Mus musculus (house mouse): 11937
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Entry
11937 CDS
T01002
Symbol
Atp2a1, SERCA1
Name
(RefSeq) ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04020
Calcium signaling pathway
mmu04022
cGMP-PKG signaling pathway
mmu04024
cAMP signaling pathway
mmu04148
Efferocytosis
mmu04260
Cardiac muscle contraction
mmu04261
Adrenergic signaling in cardiomyocytes
mmu04380
Osteoclast differentiation
mmu04919
Thyroid hormone signaling pathway
mmu04972
Pancreatic secretion
mmu05010
Alzheimer disease
mmu05017
Spinocerebellar ataxia
mmu05022
Pathways of neurodegeneration - multiple diseases
mmu05410
Hypertrophic cardiomyopathy
mmu05412
Arrhythmogenic right ventricular cardiomyopathy
mmu05414
Dilated cardiomyopathy
mmu05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
11937 (Atp2a1)
04024 cAMP signaling pathway
11937 (Atp2a1)
04022 cGMP-PKG signaling pathway
11937 (Atp2a1)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
11937 (Atp2a1)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
11937 (Atp2a1)
09153 Circulatory system
04260 Cardiac muscle contraction
11937 (Atp2a1)
04261 Adrenergic signaling in cardiomyocytes
11937 (Atp2a1)
09154 Digestive system
04972 Pancreatic secretion
11937 (Atp2a1)
09158 Development and regeneration
04380 Osteoclast differentiation
11937 (Atp2a1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
11937 (Atp2a1)
05017 Spinocerebellar ataxia
11937 (Atp2a1)
05022 Pathways of neurodegeneration - multiple diseases
11937 (Atp2a1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
11937 (Atp2a1)
05412 Arrhythmogenic right ventricular cardiomyopathy
11937 (Atp2a1)
05414 Dilated cardiomyopathy
11937 (Atp2a1)
05415 Diabetic cardiomyopathy
11937 (Atp2a1)
Enzymes [BR:
mmu01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
11937 (Atp2a1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
E1-E2_ATPase
Cation_ATPase_C
Cation_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
CA109-like
Motif
Other DBs
NCBI-GeneID:
11937
NCBI-ProteinID:
NP_031530
MGI:
105058
Ensembl:
ENSMUSG00000030730
UniProt:
Q8R429
LinkDB
All DBs
Position
7:complement(126045032..126062245)
Genome browser
AA seq
994 aa
AA seq
DB search
MEAAHSKSTEECLSYFGVSETTGLTPDQVKRHLEKYGPNELPAEEGKSLWELVVEQFEDL
LVRILLLAACISFVLAWFEEGEETVTAFVEPFVILLILIANAIVGVWQERNAENAIEALK
EYEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILSIKSTTLRVDQSIL
TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAVGIVATTGVSTEIGKIRDQMA
ATEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCKMFIIDKVDGDVCSLNEFSITGSTYAPEGEVLKNDKPVRAGQYDGLVELATICALC
NDSSLDFNETKGVYEKVGEATETALTTLVEKMNVFNTEVRSLSKVERANACNSVIRQLMK
KEFTLEFSRDRKSMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPLTGP
VKEKIMSVIKEWGTGRDTLRCLALATRDTPPKREEMVLDDSAKFMEYEMDLTFVGVVGML
DPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFSENEEVTDRAYTGREFDD
LPLAEQREACRRACCFARVEPSHKSKIVEYLQSYDEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKTASEMVLADDNFSTIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAA
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMDRPPRSPKEPLISGWLFFRYMAI
GGYVGAATVGAAAWWFLYAEDGPHVSYHQLTHFMQCTEHNPEFDGLDCEVFEAPEPMTMA
LSVLVTIEMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLR
ALDFTQWLMVLKISLPVIGLDELLKFIARNYLEG
NT seq
2985 nt
NT seq
+upstream
nt +downstream
nt
atggaggccgcgcactccaagtccacagaggaatgtttgtcctatttcggggtgagcgag
accacaggccttaccccagaccaagttaagcgacatctggaaaaatacggccccaatgag
ctccctgctgaggaaggcaagtctctgtgggagttggtggtagagcagttcgaagacctg
cttgtgcggattcttctcctggctgcctgcatttcctttgtgctggcctggtttgaggaa
ggcgaagaaaccgtcactgcctttgtggaaccttttgtcattctcttgatcctcattgcc
aacgccattgtgggggtttggcaggaacggaatgcagagaacgctatcgaagcgctgaaa
gaatatgaacccgagatgggaaaggtctatcgggctgaccgaaagtcagtgcaaaggatc
aaggctcgggacatcgttcctggggacatcgtggaggtggccgttggggacaaagtccct
gcagacatccgcatcctctccatcaaatccaccaccctccgggtcgaccagtccatcctg
acaggagagtctgtgtctgtcatcaagcacacagaccctgtccctgacccccgagctgtc
aaccaggacaagaagaacatgctcttctcaggtaccaacatcgcagccggcaaggctgta
ggcatcgtggccaccactggtgtgagtactgagattggcaagatccgagaccagatggct
gccaccgagcaggacaagactccactgcagcagaagcttgacgagtttggggagcagctg
tccaaggtcatctctctcatctgtgtggctgtctggcttatcaacattggccacttcaac
gatcctgtccatgggggctcctggttccggggtgccatttactacttcaagattgctgtg
gccttggctgtggcggccatcccagaagggcttcctgctgtcatcaccacctgcttggct
ttgggtacccgccggatggcaaagaagaacgccatcgtgaggagtctgccctctgtggag
accctgggctgtacctctgtcatctgttctgacaaaacagggaccctcaccaccaaccag
atgtcagtttgcaagatgttcatcattgacaaggtggatggggatgtctgctcactgaac
gagttctccatcactggctctacttatgctcctgagggagaggtcttgaagaatgataag
ccagtccgagcagggcagtatgatgggctggtggagctcgctaccatctgtgccctctgc
aatgattcctccttggactttaatgagaccaaaggtgtctatgagaaggtgggcgaggcc
acggagactgctctcaccaccttggtggagaagatgaacgtattcaacacggaagtgaga
agcctctctaaagtggagcgggccaacgcctgcaattcggtgatccgccaactcatgaag
aaggaattcaccctggaattttcccgagacaggaagtctatgtctgtctactgttcacca
gctaagtcctcacgggctgccgtgggcaacaagatgtttgtcaagggtgcccccgagggg
gtcatcgaccgctgtaactatgtgcgtgttggcacgacccgtgtgccattgacaggcccc
gtgaaggagaagatcatgtctgtgatcaaggagtggggcactggtcgggacacactgcgg
tgcctggcgctggccacccgcgacacgccccccaaacgcgaggagatggttctggatgat
tcagccaagttcatggagtatgagatggacctgacgtttgttggtgttgtgggcatgttg
gatccaccccgcaaggaggtcacaggctctatccagctgtgtcgtgatgctgggatccga
gtgatcatgatcactggggacaacaagggtacagccattgccatctgccgacgaattggc
atcttttcggagaatgaggaagtgacagaccgtgcctacactggccgtgagtttgacgat
ctgcccctggccgagcagcgggaggcctgcagacgcgcctgctgctttgctcgtgtggag
ccctcacacaagtccaagattgtggagtacctgcagtcctacgatgagatcacagccatg
acaggggatggtgtcaatgatgcccctgctctgaagaaggccgagattggcattgccatg
ggatctggtactgctgtggctaagacggcctctgaaatggtactggccgatgataacttc
tccaccatcgtggctgccgtggaggaaggccgcgccatctacaacaacatgaagcagttc
atccgctacctcatctcctccaatgtgggcgaggtggtctgtatcttcttgacagcagcc
ttggggctgcctgaggctctgatccctgtgcagctgctctgggtgaacttggtgactgat
gggctcccggctactgccctgggattcaacccacctgacctggacatcatggaccgcccc
cccaggagtcccaaggagcctcttatcagtggctggctctttttccgctacatggcaatt
gggggctatgtgggtgcagccactgtaggagcagctgcctggtggtttttgtatgcagag
gacgggcctcatgtcagctaccatcagctgactcatttcatgcagtgcactgagcacaac
cctgaattcgatggcctggactgtgaggtctttgaggcccccgagcccatgaccatggcc
ttgtctgtgttggtgaccatcgagatgtgcaatgctctcaacagcctgtctgagaaccag
tccctactgcggatgccaccctgggtgaacatctggctgctgggttccatctgcctgtcc
atgtccctccacttcctcatcctctatgtcgaccccctgccgatgatcttcaagctccgg
gccctggactttacccagtggctcatggtcctcaagatctcactgccagtcatcgggctg
gatgagcttctcaagttcattgctcggaactatctggagggataa
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