Mus musculus (house mouse): 13417 Help Entry 13417             CDS       T01002                                  Symbol Dnah8, ATPase, Dnahc8, Hst6.7b, P1-Loop Name (RefSeq) dynein, axonemal, heavy chain 8   KO K10408   dynein axonemal heavy chain Organism mmu  Mus musculus (house mouse) Pathway mmu04814   Motor proteins mmu05014   Amyotrophic lateral sclerosis mmu05016   Huntington disease mmu05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:mmu00001]  09140 Cellular Processes   09142 Cell motility    04814 Motor proteins     13417 (Dnah8)  09160 Human Diseases   09164 Neurodegenerative disease    05014 Amyotrophic lateral sclerosis     13417 (Dnah8)    05016 Huntington disease     13417 (Dnah8)    05022 Pathways of neurodegeneration - multiple diseases     13417 (Dnah8)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    03037 Cilium and associated proteins [BR:mmu03037]     13417 (Dnah8)    04812 Cytoskeleton proteins [BR:mmu04812]     13417 (Dnah8) Cilium and associated proteins [BR:mmu03037]  Motile cilia and associated proteins   Dynein arm    13417 (Dnah8) Cytoskeleton proteins [BR:mmu04812]  Eukaryotic cytoskeleton proteins   Microtubules    Tubulin-binding proteins     Dyneins      13417 (Dnah8) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  DHC_N1 AAA_6 DHC_N2 Dynein_C AAA_8 AAA_9 AAA_7 AAA_lid_11 MT Dynein_heavy AAA_5 Dynein_AAA_lid AAA_lid_1 AAA_22 DYN_lid DYH2-5-8_CC AAA_16 Motif Other DBs NCBI-GeneID:  13417 NCBI-ProteinID:  NP_038839 MGI:  107714 Ensembl:  ENSMUSG00000033826 UniProt:  Q91XQ0 LinkDB All DBs Position 17:30845909..31094736 Genome browser AA seq 4731 aa AA seqDB search MESEEGNAEPPPPSEEAPPPVVEEAPPPLPPEDTAPPPPEEQAPPPEGDAAPPPTGDAFQ LTVEGEAPHPEDPKLLSEQGPATSVTDYRSLIPSDEEVTLPEDEESGQARVRARHTPRPA QSVLSDGISQSSRRPSKFRRSMTGIPNLQETLKEKQARFREARENRKMKIGPSHKYIFEV LGEKLGLDLVTVEELILDCPSLDPFTSFFEKGGCKTLKFLYQEGEVPGFECGRTITGVPK GGKMMRIYVDNAAPDKLKGLCLFFVRCRNDVAINSKTIHEDVLFSFLDASKGLLEGIKHM LKSIFLPAILATSNWGALNQSKQGESEKHIFIETIHRYLASLDDATISIEGTVMLKKVDN IDFSKLHTFEEVTAAASSSEMVHQLEEVLMVWYKQIEQVLIESEQMRKEADDSGPLTELE HWKRMSAKFNFIIEQIKGSNCKAVINVLNVAHSKLLKNWRDLDARITDSANESKDNVRYL YTLEKVCQPLYNYDLVSMAHGIQNLINAIRMIHSVSRYYNTSERMTSLFIKVTNQMVTAC KAYITDGGTNHVWDQETPAVLKKIQDCIFLFKEYQASFHKTRKQILESSGEKSFEVSEMY IFGKFEAFCKRLEKITEMITIVQTYSALSNSTIEGIDILGIKFKNIYQGIKKNQYDILDP RRTEFDTDFTEFMGKINILEIQIQAFMNSTFGKILSSQQALQLLQRFQKLNIPCLHLEIN HTIERILQCYVAELEFTKKLYLSQKDDPPLARNMPPIAGKILWVRQLFRRINEPINYFFK NSDILSSTEGKAVIRQYNRIAYVLVEFEVAYHTAWFKEVSQLQYALQATLFVRHPETGKL LVNFDPKILEVVRETKCMIKMKLDVPEQAKNLLKLESKLKADKLYLQGLLQYYDDLCQEV PSVFVNLMTPKMKKVESVLRQGLTVLTWSSLMLESFFKEVESVLDMFNQLLKKVNDLCEM HIDTVLKEIAKTLLISLSDSGTTKVEDMLTLNETYTKECADILNHKSRHVEEAVKELILI FEQIYEVKYTGKAAKSVKEQRKRVVFGSEAEETEGLDFESTTMEVDTNDKEDEFKKECKE VYAFFSHQLLDSLQKATRLSLDTMKRRIFVGSQGRRRSEDIVSFIKTEVHLAIPNVVMVP SLDDIQQAINRMIQLTLEVSRGVAHWGQQQVRQIKSFQNNSRGSDQPPASGKPLKKEERS FEETIPARKLKNFYPGVAEHKDISKLVLLLSSSVNSLRKAATEALQDFQKYKTLWIEDRH VKVKEFLANNPSLTEIRSEILHYATLEQEIKELKPIIVVGSLELHTEPMKLALSIEAKAW KMLLCRYLNEEYKKKMSDMITFINEYLKKLSRPIRDLDDVRFAMEALSCIRDNEIQMDMT LGPIEEAYGILNRFEVKVTKEESEGVDTLRYSFNKLQSKAVSVQGELVKVQPKFKSNLLE SVKVFCEDVINFTEAYETEGPMVPNIPPQEASNRLQIFQANFDDLWRKFVTYSSGEQLFG LPVTDYEVLHKTRKELNLLQKLYGLYDTVMGSISGYYEILWGDVDIEKINAELQEFQNRC RKLPRALKDWQAFLDLKKRIDDFSESCPLLEMMTNKAMKQRHWDRISELTGTPFDVESDT FCLRNIMEAPLLKNKDDIEDICISAIKEKDIEAKLTQVIENWTYQNLSFAAFKGKGELLL KGTESGEIITLMEDSLMVLGSLLSNRYNTPFKKNIQNWVFKLSTSSDIIEEWLIVQNLWV YLEAVFVGGDIAKQLPQEAKRFQNIDKSWIKIMQRAHENPNVISCCVGDETMGQLLPHLH EQLEVCQKSLTGYLEKKRLLFPRFFFVSDPVLLEILGQASDSHTIQPHLPAVSDNINEVT FHAKDYDRMTAVISREGEKIMLDTPVMAKGPVEIWLLDLLKVQMSSLHNIIRSAFYQISD SGFLLLPFLNHFPAQVGLLGIQMLWTHDSEEALNNAKDDRKIMQITNQKFLDILNTLISQ TTHDLTKFDRVKFETLITIHVHQRDIFDDLVKMHIKSVTDFEWLKQSRFYFKEDLDQTVV SITDVDFIYQNEFLGCTDRLVITPLTDRCYITLAQALGMNMGGAPAGPAGTGKTETTKDM GRCLGKYVVVFNCSDQMDFRGLGRIFKGLAQSGSWGCFDEFNRIELPVLSVAAQQIYIVL TARKERKKQFIFSDGDCVDLNPEFGIFLTMNPGYAGRQELPENLKIQFRTVAMMVPDRQI IMRVKLASCGFLENVILAQKFYVLYKLCEEQLTKQVHYDFGLRNILSVLRTLGSQKRARP EDSELSTVMRGLRDMNLSKLVDEDEPLFLSLINDLFPGLQLDSSTYAELQSAVDNQVNLE GLINHPPWNLKLVQLYETSLVRHGLMTLGPSGSGKTTVITILMKSLTECGRPHREMRMNP KAITAPQMFGRLDTATNDWTDGIFSTLWRKTLKAKKGENIFLILDGPVDAIWIENLNSVL DDNKTLTLANGDRIPMAPTCKLLFEVHNIENASPATVSRMGMVYISSSALSWRPILQAWL KKRSQQEASVFLSLYDKVFEDAYTYMKLSLNPKMQLLECNYIMQSLNLLEGLIPSKEEGG VSSGDHLHKLFVFGLMWSLGALLELDSREKLEVFLRGHGSKLNLPEIPKGSQQTMYEFYV TDYGDWEHWNKRIQPYFYPTDSIPEYSSILVPNVDNIRTNFLIDTIAKQHKAVLLTGEQG TAKTVMVKAYLKKYDPEVQLSKSLNFSSATEPMMFQRTIESYVDKRMGSTYGPPGGRKMT VFIDDINMPVINEWGDQITNEIVRQMMEMEGMYSLDKPGDFTTIVDVQLIAAMIHPGGGR NDIPQRLKRQFTVFNCTLPSNTSIDKIFGIIGCGYFDPCRKFRPEICDMVGNLVSVSRVL WQWTKVKMLPTPSKFHYIFNLRDLSRIWQGMLTVKAEECSSIPILLSLFKHECNRVIADR FITPDDEQWFNSQLIRAVEENISPEVAANILPEPYFVDFLRDMPEPTGDEPEDTMFEVPK IYELVPSFEFLSEKLQFYQRQFNEIIRGTSLDLVFFKDAMTHLVKISRIIRTSCGNALLV GVGGSGKQSLSKLASFIAGYQIFQITLTRSYNVSNLIEDLKNLYKVAGAEGKGITFIFTD NEIKDEAFLEYLNNLLSSGEISNLFARDEMDEITQGLISVMKRELPRHPPTFDNLYEYFI TRSRKNLHVVLCFSPVGEKFRARSLKFPGLISGCTMDWFSRWPKEALIAVASYFLLDYNI VCSIETKRHVVETMGLFHDMVSESCENYFQRYRRRAHVTPKSYLSFINGYKSIYTDKVKY INEQAERMNIGLDKLMEASESVAKLSQDLAVKEKELAVASIKADEVLAEVTVSAQASAKV KNEVQEVKDKAQKIVDEIDSEKVKAETKLEAAKPALEEAEAALNTIKPNDIATVRKLAKP PHLIMRIMDCVLLLFQKKIDPVTMDPEKPCCKPSWGESLKLMSATGFLFSLQQFPKDTIN EETVELLQPYFNMDDYTFESAKKVCGNVAGLLSWTLAMVIFYGINREVLPLKANLAKQEG RLAVANVELGKAQALLDEKQAELDKVQAKFDAAMKEKMDLLNDADMCRKKMQAASTLIDG LSGEKVRWTQQSKEFKTQINRLVGDVLLCTGFLSYLGPFNQIFRNYLLKDQWELELKARK IPFTENLNLIAMLVDPPTIGEWGLQGLPGDDLSIQNGIIVTKATRYPLLIDPQTQGKTWI KSKEKENDLQVTSLNHKYFRTHLEDSLSLGRPLLIEDIREELDPALDNVLEKNFIKSGTA FKVKVGDKECDIMDTFKLYITTKLPNPAFTPEINAKTSVIDFTVTMKGLENQLLRRVILT EKQELESERVKLLEDVTFNKRKMKELEDNLLYKLSATKGSLVDDESLIGVLRITKQTAAE VSEKLHVAAETEIKINTAQEEFRPAATRGSILYFLITEMSMVNIMYQTSLAQFLKLFDQS MARSEKSPLPQKRITNIIEYLTYEVFTYSVRGLYENHKFLFVLLMTLKIDLQRGTVKHKE FQALIKGGAALDLKACPPKPFRWILDMTWLNLVELSKLPQFAEIMNQISRNEKGWKNWFD KDAPEEEIIPDGYNDSLDTCRKLLLIRSWCPDRTVFQARKYIADSLEEKYTEPVILNLEK TWEESDTHTPLICFLSMGSDPTIQIDALAKKLKLECRTISMGQGQEVHARKLIQLSMQQG GWVLLQNCHLGLEFMEELLEMLMVTETTEDSFRVWITTEPHDRFPITLLQTSIKFTNEPP QGVRAGLKRTFAGINQDLLDISNLPMWKPMLYTVAFLHSTVQERRKFGPLGWNIPYEFNS ADFSASVQFIQNHLDECDIKKGVSWSTVRYMIGEVQYGGRVTDDFDKRLLNCFARVWFSE KMFEPSFCFYTGYKIPICKTLDQYFEFIQSLPSLDNPEVFGLHPNADITYQSNTASDVLE TITNIQPKESGGGVGETREAIVYRLSEDMLSKLPPNYVPHEVKARLMKMGHLNSMNIFLR QEIDRMQKVISILRSSLSDLKLAIEGTIIMSENLRDALDNMYDARIPQLWKRVSWDSSTL GFWFTELLERNAQFSTWIFEGRPNVFWMTGFFNPQGFLTAMRQEVTRAHKGWALDTVTIH NEVLRQTKEEIITPPAEGVYIYGLYMDGASWDRRNGKLTESTPKVLFTQLPVLHIFAINS TAPKDPKLYVCPIYKKPRRTDLTFITVVYLRTVLSPDHWILRGVALLCDIK NT seq 14196 nt NT seq  +upstreamnt  +downstreamnt atggagtctgaggaaggcaacgcagagccaccccctccgagtgaagaggctcctcctcca gttgtagaggaagctccgccccctctccctccagaagacactgcccctccccctcccgag gagcaggccccgccccctgagggggatgctgccccgccccccacaggagatgccttccaa ctcactgtggaaggagaagctccgcaccccgaggatcccaagctcctgtctgagcagggt cctgctacttccgtgactgactataggagtctgattccctcagatgaggaggtaacactg ccggaggatgaggagtctggccaggccagggtccgggcgaggcacacccctaggcctgca cagtcggtgctgtcagacgggatttcgcagtcttcccggcggccctctaagttccgccga agtatgactggcatcccaaacctccaggagaccctcaaagagaaacaggcaagatttaga gaagcaagggaaaaccggaaaatgaaaattggcccctcgcataaatacatatttgaagtt ctaggagaaaagcttgggttggacttagtaactgtggaagaactaattttggattgcccg tcgctggatccgttcaccagcttttttgagaaaggtggctgtaagacgctgaagtttttg taccaggaaggagaagtgcccggttttgaatgtggtcgaacgattacgggagtccccaaa ggggggaaaatgatgaggatttatgtagacaacgcagctccggacaagctgaaagggctg tgcttatttttcgtccgttgtcgtaatgatgttgccataaattccaaaaccattcatgag gatgtgctgtttagcttcttggatgcatcaaaaggactcctagaaggaatcaagcacatg ttgaaaagcatatttctcccagccatccttgcaactagcaactggggagctttaaaccag tccaagcagggtgaatctgagaaacatattttcatagaaaccatccacagatatcttgca tctttagatgatgctaccataagcatcgaggggacagtgatgttgaagaaggtggacaat atcgacttctccaagctgcacacctttgaagaggtcacagctgcagcaagcagctcggag atggtgcatcagctggaggaggtgctgatggtgtggtacaagcagatcgagcaggtcctc attgagagtgagcagatgagaaaagaagctgatgattccggtcccctcaccgaattggag cattggaagcgtatgtcagccaagttcaacttcatcattgagcagattaaagggtccaac tgtaaggccgtcataaatgtgctaaatgtcgcacactccaagctgttaaagaactggcgg gatttggacgcacgaatcaccgactccgctaatgaatcaaaggataacgtgcgctatttg tacaccctggagaaagtgtgtcagcccctctataactacgacctggtttccatggcacac gggatacagaacctgatcaatgccatcagaatgattcacagtgtgtcgaggtattataat acatcagagaggatgacgtcattattcatcaaggtgacaaatcagatggtaacagcctgc aaagcatacattactgacggcggaacaaaccatgtgtgggaccaggaaacgccagctgta ctaaaaaaaatccaggattgcatctttctcttcaaggaataccaggcatcctttcacaaa acaaggaagcagattttagaatcctctggggagaagtcttttgaagtttcagaaatgtat atatttggaaaattcgaagccttctgtaagagactggagaaaattacagagatgataacc attgtgcagacatactcagccttgagcaactctacaatcgaaggaatcgatatcctgggg ataaagttcaaaaacatctaccagggcattaagaagaaccaatatgacatcctggatcca cggagaacagaatttgacacagacttcacagagtttatggggaaaatcaatattttagag attcaaatccaggcgtttatgaacagcacctttggaaagatcttgtcctcccagcaggct ctgcagctgcttcagaggtttcagaagctgaacatcccctgccttcacctggaaatcaat cacacaattgaacggattcttcagtgctatgtggctgaacttgaatttaccaagaagctc tatctttctcagaaagatgacccccctctcgctcgcaacatgccccccatagcagggaaa attctctgggtgaggcagctgttccgccggataaatgaacccatcaactatttctttaaa aactcagacattttatcaagcacagaaggcaaagctgtcatccgtcagtataataggatc gcgtacgtgctggtggagtttgaggtggcttaccacacagcctggttcaaggaggtttcc cagcttcagtatgctttgcaagccacgctgtttgtgcgacatccggaaacggggaagttg ctggttaactttgatcctaagattctggaagttgtgcgggaaacgaaatgcatgataaag atgaagctggacgttccggaacaagcaaagaatttgctgaaactggagagcaaactgaag gcagacaagctgtatctgcagggtcttctgcagtattatgatgacctgtgccaggaagtg ccttctgtgttcgtcaacctgatgacccccaaaatgaagaaggtggagtccgtcctgagg caagggctcacagtgctgacctggtcctcgctaatgctggagagcttcttcaaagaggtt gagtccgttttggatatgttcaaccagcttttaaagaaggtcaatgacctgtgtgagatg cacatcgacacagttctgaaggagattgccaagacattgctaatctccttgtcagatagc ggcaccaccaaagtagaagacatgctgaccctcaacgagacgtacaccaaagagtgtgct gatattctaaaccacaagagcagacatgtggaggaagccgtgaaagagctgatattaata tttgaacaaatctacgaagttaaatacaccggaaaagcagccaaatcggtgaaagagcag aggaagcgcgttgtctttggaagtgaggcagaagagaccgaaggcctcgactttgaatcg acgacgatggaggtcgacaccaatgataaagaagatgaatttaaaaaggaatgtaaggag gtatacgctttcttctcgcatcaattactagacagcctacagaaggcgacgcgcttatct ttggacacaatgaaaaggagaatatttgtcggaagccaagggcggaggcggtcagaggac atcgtttccttcataaaaactgaagtgcaccttgcaatccctaatgtggtgatggttccc agcctggatgacattcagcaagccatcaatcgcatgatccagttgaccctggaggtcagc agaggagttgcccactggggacagcagcaggtcaggcagataaagtctttccagaacaat tctcgtggctccgaccaacccccagcctcggggaaaccactgaaaaaggaagagaggtct tttgaagaaaccatcccagccaggaagctgaagaacttctatcctggcgtggcagagcac aaggatatctccaagctggtgctcctcctgtcctcctctgtgaattctctccggaaggcg gccactgaggccctgcaggactttcagaagtacaagactctctggatcgaagaccgccac gtgaaagtcaaggagtttttggccaacaacccttccctgactgagatccgatcagaaatc ctccactatgccacccttgagcaagagatcaaggaactgaagcccattattgttgtagga tccctggaactgcacacagagccaatgaagttagccttatcgatcgaggccaaagcgtgg aagatgctgctctgtcgctacttaaatgaagaatataagaagaaaatgtcagacatgata acgtttatcaacgaatacttgaaaaagttgtccagacccatccgagacttggacgatgtc agattcgctatggaagctttgtcttgtattcgagataatgaaattcaaatggacatgact ttggggccaattgaagaagcctacggcattttgaacagatttgaggtcaaagtgaccaag gaagagtccgaaggcgttgacaccctgagatactcattcaacaaattacagagcaaagct gtttccgtacaaggtgaacttgtgaaagtgcagcccaaatttaaaagcaacctgctcgag tcggtgaaggtcttctgtgaggacgttataaactttacagaagcctatgagacggaagga cccatggtaccaaatattccaccccaagaggctagcaacaggctgcagatattccaggcc aatttcgacgatttatggaggaaatttgtcacatattcatccggggagcaactttttgga ttacctgtgactgactacgaggttttacacaaaaccagaaaagagctcaacttgcttcag aagctgtatggcttgtacgacactgtcatgggcagcatcagtggctactatgagatcctc tggggagatgtagacatcgaaaagatcaatgcagagctgcaggaattccagaacagatgt cgaaaactccccagggcactcaaagattggcaggcgtttctggacctcaaaaaaagaatc gacgactttagtgagtcgtgtccgctgctggagatgatgaccaataaagcgatgaagcag aggcattgggaccgcatctcagagctcaccggcaccccgttcgatgtggaatcggataca ttctgtctgagaaatatcatggaagcgccactccttaagaacaaggatgatatcgaagat atctgcatatctgccattaaggagaaggacatcgaagccaagctgacacaggtgattgag aactggacctaccaaaacctgagttttgcagcgtttaagggcaaaggcgagctcctgctc aaaggaacagagtctggagagattatcaccttaatggaggatagcttgatggtcctaggc tccttgctaagcaacagatacaataccccgtttaaaaaaaatatccagaattgggtcttt aaattgtccacttcctcggatatcattgaagagtggctgatagtccagaacctgtgggtc tatcttgaagctgtctttgtgggtggcgacattgccaaacagctgccgcaggaagccaag cgtttccagaatattgacaagtcatggataaagatcatgcagcgagctcatgagaacccc aacgtgatcagctgctgtgtcggggatgagaccatggggcagctcctgccccatttacac gagcagttggaagtctgtcagaagtccctcacagggtatttggaaaagaagaggttgcta tttccaagattcttctttgtctccgatccggttctgctggaaatcctcggacaggccagc gactcccacaccattcagccacatctccctgcagtgtctgacaacatcaatgaggtgacc ttccatgctaaagactacgatcggatgacggccgttatatcaagagaaggagaaaaaatc atgctggatactcccgttatggccaaagggcctgtagaaatttggcttctggacttgtta aaagtacagatgtcatcactccataatatcatccggtctgccttctaccagatcagcgat tcgggctttctcctcctacctttcctgaaccacttcccagcacaggttgggcttctggga attcaaatgttatggacacatgactcagaagaggctttgaataatgcaaaagacgacagg aaaatcatgcaaataaccaaccagaaatttttggacattctaaacacgctgattagccag acgacgcatgacctgaccaagtttgacagagtgaagtttgaaactttgatcacaatccat gtgcaccagagagatatctttgatgacttggtaaaaatgcacatcaagtcggtcaccgac ttcgagtggctgaaacagagcagattttatttcaaagaggatttggatcagaccgtggtg tccatcaccgatgtggacttcatttaccaaaacgagttcctgggatgcacggatcgcctt gtgatcaccccgttaacagatagatgctacatcacgctggctcaggctctgggaatgaac atgggcggtgctccagcaggacccgccgggacgggtaaaaccgaaaccacaaaagacatg ggcaggtgtttgggcaagtatgtggttgtgttcaattgttccgatcagatggatttccga ggcctcggacggattttcaaaggtcttgcacagtccggttcctggggttgctttgatgag tttaacagaattgaattgcccgttttatctgtggcggcgcaacaaatttacatagttttg acagcgaggaaagagaggaaaaaacagttcatcttctcagatggcgattgtgtggattta aatccagaattcggaatcttcctaaccatgaaccctggatatgccgggcgccaggaactg ccagaaaacttaaaaatccagtttagaacagttgcaatgatggttcctgatcggcagatc attatgcgagttaagcttgctagctgtggctttcttgaaaatgttatcttggcgcagaag ttttatgttctctataaactctgcgaagagcagcttactaaacaggtccactatgacttt ggactgagaaatatcctgtctgtgctgaggacccttgggtctcagaaaagagctcggcca gaagacagtgagttaagcacggtcatgagagggctacgagacatgaacctttctaaactg gttgacgaagatgagcctctgttcctcagcttgatcaacgacctgtttccggggttacaa ctggacagcagtacttacgcggaactgcaatccgcggtggacaaccaggttaacctagaa ggtctgataaaccacccaccctggaacctcaaattagtgcagttatatgagacctctctg gtacggcatggcctgatgaccctcgggcccagcggttctgggaagacgacggtcataaca attctgatgaaatcattaacggagtgtgggaggcctcacagagagatgcgaatgaatcca aaggcgattaccgcgcctcagatgttcggcaggctggatacagccaccaacgactggaca gatgggatcttttccactctgtggaggaagacattaaaagctaaaaagggtgagaacatc ttcctcatcctagacggccccgtggatgccatctggattgagaacttaaactccgtgttg gacgataacaagacgctcaccctggctaacggggaccgcatccccatggcccctacctgt aagctgctgtttgaggtgcacaacattgagaacgcctctcctgccacggtgtcaaggatg ggcatggtatacatcagcagctcggctctcagctggaggccgatattacaggcatggttg aagaagcgcagccagcaggaagcctccgtcttcctgagtctgtatgataaggtgtttgaa gacgcatacacgtacatgaaactaagcctcaaccccaagatgcagctcctggagtgtaat tacatcatgcagtctctcaatctcctggaaggtttaatcccttccaaagaagaaggtggc gtctcgtcgggggaccacctccacaagctgtttgtgtttggtctgatgtggagcctggga gcccttttggaactggatagcagggaaaaactggaagtcttcctccgaggtcacgggagc aagctgaacctgccggagatacccaagggctcccagcagactatgtatgagttttacgtt accgactacggtgactgggagcactggaacaagagaattcagccatacttctatccgacg gacagcattccagagtactcttccatcttggttccaaatgtggacaacatcaggaccaac ttcttgatagacacgatcgcgaaacagcacaaagcggttttgctcacgggagaacagggc acggcaaaaacggtaatggtgaaggcgtacctgaagaaatacgaccctgaagtgcagctg tccaagagtctgaatttttcctctgctacagagccaatgatgtttcagaggacaatcgaa agctacgtggataagaggatggggagtacctacggccccccaggagggaggaagatgacg gtgtttattgatgatattaatatgcccgtgatcaacgaatggggagatcagatcaccaat gagatcgtgcgtcagatgatggagatggagggaatgtacagcttggacaagcctggagac ttcaccaccattgtcgatgtgcagctcatagcagccatgatccatcctggaggagggcgg aacgacatcccacagcgcttaaaaaggcagtttaccgtgttcaactgcacgctgccttcc aacacgtctattgacaaaatcttcggaattatcggctgtggatactttgacccgtgtaga aagttcagacccgaaatatgtgacatggttgggaatttggtctcagtcagccgcgtactg tggcagtggacaaaggtaaagatgctacccacgccttcaaagtttcattacatcttcaac ctccgggacctttcgagaatctggcaggggatgttaaccgtaaaagcagaagagtgcagc tcgatccccattctcctgtcgctcttcaagcacgagtgtaacagagtgatcgcagacagg tttataactccggatgacgagcagtggttcaactcacagctcattcgggcggtggaagaa aacatcagcccagaggtcgcagccaatatcctccctgaaccatactttgtggattttctc cgagatatgccggagcccactggtgacgaacccgaagacactatgtttgaagtgcccaaa atctacgaattggtgccgtccttcgaattcctgagtgaaaagcttcagttctaccagagg caattcaacgagatcatccgagggacgtctctcgacctggtgttttttaaagacgccatg actcacctcgttaagatctctcggatcattcgaacctcctgtgggaacgcattgctggtg ggtgtcggtggctcaggaaagcagagcctctcaaaactggcctcctttattgctgggtat cagatatttcagataacactaaccaggtcttacaacgtaagcaacctcatagaagaccta aagaatttgtacaaagttgctggcgcggaaggcaaaggcatcaccttcatctttacggac aatgagataaaagatgaggcgttcctggaataccttaataatctgctgtcttcaggggag atctccaatttatttgcccgagacgagatggatgaaatcacccaaggcctgatatcggtg atgaagagggagctgcctcgacaccctcccacctttgacaacctgtatgaatacttcatc accagatccaggaagaatttacatgttgttctctgcttctccccggttggagagaagttc cgggcccggtccctcaaattccctggcttgatttcagggtgcaccatggactggttcagt cgctggcccaaggaggctctaatcgctgtggcctcatacttccttttagattataacatt gtctgctccattgagactaagaggcatgttgtagaaactatggggctctttcatgacatg gtttctgaaagctgcgagaattacttccaaagataccgccgaagagcccacgtgactccc aaatcatatctctcatttataaatggttataaaagcatttacaccgataaggtgaaatat atcaatgaacaagcggaacggatgaatatcggtctcgacaagctgatggaggcgagcgaa tctgtggctaagctctcacaggatctcgcagtgaaggagaaggaactggcggtggcttcc attaaagcagacgaagtcctggcagaggtcacagtgagtgcccaggcttcagccaaagtg aaaaacgaagtccaggaagtaaaagataaagctcagaaaattgtggatgaaattgacagc gagaaggtgaaagcagagactaagctggaggccgccaaacctgccctggaagaagcagaa gcagccctgaataccatcaaaccaaatgacattgccacagtcaggaagcttgccaaacca ccacatctcattatgagaatcatggactgtgtcctgttgctgttccaaaagaaaatcgat cctgttaccatggacccagaaaagccctgctgcaagccatcatggggagagtcgttaaag ctgatgagcgccaccgggttcctgttcagcctgcagcagttccccaaggacacaatcaac gaggaaactgttgaactactgcagccatattttaacatggacgactacacttttgaaagt gccaaaaaagtgtgtggcaacgtggctgggctgctttcctggacacttgctatggtgata ttttacggcatcaacagggaagtgttgcccttgaaggcaaacctggccaagcaggaaggc cgcttggctgtggccaatgtggaattagggaaggcccaggcgctgctggacgagaagcag gctgagctggataaagtgcaggccaagtttgacgccgcgatgaaggagaaaatggacctg ctcaatgatgccgacatgtgcaggaagaagatgcaggcagcctccacgctcattgatggc ctgagtggggagaaagtccggtggacccagcaaagtaaggagttcaagacgcagattaat agactcgtaggcgatgttctgctctgcacaggctttctctcctacctcggccccttcaat cagatatttcggaactatttgcttaaagaccaatgggagttagagttgaaagcacggaaa attcctttcactgaaaacctgaatcttattgcaatgttggtggaccctccaacaattggc gagtggggcctgcagggactccctggagatgacttgtcaattcagaatggcatcattgtg acaaaggccaccagataccctctgctcattgatccccagactcagggaaaaacgtggatc aaatcgaaggaaaaagaaaacgacttgcaggtgacatctctgaaccacaaatatttccgc acacacctggaggacagcctctcgttgggtcgcccccttctcatcgaggatattcgagag gagctggacccagctctggataatgtgctggagaagaactttatcaaatcaggcactgct ttcaaggtgaaagtgggtgacaaggaatgtgacatcatggacacgtttaaactttacatc accacgaagttaccaaaccctgccttcacccctgagatcaacgccaagacgtccgtcatt gatttcactgtcaccatgaagggactcgagaaccagttactcaggagagtcattctcaca gagaaacaggagctggagtcggagagggtgaagctcctcgaggacgtgactttcaataag cggaagatgaaggagctggaagacaacctgctatataagctgagcgccacaaaaggttcc ctggtggacgacgagtctctcatcggcgtcctgcgcatcaccaaacagacagctgcggaa gtgagcgaaaagctccacgtggctgcggaaacggagatcaagatcaatacagctcaggag gagttccggccagcggccacgcgaggcagcatcctttacttcctcatcacagagatgagc atggtcaacatcatgtaccaaacctccctggcccagttcttgaagttatttgaccagtcc atggccaggtctgaaaagtctccgctacctcaaaaaagaattacaaacattattgagtac ctgacatacgaggtcttcacctattctgtgagaggcctgtacgaaaaccacaaattcctc ttcgttctcctcatgacactgaagatcgatctccagagagggacagtgaagcacaaagag tttcaggctctgattaaaggtggagcagccctggacctgaaggcatgcccccccaagccc ttccgctggatcctggacatgacgtggctgaaccttgtggagctcagtaagctcccccag tttgcagaaattatgaaccagatatctcggaacgagaaggggtggaaaaactggtttgat aaagacgccccagaggaagagatcatccctgatggctataatgactccctggatacctgc cgcaagcttctgcttatcagatcatggtgccctgaccgcactgttttccaagcgagaaag tatatcgcggactctctcgaggagaagtacacggagccagttatcctaaatctggagaag acctgggaagaaagtgacacgcacacacctctgatctgtttcctgtccatgggctccgac cccaccatccagattgatgcgttggccaagaagctgaagctggaatgcaggactatctca atgggacaaggacaagaagttcatgctcgaaagctgatccagttgtccatgcaacagggt ggttgggtgttactgcagaattgtcacctcggtctagaattcatggaagagttactagag atgttgatggtcacagaaaccaccgaagactccttcagagtgtggataaccactgagccc catgatcggtttccaattacactactccagacttctatcaagttcacaaatgagccaccc caaggtgtccgggcaggcctgaaaaggacattcgctgggatcaaccaagaccttctggac atcagtaacttacccatgtggaagccgatgctgtacacggtggcatttctgcactccacc gtgcaggagcgacgaaaatttggacccttgggatggaatattccctatgaattcaattct gccgacttctcggccagcgttcagtttattcagaaccacctcgatgagtgtgatattaaa aagggtgtgtcgtggagtacagttcggtacatgattggtgaagtacagtacggaggcaga gtgacagatgacttcgacaaaaggctgcttaactgctttgcccgggtctggttcagtgag aagatgtttgagccctcgttctgtttttacaccggctacaaaatccccatatgcaaaacc ctggaccagtattttgagttcatccagtctctgccatccctcgataacccagaagtcttt gggcttcaccccaatgccgacatcacgtatcagagtaacacagcttccgacgttcttgaa accatcaccaacattcaaccgaaagagagcggtggtggtgtgggcgagacgcgcgaggcc attgtctacaggctgtctgaggacatgctcagcaagctgccccctaactatgtgcctcat gaggtgaaagctcgcttgatgaagatggggcacctgaactcaatgaacatatttcttaga caggaaattgacaggatgcagaaagtcatctcaatcctccgcagcagcctgagtgaccta aaactggctatcgaagggacgatcatcatgagtgagaacttgagagatgcgttggataac atgtatgatgctcgtatacctcagctttggaagagggtgtcctgggactcctccaccctg ggcttctggttcaccgaacttctggaaaggaacgcccagttctcgacatggatatttgag gggaggcctaacgtgttctggatgaccgggttctttaacccccaaggcttcctcacagca atgaggcaagaagtgacccgagctcacaaaggctgggcgctggacactgtgaccatccac aatgaagtcctgcggcagaccaaggaagagatcatcacgcccccagcggaaggcgtgtat atttacgggctgtatatggatggagcatcctgggacaggcggaacgggaagctcacagaa tccaccccgaaggttctcttcacgcagcttcctgttctgcatatttttgccattaactcc acggcgcccaaggatccgaagctgtacgtgtgtcctatctacaagaaacccaggcggact gacctcaccttcatcaccgtggtgtacctgcgcacggtgctgtccccggatcactggatc ctgagaggggtggccctcttgtgtgacatcaagtaa

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