Mus musculus (house mouse): 13819
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Entry
13819 CDS
T01002
Symbol
Epas1, HIF-2alpha, HIF2A, HLF, HRF, MOP2, bHLHe73
Name
(RefSeq) endothelial PAS domain protein 1
KO
K09095
hypoxia-inducible factor 2 alpha
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04066
HIF-1 signaling pathway
mmu05200
Pathways in cancer
mmu05211
Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
13819 (Epas1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
13819 (Epas1)
09162 Cancer: specific types
05211 Renal cell carcinoma
13819 (Epas1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
mmu03000
]
13819 (Epas1)
04131 Membrane trafficking [BR:
mmu04131
]
13819 (Epas1)
Transcription factors [BR:
mmu03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
13819 (Epas1)
Membrane trafficking [BR:
mmu04131
]
Autophagy
Pexophagy
Other pexophagy associated proteins
13819 (Epas1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
HIF-1
PAS
PAS_9
PAS_4
HLH
Corona_I
Motif
Other DBs
NCBI-GeneID:
13819
NCBI-ProteinID:
NP_034267
MGI:
109169
Ensembl:
ENSMUSG00000024140
UniProt:
P97481
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:87061292..87140838
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AA seq
874 aa
AA seq
DB search
MTADKEKKRSSSELRKEKSRDAARCRRSKETEVFYELAHELPLPHSVSSHLDKASIMRLA
ISFLRTHKLLSSVCSENESEAEADQQMDNLYLKALEGFIAVVTQDGDMIFLSENISKFMG
LTQVELTGHSIFDFTHPCDHEEIRENLTLKNGSGFGKKSKDVSTERDFFMRMKCTVTNRG
RTVNLKSATWKVLHCTGQVRVYNNCPPHSSLCGSKEPLLSCLIIMCEPIQHPSHMDIPLD
SKTFLSRHSMDMKFTYCDDRILELIGYHPEELLGRSAYEFYHALDSENMTKSHQNLCTKG
QVVSGQYRMLAKHGGYVWLETQGTVIYNPRNLQPQCIMCVNYVLSEIEKNDVVFSMDQTE
SLFKPHLMAMNSIFDSSDDVAVTEKSNYLFTKLKEEPEELAQLAPTPGDAIISLDFGSQN
FDEPSAYGKAILPPGQPWVSGLRSHSAQSESGSLPAFTVPQADTPGNTTPSASSSSSCST
PSSPEDYYSSLENPLKIEVIEKLFAMDTEPRDPGSTQTDFSELDLETLAPYIPMDGEDFQ
LSPICPEEPLMPESPQPTPQHCFSTMTSIFQPLTPGATHGPFFLDKYPQQLESRKTESEH
WPMSSIFFDAGSKGSLSPCCGQASTPLSSMGGRSNTQWPPDPPLHFGPTKWPVGDQSAES
LGALPVGSSQLEPPSAPPHVSMFKMRSAKDFGARGPYMMSPAMIALSNKLKLKRQLEYEE
QAFQDTSGGDPPGTSSSHLMWKRMKSLMGGTCPLMPDKTISANMAPDEFTQKSMRGLGQP
LRHLPPPQPPSTRSSGENAKTGFPPQCYASQFQDYGPPGAQKVSGVASRLLGPSFEPYLL
PELTRYDCEVNVPVPGSSTLLQGRDLLRALDQAT
NT seq
2625 nt
NT seq
+upstream
nt +downstream
nt
atgacagctgacaaggagaaaaaaaggagcagctcagagctgaggaaggagaaatcccgt
gatgccgcgaggtgccggcgcagcaaggagacggaggtcttctatgagttggctcatgag
ttgcccctgcctcacagtgtgagctcccacctggacaaagcctccatcatgcgcctggcc
atcagcttccttcggacacataagctcctgtcctcagtctgctctgaaaatgaatctgaa
gctgaggccgaccagcaaatggataacttgtacctgaaagccttggagggtttcattgct
gtggtgacccaagacggtgacatgatctttctgtcggaaaacatcagcaagttcatggga
cttactcaggtagaactaacaggacacagcatctttgacttcactcatccttgcgaccat
gaggagatccgtgagaacctgactctcaaaaacggctctggttttgggaagaagagcaaa
gacgtgtccaccgagcgtgacttcttcatgaggatgaagtgcacggtcaccaacagaggc
cggactgtcaacctcaagtcggccacctggaaggtcctgcactgcaccgggcaagtgaga
gtctacaacaactgcccccctcacagtagcctctgtggctccaaggagcccctgctgtcc
tgccttatcatcatgtgtgagccaatccagcacccatcccacatggacatccccctggac
agcaagactttcctgagccgccacagcatggacatgaagttcacctactgtgacgacaga
atcttggaactgattggttaccaccccgaggagctacttggacgctctgcctatgagttc
taccatgccctggattcggagaacatgaccaaaagtcaccagaacttgtgcaccaagggg
caggtggtatctggccagtaccggatgctagccaaacacggaggatatgtgtggctggag
acccaggggacggtcatctacaacccccgcaacctgcagcctcagtgtatcatgtgtgtc
aactatgtgctgagtgagatcgagaagaacgacgtggtgttctccatggaccagaccgaa
tccctgttcaagccacacctgatggccatgaacagcatctttgacagcagtgacgatgtg
gctgtaactgagaagagcaactacctgttcaccaaactgaaggaggagcccgaggaactg
gcccagttggcccccaccccaggagatgccattatttctctcgatttcggaagccagaac
ttcgatgaaccctcagcctatggcaaggccatccttcccccgggccagccatgggtctcg
gggctgaggagccacagtgcccagagcgagtccgggagcctgccagccttcactgtgccc
caggcagacaccccagggaacactacacccagtgcttcaagcagcagtagctgctccacg
cccagcagccctgaggactactattcatccttggagaatcccttgaagatcgaagtgatt
gagaagcttttcgccatggacacggagccgagggacccgggcagtacccagacggacttc
agtgaactggatttggagaccttggcaccctacatccctatggacggcgaggacttccag
ctgagccccatctgcccagaggagccgctcatgccagagagcccccagcccaccccccag
cactgcttcagtaccatgaccagcatcttccagccgctcaccccgggggccacccacggc
cccttcttcctcgataagtacccgcagcagttggaaagcaggaagacagagtctgagcac
tggcccatgtcttccatcttctttgatgctgggagcaaagggtccctgtctccatgctgt
ggccaggccagcacccctctctcttctatgggaggcagatccaacacgcagtggcccccg
gatccaccattacatttcggccctactaagtggcctgtgggtgatcagagtgctgaatcc
ctgggagccctgccggtggggtcatcgcagttggaacctccgagcgccccgcctcatgtc
tccatgttcaagatgaggtctgcaaaggacttcggggcccgaggtccatacatgatgagc
ccagccatgatcgccctgtccaacaagctgaagctaaagcggcagctggagtatgaggag
caagccttccaagacacaagcgggggggaccctccaggcaccagcagttcacacttgatg
tggaaacgtatgaagagcctcatgggcgggacctgtcctttgatgcctgacaagaccatc
agtgcgaacatggcccccgatgaattcacccaaaaatctatgagaggcctgggccagcca
ctgagacacctgccacctccccagccaccatctaccaggagctcaggggagaacgccaag
actgggttcccgccacagtgctatgcctcccagttccaggactacggtcctccaggagct
caaaaggtgtcaggcgtggccagtcgactgctggggccatcgttcgagccttacctgttg
ccggaactgaccagatatgactgtgaggtgaacgtgcccgtgcctggaagctccacactc
ctgcaggggagagaccttctcagagctctggaccaggccacctga
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