KEGG   Mus musculus (house mouse): 14858
Entry
14858             CDS       T01002                                 
Symbol
Gsta2, Gst2-2, Gstc-2, Gstc2
Name
(RefSeq) glutathione S-transferase, alpha 2 (Yc2)
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00480  Glutathione metabolism
mmu00980  Metabolism of xenobiotics by cytochrome P450
mmu00982  Drug metabolism - cytochrome P450
mmu00983  Drug metabolism - other enzymes
mmu01100  Metabolic pathways
mmu01524  Platinum drug resistance
mmu05200  Pathways in cancer
mmu05204  Chemical carcinogenesis - DNA adducts
mmu05207  Chemical carcinogenesis - receptor activation
mmu05208  Chemical carcinogenesis - reactive oxygen species
mmu05225  Hepatocellular carcinoma
mmu05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    14858 (Gsta2)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    14858 (Gsta2)
   00982 Drug metabolism - cytochrome P450
    14858 (Gsta2)
   00983 Drug metabolism - other enzymes
    14858 (Gsta2)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    14858 (Gsta2)
   05204 Chemical carcinogenesis - DNA adducts
    14858 (Gsta2)
   05207 Chemical carcinogenesis - receptor activation
    14858 (Gsta2)
   05208 Chemical carcinogenesis - reactive oxygen species
    14858 (Gsta2)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    14858 (Gsta2)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    14858 (Gsta2)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    14858 (Gsta2)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:mmu02000]
    14858 (Gsta2)
Enzymes [BR:mmu01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     14858 (Gsta2)
Transporters [BR:mmu02000]
 Other transporters
  Pores ion channels [TC:1]
   14858 (Gsta2)
SSDB
Motif
Pfam: GST_C GST_N GST_C_3 GST_N_2 GST_N_3
Other DBs
NCBI-GeneID: 14858
NCBI-ProteinID: NP_032208
MGI: 95863
Ensembl: ENSMUSG00000057933
UniProt: P10648
Structure
LinkDB
Position
9:complement(78238300..78254474)
AA seq 222 aa
MAGKPVLHYFNARGRMECIRWLLAAAGVEFEEKFIQSPEDLEKLKKDGNLMFDQVPMVEI
DGMKLVQTRAILNYIATKYDLYGKDMKERALIDMYTEGILDLTEMIGQLVLCPPDQREAK
TALAKDRTKNRYLPAFEKVLKSHGQDYLVGNRLTRVDVHLLELLLYVEELDASLLTPFPL
LKAFKSRISSLPNVKKFLHPGSQRKPPLDAKQIEEARKVFKF
NT seq 669 nt   +upstreamnt  +downstreamnt
atggccgggaagcccgtgcttcactacttcaatgcccggggcagaatggagtgcatcagg
tggctcctggctgcagcaggggtggagtttgaagagaagtttatacagagtccggaagat
ttggaaaagctaaaaaaagatgggaatttgatgtttgaccaagtgcccatggtggagatt
gatgggatgaagctggtgcagaccagagccattctcaactacatcgccaccaaatatgac
ctctatgggaaggacatgaaggagagagccctgattgacatgtatacagaaggtatttta
gatctgactgaaatgattgggcaattggtattatgtcccccagaccaaagagaagccaag
actgccttggcaaaagacaggaccaaaaaccgttacttgcctgcctttgaaaaggtgttg
aagagccatggacaagactaccttgtgggcaacaggctgaccagggtggacgtccacctg
ctggaacttcttctctatgttgaagagcttgatgccagccttctgacccctttccctctg
ctgaaggccttcaagagcagaatcagcagcctccccaatgtgaagaagttcctacatcct
ggcagccagagaaagcctcccttggatgcaaaacaaattgaagaagcaaggaaggttttc
aagttttag

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