Mus musculus (house mouse): 13433
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Entry
13433 CDS
T01002
Symbol
Dnmt1, Cxxc9, Dnmt, Dnmt1o, MCMT, MTase, Met-1, Met1, MommeD2, m.MmuI
Name
(RefSeq) DNA methyltransferase 1
KO
K00558
DNA (cytosine-5)-methyltransferase 1 [EC:
2.1.1.37
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00270
Cysteine and methionine metabolism
mmu01100
Metabolic pathways
mmu05206
MicroRNAs in cancer
Module
mmu_M00035
Methionine degradation
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
13433 (Dnmt1)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
13433 (Dnmt1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
mmu03000
]
13433 (Dnmt1)
03032 DNA replication proteins [BR:
mmu03032
]
13433 (Dnmt1)
03036 Chromosome and associated proteins [BR:
mmu03036
]
13433 (Dnmt1)
09183 Protein families: signaling and cellular processes
02048 Prokaryotic defense system [BR:
mmu02048
]
13433 (Dnmt1)
Enzymes [BR:
mmu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.37 DNA (cytosine-5-)-methyltransferase
13433 (Dnmt1)
Transcription factors [BR:
mmu03000
]
Eukaryotic type
Zinc finger
CXXC CpG-binding proteins
13433 (Dnmt1)
DNA replication proteins [BR:
mmu03032
]
Eukaryotic type
DNA Replication Termination Factors
DNA methylation enzymes
13433 (Dnmt1)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Heterochromatin formation proteins
Other heterochromatin formation proteins
13433 (Dnmt1)
Prokaryotic defense system [BR:
mmu02048
]
Restriction and modification system (R-M system)
Type II R-M system
DNA methyltransferases
13433 (Dnmt1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
BAH
DNA_methylase
DNMT1-RFD
DMAP_binding
zf-CXXC
HTH_12
Motif
Other DBs
NCBI-GeneID:
13433
NCBI-ProteinID:
NP_001186360
MGI:
94912
Ensembl:
ENSMUSG00000004099
UniProt:
P13864
Q3UHZ3
Structure
PDB
PDBj
LinkDB
All DBs
Position
9:complement(20818501..20871084)
Genome browser
AA seq
1620 aa
AA seq
DB search
MPARTAPARVPALASPAGSLPDHVRRRLKDLERDGLTEKECVREKLNLLHEFLQTEIKSQ
LCDLETKLHKEELSEEGYLAKVKSLLNKDLSLENGTHTLTQKANGCPANGSRPTWRAEMA
DSNRSPRSRPKPRGPRRSKSDSDTLSVETSPSSVATRRTTRQTTITAHFTKGPTKRKPKE
ESEEGNSAESAAEERDQDKKRRVVDTESGAAAAVEKLEEVTAGTQLGPEEPCEQEDDNRS
LRRHTRELSLRRKSKEDPDREARPETHLDEDEDGKKDKRSSRPRSQPRDPAAKRRPKEAE
PEQVAPETPEDRDEDEREEKRRKTTRKKLESHTVPVQSRSERKAAQSKSVIPKINSPKCP
ECGQHLDDPNLKYQQHPEDAVDEPQMLTSEKLSIYDSTSTWFDTYEDSPMHRFTSFSVYC
SRGHLCPVDTGLIEKNVELYFSGCAKAIHDENPSMEGGINGKNLGPINQWWLSGFDGGEK
VLIGFSTAFAEYILMEPSKEYEPIFGLMQEKIYISKIVVEFLQNNPDAVYEDLINKIETT
VPPSTINVNRFTEDSLLRHAQFVVSQVESYDEAKDDDETPIFLSPCMRALIHLAGVSLGQ
RRATRRVMGATKEKDKAPTKATTTKLVYQIFDTFFSEQIEKYDKEDKENAMKRRRCGVCE
VCQQPECGKCKACKDMVKFGGTGRSKQACLKRRCPNLAVKEADDDEEADDDVSEMPSPKK
LHQGKKKKQNKDRISWLGQPMKIEENRTYYQKVSIDEEMLEVGDCVSVIPDDSSKPLYLA
RVTALWEDKNGQMMFHAHWFCAGTDTVLGATSDPLELFLVGECENMQLSYIHSKVKVIYK
APSENWAMEGGTDPETTLPGAEDGKTYFFQLWYNQEYARFESPPKTQPTEDNKHKFCLSC
IRLAELRQKEMPKVLEQIEEVDGRVYCSSITKNGVVYRLGDSVYLPPEAFTFNIKVASPV
KRPKKDPVNETLYPEHYRKYSDYIKGSNLDAPEPYRIGRIKEIHCGKKKGKVNEADIKLR
LYKFYRPENTHRSYNGSYHTDINMLYWSDEEAVVNFSDVQGRCTVEYGEDLLESIQDYSQ
GGPDRFYFLEAYNSKTKNFEDPPNHARSPGNKGKGKGKGKGKGKHQVSEPKEPEAAIKLP
KLRTLDVFSGCGGLSEGFHQAGISETLWAIEMWDPAAQAFRLNNPGTTVFTEDCNVLLKL
VMAGEVTNSLGQRLPQKGDVEMLCGGPPCQGFSGMNRFNSRTYSKFKNSLVVSFLSYCDY
YRPRFFLLENVRNFVSYRRSMVLKLTLRCLVRMGYQCTFGVLQAGQYGVAQTRRRAIILA
AAPGEKLPLFPEPLHVFAPRACQLSVVVDDKKFVSNITRLSSGPFRTITVRDTMSDLPEI
QNGASNSEIPYNGEPLSWFQRQLRGSHYQPILRDHICKDMSPLVAARMRHIPLFPGSDWR
DLPNIQVRLGDGVIAHKLQYTFHDVKNGYSSTGALRGVCSCAEGKACDPESRQFSTLIPW
CLPHTGNRHNHWAGLYGRLEWDGFFSTTVTNPEPMGKQGRVLHPEQHRVVSVRECARSQG
FPDSYRFFGNILDRHRQVGNAVPPPLAKAIGLEIKLCLLSSARESASAAVKAKEEAATKD
NT seq
4863 nt
NT seq
+upstream
nt +downstream
nt
atgccagcgcgaacagctccagcccgagtgcctgcgcttgcctccccggcaggctcgctc
ccggaccatgtccgcaggcggctcaaagacttggaaagagatggcttaacagaaaaggag
tgtgtgagggagaaattaaacttactgcatgaattcctgcaaacagaaataaaaagccag
ttgtgtgacttggaaaccaaattacataaagaggaattatctgaggaaggctacctggct
aaagtcaagtccctcttaaataaggatttgtccttggagaacggaacacacactctcact
caaaaagccaacggttgtcccgccaacgggagccggccaacctggagagcagaaatggca
gactcaaatagatccccaagatccaggcccaagcctcggggacccaggagaagcaagtcg
gacagtgacaccctttcagttgaaacttcacctagttccgtggctacgaggagaaccacc
aggcagaccaccatcacggctcacttcacgaagggccccactaaacggaaacccaaggaa
gagtcggaagaggggaactcggctgagtcggctgcagaggagagagaccaggataagaaa
cgcagagttgtagacacagagagtggtgctgcagctgctgtggagaaactggaagaggta
acagcgggaacccagctgggtccggaagagccatgtgaacaggaagatgacaacaggagt
cttcgacgtcacaccagagagctatcattgaggcggaaatcaaaggaggatccagacaga
gaagcaagaccggaaactcacttggacgaggacgaggacggaaaaaaggataaaagaagt
tccagacccaggagccagcccagagatccagctgccaaacggagacccaaggaagcagag
ccagagcaggtagctccagagactcccgaggacagagacgaggatgagagggaggagaag
agacgaaaaacgacacgtaaaaaactggagtcacacaccgttcccgttcagagcagatcg
gagagaaaagccgctcaaagcaaaagtgtgatcccgaagatcaactcaccaaagtgcccc
gagtgtggccagcacctagacgaccctaacctgaagtaccagcagcaccctgaggatgct
gtggatgaaccccagatgttgaccagtgagaaactgtccatctacgactccacctcgacc
tggtttgatacttatgaagattctcccatgcataggttcacttccttcagtgtgtactgc
agtcgcgggcacctgtgtcctgtcgacaccggtctcattgagaagaatgtagagctctac
ttttctgggtgtgccaaagcaattcatgacgagaatccatctatggaaggtggtattaat
ggcaaaaacctcgggccaatcaatcagtggtggctcagtggctttgatggtggcgagaag
gtgctcattggcttctccactgcatttgctgaatacattttgatggagcccagcaaagag
tatgagccaatatttgggctgatgcaggagaaaatttacatcagcaagattgttgttgag
ttcctgcaaaacaatcctgatgctgtatatgaagacctgatcaataagattgagaccact
gttcctccttctaccattaatgtgaaccggttcacagaggactccctcttacgccacgcc
cagtttgtagtgagccaggtagagagttacgacgaagccaaggacgatgatgagaccccc
atcttcttgtctccctgtatgagagccctgatccatttggctggtgtctccctgggacag
aggcgagcaacaaggcgcgtcatgggtgctaccaaggagaaggacaaagcacccacgaaa
gccaccaccaccaagctggtctatcagatctttgacactttcttctcagagcagattgag
aagtatgataaggaggacaaggagaatgccatgaagcgccgccgctgtggtgtctgtgag
gtctgtcagcagcctgagtgtgggaagtgcaaggcgtgcaaagatatggtgaagtttggt
ggcactggacggagtaagcaggcttgcctcaagaggaggtgtcctaacttggcggtgaag
gaggcagacgacgatgaagaggctgatgatgatgtgtcagagatgccatcacccaaaaag
ctgcatcaggggaagaagaagaagcagaacaaggaccgcatctcctggcttgggcagcct
atgaagattgaagagaatagaacttactatcagaaggtgagcatcgatgaggagatgcta
gaggtgggcgactgcgtctcggtcattccagatgattcctccaaaccactctatctagcc
agggtcacagctctgtgggaagacaaaaatggtcagatgatgttccatgcgcactggttc
tgcgctgggacagacacagtcctgggagccacctccgaccccctggaactgttcctggtg
ggcgagtgcgaaaacatgcagctttcctacatccacagcaaggtcaaggtcatctacaaa
gccccttctgaaaactgggccatggagggaggcacagaccctgagaccacactgcctggg
gctgaggatggcaagacttacttcttccagctctggtacaaccaggagtacgcaaggttt
gaatccccacccaagacccagccgaccgaggacaacaagcacaagttctgcctatcttgt
atccggctggctgagctgagacaaaaagaaatgcccaaggtcctggaacaaattgaggag
gtggatggccgggtctactgcagttccatcaccaagaatggtgttgtctaccgactgggt
gacagtgtgtaccttcctcccgaggcctttactttcaacatcaaagtggctagccccgtg
aaacgcccaaagaaggatcctgtgaacgagaccctgtaccctgagcactaccgcaagtat
tctgactacatcaaggggagcaacctggatgctccagagccctatcgcatcggtcggata
aaagagatccactgtggcaagaagaaaggcaaggtcaacgaggcagacatcaagctgagg
ctctacaagttctacaggcctgagaatacccacaggtcctacaacggatcctatcacact
gacatcaacatgctttactggagcgacgaggaagctgtggtgaacttcagcgacgtgcag
ggccgctgtaccgtggagtacggggaagacctacttgagagcatccaggattattcacaa
gggggccctgaccgcttctacttcctcgaggcctacaattcaaagaccaagaactttgaa
gacccaccaaaccatgcccgcagccctgggaacaaagggaaagggaaggggaaagggaag
gggaaggggaagcatcaggtgtcagagcccaaagagcctgaggcagccatcaaactgccc
aagctccggaccctggatgtgttttccggctgtggagggttatcggaaggattccaccaa
gcaggcatctcggaaacgctgtgggccatcgagatgtgggacccggcagcccaggcattt
cggctgaacaaccccggcaccacagtgttcacagaggactgcaacgtgcttcttaagctg
gtcatggctggggaggtgaccaactctctgggccaaaggctgccacagaagggcgatgtg
gagatgctgtgtggtgggccaccctgccagggcttcagtggcatgaaccgcttcaactcc
cgcacttactccaagttcaaaaactccctagtggtctccttcctcagctactgtgactac
taccggcctcggttcttccttctggagaacgtcaggaacttcgtgtcctacagacgctcc
atggtgctgaagctcacactgcgctgcctggtccgcatgggctaccagtgcacctttggt
gtgctccaggctggacagtatggcgtggcccagacacgaaggagggccatcatcttggct
gcagccccaggagaaaagctgcctctgttcccagagcctctgcatgtgtttgcgccccgt
gcctgccagctgagcgttgtggtggatgacaagaagtttgttagcaacataacgaggctg
agctcggggcccttccgaaccatcaccgtgcgagacaccatgtctgacctccccgagatc
cagaatggagcctcgaattctgagatcccctacaatggagagccactgtcctggttccag
aggcagctgcgaggatcacactaccagcccatcctcagggaccatatctgcaaggacatg
agcccactggtggctgcccgcatgcggcacatcccactgttcccaggatcagattggcgt
gacctgcccaacatacaggtgcggctgggagatggcgtcatagcccataagctacagtac
acctttcatgatgtgaaaaatggctacagcagcaccggtgccctgcgtggagtctgttcc
tgtgcagaaggcaaggcctgcgaccctgagtccaggcaattcagcaccctcatcccctgg
tgcctgccgcacactgggaaccggcacaaccactgggctggcctctacgggcgtctggag
tgggatggcttcttcagcaccactgtcaccaaccctgagcccatgggcaagcagggtcgg
gtgctccacccggagcagcaccgggtcgtgagtgttcgggaatgtgcccgctcccagggc
tttccagatagctaccggttcttcggcaacatcctggacagacaccggcaggtgggtaat
gctgtgccaccacccctggccaaagccattggcctggagattaagctctgcctgctgtcc
agtgctcgggagagcgcatcagctgcagttaaagcaaaagaggaggctgctaccaaggac
tag
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