Mus musculus (house mouse): 12334
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Entry
12334 CDS
T01002
Symbol
Capn2, CALP80, Capa-2, Capa2, m-calpain, m-calpin
Name
(RefSeq) calpain 2
KO
K03853
calpain-2 [EC:
3.4.22.53
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04141
Protein processing in endoplasmic reticulum
mmu04210
Apoptosis
mmu04217
Necroptosis
mmu04218
Cellular senescence
mmu04510
Focal adhesion
mmu05010
Alzheimer disease
mmu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
12334 (Capn2)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
12334 (Capn2)
04217 Necroptosis
12334 (Capn2)
04218 Cellular senescence
12334 (Capn2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
12334 (Capn2)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
12334 (Capn2)
05022 Pathways of neurodegeneration - multiple diseases
12334 (Capn2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mmu01002
]
12334 (Capn2)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.22 Cysteine endopeptidases
3.4.22.53 calpain-2
12334 (Capn2)
Peptidases and inhibitors [BR:
mmu01002
]
Cysteine peptidases
Family C2: calpain family
12334 (Capn2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Peptidase_C2
Calpain_III
EF-hand_1
EF-hand_6
EF-hand_8
EF-hand_7
Motif
Other DBs
NCBI-GeneID:
12334
NCBI-ProteinID:
NP_033924
MGI:
88264
Ensembl:
ENSMUSG00000026509
UniProt:
O08529
LinkDB
All DBs
Position
1:complement(182294818..182345175)
Genome browser
AA seq
700 aa
AA seq
DB search
MAGIAIKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDPSFPALPSSLGY
KELGPYSSKTRGIEWKRPTEICADPQFIIGGATRTDICQGALGDCWLLAAIASLTLNEEI
LARVVPPDQSFQENYAGIFHFQFWQYGEWVEVVVDDRLPTKDGELLFVHSAEGSEFWSAL
LEKAYAKINGCYEALSGGATTEGFEDFTGGIAEWYELRKPPPNLFKIIQKALEKGSLLGC
SIDITSAADSEAVTYQKLVKGHAYSVTGAEEVESSGSLQKLIRIRNPWGQVEWTGKWNDN
CPSWNTVDPEVRANLTERQEDGEFWMSFSDFLRHYSRLEICNLTPDTLTCDSYKKWKLTK
MDGNWRRGSTAGGCRNYPNTFWMNPQYLIKLEEEDEDEEDGERGCTFLVGLIQKHRRRQR
KMGEDMHTIGFGIYEVPEELTGQTNIHLGKNFFLTTRARERSDTFINLREVLNRFKLPPG
EYVLVPSTFEPHKDGDFCIRVFSEKKADYQAVDDEIEANIEEIDANEEDIDDGFRRLFVQ
LAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYIL
WTKIQKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELIIDFD
NFVRCLVRLETLFKIFKQLDPENTGTIQLNLASWLSFSVL
NT seq
2103 nt
NT seq
+upstream
nt +downstream
nt
atggcgggcatcgcgataaagctggccaaggaccgcgaagcggccgaggggctggggtcg
catgagagagccatcaagtacctcaaccaggactacgagacgctgcggaacgagtgcctg
gaggccggggcgctcttccaggatccttccttccccgccctgccgtcatccttgggctat
aaggagttggggccctactccagcaaaactcggggcatcgaatggaagcggcccacggag
atctgcgctgacccccagttcattattggaggagccacccgcacagacatctgccaagga
gccctgggggactgctggctgctggctgccatcgcctccctcaccttgaatgaggaaatc
ctggctcgggttgtgcctccagatcagagcttccaggaaaactatgcaggcatcttccac
ttccagttctggcaatatggcgagtgggtggaggtggtggtggacgacaggctgcccact
aaggacggggagctgctctttgtgcattcagctgaagggagtgagttctggagtgccctt
ctggagaaagcctatgccaagatcaatgggtgctatgaagcactctcagggggtgccacc
acggaaggctttgaagacttcacaggaggcattgctgagtggtatgagctgaggaagcct
cctcccaacttgttcaagatcatccagaaggctttggagaaaggttctctgcttggctgc
tctatcgatatcaccagcgctgcagattctgaggccgttacgtaccagaagttggtgaaa
ggacatgcgtactctgtcaccggagccgaggaggttgaaagttcaggaagcctgcagaaa
ttgatccgcatcaggaatccctggggacaagtagagtggaccgggaagtggaatgacaat
tgccccagctggaacacggttgacccagaagtaagggcaaatctaaccgaacggcaggag
gacggagaattctggatgtccttcagtgacttcctgagacactactctcgcctggagatc
tgcaacctgaccccggacaccctcacctgtgactcctataagaagtggaaactcaccaag
atggatgggaactggaggcgaggctccaccgcagggggctgcaggaattacccaaatacc
ttctggatgaaccctcagtacctaattaagctggaggaagaagacgaagatgaggaggat
ggggagagaggctgtaccttcctggtgggtctcatccagaagcaccggcgacggcagagg
aagatgggcgaggacatgcacaccattggcttcggcatctatgaggttccagaggagcta
acagggcagaccaacatccacctcggcaaaaactttttcctcacaacccgagccagggag
cggtcagataccttcattaacctccgcgaggtcctcaaccgcttcaagctgcccccggga
gagtatgtcctcgttccctccaccttcgaaccccacaaggatggcgatttctgcatccga
gtcttctcggagaagaaggctgactaccaagctgttgatgacgagatcgaggccaacatt
gaagagattgacgccaatgaggaggacattgacgatggattccgaaggctctttgttcag
ctggctggagaggatgcagagatctctgcctttgagctgcagaccatcttaagaagagtt
ctagccaaacgccaagacatcaagtcagacggcttcagcatcgagacctgtaagatcatg
gtggacatgctggatgaagatgggagtggcaagcttggcctgaaggagttctacatcctc
tggacgaagattcagaaataccaaaaaatctaccgggaaatcgatgtggacaggtctgga
accatgaattcctacgagatgcggaaagcactggaagaagcaggtttcaagctgccctgt
caacttcatcaagtcatcgttgcccggtttgcagacgacgagctaatcatcgactttgac
aattttgtgcggtgtttggtccgtctggaaacgctattcaagatattcaagcagctagac
cctgagaacactggaacgatacagctcaaccttgcttcgtggctgagtttttcagtactc
tga
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