Mus musculus (house mouse): 12229
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Entry
12229 CDS
T01002
Symbol
Btk, xid
Name
(RefSeq) Bruton agammaglobulinemia tyrosine kinase
KO
K07370
Bruton agammaglobulinemia tyrosine kinase [EC:
2.7.10.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04064
NF-kappa B signaling pathway
mmu04380
Osteoclast differentiation
mmu04611
Platelet activation
mmu04662
B cell receptor signaling pathway
mmu04664
Fc epsilon RI signaling pathway
mmu05169
Epstein-Barr virus infection
mmu05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
12229 (Btk)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
12229 (Btk)
04662 B cell receptor signaling pathway
12229 (Btk)
04664 Fc epsilon RI signaling pathway
12229 (Btk)
09158 Development and regeneration
04380 Osteoclast differentiation
12229 (Btk)
09160 Human Diseases
09172 Infectious disease: viral
05169 Epstein-Barr virus infection
12229 (Btk)
09163 Immune disease
05340 Primary immunodeficiency
12229 (Btk)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
12229 (Btk)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
12229 (Btk)
Protein kinases [BR:
mmu01001
]
Non-receptor tyrosine kinases
TEC family
12229 (Btk)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
PH
BTK
SH3_9
SH3_2
Kinase-like
SH3_10
SH3_3
ABC1
Pkinase_fungal
Kdo
Haspin_kinase
SH3_4
Dicer_dsRBD
Motif
Other DBs
NCBI-GeneID:
12229
NCBI-ProteinID:
NP_038510
MGI:
88216
Ensembl:
ENSMUSG00000031264
UniProt:
P35991
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:complement(133443083..133484366)
Genome browser
AA seq
659 aa
AA seq
DB search
MAAVILESIFLKRSQQKKKTSPLNFKKRLFLLTVHKLSYYEYDFERGRRGSKKGSIDVEK
ITCVETVIPEKNPPPERQIPRRGEESSEMEQISIIERFPYPFQVVYDEGPLYVFSPTEEL
RKRWIHQLKNVIRYNSDLVQKYHPCFWIDGQYLCCSQTAKNAMGCQILENRNGSLKPGSS
HRKTKKPLPPTPEEDQILKKPLPPEPTAAPISTTELKKVVALYDYMPMNANDLQLRKGEE
YFILEESNLPWWRARDKNGQEGYIPSNYITEAEDSIEMYEWYSKHMTRSQAEQLLKQEGK
EGGFIVRDSSKAGKYTVSVFAKSTGEPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELIN
YHQHNSAGLISRLKYPVSKQNKNAPSTAGLGYGSWEIDPKDLTFLKELGTGQFGVVKYGK
WRGQYDVAIKMIREGSMSEDEFIEEAKVMMNLSHEKLVQLYGVCTKQRPIFIITEYMANG
CLLNYLREMRHRFQTQQLLEMCKDVCEAMEYLESKQFLHRDLAARNCLVNDQGVVKVSDF
GLSRYVLDDEYTSSVGSKFPVRWSPPEVLMYSKFSSKSDIWAFGVLMWEIYSLGKMPYER
FTNSETAEHIAQGLRLYRPHLASERVYTIMYSCWHEKADERPSFKILLSNILDVMDEES
NT seq
1980 nt
NT seq
+upstream
nt +downstream
nt
atggctgcagtgatactggagagcatctttctgaagcgctcccagcagaaaaagaaaaca
tcacctttaaacttcaagaagcgcctgtttctcttgactgtacacaaactttcatactat
gaatatgactttgaacgtgggagaagaggcagtaagaaaggttcaatagatgttgagaag
atcacctgtgttgaaacagtaattcctgaaaaaaatcccccaccagaaagacagattccg
aggagaggtgaggagtctagtgaaatggaacagatttcaatcattgaaaggttcccgtac
ccattccaggttgtatatgatgaaggacctctctatgttttctccccaactgaagagctg
agaaagcgctggattcaccagctcaaaaatgtaatccggtacaatagtgacctggtacag
aaataccatccttgcttctggattgatggacagtatctctgctgctctcagacagccaag
aatgctatgggctgccaaattttggagaacaggaatggaagcttaaaacctgggagttct
catcgaaaaacgaaaaagcctcttccccctaccccagaggaagatcagatcttgaaaaaa
ccgcttcccccggagccaacagcagcaccaatctccacaaccgagctgaaaaaggtcgtg
gccctttatgattacatgccaatgaacgcaaatgacttacaattgcgaaagggcgaggag
tattttatcctggaggagagcaacctaccgtggtggcgagcacgagataaaaatgggcag
gaaggctacatcccaagtaactatatcactgaagctgaggactccatagagatgtatgag
tggtattccaagcacatgactcgaagtcaagctgagcaactgctaaagcaagaggggaaa
gaaggaggtttcattgtcagagactccagcaaagctggaaaatacaccgtgtctgtgttt
gctaaatctactggggagcctcaaggggtgatccgccattacgttgtgtgttccacgcca
cagagccagtattacctggctgagaaacacctcttcagcaccatccctgagctcattaac
taccatcaacacaactctgcaggcctcatatccaggctgaaatatcctgtgtctaaacaa
aacaaaaacgcgccttctactgcaggcctgggctatggatcatgggaaattgatccaaag
gacctcaccttcttgaaggagcttgggactggacaattcggtgtcgtgaaatatgggaag
tggaggggccaatatgatgtggccatcaagatgatcagagaaggttccatgtcggaggat
gaattcattgaagaagccaaagtcatgatgaatctttcccatgagaagctggtgcagttg
tatggcgtctgcaccaaacaacgccccatcttcatcatcaccgagtacatggctaatggc
tgcctcttgaactacctgagggagatgcggcaccgcttccagacacagcagctgcttgag
atgtgcaaagatgtctgtgaagcaatggaatacttggagtcgaagcagttccttcacaga
gacctggcagctcgaaactgtttggtaaacgatcaaggagttgtgaaagtatctgacttt
ggcctgtctaggtatgtccttgatgatgagtacaccagctctgtaggctccaagtttcca
gtccggtggtctccaccagaagtgcttatgtatagcaagttcagcagcaaatctgacatc
tgggcttttggggttttaatgtgggagatctactccctggggaagatgccgtatgagaga
tttactaacagtgagacagcagaacacattgctcaaggcttacgtctctacaggcctcat
ctggcatcagagagggtatataccatcatgtacagctgctggcacgagaaagcagatgaa
cgtcctagtttcaaaattctcttgagtaacattctagatgtgatggatgaagaatcctga
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