Mus musculus (house mouse): 11789
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Entry
11789 CDS
T01002
Symbol
Apc, CC1, Min, mAPC
Name
(RefSeq) APC, WNT signaling pathway regulator
KO
K02085
adenomatosis polyposis coli protein
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04310
Wnt signaling pathway
mmu04390
Hippo signaling pathway
mmu04550
Signaling pathways regulating pluripotency of stem cells
mmu04810
Regulation of actin cytoskeleton
mmu04934
Cushing syndrome
mmu05010
Alzheimer disease
mmu05022
Pathways of neurodegeneration - multiple diseases
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05206
MicroRNAs in cancer
mmu05210
Colorectal cancer
mmu05213
Endometrial cancer
mmu05217
Basal cell carcinoma
mmu05224
Breast cancer
mmu05225
Hepatocellular carcinoma
mmu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
11789 (Apc)
04390 Hippo signaling pathway
11789 (Apc)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04550 Signaling pathways regulating pluripotency of stem cells
11789 (Apc)
09142 Cell motility
04810 Regulation of actin cytoskeleton
11789 (Apc)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
11789 (Apc)
05206 MicroRNAs in cancer
11789 (Apc)
09162 Cancer: specific types
05210 Colorectal cancer
11789 (Apc)
05225 Hepatocellular carcinoma
11789 (Apc)
05226 Gastric cancer
11789 (Apc)
05217 Basal cell carcinoma
11789 (Apc)
05213 Endometrial cancer
11789 (Apc)
05224 Breast cancer
11789 (Apc)
09172 Infectious disease: viral
05165 Human papillomavirus infection
11789 (Apc)
09164 Neurodegenerative disease
05010 Alzheimer disease
11789 (Apc)
05022 Pathways of neurodegeneration - multiple diseases
11789 (Apc)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
11789 (Apc)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
mmu01009
]
11789 (Apc)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmu03036
]
11789 (Apc)
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
mmu04812
]
11789 (Apc)
Protein phosphatases and associated proteins [BR:
mmu01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
11789 (Apc)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Centrosome formation proteins
Other centrosome associated proteins
11789 (Apc)
Cytoskeleton proteins [BR:
mmu04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
EB / APC
11789 (Apc)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Arm_APC_u3
APC_basic
EB1_binding
APC_r
APC_u5
APC_rep
APC_u14
APC_u15
APC_u9
SAMP
Arm
APC_u13
APC_15aa
Suppressor_APC
ARM_ARMC5
ZER1-like_2nd
Sec7-like_HUS
Motif
Other DBs
NCBI-GeneID:
11789
NCBI-ProteinID:
NP_001347908
MGI:
88039
Ensembl:
ENSMUSG00000005871
LinkDB
All DBs
Position
18:34353350..34455243
Genome browser
AA seq
2783 aa
AA seq
DB search
MTSGQIDLLERLKEFNLDSNFPGVKLRSKMSLRSYGSREGSVSSRSGECSPVPMGSFPRR
TFVNGSRESTGYLEELEKERSLLLADLDKEEKEKDWYYAQLQNLTKRIDSLPLTENFSLQ
TDMTRRQLEYEARQIRAAMEEQLGTCQDMEKRAQRRIARIQQIEKDILRVRQLLQSQAAE
AERSSQSRHDAASHEAGRQHEGHGVAESNTAASSSGQSPATRVDHETASVLSSSGTHSAP
RRLTSHLGTKVEMVYSLLSMLGTHDKDDMSRTLLAMSSSQDSCISMRQSGCLPLLIQLLH
GNDKDSVLLGNSRGSKEARARASAALHNIIHSQPDDKRGRREIRVLHLLEQIRAYCETCW
EWQEAHEQGMDQDKNPMPAPVEHQICPAVCVLMKLSFDEEHRHAMNELGGLQAIAELLQV
DCEMYGLTNDHYSVTLRRYAGMALTNLTFGDVANKATLCSMKGCMRALVAQLKSESEDLQ
QVIASVLRNLSWRADVNSKKTLREVGSVKALMECALEVKKESTLKSVLSALWNLSAHCTE
NKADICAVDGALAFLVGTLTYRSQTNTLAIIESGGGILRNVSSLIATNEDHRQILRENNC
LQTLLQHLKSHSLTIVSNACGTLWNLSARNPKDQEALWDMGAVSMLKNLIHSKHKMIAMG
SAAALRNLMANRPAKYKDANIMSPGSSLPSLHVRKQKALEAELDAQHLSETFDNIDNLSP
KASHRSKQRHKQNLYGDYAFDANRHDDSRSDNFNTGNMTVLSPYLNTTVLPSSSSSRGSL
DSSRSEKDRSLERERGIGLSAYHPTTENAGTSSKRGLQITTTAAQIAKVMEEVSAIHTSQ
DDRSSASTTEFHCVADDRSAARRSSASHTHSNTYNFTKSENSNRTCSMPYAKVEYKRSSN
DSLNSVTSSDGYGKRGQMKPSVESYSEDDESKFCSYGQYPADLAHKIHSANHMDDNDGEL
DTPINYSLKYSDEQLNSGRQSPSQNERWARPKHVIEDEIKQNEQRQARSQNTSYPVYSEN
TDDKHLKFQPHFGQQECVSPYRSRGTSGSETNRMGSSHAINQNVNQSLCQEDDYEDDKPT
NYSERYSEEEQHEEEEERPTNYSIKYNEEKHHVDQPIDYSLKYATDISSSQKPSFSFSKN
SSAQSTKPEHLSPSSENTAVPPSNAKRQNQLRPSSAQRNGQTQKGTTCKVPSINQETIQT
YCVEDTPICFSRCSSLSSLSSADDEIGCDQTTQEADSANTLQTAEVKENDVTRSAEDPAT
EVPAVSQNARAKPSRLQASGLSSESTRHNKAVEFSSGAKSPSKSGAQTPKSPPEHYVQET
PLVFSRCTSVSSLDSFESRSIASSVQSEPCSGMVSGIISPSDLPDSPGQTMPPSRSKTPP
PPPQTVQAKREVPKSKVPAAEKRESGPKQTAVNAAVQRVQVLPDVDTLLHFATESTPDGF
SCSSSLSALSLDEPFIQKDVELRIMPPVQENDNGNETESEQPEESNENQDKEVEKPDSEK
DLLDDSDDDDIEILEECIISAMPTKSSRKAKKLAQTASKLPPPVARKPSQLPVYKLLPAQ
NRLQAQKHVSFTPGDDVPRVYCVEGTPINFSTATSLSDLTIESPPNELATGDGVRAGIQS
GEFEKRDTIPTEGRSTDDAQRGKISSIVTPDLDDNKAEEGDILAECINSAMPKGKSHKPF
RVKKIMDQVQQASSTSSGANKNQVDTKKKKPTSPVKPMPQNTEYRTRVRKNTDSKVNVNT
EETFSDNKDSKKPSLQTNAKAFNEKLPNNEDRVRGSFALDSPHHYTPIEGTPYCFSRNDS
LSSLDFDDDDVDLSREKAELRKGKESKDSEAKVTCRPEPNSSQQAASKSQASIKHPANRA
QSKPVLQKQPTFPQSSKDGPDRGAATDEKLQNFAIENTPVCFSRNSSLSSLSDIDQENNN
NKESEPIKEAEPANSQGEPSKPQASGYAPKSFHVEDTPVCFSRNSSLSSLSIDSEDDLLQ
ECISSAMPKKKRPSRLKSESEKQSPRKVGGILAEDLTLDLKDLQRPDSEHAFSPDSENFD
WKAIQEGANSIVSSLHQAAAAAACLSRQASSDSDSILSLKSGISLGSPFHLTPDQEEKPF
TSNKGPRILKPGEKSTLEAKKIESENKGIKGGKKVYKSLITGKIRSNSEISSQMKQPLPT
NMPSISRGRTMIHIPGLRNSSSSTSPVSKKGPPLKTPASKSPSEGPGATTSPRGTKPAGK
SELSPITRQTSQISGSNKGSSRSGSRDSTPSRPTQQPLSRPMQSPGRNSISPGRNGISPP
NKLSQLPRTSSPSTASTKSSGSGKMSYTSPGRQLSQQNLTKQASLSKNASSIPRSESASK
GLNQMSNGNGSNKKVELSRMSSTKSSGSESDRSERPALVRQSTFIKEAPSPTLRRKLEES
ASFESLSPSSRPDSPTRSQAQTPVLSPSLPDMSLSTHPSVQAGGWRKLPPNLSPTIEYND
GRPTKRHDIARSHSESPSRLPINRAGTWKREHSKHSSSLPRVSTWRRTGSSSSILSASSE
SSEKAKSEDERHVSSMPAPRQMKENQVPTKGTWRKIKESDISPTGMASQSASSGAASGAE
SKPLIYQMAPPVSKTEDVWVRIEDCPINNPRSGRSPTGNTPPVIDSVSEKGSSSIKDSKD
THGKQSVGSGSPVQTVGLETRLNSFVQVEAPEQKGTEAKPGQSNPVSIAETAETCIAERT
PFSSSSSSKHSSPSGTVAARVTPFNYNPSPRKSSADSTSARPSQIPTPVSTNTKKRDSKT
DSTESSGAQSPKRHSGSYLVTSV
NT seq
8352 nt
NT seq
+upstream
nt +downstream
nt
atgacttctggacagattgacttactagagcgtcttaaagaatttaacttagatagtaat
ttccccggagtgaaactacgctcaaaaatgtcccttcgctcctacggaagtcgggaagga
tctgtatccagccgttcaggagaatgcagtcctgtccccatggggtcattcccaagaaga
acatttgtaaatggaagcagagagagtactgggtatctagaagagcttgaaaaagaaaga
tcattactccttgctgatcttgacaaagaagagaaggaaaaggactggtattatgctcaa
cttcagaacctcacaaaaagaatagatagcctgcctttaactgaaaatttttccttacag
acagacatgacaagacggcagctggagtatgaagcaaggcagatcagggctgcaatggag
gagcagcttggcacctgccaggacatggagaagcgtgcacagcgaagaatagccaggatc
cagcaaatagaaaaggacatactgcgcgtgcgccagcttttacagtcccaggcggcggaa
gcggagaggtcatctcagagcaggcatgatgctgcctcccatgaagctggccggcagcac
gaaggccacggagtggcagaaagcaacaccgcagcctccagtagtggtcagagtccagct
acacgtgtggatcacgaaacagccagtgttttgagttctagcggcacgcactctgctcct
cgaaggttgacaagtcatctggggacaaaggtggaaatggtgtattccttgttgtcaatg
cttggtactcatgataaggacgatatgtcacgaactttgctagctatgtccagctcccaa
gacagctgtatatccatgcggcagtctggatgtcttcctctcctcatccagcttttacat
ggcaatgacaaagactctgtattgttgggaaattcccggggcagtaaagaggctcgggcc
agggccagtgcagcactccacaacatcattcactcacagcctgatgacaagagaggcagg
cgtgaaatccgagtccttcatcttttggaacagatacgagcttactgtgaaacctgttgg
gagtggcaggaagcccacgaacaaggcatggaccaggacaaaaacccaatgccagctcct
gttgagcatcagatctgtcctgctgtgtgtgttctaatgaagctttcatttgatgaagag
cataggcatgcaatgaatgaacttgggggactgcaggccattgcagagttattgcaggtg
gactgtgagatgtatgggcttactaatgaccactacagtgttactttaagacggtatgct
ggaatggctttgacaaacttgacctttggagatgttgccaacaaggctacgctgtgttct
atgaaaggctgcatgagagcacttgtggcccagttaaaatctgagagtgaagacttacag
caggttattgcaagtgttttgaggaatttgtcttggcgagcagatgtaaatagcaaaaag
acgttgagagaagttggaagtgtgaaagcattgatggaatgtgctttggaagttaaaaag
gaatcaaccctcaaaagcgttttgagtgccttatggaacctgtctgcacactgcactgag
aataaggctgacatctgtgctgtggatggagcactggcatttctggttggcaccctcact
taccggagccagacaaatactttagccattattgaaagtggaggtgggatattacggaat
gtgtccagcttgatagctacaaacgaagaccacaggcaaatcctaagagagaacaattgc
ctacaaactttattacagcacttgaaatctcacagcttgacaatagtcagtaatgcatgt
ggaactttgtggaatctctcagcaagaaatcctaaagaccaggaagccttgtgggacatg
ggggcagtgagcatgctcaagaacctcattcattccaagcacaaaatgattgccatggga
agtgcagcagctttaaggaatctcatggcaaacagacctgcaaagtataaggatgccaat
atcatgtctcccggctcaagtctgccatcccttcacgttaggaaacagaaagctctagaa
gctgagctagatgctcagcatttatcagaaaccttcgacaacattgacaacctaagtccc
aaggcctctcaccggagtaagcagagacacaagcagaatctttatggtgactatgctttt
gacgccaatcgacatgatgatagtaggtcagacaatttcaatactggaaacatgactgtt
ctttcaccatatttaaatactacggtattgcccagctcttcttcctcaaggggaagttta
gacagttctcgttctgagaaagacagaagtttggagagagagcgaggtattggcctcagt
gcttaccatccaacaacagaaaatgcaggaacctcatcaaaacgaggtctgcagatcact
accactgcagcccagatagccaaagttatggaagaagtatcagccattcatacctcccag
gacgacagaagttctgcttctaccaccgagttccattgtgtggcagacgacaggagtgcg
gcacgaagaagctctgcctcccacacacactcaaacacatacaacttcactaagtcggaa
aattcaaataggacatgctctatgccttatgccaaagtggaatataaacgatcttcaaat
gacagtttaaatagtgtcactagtagtgatggatatggtaaaagaggccaaatgaaaccc
tcagttgaatcctattctgaagatgatgaaagtaaattttgcagttatggtcagtatcca
gctgacctagcccataagatacacagtgcaaatcatatggatgataatgatggagaactg
gatacaccaataaattacagtcttaaatattcagatgagcagttgaactcaggaaggcag
agtccctcacagaatgaaaggtgggcaagaccaaagcatgtgatagaagatgaaataaag
caaaacgagcaaagacaagcaagaagccagaacaccagttatcctgtctattctgagaat
accgatgacaaacacctcaaattccaaccacattttggacaacaagaatgtgtttcccca
tataggtcaaggggaaccagtggttcagaaacaaatcgaatgggttctagtcatgcaatt
aatcaaaatgtaaaccagtctctgtgtcaggaagatgattatgaagatgataaacctacc
aactacagtgaacgttattctgaggaagaacaacatgaagaagaagaagagagaccgaca
aattatagcataaaatataatgaagagaaacatcatgtggatcagcctattgattatagt
ttaaaatatgccactgacatttcttcctcacaaaaaccatcattttcattctcaaagaat
tcatcagcacaaagcactaaacctgaacatctctctccaagcagcgagaatacagctgta
cctccatctaatgccaaaaggcagaatcagctgcgtccaagttcagcacaaagaaatggc
cagactcaaaaaggcactacttgcaaagtcccctccatcaaccaagaaacaatacagact
tactgcgtagaagacaccccaatatgtttttcaaggtgcagttcattatcatcactgtca
tcagctgacgatgaaataggatgtgatcagacaacacaggaagcagattctgctaatact
ctgcagacagcagaagtaaaagagaatgatgtaactcggtcagctgaagatcctgcaact
gaagttccagcagtgtcccagaatgctagagccaaacccagccgactccaggcttctggc
ttatcttcagaatcaaccaggcataataaagctgttgagttttcttcaggagccaagtct
ccctccaaaagtggtgctcagacacccaaaagtcccccagaacactatgtccaggagact
ccgctcgtattcagcaggtgtacttctgtcagctcccttgacagttttgagagtcgctcc
attgccagctctgttcagagtgagccatgtagtggaatggtgagtggcatcataagcccc
agtgaccttccagatagtcctgggcagaccatgccaccaagcagaagcaaaacccctcca
cctcctccacagacagtgcaggccaagagagaggtgccaaaaagtaaagtccctgctgct
gagaagagagagagtgggcctaagcagactgctgtaaatgctgccgtgcagagggtgcag
gtccttccagacgtggatactttgttacacttcgccacagaaagtactccagacgggttt
tcttgttcctccagcctaagtgctctgagcctggatgagccatttatacagaaagatgta
gaattaagaatcatgcctccagttcaggaaaacgacaatgggaatgaaactgaatcagaa
cagcctgaggaatcaaatgaaaaccaggataaagaggtagaaaagcctgactctgaaaaa
gacttattagatgattctgatgacgatgatattgaaatattagaagaatgtattatttca
gccatgccaacaaagtcatcacgcaaagccaaaaaactagcccagactgcttcaaaatta
cctccacctgtggcaaggaaaccaagtcagctacctgtgtataaacttctgccagcacag
aataggctgcaggcacaaaaacatgttagctttacaccaggggatgatgtgccccgggtg
tactgtgtagaagggacacctataaacttttccacagcaacgtctctaagtgatctgaca
atagagtcccctccaaatgaattggctactggagatggggtcagagcgggtatacagtca
ggtgaatttgaaaaacgagataccattcctacagaaggcagaagtacagatgatgctcag
cgaggaaaaatctcatctatagttacaccagacctggatgacaacaaagcagaggaagga
gatattcttgcagaatgtatcaattctgctatgcccaaaggaaaaagccacaagcctttc
cgagtgaaaaagataatggaccaagtccaacaagcatcctcgacttcatctggagctaac
aaaaatcaagtagacactaagaaaaagaagcctacttcaccagtaaagcccatgccacaa
aatactgaatatagaacgcgtgtgagaaagaatacagactcaaaagttaatgtaaatact
gaagaaactttctcagacaacaaagactcaaagaaaccaagcttacaaaccaatgccaag
gccttcaatgaaaagctacctaacaatgaagacagagtgcgggggagcttcgccttggac
tcaccgcatcactacacccctattgaggggacgccgtactgcttttcccgaaatgactcc
ttgagttctctggattttgatgatgacgatgttgacctttccagggaaaaggccgagtta
agaaagggcaaagaaagcaaggattccgaagccaaagttacctgccgcccagaaccaaac
tcaagccagcaggcagctagtaagtcacaagccagtataaaacatccagcaaacagagca
cagtccaaaccagtgctgcagaaacagcccactttcccccagtcctccaaagacggacca
gatagaggggcagcaactgacgaaaaactgcagaattttgctattgaaaatactccagtt
tgcttttctcgaaattcctctctgagttcccttagtgacattgaccaggaaaacaacaat
aacaaagaaagtgaaccaatcaaagaagctgaacctgccaactcacaaggagagcccagt
aagcctcaggcatccgggtatgctcccaagtccttccacgtcgaagacacccctgtctgt
ttctcaagaaacagctctctcagttctcttagcattgactctgaggacgacctgttacag
gagtgtataagttctgccatgccaaaaaagaaaaggccttcaagactcaagagtgagagc
gaaaagcagagccctagaaaagtgggtggcatattagctgaagacctgacgcttgatttg
aaagatctacagaggccagattcagaacacgctttctcccccgactcagaaaattttgac
tggaaagctattcaggaaggcgcaaactccatagtaagtagtttgcaccaagctgctgca
gccgccgcgtgcttatctagacaagcgtcatccgactcagattccattctgtcactaaag
tccggcatttctctgggatcgccttttcatcttacacctgatcaagaggaaaagccattc
acaagcaataaaggcccaagaattctcaaacctggagagaaaagcacattagaagcaaaa
aaaatagaatctgaaaacaaaggaatcaaaggcgggaaaaaggtttataaaagcttgatt
acgggaaagattcgctccaattcagaaatttccagccaaatgaaacaacccctcccgaca
aacatgccttcaatctcaagaggcaggacgatgattcacatcccagggcttcggaatagc
tcctctagtacaagccctgtctctaagaaaggcccacccctcaagactccagcctctaaa
agccccagtgaagggccgggagctaccacttctcctcgaggaactaagccagcaggaaag
tcagagcttagccctatcaccaggcaaacttcccaaatcagtgggtcaaataaggggtct
tctagatcaggatctagagactccactccctcaagacctacacagcaaccattaagtagg
ccaatgcagtctccagggcgaaactcaatttcccctggtagaaatggaataagccctcct
aacaaactgtctcagctgcccagaacatcatctcccagtactgcttcaactaagtcctcc
ggttctgggaaaatgtcatatacatccccaggtagacagctgagccaacaaaatcttacc
aaacaagcaagtttatccaagaatgccagcagtatccccagaagtgagtcggcatctaaa
ggactgaatcagatgagtaacggcaatgggtcaaataaaaaggtagaactttctagaatg
tcttcaactaaatcaagtggaagtgaatcagacagatcagaaaggcctgcattagtacgc
cagtctactttcatcaaagaagccccaagcccaaccctgaggaggaaactggaggaatct
gcctcatttgaatccctttctccatcttctagaccagattctcccaccaggtcgcaggca
cagaccccagttttaagcccttcccttcctgatatgtctctgtccacacatccatctgtt
caggcaggtgggtggcgaaagctcccgcctaatctcagccccactatcgagtataatgac
ggaaggcccacaaaacggcatgatattgcacgctcccattctgaaagtccttccagacta
ccaatcaaccgggcgggaacctggaagcgtgaacacagcaaacattcctcgtcccttcct
cgagtgagtacttggagaagaactggaagctcatcttctattctttctgcttcatcagag
tccagtgaaaaagcaaaaagtgaggatgaaaggcatgtgagctccatgccagcacccaga
cagatgaaggaaaaccaggtgcccaccaaaggaacatggaggaaaatcaaggaaagtgac
atttctcccacaggcatggcttctcagagcgcttcctcaggtgctgccagtggtgctgaa
tccaagcctctgatctatcagatggcacctcctgtctctaaaacagaggatgtttgggtg
agaattgaggactgccccattaacaaccctagatctggacggtcccccacaggcaacacc
cccccagtgattgacagtgtttcagagaagggaagttcaagcattaaagattcaaaagac
acccatgggaaacagagtgtgggcagtggcagtcctgtgcaaaccgtgggtctggaaacc
cgcctcaactcctttgttcaggtagaggccccagaacagaaaggaactgaggcaaaacca
ggacagagtaacccagtctctatagcagagactgctgagacgtgtatagcagagcgtacc
cctttcagttccagtagctccagcaagcacagctcacctagcgggactgttgctgccaga
gtgacaccttttaattacaaccctagccctaggaagagcagcgcagacagcacttcagcc
cggccgtctcagatccctacgccagtgagcaccaacacgaagaagagagattcgaagact
gacagcacagaatccagtggagcccaaagtcctaaacgccattccgggtcttacctcgtg
acgtctgtttaa
DBGET
integrated database retrieval system
