KEGG   Mus musculus (house mouse): 14782
Entry
14782             CDS       T01002                                 
Symbol
Gsr, D8Ertd238e, Gr-1, Gr1
Name
(RefSeq) glutathione reductase
  KO
K00383  glutathione reductase (NADPH) [EC:1.8.1.7]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00480  Glutathione metabolism
mmu01100  Metabolic pathways
mmu04918  Thyroid hormone synthesis
mmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    14782 (Gsr)
 09150 Organismal Systems
  09152 Endocrine system
   04918 Thyroid hormone synthesis
    14782 (Gsr)
 09160 Human Diseases
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    14782 (Gsr)
Enzymes [BR:mmu01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.7  glutathione-disulfide reductase
     14782 (Gsr)
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox Pyr_redox_3 FAD_oxidored FAD_binding_2 AlaDh_PNT_C GIDA HI0933_like NAD_binding_8 DAO Lys_Orn_oxgnase
Other DBs
NCBI-GeneID: 14782
NCBI-ProteinID: NP_034474
MGI: 95804
Ensembl: ENSMUSG00000031584
UniProt: P47791
LinkDB
Position
8:34143266..34188190
AA seq 500 aa
MALLPRALGVGAAPSLRRAARALTCAMASPGEPQPPAPDTSSFDYLVIGGGSGGLASARR
AAELGARAAVVESHKLGGTCVNVGCVPKKVMWNTAVHSEFMHDHVDYGFQSCEGKFSWHV
IKQKRDAYVSRLNTIYQNNLTKSHIEIIHGYATFADGPRPTVEVNGKKFTAPHILIATGG
VPTVPHESQIPGASLGITSDGFFQLEDLPSRSVIVGAGYIAVEIAGILSALGSKTSLMIR
HDKVLRNFDSLISSNCTEELENAGVEVLKFTQVKEVKKTSSGLELQVVTSVPGRKPTTTM
IPDVDCLLWAIGRDPNSKGLNLNKVGIQTDEKGHILVDEFQNTNVKGVYAVGDVCGKALL
TPVAIAAGRKLAHRLFECKQDSKLDYDNIPTVVFSHPPIGTVGLTEDEAVHKYGKDNVKI
YSTAFTPMYHAVTTRKTKCVMKMVCANKEEKVVGIHMQGIGCDEMLQGFAVAVKMGATKA
DFDNTVAIHPTSSEELVTLR
NT seq 1503 nt   +upstreamnt  +downstreamnt
atggcgctgctgccccgggcgctgggcgtgggcgcggccccgagcctgcggcgggcagcg
cgcgcgctcacctgcgccatggcgagtcccggcgagccgcagcccccggccccggacacc
tcttccttcgactacctggtgatcggcggcggctccggcgggctggccagcgcgcggcgg
gcggcggagctcggcgccagggccgcggtggtggagagtcacaagctgggtggcacttgc
gtgaatgttggatgtgtacccaaaaaggtaatgtggaacacagcagtgcactcggaattc
atgcacgatcacgtggattacggctttcaaagctgtgagggtaaattcagttggcatgtc
atcaagcagaaaagggatgcctatgtgagccgcctgaacaccatctatcaaaataattta
accaagtctcacatagaaattatccacggctatgcaacattcgcagatggtcctcggccc
acggtggaagtcaatgggaaaaagtttaccgctccacacatcctgattgccacaggaggc
gtgcccacagttcctcacgagagccagatcccaggcgccagcctggggatcaccagtgat
ggcttctttcagctggaggacttgcccagccgcagcgtcatcgtgggggccgggtacatt
gctgtggagatcgcgggcatcctctctgccctgggctccaagacatctcttatgatcagg
catgataaggtactgagaaattttgattcactcatcagttccaactgcaccgaggaactg
gagaatgccggcgtggaggtgttgaagttcacacaggttaaggaagtaaaaaagacatca
tcaggcctggagctccaagtggtgacttccgtgcctggtaggaagcccaccacgaccatg
attccagatgttgactgcctgctctgggccattggacgggacccaaattctaagggcctg
aatctgaataaagtgggcattcagacggatgaaaagggccacatcctagtagacgaattc
cagaataccaatgtcaaaggcgtctatgctgtgggagacgtctgtgggaaagcgcttctc
accccagttgcaatcgctgctggccggaaacttgcccatagactgtttgaatgcaaacaa
gattccaaattagactatgacaacatccctactgtggtcttcagccacccccctattggg
accgtggggctcactgaagacgaagctgttcataagtatgggaaagacaatgtgaaaatc
tactcgactgcctttaccccgatgtatcacgctgtgaccacgaggaagacgaaatgcgtc
atgaagatggtttgtgccaacaaagaggaaaaggtggttggcattcacatgcaggggatt
ggctgtgatgagatgctgcagggcttcgctgtagcggtgaaaatgggggccaccaaggcc
gacttcgacaacacagttgccattcatcctacctcttcagaggagctggtcaccctgcgc
tga

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