Mus musculus (house mouse): 14360
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Entry
14360 CDS
T01002
Symbol
Fyn
Name
(RefSeq) Fyn proto-oncogene
KO
K05703
tyrosine-protein kinase Fyn [EC:
2.7.10.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04071
Sphingolipid signaling pathway
mmu04072
Phospholipase D signaling pathway
mmu04360
Axon guidance
mmu04380
Osteoclast differentiation
mmu04510
Focal adhesion
mmu04520
Adherens junction
mmu04611
Platelet activation
mmu04650
Natural killer cell mediated cytotoxicity
mmu04660
T cell receptor signaling pathway
mmu04664
Fc epsilon RI signaling pathway
mmu04725
Cholinergic synapse
mmu05020
Prion disease
mmu05416
Viral myocarditis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04072 Phospholipase D signaling pathway
14360 (Fyn)
04071 Sphingolipid signaling pathway
14360 (Fyn)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
14360 (Fyn)
04520 Adherens junction
14360 (Fyn)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
14360 (Fyn)
04650 Natural killer cell mediated cytotoxicity
14360 (Fyn)
04660 T cell receptor signaling pathway
14360 (Fyn)
04664 Fc epsilon RI signaling pathway
14360 (Fyn)
09156 Nervous system
04725 Cholinergic synapse
14360 (Fyn)
09158 Development and regeneration
04360 Axon guidance
14360 (Fyn)
04380 Osteoclast differentiation
14360 (Fyn)
09160 Human Diseases
09164 Neurodegenerative disease
05020 Prion disease
14360 (Fyn)
09166 Cardiovascular disease
05416 Viral myocarditis
14360 (Fyn)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
14360 (Fyn)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
14360 (Fyn)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
14360 (Fyn)
Protein kinases [BR:
mmu01001
]
Non-receptor tyrosine kinases
SRC family
14360 (Fyn)
Membrane trafficking [BR:
mmu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
14360 (Fyn)
Endocytosis
Lipid raft mediated endocytosis
Flotillin-dependent endocytosis
14360 (Fyn)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH3_10
SH3_3
ABC1
Haspin_kinase
SH2_1
zf-RING_14
DUF7063
Motif
Other DBs
NCBI-GeneID:
14360
NCBI-ProteinID:
NP_001116365
MGI:
95602
Ensembl:
ENSMUSG00000019843
UniProt:
P39688
Structure
PDB
PDBj
LinkDB
All DBs
Position
10:39245735..39441377
Genome browser
AA seq
537 aa
AA seq
DB search
MGCVQCKDKEAAKLTEERDGSLNQSSGYRYGTDPTPQHYPSFGVTSIPNYNNFHAAGGQG
LTVFGGVNSSSHTGTLRTRGGTGVTLFVALYDYEARTEDDLSFHKGEKFQILNSSEGDWW
EARSLTTGETGYIPSNYVAPVDSIQAEEWYFGKLGRKDAERQLLSFGNPRGTFLIRESET
TKGAYSLSIRDWDDMKGDHVKHYKIRKLDNGGYYITTRAQFETLQQLVQHYSERAAGLCC
RLVVPCHKGMPRLTDLSVKTKDVWEIPRESLQLIKRLGNGQFGEVWMGTWNGNTKVAIKT
LKPGTMSPESFLEEAQIMKKLKHDKLVQLYAVVSEEPIYIVTEYMSKGSLLDFLKDGEGR
ALKLPNLVDMAAQVAAGMAYIERMNYIHRDLRSANILVGNGLICKIADFGLARLIEDNEY
TARQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELVTKGRVPYPGMNNREVLEQVE
RGYRMPCPQDCPISLHELMIHCWKKDPEERPTFEYLQGFLEDYFTATEPQYQPGENL
NT seq
1614 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtgtgcaatgtaaggataaagaagcagcgaaactgacagaggagagggacggc
agcctgaaccagagctctgggtaccgctatggcacagaccccacccctcagcactacccc
agcttcggcgtgacctccatcccgaactacaacaacttccacgcagctgggggccaggga
ctcaccgtctttgggggtgtgaactcctcctctcacactgggaccctacgcacgagagga
gggacaggagtgacactgtttgtggcgctttatgactatgaagcacggacggaagatgac
ctgagttttcacaaaggagaaaaatttcaaatattgaacagctcggaaggagactggtgg
gaagcccgctccttgacaaccggggaaactggttacattcccagcaattacgtggctcca
gttgactccatccaggcagaagagtggtactttggaaaacttggccgcaaagatgctgag
agacagctcctgtcctttggaaacccaagaggtacctttcttatccgcgagagcgaaacc
accaaaggtgcctactcactttccatccgtgattgggatgatatgaaaggggaccacgtc
aaacattataaaatccgcaagcttgacaatggtggatactatatcacaacgcgggcccag
tttgaaacacttcagcaactggtacagcattactcagagagagccgcaggtctctgctgc
cgcctagtagttccctgtcacaaagggatgccaaggcttaccgatctgtctgtcaaaacc
aaagatgtctgggaaatccctcgagaatccctgcagttgatcaagagactgggaaatggg
cagtttggggaagtatggatgggtacctggaatggaaatacaaaagtagccataaagacc
cttaagccaggcaccatgtctccggagtccttcctggaggaggcgcagatcatgaagaag
ctgaagcatgacaagctggtgcagctctacgcggtcgtgtctgaggagcccatttacatc
gtcacggagtacatgagcaaaggaagtttgcttgacttcttaaaagatggtgaaggaaga
gctctgaagttgccaaaccttgtggacatggcggcacaggttgctgcaggaatggcttac
atcgagcgcatgaattatatccacagagatctgcgatcagcaaacattctagtggggaat
ggactaatttgcaagattgctgactttggattggctcggttgattgaagacaatgaatac
acagcaagacaaggtgcgaagtttcccattaagtggacagcccccgaagcggccctgtat
ggaaggttcacaatcaagtctgacgtatggtcttttggaatcttactcacagagctggtc
accaaaggaagagtgccatacccaggcatgaacaaccgggaggtgctggagcaggtggag
agaggctataggatgccctgcccacaggactgcccgatctccctgcacgagctcatgatc
cactgctggaaaaaggatccggaagagcgcccgaccttcgagtacttgcagggcttcctg
gaggactactttacggccacagagccccagtatcagcccggtgaaaacctgtga
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