Mus musculus (house mouse): 12402
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Entry
12402 CDS
T01002
Symbol
Cbl, 4732447J05Rik, Cbl-2, c-Cbl
Name
(RefSeq) Casitas B-lineage lymphoma
KO
K04707
E3 ubiquitin-protein ligase CBL [EC:
2.3.2.27
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04012
ErbB signaling pathway
mmu04120
Ubiquitin mediated proteolysis
mmu04144
Endocytosis
mmu04910
Insulin signaling pathway
mmu05100
Bacterial invasion of epithelial cells
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
12402 (Cbl)
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
12402 (Cbl)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
12402 (Cbl)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
12402 (Cbl)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
12402 (Cbl)
05205 Proteoglycans in cancer
12402 (Cbl)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
12402 (Cbl)
09171 Infectious disease: bacterial
05100 Bacterial invasion of epithelial cells
12402 (Cbl)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
12402 (Cbl)
04121 Ubiquitin system [BR:
mmu04121
]
12402 (Cbl)
Enzymes [BR:
mmu01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.27 RING-type E3 ubiquitin transferase
12402 (Cbl)
Membrane trafficking [BR:
mmu04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
12402 (Cbl)
Ubiquitin system [BR:
mmu04121
]
Ubiquitin ligases (E3)
Single Ring-finger type E3
CBL proteins
12402 (Cbl)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Cbl_N
Cbl_N3
Cbl_N2
Prok-RING_4
zf-C3HC4_3
zf-C3HC4
zf-RING_2
UBA
zf-C3HC4_2
zf-RING_UBOX
zf-RING_5
zf-rbx1
zf-C3HC4_4
Motif
Other DBs
NCBI-GeneID:
12402
NCBI-ProteinID:
NP_031645
MGI:
88279
Ensembl:
ENSMUSG00000034342
UniProt:
P22682
Structure
PDB
LinkDB
All DBs
Position
9:complement(44054273..44145556)
Genome browser
AA seq
913 aa
AA seq
DB search
MAGNVKKSSGAGGGGSGGSGAGGLIGLMKDAFQPHHHHHHLSPHPPCTVDKKMVEKCWKL
MDKVVRLCQNPKLALKNSPPYILDLLPDTYQHLRTVLSRYEGKMETLGENEYFRVFMENL
MKKTKQTISLFKEGKERMYEENSQPRRNLTKLSLIFSHMLAELKGIFPSGLFQGDTFRIT
KADAAEFWRKAFGEKTIVPWKSFRQALHEVHPISSGLEAMALKSTIDLTCNDYISVFEFD
IFTRLFQPWSSLLRNWNSLAVTHPGYMAFLTYDEVKARLQKFIHKPGSYIFRLSCTRLGQ
WAIGYVTADGNILQTIPHNKPLFQALIDGFREGFYLFPDGRNQNPDLTGLCEPTPQDHIK
VTQEQYELYCEMGSTFQLCKICAENDKDVKIEPCGHLMCTSCLTSWQESEGQGCPFCRCE
IKGTEPIVVDPFDPRGSGSLLRQGAEGAPSPNYDDDDDERADDSLFMMKELAGAKVERPS
SPFSMAPQASLPPVPPRLDLLQQRAPVPASTSVLGTASKAASGSLHKDKPLPIPPTLRDL
PPPPPPDRPYSVGAETRPQRRPLPCTPGDCPSRDKLPPVPSSRPGDSWLSRPIPKVPVAT
PNPGDPWNGRELTNRHSLPFSLPSQMEPRADVPRLGSTFSLDTSMTMNSSPVAGPESEHP
KIKPSSSANAIYSLAARPLPMPKLPPGEQGESEEDTEYMTPTSRPVGVQKPEPKRPLEAT
QSSRACDCDQQIDSCTYEAMYNIQSQALSVAENSASGEGNLATAHTSTGPEESENEDDGY
DVPKPPVPAVLARRTLSDISNASSSFGWLSLDGDPTNFNEGSQVPERPPKPFPRRINSER
KASSYQQGGGATANPVATAPSPQLSSEIERLMSQGYSYQDIQKALVIAHNNIEMAKNILR
EFVSISSPAHVAT
NT seq
2742 nt
NT seq
+upstream
nt +downstream
nt
atggccggcaacgtgaagaagagctcgggcgccggcggcggcggctctgggggctcggga
gcgggcggcctgatcgggctcatgaaggacgccttccagccgcaccaccaccaccaccac
ctcagcccgcaccctccctgcacggtggacaagaagatggtggagaagtgctggaagctc
atggacaaggtggtgcggttgtgtcaaaacccaaagctggcgctcaagaacagcccgcct
tatatcttagacctgctgcctgacacctaccagcacctccgcactgtcttgtcaagatat
gaggggaagatggagacgcttggagaaaatgagtatttcagggtgttcatggaaaatttg
atgaagaaaactaagcagactatcagcctcttcaaggagggaaaagaaaggatgtatgag
gagaattcccagcctaggcgaaacctgaccaaattatccctgatcttcagccacatgctg
gcagaactgaaaggcatctttccgagcggactcttccaaggagacactttccggattact
aaagctgatgctgccgaattttggagaaaagcttttggtgaaaagacgatagtcccgtgg
aagagctttcgacaggccctgcatgaagtgcatcccatcagttctgggctggaggccatg
gctctgaagtccactattgatctgacctgcaatgattatatttctgtctttgaatttgat
atttttacacggctgtttcagccctggtcctctttgctcagaaattggaacagccttgct
gtaactcaccctggttacatggctttcctgacatacgatgaagtgaaagcgcgcctgcag
aagttcatccacaaacctggcagttacatctttcggctgagctgtactcgtttgggtcag
tgggctattgggtatgttactgccgatgggaacattctgcagacaatcccacacaataaa
ccgctcttccaagcactgattgatggcttcagggaaggcttctatttgtttcctgatgga
cgaaatcaaaatcctgacctgacaggtttatgtgaaccaactcctcaagatcatatcaaa
gtaacccaggaacaatatgaattatactgtgaaatgggctccacatttcaactgtgtaag
atatgtgctgagaatgataaggatgtgaagattgagccctgtggacacctcatgtgcaca
tcctgcctcacgtcgtggcaggaatcagaaggtcagggctgtcctttttgccgatgtgaa
atcaaaggtactgagcccatcgtggtggatccgtttgaccccagaggcagtggcagccta
ttaaggcaaggagcagaaggtgctccttccccaaattacgacgatgatgatgatgaacga
gctgatgattctctcttcatgatgaaggagttggcaggtgccaaggtggaaaggccttcc
tctccattctccatggccccacaagcttcccttcctccagtgccaccaagacttgacctt
ctacagcagcgagcacctgttcctgccagcacttcagttctggggactgcttccaaggct
gcttctggctcccttcataaagacaaaccattgccaatacctcccacacttcgagatctt
ccaccaccaccccctccagaccggccttactctgttggagcagaaacaaggcctcagaga
cgccctctgccttgtacaccaggcgattgtccatctagagacaaactgccccctgtccct
tctagccgcccaggggactcgtggttgtctcggccaatccctaaagtaccagtagctact
ccaaaccctggtgatccttggaatgggagagaattgaccaatcggcactcgcttccattc
tcattgccctcacaaatggaacccagagcagatgtccctaggcttggaagcacatttagt
ctggatacctctatgactatgaatagcagcccagtagcaggtccagagagtgagcaccca
aagatcaagccttcctcgtctgccaacgccatttactctctggctgccaggcctcttcct
atgccaaaactgccacctggggagcaaggggaaagtgaagaggacacagaatatatgact
cccacatctaggcctgtaggggttcagaagccagagcccaaacggccgttagaggcaacc
cagagttcacgagcatgtgactgtgaccagcagatcgacagctgtacctatgaagcgatg
tataacatccagtcccaagcactgtctgtagcagaaaacagcgcctctggggaagggaat
ctggccacagctcacacgagtactggccctgaggaatccgaaaacgaggatgatggctat
gatgtgcctaagccacccgtgccagctgtactggcccgccggaccctgtctgacatctcc
aatgccagctcctcctttggctggttgtctttggatggtgaccctacaaacttcaatgag
ggttcccaagttcctgagcggccccccaaaccattccctcggagaatcaactcagaacga
aaagccagtagctatcaacaaggcggaggtgccactgctaaccctgtggccacagcaccc
tcaccgcagctctcaagtgagattgaacgcctcatgagtcagggctattcctaccaggac
attcagaaagctttggtcattgcccacaacaacattgagatggctaaaaacatcctccgg
gaatttgtttctatttcttctcctgctcacgtagccacctag
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