Mus musculus (house mouse): 12978
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Entry
12978 CDS
T01002
Symbol
Csf1r, CD115, CSF-1R, Csfmr, Fim-2, Fim2, Fms, M-CSF-R, M-CSFR
Name
(RefSeq) colony stimulating factor 1 receptor
KO
K05090
macrophage colony-stimulating factor 1 receptor [EC:
2.7.10.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04010
MAPK signaling pathway
mmu04014
Ras signaling pathway
mmu04015
Rap1 signaling pathway
mmu04060
Cytokine-cytokine receptor interaction
mmu04061
Viral protein interaction with cytokine and cytokine receptor
mmu04151
PI3K-Akt signaling pathway
mmu04380
Osteoclast differentiation
mmu04640
Hematopoietic cell lineage
mmu05200
Pathways in cancer
mmu05202
Transcriptional misregulation in cancer
mmu05221
Acute myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
12978 (Csf1r)
04014 Ras signaling pathway
12978 (Csf1r)
04015 Rap1 signaling pathway
12978 (Csf1r)
04151 PI3K-Akt signaling pathway
12978 (Csf1r)
09133 Signaling molecules and interaction
04060 Cytokine-cytokine receptor interaction
12978 (Csf1r)
04061 Viral protein interaction with cytokine and cytokine receptor
12978 (Csf1r)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
12978 (Csf1r)
09158 Development and regeneration
04380 Osteoclast differentiation
12978 (Csf1r)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
12978 (Csf1r)
05202 Transcriptional misregulation in cancer
12978 (Csf1r)
09162 Cancer: specific types
05221 Acute myeloid leukemia
12978 (Csf1r)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
12978 (Csf1r)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mmu04090
]
12978 (Csf1r)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
12978 (Csf1r)
Protein kinases [BR:
mmu01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
12978 (Csf1r)
CD molecules [BR:
mmu04090
]
Proteins
12978 (Csf1r)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
Ig_2
I-set
ig
VEGFR-1-like_Ig-like
Ig_VEGFR-1-like_5th
Motif
Other DBs
NCBI-GeneID:
12978
NCBI-ProteinID:
NP_001032948
MGI:
1339758
Ensembl:
ENSMUSG00000024621
UniProt:
P09581
Q3UKC6
Q0P635
Q6NXV8
Structure
PDB
PDBj
LinkDB
All DBs
Position
18:61238644..61264211
Genome browser
AA seq
977 aa
AA seq
DB search
MELGPPLVLLLATVWHGQGAPVIEPSGPELVVEPGETVTLRCVSNGSVEWDGPISPYWTL
DPESPGSTLTTRNATFKNTGTYRCTELEDPMAGSTTIHLYVKDPAHSWNLLAQEVTVVEG
QEAVLPCLITDPALKDSVSLMREGGRQVLRKTVYFFSPWRGFIIRKAKVLDSNTYVCKTM
VNGRESTSTGIWLKVNRVHPEPPQIKLEPSKLVRIRGEAAQIVCSATNAEVGFNVILKRG
DTKLEIPLNSDFQDNYYKKVRALSLNAVDFQDAGIYSCVASNDVGTRTATMNFQVVESAY
LNLTSEQSLLQEVSVGDSLILTVHADAYPSIQHYNWTYLGPFFEDQRKLEFITQRAIYRY
TFKLFLNRVKASEAGQYFLMAQNKAGWNNLTFELTLRYPPEVSVTWMPVNGSDVLFCDVS
GYPQPSVTWMECRGHTDRCDEAQALQVWNDTHPEVLSQKPFDKVIIQSQLPIGTLKHNMT
YFCKTHNSVGNSSQYFRAVSLGQSKQLPDESLFTPVVVACMSVMSLLVLLLLLLLYKYKQ
KPKYQVRWKIIERYEGNSYTFIDPTQLPYNEKWEFPRNNLQFGKTLGAGAFGKVVEATAF
GLGKEDAVLKVAVKMLKSTAHADEKEALMSELKIMSHLGQHENIVNLLGACTHGGPVLVI
TEYCCYGDLLNFLRRKAEAMLGPSLSPGQDSEGDSSYKNIHLEKKYVRRDSGFSSQGVDT
YVEMRPVSTSSSDSFFKQDLDKEASRPLELWDLLHFSSQVAQGMAFLASKNCIHRDVAAR
NVLLTSGHVAKIGDFGLARDIMNDSNYVVKGNARLPVKWMAPESIFDCVYTVQSDVWSYG
ILLWEIFSLGLNPYPGILVNNKFYKLVKDGYQMAQPVFAPKNIYSIMQSCWDLEPTRRPT
FQQICFLLQEQARLERRDQDYANLPSSGGSSGSDSGGGSSGGSSSEPEEESSSEHLACCE
PGDIAQPLLQPNNYQFC
NT seq
2934 nt
NT seq
+upstream
nt +downstream
nt
atggagttggggcctcctctggtcctgctgctggccacagtttggcatggtcagggggcc
cctgtcatcgagcctagtggcccagaactggttgtagagccgggtgaaacggtgaccctg
cgatgtgtgagcaatggcagtgtggaatgggatggccccatctctccctactggaccttg
gaccctgaatctcccggaagcaccctgaccacaagaaacgcgaccttcaaaaacactggg
acctaccgttgtaccgagcttgaagaccccatggcaggcagtaccaccatccacttgtat
gtcaaagatccggcccactcttggaatttgctggcacaggaggtgacagtggttgagggc
caggaagctgtgctgccctgtctgatcactgaccctgcactgaaggacagtgtctcactg
atgcgtgaggggggcaggcaggtcttacgcaaaacggtctacttcttctcgccatggcga
gggttcattatccgcaaggctaaagtccttgacagcaatacctacgtgtgcaagaccatg
gtgaatggtagggaatccacctccactggcatctggcttaaggtgaatcgagtccaccca
gagcccccacagataaaattggagcctagcaagctggtgcggattcgaggggaggctgcg
cagatcgtgtgctcggccactaacgccgaagtgggattcaacgttatcctcaaacgtgga
gacaccaagctggaaatccccctaaacagtgacttccaagataactattataaaaaagtc
cgggctctcagtctcaacgctgtggacttccaagacgctggcatatattcttgtgtggcc
agcaatgatgttggcacacgcacggccaccatgaacttccaggtggtggagagtgcctac
ttaaacttgacctctgagcagagcctcttgcaggaggtgtctgtgggtgacagcctcatc
ctcacggtccatgcagatgcctaccctagcatacagcattacaactggacctacctaggt
ccattctttgaagaccagcgcaagcttgagtttatcacccaaagggccatatacaggtac
acattcaagctctttctgaaccgtgtaaaggcctcagaggcgggccagtacttcttaatg
gcacaaaacaaggcaggctggaataatctgacctttgagctcaccctgcgatatccccca
gaggtcagtgttacatggatgcctgtgaatggctctgatgtcctgttctgtgacgtctct
gggtaccctcagcccagcgtgacatggatggagtgcaggggccacaccgataggtgtgat
gaagcccaggctttgcaggtttggaatgacacccaccctgaagtcctgagtcagaagccc
ttcgacaaagtgatcattcagagccagctgcccattgggaccttaaaacacaacatgact
tatttttgcaaaacccacaacagtgtgggtaacagctctcagtacttcagggccgtctcc
ctaggacaaagcaagcagctccccgatgagtccctcttcactccggtggtggtggcctgt
atgtctgtcatgtctctgctggtgctactgctgttgctgctcttgtacaagtacaagcag
aagccgaagtaccaggtgcgctggaagatcatcgagagatacgaaggcaatagctacacc
ttcattgaccctactcagttgccctacaatgagaagtgggagttccctcggaacaacctg
cagtttggtaagactctaggagccggtgcctttgggaaggtggtggaggctacagccttt
ggtctgggcaaagaagatgcagtgctgaaggtggctgtgaagatgctaaagtccacggct
catgctgatgagaaggaggccctgatgtcagagctgaagatcatgagtcacctgggacag
cacgagaatatagtcaacctcttgggagcctgtactcacggaggacctgtcctggtcatc
actgaatactgctgctatggagacctactcaactttctccgaaggaaggccgaggctatg
ctaggacccagcctgagtcctggtcaggactccgagggagactccagctacaagaacatc
cacctggagaagaaatatgtgcgcagggacagtggcttctccagtcagggtgtagacacc
tacgtggagatgaggcctgtctcgacttcttcaagtgactccttctttaagcaagatctg
gacaaagaggccagccggcccctggagctctgggacctgctccacttctccagccaagtg
gctcagggcatggccttccttgcttctaaaaactgcatccaccgggacgtagcagctcga
aacgtgctgttgaccagcggacatgtggccaagattggggactttggactggctagggac
atcatgaatgactccaactatgttgtcaagggcaatgcccgcctgcctgtaaagtggatg
gccccagagagcatctttgactgcgtctacacagttcagagtgatgtgtggtcctacggc
atcctcctctgggagatcttctcgcttggtctgaacccctaccccggcatcctagtgaac
aacaagttctacaaactggtgaaggatggataccaaatggcccagcctgtatttgcaccg
aagaacatatacagcatcatgcagtcctgctgggacctggagcctaccagaagacccacc
ttccaacagatctgcttcctcctccaggagcaggcccgactggagaggagagaccaggac
tatgctaacctgccaagcagcggtggcagcagcggcagtgacagtggtggtggcagcagc
ggtggcagcagcagtgagccagaagaggagagctccagtgaacacctggcctgctgtgag
ccaggggacatcgcccagcccctgctgcagcctaacaactaccagttctgctga
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