Mus musculus (house mouse): 12914 Help Entry 12914             CDS       T01002                                  Symbol Crebbp, CBP, CBP/p300, KAT3A, p300/CBP Name (RefSeq) CREB binding protein   KO K04498   E1A/CREB-binding protein [EC:2.3.1.48] Organism mmu  Mus musculus (house mouse) Pathway mmu03083   Polycomb repressive complex mmu03250   Viral life cycle - HIV-1 mmu04024   cAMP signaling pathway mmu04066   HIF-1 signaling pathway mmu04068   FoxO signaling pathway mmu04110   Cell cycle mmu04310   Wnt signaling pathway mmu04330   Notch signaling pathway mmu04350   TGF-beta signaling pathway mmu04520   Adherens junction mmu04630   JAK-STAT signaling pathway mmu04720   Long-term potentiation mmu04916   Melanogenesis mmu04919   Thyroid hormone signaling pathway mmu04922   Glucagon signaling pathway mmu04935   Growth hormone synthesis, secretion and action mmu05016   Huntington disease mmu05152   Tuberculosis mmu05161   Hepatitis B mmu05164   Influenza A mmu05165   Human papillomavirus infection mmu05166   Human T-cell leukemia virus 1 infection mmu05167   Kaposi sarcoma-associated herpesvirus infection mmu05200   Pathways in cancer mmu05203   Viral carcinogenesis mmu05206   MicroRNAs in cancer mmu05211   Renal cell carcinoma mmu05215   Prostate cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09120 Genetic Information Processing   09126 Chromosome    03083 Polycomb repressive complex     12914 (Crebbp)   09125 Information processing in viruses    03250 Viral life cycle - HIV-1     12914 (Crebbp)  09130 Environmental Information Processing   09132 Signal transduction    04310 Wnt signaling pathway     12914 (Crebbp)    04330 Notch signaling pathway     12914 (Crebbp)    04350 TGF-beta signaling pathway     12914 (Crebbp)    04630 JAK-STAT signaling pathway     12914 (Crebbp)    04066 HIF-1 signaling pathway     12914 (Crebbp)    04068 FoxO signaling pathway     12914 (Crebbp)    04024 cAMP signaling pathway     12914 (Crebbp)  09140 Cellular Processes   09143 Cell growth and death    04110 Cell cycle     12914 (Crebbp)   09144 Cellular community - eukaryotes    04520 Adherens junction     12914 (Crebbp)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     12914 (Crebbp)    04935 Growth hormone synthesis, secretion and action     12914 (Crebbp)    04919 Thyroid hormone signaling pathway     12914 (Crebbp)    04916 Melanogenesis     12914 (Crebbp)   09156 Nervous system    04720 Long-term potentiation     12914 (Crebbp)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     12914 (Crebbp)    05206 MicroRNAs in cancer     12914 (Crebbp)    05203 Viral carcinogenesis     12914 (Crebbp)   09162 Cancer: specific types    05211 Renal cell carcinoma     12914 (Crebbp)    05215 Prostate cancer     12914 (Crebbp)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     12914 (Crebbp)    05161 Hepatitis B     12914 (Crebbp)    05164 Influenza A     12914 (Crebbp)    05167 Kaposi sarcoma-associated herpesvirus infection     12914 (Crebbp)    05165 Human papillomavirus infection     12914 (Crebbp)   09171 Infectious disease: bacterial    05152 Tuberculosis     12914 (Crebbp)   09164 Neurodegenerative disease    05016 Huntington disease     12914 (Crebbp)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03000 Transcription factors [BR:mmu03000]     12914 (Crebbp)    03036 Chromosome and associated proteins [BR:mmu03036]     12914 (Crebbp)    03029 Mitochondrial biogenesis [BR:mmu03029]     12914 (Crebbp) Enzymes [BR:mmu01000]  2. Transferases   2.3  Acyltransferases    2.3.1  Transferring groups other than aminoacyl groups     2.3.1.48  histone acetyltransferase      12914 (Crebbp) Transcription factors [BR:mmu03000]  Eukaryotic type   Other transcription factors    Pocket domain CBP     12914 (Crebbp) Chromosome and associated proteins [BR:mmu03036]  Eukaryotic type   Histone modification proteins    HATs (histone acetyltransferases)     12914 (Crebbp) Mitochondrial biogenesis [BR:mmu03029]  Mitochondrial quality control factors   Regulator of mitochondrial biogenesis    Coactivators     12914 (Crebbp) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  HAT_KAT11 KIX Creb_binding zf-TAZ PHD_P300 RING_CBP-p300 Bromodomain ZZ KIX_2 Npa1 Motif Other DBs NCBI-GeneID:  12914 NCBI-ProteinID:  NP_001020603 MGI:  1098280 Ensembl:  ENSMUSG00000022521 UniProt:  F8VPR5 Q6GQV9 LinkDB All DBs Position 16:complement(3899198..4031864) Genome browser AA seq 2441 aa AA seqDB search MAENLLDGPPNPKRAKLSSPGFSANDNTDFGSLFDLENDLPDELIPNGELSLLNSGNLVP DAASKHKQLSELLRGGSGSSINPGIGNVSASSPVQQGLGGQAQGQPNSTNMASLGAMGKS PLNQGDSSTPNLPKQAASTSGPTPPASQALNPQAQKQVGLVTSSPATSQTGPGICMNANF NQTHPGLLNSNSGHSLMNQAQQGQAQVMNGSLGAAGRGRGAGMPYPAPAMQGATSSVLAE TLTQVSPQMAGHAGLNTAQAGGMTKMGMTGTTSPFGQPFSQTGGQQMGATGVNPQLASKQ SMVNSLPAFPTDIKNTSVTTVPNMSQLQTSVGIVPTQAIATGPTADPEKRKLIQQQLVLL LHAHKCQRREQANGEVRACSLPHCRTMKNVLNHMTHCQAGKACQVAHCASSRQIISHWKN CTRHDCPVCLPLKNASDKRNQQTILGSPASGIQNTIGSVGAGQQNATSLSNPNPIDPSSM QRAYAALGLPYMNQPQTQLQPQVPGQQPAQPPAHQQMRTLNALGNNPMSIPAGGITTDQQ PPNLISESALPTSLGATNPLMNDGSNSGNIGSLSTIPTAAPPSSTGVRKGWHEHVTQDLR SHLVHKLVQAIFPTPDPAALKDRRMENLVAYAKKVEGDMYESANSRDEYYHLLAEKIYKI QKELEEKRRSRLHKQGILGNQPALPASGAQPPVIPPAQSVRPPNGPLPLPVNRMQVSQGM NSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMASVPGMAISPSRMPQPPNMMGTHAN NIMAQAPTQNQFLPQNQFPSSSGAMSVNSVGMGQPAAQAGVSQGQVPGAALPNPLNMLAP QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHPTAPGMTPPQPAAPTQPSTPVSSGQTP TPTPGSVPSAAQTQSTPTVQAAAQAQVTPQPQTPVQPPSVATPQSSQQQPTPVHTQPPGT PLSQAAASIDNRVPTPSSVTSAETSSQQPGPDVPMLEMKTEVQTDDAEPEPTESKGEPRS EMMEEDLQGSSQVKEETDTTEQKSEPMEVEEKKPEVKVEAKEEEENSSNDTASQSTSPSQ PRKKIFKPEELRQALMPTLEALYRQDPESLPFRQPVDPQLLGIPDYFDIVKNPMDLSTIK RKLDTGQYQEPWQYVDDVWLMFNNAWLYNRKTSRVYKFCSKLAEVFEQEIDPVMQSLGYC CGRKYEFSPQTLCCYGKQLCTIPRDAAYYSYQNRYHFCEKCFTEIQGENVTLGDDPSQPQ TTISKDQFEKKKNDTLDPEPFVDCKECGRKMHQICVLHYDIIWPSGFVCDNCLKKTGRPR KENKFSAKRLQTTRLGNHLEDRVNKFLRRQNHPEAGEVFVRVVASSDKTVEVKPGMKSRF VDSGEMSESFPYRTKALFAFEEIDGVDVCFFGMHVQEYGSDCPPPNTRRVYISYLDSIHF FRPRCLRTAVYHEILIGYLEYVKKLGYVTGHIWACPPSEGDDYIFHCHPPDQKIPKPKRL QEWYKKMLDKAFAERIINDYKDIFKQANEDRLTSAKELPYFEGDFWPNVLEESIKELEQE EEERKKEESTAASETPEGSQGDSKNAKKKNNKKTNKNKSSISRANKKKPSMPNVSNDLSQ KLYATMEKHKEVFFVIHLHAGPVISTQPPIVDPDPLLSCDLMDGRDAFLTLARDKHWEFS SLRRSKWSTLCMLVELHTQGQDRFVYTCNECKHHVETRWHCTVCEDYDLCINCYNTKSHT HKMVKWGLGLDDEGSSQGEPQSKSPQESRRLSIQRCIQSLVHACQCRNANCSLPSCQKMK RVVQHTKGCKRKTNGGCPVCKQLIALCCYHAKHCQENKCPVPFCLNIKHKLRQQQIQHRL QQAQLMRRRMATMNTRNVPQQSLPSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVNMSPA GFPNVARTQPPTIVSAGKPTNQVPAPPPPAQPPPAAVEAARQIEREAQQQQHLYRANINN GMPPGRAGMGTPGSQMTPVGLNVPRPNQVSGPVMSSMPPGQWQQAPIPQQQPMPGMPRPV MSMQAQAAVAGPRMPNVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAA FIKQRTAKYVANQPGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPPQP AMGGLNPQGQALNIMNPGHNPNMTNMNPQYREMVRRQLLQHQQQQQQQQQQQQQQQNSAS LAGGMAGHSQFQQPQGPGGYAPAMQQQRMQQHLPIQGSSMGQMAAPMGQLGQMGQPGLGA DSTPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSN QVRSPAPVQSPRPQSQPPHSSPSPRIQPQPSPHHVSPQTGSPHPGLAVTMASSMDQGHLG NPEQSAMLPQLNTPNRSALSSELSLVGDTTGDTLEKFVEGL NT seq 7326 nt NT seq  +upstreamnt  +downstreamnt atggccgagaacttgctggacggaccgcccaaccccaaacgagccaaactcagctcgccc ggcttctccgcgaatgacaacacagattttggatcattgtttgacttggaaaatgacctt cctgatgagctgatccccaatggagaattaagccttttaaacagtgggaaccttgttcca gatgctgcgtccaaacataaacaactgtcagagcttcttagaggaggcagcggctctagc atcaacccagggataggcaatgtgagtgccagcagccctgtgcaacagggccttggtggc caggctcaggggcagccgaacagtacaaacatggccagcttaggtgccatgggcaagagc cctctgaaccaaggagactcatcaacacccaacctgcccaaacaggcagccagcacctct gggcccactccccctgcctcccaagcactgaatccacaagcacaaaagcaagtagggctg gtgaccagtagtcctgccacatcacagactggacctgggatctgcatgaatgctaacttc aaccagacccacccaggccttctcaatagtaactctggccatagcttaatgaatcaggct caacaagggcaagctcaagtcatgaatggatctcttggggctgctggaagaggaagggga gctggaatgccctaccctgctccagccatgcagggggccacaagcagtgtgctggcggag accttgacacaggtttccccacaaatggctggccatgctggactaaatacagcacaggca ggaggcatgaccaagatgggaatgactggtaccacaagtccatttggacaaccctttagt caaactggagggcagcagatgggagccactggagtgaacccccagttagccagcaaacag agcatggtcaatagtttacctgcttttcctacagatatcaagaatacttcagtcaccact gtgccaaatatgtcccagttgcaaacatcagtgggaattgtacccacacaagcaattgca acaggccccacagcagaccctgaaaaacgcaaactgatacagcagcagctggttctactg cttcatgcccacaaatgtcagagacgagagcaagcaaatggagaggttcgagcctgttct ctcccacactgtcgaaccatgaaaaacgttttgaatcacatgacacattgtcaggctggg aaagcctgccaagttgcccattgtgcatcttcacgacaaatcatctctcattggaagaac tgcacacgacatgactgtcctgtttgcctccctttgaaaaatgccagtgacaagcgaaac caacaaaccatcctgggatctccagctagtggaattcaaaacacaattggttctgttggt gcagggcaacagaatgccacttccttaagtaacccaaatcccatagaccccagttccatg cagcgggcctatgctgctctaggactcccctacatgaaccagcctcagacgcagctgcag cctcaggttcctggccagcaaccagcacagcctccagcccaccagcagatgaggactctc aatgccctaggaaacaaccccatgagtatcccagcaggaggaataacaacagatcaacag ccaccaaacttgatttcagaatcagctcttccaacttccttgggggctaccaatccactg atgaatgatggttcaaactctggtaacattggaagcctcagcacgatacctacagcagcg cctccttccagcactggtgttcgaaaaggctggcatgaacatgtgactcaggacctacgg agtcatctagtccataaactcgttcaagccatcttcccaactccagaccctgcagctctg aaagatcgccgcatggagaacctggttgcctatgctaagaaagtggagggagacatgtat gagtctgctaatagcagggatgaatactatcatttattagcagagaaaatctataaaata caaaaagaactagaagaaaagcggaggtcacgtttacataagcaaggcatcctgggtaac cagccagctttaccagcttctggggctcagccccctgtgattccaccagcccagtctgta agacctccaaatgggcccctgcctttgccagtgaatcgcatgcaggtttctcaagggatg aattcatttaacccaatgtccctgggaaacgtccagttgccacaggcacccatgggacct cgtgcagcctcccctatgaaccactctgtgcagatgaacagcatggcctcagttccgggt atggccatttctccttcacggatgcctcagcctccaaatatgatgggcactcatgccaac aacattatggcccaggcacctactcagaaccagtttctgccacagaaccagtttccatca tccagtggggcaatgagtgtgaacagtgtgggcatggggcaaccagcagcccaggcaggt gtttcacagggtcaggtacctggagctgctctccctaaccctctgaacatgctggcaccc caggccagccagctgccttgcccaccagtgacacagtcaccattgcacccgactccacct cctgcttccacagctgctggcatgccctctctccaacatccaacggcaccaggaatgacc cctcctcagccagcagctcccactcagccatctactcctgtgtcatctgggcagactcct accccaactcctggctcagtgcccagcgctgcccaaacacagagtacccctacagtccag gcagcagcacaggctcaggtgactccacagcctcagaccccagtgcagccaccatctgtg gctactcctcagtcatcacagcagcaaccaacgcctgtgcatactcagcctcctggcaca ccgctttctcaggcagcagccagcattgataatagagtccctactccctcctctgtgacc agtgctgaaaccagttcccagcagccaggacccgatgtgcccatgctggaaatgaagaca gaggtgcagacagatgatgctgagcctgaacctactgaatccaagggggaacctcggtct gagatgatggaagaggatttacaaggttcttcccaagtaaaagaagagacagatacgaca gagcagaagtcagagccaatggaagtagaagaaaagaaacctgaagtaaaagtggaagct aaagaggaagaagagaacagttcgaacgacacagcctcacaatcaacatctccttcccag ccacgcaaaaaaatctttaaacccgaggagctacgccaggcacttatgccaactctagaa gcactctatcgacaggacccagagtctttgccttttcgtcagcctgtagatcctcagctc ctaggaatcccagattattttgatatagtgaagaatcctatggacctttctaccatcaaa cgaaagctggacacagggcaatatcaagaaccctggcagtatgtggatgatgtctggctt atgttcaacaatgcgtggctatataatcgtaaaacgtcccgtgtatataaattttgcagt aaacttgcagaggtctttgaacaagaaattgaccctgtcatgcagtctcttggatattgc tgtggacgaaagtatgagttctccccacagactttgtgctgttacggaaagcagctgtgt acaattcctcgtgatgcagcctactacagctatcagaataggtatcatttctgtgagaag tgtttcacagagatccagggcgagaatgtgaccctgggtgacgacccttcccaacctcag acgacaatttccaaggatcaatttgaaaagaagaaaaatgataccttagatcctgaacct tttgttgactgcaaagagtgtggccggaagatgcatcagatttgtgttctacactatgac atcatttggccttcaggttttgtgtgtgacaactgtttgaagaaaactggcagacctcgg aaagaaaacaaattcagtgctaagaggctgcagaccacacgattgggaaaccacttagaa gacagagtgaataagtttttgcggcgccagaatcaccctgaagctggggaggtttttgtc agagtggtggccagctcagacaagactgtggaggtcaagccgggaatgaagtcaaggttt gtggattctggagagatgtcggaatctttcccatatcgtaccaaagcactctttgctttt gaggagatcgatggagtcgatgtgtgcttttttgggatgcatgtgcaagaatacggctct gattgccccccaccaaatacaaggcgtgtatacatatcttatctggacagtattcatttc ttccggccccgctgcctccggacagctgtttaccatgagatcctcatcggatatctcgag tatgtgaagaaattggggtatgtgacaggacatatttgggcctgtcccccaagtgaagga gatgactatatctttcattgccacccccctgaccagaaaatccccaaaccaaaacgacta caggagtggtacaagaagatgctggacaaggcgtttgcagagaggatcattaacgactat aaggacatcttcaaacaagcgaacgaagacaggctcacgagtgccaaggagttgccctat tttgaaggagatttctggcctaatgtgttggaagaaagcattaaggaactagaacaagaa gaagaagaaaggaaaaaagaagagagtactgcagcgagtgagactcctgagggcagtcag ggtgacagcaaaaatgcgaagaaaaagaacaacaagaagaccaacaaaaacaaaagcagc attagccgcgccaacaagaagaagcccagcatgcccaatgtttccaacgacctgtcgcag aagctgtatgccaccatggagaagcacaaggaggtattctttgtgattcatctgcatgct gggcctgttatcagcactcagccccccatcgtggaccctgatcctctgcttagctgtgac ctcatggatgggcgagatgccttcctcaccctggccagagacaagcactgggaattctct tccttacgccgctccaaatggtccactctgtgcatgctggtggagctgcacacacagggc caggaccgctttgtttatacctgcaatgagtgcaaacaccatgtggaaacacgctggcac tgcactgtgtgtgaggactatgacctttgtatcaattgctacaacacaaagagccacacc cataagatggtgaagtgggggctaggcctagatgatgagggcagcagtcagggtgagcca cagtccaagagcccccaggaatcccggcgtctcagcatccagcgctgcatccagtccctg gtgcatgcctgccagtgtcgcaatgccaactgctcactgccgtcttgccagaagatgaag cgagtcgtgcagcacaccaagggctgcaagcgcaagactaatggaggatgcccagtgtgc aagcagctcattgctctttgctgctaccacgccaaacactgccaagaaaataaatgccct gtgcccttctgcctcaacatcaaacataagctccgccagcagcagatccagcatcgcctg cagcaggctcagctcatgcgccggcgaatggcaaccatgaacacccgcaatgtgcctcag cagagtttgccttctcctacctcagcaccacccgggactcctacacagcagcccagcaca ccccaaacaccacagcccccagcccagcctcagccttcacctgttaacatgtcaccagct ggcttccctaatgtagcccggactcagcccccaacaatagtgtctgctgggaagcctacc aaccaggtgccagctcccccaccccctgcccagcccccacctgcagcagtagaagcagcc cggcaaattgaacgtgaggcccagcagcagcagcacctataccgagcaaacatcaacaat ggcatgcccccaggacgtgcaggtatggggaccccaggaagccaaatgactcctgtgggc ctgaatgtgccccgtcccaaccaagtcagtgggcctgtcatgtctagtatgccacctggg cagtggcagcaggcacccatccctcagcagcagccgatgccaggcatgcccaggcctgta atgtccatgcaggcccaggcagcagtggctgggccacggatgcccaatgtgcagccacca aggagcatctcgccaagtgccctgcaagacctgctacggaccctaaagtcacccagctct cctcagcagcagcagcaggtgctgaacatccttaaatcaaacccacagctaatggcagct ttcatcaaacagcgcacagccaagtatgtggccaatcagcctggcatgcagccccagccc ggacttcaatcccagcctggtatgcagccccagcctggcatgcaccagcagcctagtttg caaaacctgaacgcaatgcaagctggtgtgccacggcctggtgtgcctccaccacaacca gcaatgggaggcctgaatccccagggacaagctctgaacatcatgaacccaggacacaac cccaacatgacaaacatgaatccacagtaccgagaaatggtgaggagacagctgctacag caccagcagcagcagcagcaacagcagcagcagcagcagcaacaacaaaatagtgccagc ttggccgggggcatggcgggacacagccagttccagcagccacaaggacctggaggttat gccccagccatgcagcagcaacgcatgcaacagcacctccccatccagggcagctccatg ggccagatggctgctccaatgggacaacttggccagatggggcagcctgggctaggggca gacagcacccctaatatccagcaggccctgcagcaacggattctgcagcagcagcagatg aagcaacaaattgggtcaccaggccagccgaaccccatgagcccccagcagcacatgctc tcaggacagccacaggcctcacatctccctggccagcagatcgccacatcccttagtaac caggtgcgatctccagcccctgtgcagtctccacggccccaatcccaacctccacattcc agcccgtcaccacggatacaaccccagccttcaccacaccatgtttcaccccagactggt tcccctcaccctggactcgcagtcaccatggccagctccatggatcagggacacctgggg aaccctgaacagagtgcaatgctcccccagctgaatacccccaacaggagcgcactgtcc agtgaactgtccctggttggtgataccacgggagacacactagaaaagtttgtggagggt ttgtag

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