Mus musculus (house mouse): 14013
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Entry
14013 CDS
T01002
Symbol
Mecom, D630039M04Rik, Evi-1, Evi1, Jbo, Mds, Mds1, Mds1-Evi1, Prdm3, Znfpr1b1
Name
(RefSeq) histone-lysine N-methyltransferase MECOM isoform 5
KO
K04462
[histone H3]-lysine9 N-methyltransferase (ecotropic virus integration site 1 protein) [EC:
2.1.1.367
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00310
Lysine degradation
mmu01100
Metabolic pathways
mmu04010
MAPK signaling pathway
mmu05200
Pathways in cancer
mmu05220
Chronic myeloid leukemia
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00310 Lysine degradation
14013 (Mecom)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
14013 (Mecom)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
14013 (Mecom)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
14013 (Mecom)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
mmu03000
]
14013 (Mecom)
03036 Chromosome and associated proteins [BR:
mmu03036
]
14013 (Mecom)
Enzymes [BR:
mmu01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.367 [histone H3]-lysine9 N-methyltransferase
14013 (Mecom)
Transcription factors [BR:
mmu03000
]
Eukaryotic type
Zinc finger
Cys2His2 PRDM
14013 (Mecom)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Histone modification proteins
HMTs (histone methyltransferases)
HKMTs (histone lysine methyltransferases)
14013 (Mecom)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
zf-C2H2
zf-H2C2_2
zf-C2H2_4
PRDM2_PR
zf-C2H2_6
zf-C2H2_jaz
SET
C2CH-3rd_BIRD-IDD
zf-met
zf-H2C2_5
Zap1_zf1
zf-BED
zf-C2H2_8
Zn_ribbon_8
DUF7128
zf-C2H2_11
CEP104_ZnF
Motif
Other DBs
NCBI-GeneID:
14013
NCBI-ProteinID:
NP_001357698
MGI:
95457
Ensembl:
ENSMUSG00000027684
UniProt:
P14404
Structure
PDB
PDBj
LinkDB
All DBs
Position
3:complement(30005445..30563937)
Genome browser
AA seq
1232 aa
AA seq
DB search
MRSKGRARKLATSNECAYGNYPEIPLEEMPDADADGITSVPSLHIQEPCSPATSSESFTP
KEGSPYKAPIYIPDDIPIPDEFELRESTMPGAGLGIWTKRKIEIGEKFGPYMGEQRSDLK
DSSYGWEILDEFCNVKFCIDASQPDVGSWLKYIRFAGCYDQHNLVACQINDQIFYRVVAD
IAPGEELLLFMKSEEDPHEPMAPDIHEERQHRCEDCDQLFESKAELADHQKFPCSTPHSA
FSMVEEDLQQNLESESDLREIHGNQDCKECDRVFPDLQSLEKHMLSHTEEREYKCDQCPK
AFNWKSNLIRHQMSHDSGKHYECENCAKVFTDPSNLQRHIRSQHVGARAHACPECGKTFA
TSSGLKQHKHIHSSVKPFICEVCHKSYTQFSNLCRHKRMHADCRTQIKCKDCGQMFSTTS
SLNKHRRFCEGKNHFAAGGFFGQGISLPGTPAMDKTSMVNMSHANPGLADYFGTNRHPAG
LTFPTAPGFSFSFPGLFPSGLYHRPPLIPASPPVKGLSSTEQSNKCQSPLLTHPQILPAT
QDILKALSKHPPVGDNKPVELLPERSSEERPLEKISDQSESSDLDDVSTPSGSDLETTSG
SDLESDLESDKEKCKENGKMFKDKVSPLQNLASITNKKEHNNHSVFSASVEEQSAVSGAV
NDSIKAIASIAEKYFGSTGLVGLQDKKVGALPYPSMFPLPFFPAFSQSMYPFPDRDLRSL
PLKMEPQSPSEVKKLQKGSSESPFDLTTKRKDEKPLTSGPSKPSGTPATSQDQPLDLSMG
SRGRASGTKLTEPRKNHVFGEKKGSNMDTRPSSDGSLQHARPTPFFMDPIYRVEKRKLTD
PLEALKEKYLRPSPGFLFHPQMSAIENMAEKLESFSALKPEASELLQSVPSMFSFRAPPN
TLPENLLRKGKERYTCRYCGKIFPRSANLTRHLRTHTGEQPYRCKYCDRSFSISSNLQRH
VRNIHNKEKPFKCHLCDRCFGQQTNLDRHLKKHENGNMSGTATSSPHSELESAGAILDDK
EDAYFTEIRNFIGNSNHGSQSPRNMEERMNGSHFKDKKALATSQNSDLLDDEEVEDEVLL
DEEDEDNDIPGKPRKELGVTRLDEEIPEDDYEEAGALEMSCKASPVRYKEEDYKSGLSAL
DHIRHFTDSLKMREMEENQYTDAELSSISSSHVPEELKQTLHRKSKSQAYAMMLSLSDKD
SLHPTSHSSSNVWHSMARAAAESSAIQSISHV
NT seq
3699 nt
NT seq
+upstream
nt +downstream
nt
atgagatccaaaggcagggcaaggaaactggccacaagtaatgagtgtgcctatggcaac
tatcctgaaatacctttggaagaaatgccagatgctgatgcagatgggataaccagtgtt
ccctccctccacattcaagagccatgctctcctgcgacgtccagtgagtcatttactcct
aaggagggctcgccatacaaagctcccatctacatccctgatgacatccctattcctgat
gagtttgagcttcgagagtcaactatgcctggagcaggacttggaatatggaccaaaagg
aagattgaaataggcgaaaagtttgggccatacatgggagagcagagatcagacctgaaa
gattccagctatggatgggagatcttagatgagttttgcaatgtgaagttctgcatagat
gccagtcaaccagatgtaggaagctggctcaagtacatcagattcgctggctgctatgat
cagcacaaccttgttgcatgccagataaatgatcagatattctaccgagtagtcgcagac
attgcgcctggggaagagctcttgctgttcatgaagagtgaagaggacccgcacgaaccc
atggcgcctgacatccacgaagaacggcagcaccgctgtgaggactgtgaccagctcttt
gaatccaaggcagagctagccgatcaccagaagttcccatgcagcacacctcactcggcc
ttctccatggtggaggaggacttgcaacaaaacctggagagtgagagcgatctccgagag
atccatggcaaccaggactgtaaggaatgtgaccgagttttccccgatctgcaaagcttg
gagaagcacatgctgtcacatactgaggagagggaatacaagtgtgatcagtgtcccaag
gcatttaactggaagtccaatttaattcgccaccagatgtcacatgacagtggaaagcac
tatgagtgtgaaaactgtgccaaggttttcacggaccctagcaaccttcagcgacacatt
cgatctcagcatgttggtgcccgggctcatgcttgccccgagtgtggtaaaacatttgcc
acttcgtcaggcctcaaacagcacaagcacatccacagcagtgtgaagccctttatctgt
gaggtctgccataaatcctatactcagttttcaaacctttgtcgtcataagcgcatgcat
gctgattgcagaacccaaatcaagtgcaaagactgtggacaaatgttcagcactacgtct
tccttaaataaacacaggaggttttgtgagggcaagaaccattttgcggcaggtggattt
tttggccaaggcatttcacttcctggaaccccagctatggataaaacgtccatggttaat
atgagtcatgccaacccgggcctggctgactattttggcaccaataggcatcctgctggt
cttacctttccaacagctcctggattttcctttagctttcctggtctgtttccttcgggc
ttataccacaggcctcctttgatacccgctagtcctcctgttaaaggattatcaagtacc
gaacagtcaaacaaatgtcaaagtcccctcttgacacatcctcagatactgccagctaca
caggatattttgaaggcactatctaaacacccacctgtaggggacaataagccagtggaa
ctgctgcccgagaggtcctctgaagagaggccccttgagaaaatcagtgaccagtcagag
agtagtgaccttgatgatgtcagtacaccaagtggcagtgacctggaaacaacctcgggc
tctgatctggaaagtgaccttgaaagtgataaagagaaatgtaaagaaaatggtaaaatg
ttcaaagacaaagtaagccctctgcagaatctggcttcgataactaataagaaagaacac
aacaatcattccgttttctcagcatctgtagaggagcaaagtgccgtgtcaggagctgtg
aatgattctataaaggctattgcgtctattgctgaaaaatactttggttctacaggactg
gtggggctgcaagacaaaaaagttggagcgttaccttacccttccatgtttcccctcccg
ttttttccagcattctctcaatcaatgtacccatttcctgatagagacttgaggtcgtta
cctttgaaaatggagccccaatcaccaagtgaagttaagaaactgcagaagggaagctct
gagtccccttttgacctcaccactaagagaaaggatgagaagcccttgacttcaggcccc
tcgaagccttcaggaacaccagccacaagccaagaccagcccctggatctaagtatgggc
agtaggggtagagccagtgggacaaagttgactgagcctcgaaaaaaccatgtgtttggg
gaaaagaaaggaagcaacatggatactaggccatcttcagatggctccttgcagcatgcc
agacccactcccttcttcatggaccccatttatagagtagagaaaagaaagttaactgac
ccgcttgaagctttgaaagaaaaatacttgagaccttctccaggattcttgtttcacccg
caaatgtcagcaattgagaacatggcagaaaagctggaaagcttcagcgccctcaaacct
gaggccagcgagctcctgcagtccgtgccctccatgttcagcttccgagctcctcccaac
accctgccagagaacctgctgcggaaggggaaagagcgctacacctgcaggtactgtggc
aagatatttccaaggtctgcgaacctaacacggcacttgagaacccacacaggagagcaa
ccttacagatgcaaatactgtgatagatcattcagcatttcttccaacctgcagcgacat
gtgcgcaacatccacaacaaggagaagccatttaagtgtcatttatgtgacagatgtttt
ggtcaacaaaccaatcttgacagacacctgaagaaacatgagaacggcaacatgtctggg
acggcaacgtcctcgcctcactcagagctagaaagcgcaggcgcaatcctggatgacaaa
gaagatgcgtactttacagagatccgcaatttcatcgggaacagcaaccatggtagccag
tctcctcggaacatggaagagaggatgaatggcagtcacttcaaggataaaaaggctttg
gcaaccagccaaaattcagatttattggatgatgaagaagtagaagatgaggtgttgttg
gatgaggaggatgaagacaatgatattcctggaaagcccagaaaggagctaggggtgact
cgtttagacgaggagatcccggaggatgactacgaagaagctggtgccctggagatgagc
tgtaaggcgtccccggtgaggtataaagaggaagactataaatctggcctttctgctcta
gatcacataaggcacttcacagatagcctcaaaatgagggaaatggaagagaatcaatac
actgacgctgagctgtcctccattagttcttctcatgtgccagaggagcttaaacagacg
ttacacagaaagtccaaatcacaggcatatgctatgatgttgtcactgtctgacaaggat
tccctccatcccacctcccacagttcctccaacgtgtggcacagcatggcaagggctgca
gcagaatccagtgccatccagtccataagccatgtatga
DBGET
integrated database retrieval system
