KEGG   Mus musculus (house mouse): 14466
Entry
14466             CDS       T01002                                 
Symbol
Gba1, GC, GCase, GLUC, Gba, betaGC
Name
(RefSeq) glucosylceramidase beta 1
  KO
K01201  glucosylceramidase [EC:3.2.1.45]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00511  Other glycan degradation
mmu00600  Sphingolipid metabolism
mmu01100  Metabolic pathways
mmu04142  Lysosome
mmu04382  Cornified envelope formation
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09103 Lipid metabolism
   00600 Sphingolipid metabolism
    14466 (Gba1)
  09107 Glycan biosynthesis and metabolism
   00511 Other glycan degradation
    14466 (Gba1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04142 Lysosome
    14466 (Gba1)
 09150 Organismal Systems
  09158 Development and regeneration
   04382 Cornified envelope formation
    14466 (Gba1)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.2  Glycosylases
   3.2.1  Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
    3.2.1.45  glucosylceramidase
     14466 (Gba1)
SSDB
Motif
Pfam: Glyco_hydro_30 Glyco_hydro_30C
Other DBs
NCBI-GeneID: 14466
NCBI-ProteinID: NP_001070879
MGI: 95665
Ensembl: ENSMUSG00000028048
UniProt: P17439
LinkDB
Position
3:89110235..89119944
AA seq 515 aa
MAARLIGFFLFQAVSWAYGAQPCIPKSFGYSSVVCVCNASYCDSLDPVTLPALGTFSRYE
STRRGRRMELSVGAIQANRTGTGLLLTLQPEKKFQKVKGFGGAMTDATALNILALSPPTQ
KLLLRSYFSTNGIEYNIIRVPMASCDFSIRVYTYADTPNDFQLSNFSLPEEDTKLKIPLI
HQALKMSSRPISLFASPWTSPTWLKTNGRVNGKGSLKGQPGDIFHQTWANYFVKFLDAYA
KYGLRFWAVTAENEPTAGLFTGYPFQCLGFTPEHQRDFISRDLGPALANSSHDVKLLMLD
DQRLLLPRWAEVVLSDPEAAKYVHGIAVHWYMDFLAPAKATLGETHRLFPNTMLFASEAC
VGSKFWEQSVRLGSWDRGMQYSHSIITNLLYHVTGWTDWNLALNPEGGPNWVRNFVDSPI
IVDIPKDAFYKQPMFYHLGHFSKFIPEGSQRVALVASESTDLETVALLRPDGSAVVVVLN
RSSEDVPLTISDPDLGFLETVSPGYSIHTYLWRRQ
NT seq 1548 nt   +upstreamnt  +downstreamnt
atggctgccaggctcatcggattcttcctatttcaggcggtatcttgggcatatggtgcc
caaccctgcatccccaaaagctttggctacagctcagtggtctgtgtctgtaatgcatcg
tactgtgactctcttgaccccgtgaccttaccggctctgggtaccttcagccgttacgag
agcactcgacgtggacgtcggatggagctgagtgtcggggccatccaggccaatcgcact
ggcacagggttactactcactttgcagccagaaaagaagttccagaaagtgaaaggattt
ggaggcgccatgacagacgccactgcgctcaacatccttgctttgtccccacctactcag
aagctgctactcagatcctacttctctaccaacggaattgaatataacatcatccgggta
cccatggccagttgtgacttctccatccgtgtctatacctatgctgacacccctaacgac
ttccagttatccaacttcagcctcccagaagaagacaccaagctcaagatacccctgatt
caccaagccctgaagatgtcctcacgccccatttcactctttgccagtccctggacatca
cccacttggctcaagaccaatggaagagtgaatgggaaggggtcgctcaagggtcagcca
ggggatatctttcaccagacctgggccaattactttgtcaagtttctggatgcttatgct
aagtatggcctaagattctgggcagtgacagcggagaatgaacctacagcagggctcttc
acggggtaccccttccagtgcctgggcttcactcctgaacaccagagagacttcatttcc
cgtgacctagggccagcccttgccaacagttcccatgatgtgaagctactcatgctagat
gaccaacgcttgctgctaccccgctgggcagaggtggtgctctctgatccagaggcagct
aagtacgttcatggcattgctgttcactggtatatggatttcctggctccagccaaagct
actttaggagagacacaccgcttgttccccaacacaatgctctttgcttcggaggcctgc
gtgggctccaagttctgggaacagagtgttcggttgggctcctgggatcgagggatgcag
tacagtcacagcatcattacgaacctcctttaccacgtaactggatggacggactggaac
cttgccctgaatcctgaaggagggcccaactgggtccgcaactttgtcgatagccccatt
attgtcgacatccccaaagacgcattttacaaacagcccatgttctaccatcttggccac
ttcagcaagttcattcccgagggatcccagagagtggcgttggtggccagtgagagcact
gacttggaaacagtagcactgttacgccctgacggctctgcagttgtggtcgtgttaaac
cgatcttcggaggatgtccctcttaccatcagtgatcctgacctgggcttcctggagacc
gtgtcacctggctactccattcacacttacctgtggcgtcgccagtga

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