
GCLLRLEPNLQAQMYRLTLRTSKDTVSQRLCELLSEQF
NT seq
2817 nt
NT seq
+upstream
nt +downstream
nt
atgccggccgtatccaagggggacgggatgcgaggcctagcggtcttcatctccgacatc
cgcaactgtaaaagtaaagaagctgaaataaagagaataaacaaagaactggcaaatatt
agatccaaatttaaaggtgacaaggctcttgatggctacagtaaaaagaagtatgtctgc
aaattgctcttcatctttctccttggtcatgacattgactttggacacatggaagctgtg
aatcttctgagctcaaacagatacacggaaaagcagattggctaccttttcatctctgta
ttggtgaactcgaatagtgaactgatccggttgattaacaatgccatcaagaatgacctg
gccagccgcaatcctacgtttatgggtctcgccctgcactgcattgccaatgtgggtagc
cgtgagatggcggaggccttcgccggagagatccccaagatcctcgtggcaggagatacc
atggatagtgtgaagcagagcgcagccctgtgcttgttacgcctgtacaggacatcacct
gacctagttcccatgggcgactggacatctcgtgtggtacacctcctcaatgaccagcac
ttgggggtagtgactgcagcgactagcctcatcaccaccctggcccagaagaaccctgag
gagttcaagacctctgtctcgctagctgtctcgcgactgagcaggattgtgacgtctgca
tcaacagatcttcaggattatacttactactttgtcccggctccttggctgtcagtcaag
cttctgagactgctgcagtgctacccacccccagaccctgcggtgcgtggccgcctgact
gagtgcttggagaccatcctgaacaaggcccaggagccacccaagtccaagaaggtccag
cattcaaatgccaagaacgctgtgctgtttgaggccatcagcctgatcatccaccatgac
agtgagccaaacttgctcgtccgcgcctgcaaccagctgggccagttcctgcagcaccgg
gagacgaacctacgctacctggctctggagagcatgtgcacgctggccagctctgagttc
tcccacgaggccgtcaagacccacattgagacggtcatcaatgccttgaagacggaaaga
gacgtgagtgtgaggcagcgggcagtggacctgctctacgccatgtgtgaccggagcaac
gcccagcagattgtggctgagatgctgagctacctagaaacggctgactactccatccga
gaggaaattgtgctgaaggtggccatcctggctgagaagtatgcagtggactacacttgg
tatgtggacaccatcctcaacctcatccgcatcgcgggcgactatgtgagcgaggaggtg
tggtaccgcgtcatccagattgtcatcaatcgcgatgatgtgcagggctatgctgccaag
acggtatttgaggcattgcaggcgccagcatgtcatgagaacttggtcaaagtgggcggc
tacatcctgggggagtttggaaacttgatagctggggacccacgatccagccctctgatc
cagttcaacctgctccactccaagttccacttgtgcagcgtccccactcgggcactcctg
ctgtccacctacatcaagttcgtgaacctctttccagaggtaaaagctaccattcaggac
gtgctgcgcagtgacagccagctgaagaatgccgacgtggagctgcagcagcgggctgtg
gagtacctgcgactgagcactgtcgccagcactgacatcctggcaactgtcctggaggaa
atgccacccttccctgagcgtgagtcctccatcttggccaagctgaagaagaagaagggc
ccaagcacagtgactgacctggaggagaccaagcgggagcgaagcatcgatgtgaatggg
ggccctgaacccgttccagccagcaccagtgctgcgtccacaccttctccgtcagcagac
ctgctgggtctgggggccgtgccccctgctcccacggggccccctccctcctctggcggc
gggctgctggtggacgtgttctcagactcagcttctgcagtcgcacctcttgcacccggc
tctgaagacaactttgccaggtttgtttgtaaaaataatggtgtattgttcgaaaaccag
ctgcttcaaattggacttaagtcagaatttcggcagaatttaggccgaatgttcatattt
tatggtaacaagacctccacgcagttcctaaacttcactccaacactaatctgtgctgac
gaccttcaaactaatctgaacctgcagactaagcccgtggacccaactgtggatgggggc
gcacaggtgcaacaagtggtcaacattgagtgtatatctgatttcacagaggcacctgtc
ctcaacatccagttcaggtatggtgggaccttccagaatgtgtctgttaagcttcccatc
actctcaacaaatttttccagcccacagaaatggcttctcaggatttctttcaacgttgg
aagcagttgagcaatccacagcaagaagtgcagaatatcttcaaagcaaagcatccgatg
gacacagagatcactaaggcaaagattattggatttggttctgcgctcctggaagaagtt
gacccgaatcctgcaaatttcgtgggtgctggcataatacacaccaaaaccacccagatt
ggctgcttgttgcgcctggagccaaacctgcaagctcagatgtatagactcaccttgcgt
accagcaaagacaccgtctctcagagactatgtgaattgctgtcggaacagttctag
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