Mus musculus (house mouse): 15139
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Entry
15139 CDS
T01002
Symbol
Hc, C5, C5a, He, Hfib2
Name
(RefSeq) hemolytic complement
KO
K03994
complement component 5
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04080
Neuroactive ligand-receptor interaction
mmu04610
Complement and coagulation cascades
mmu04613
Neutrophil extracellular trap formation
mmu04810
Regulation of actin cytoskeleton
mmu04936
Alcoholic liver disease
mmu05020
Prion disease
mmu05133
Pertussis
mmu05150
Staphylococcus aureus infection
mmu05168
Herpes simplex virus 1 infection
mmu05171
Coronavirus disease - COVID-19
mmu05322
Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09133 Signaling molecules and interaction
04080 Neuroactive ligand-receptor interaction
15139 (Hc)
09140 Cellular Processes
09142 Cell motility
04810 Regulation of actin cytoskeleton
15139 (Hc)
09150 Organismal Systems
09151 Immune system
04610 Complement and coagulation cascades
15139 (Hc)
04613 Neutrophil extracellular trap formation
15139 (Hc)
09160 Human Diseases
09172 Infectious disease: viral
05171 Coronavirus disease - COVID-19
15139 (Hc)
05168 Herpes simplex virus 1 infection
15139 (Hc)
09171 Infectious disease: bacterial
05133 Pertussis
15139 (Hc)
05150 Staphylococcus aureus infection
15139 (Hc)
09163 Immune disease
05322 Systemic lupus erythematosus
15139 (Hc)
09164 Neurodegenerative disease
05020 Prion disease
15139 (Hc)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
15139 (Hc)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
mmu01002
]
15139 (Hc)
Peptidases and inhibitors [BR:
mmu01002
]
Peptidase inhibitors
Family I39: alpha2M family
15139 (Hc)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
TED_complement
A2M_BRD
C5_CUB
MG1
A2M
NTR
A2M_recep
MG4
MG2
MG3
ANATO
TRAPPC13_C
NOMO_3rd
Motif
Other DBs
NCBI-GeneID:
15139
NCBI-ProteinID:
NP_034536
MGI:
96031
Ensembl:
ENSMUSG00000026874
UniProt:
P06684
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:complement(34873341..34958518)
Genome browser
AA seq
1680 aa
AA seq
DB search
MGLWGILCLLIFLDKTWGQEQTYVISAPKILRVGSSENVVIQVHGYTEAFDATLSLKSYP
DKKVTFSSGYVNLSPENKFQNAALLTLQPNQVPREESPVSHVYLEVVSKHFSKSKKIPIT
YNNGILFIHTDKPVYTPDQSVKIRVYSLGDDLKPAKRETVLTFIDPEGSEVDIVEENDYT
GIISFPDFKIPSNPKYGVWTIKANYKKDFTTTGTAYFEIKEYVLPRFSVSIELERTFIGY
KNFKNFEITVKARYFYNKVVPDAEVYAFFGLREDIKDEEKQMMHKATQAAKLVDGVAQIS
FDSETAVKELSYNSLEDLNNKYLYIAVTVTESSGGFSEEAEIPGVKYVLSPYTLNLVATP
LFVKPGIPFSIKAQVKDSLEQAVGGVPVTLMAQTVDVNQETSDLETKRSITHDTDGVAVF
VLNLPSNVTVLKFEIRTDDPELPEENQASKEYEAVAYSSLSQSYIYIAWTENYKPMLVGE
YLNIMVTPKSPYIDKITHYNYLILSKGKIVQYGTREKLFSSTYQNINIPVTQNMVPSARL
LVYYIVTGEQTAELVADAVWINIEEKCGNQLQVHLSPDEYVYSPGQTVSLDMVTEADSWV
ALSAVDRAVYKVQGNAKRAMQRVFQALDEKSDLGCGAGGGHDNADVFHLAGLTFLTNANA
DDSHYRDDSCKEILRSKRNLHLLRQKIEEQAAKYKHSVPKKCCYDGARVNFYETCEERVA
RVTIGPLCIRAFNECCTIANKIRKESPHKPVQLGRIHIKTLLPVMKADIRSYFPESWLWE
IHRVPKRKQLQVTLPDSLTTWEIQGIGISDNGICVADTLKAKVFKEVFLEMNIPYSVVRG
EQIQLKGTVYNYMTSGTKFCVKMSAVEGICTSGSSAASLHTSRPSRCVFQRIEGSSSHLV
TFTLLPLEIGLHSINFSLETSFGKDILVKTLRVVPEGVKRESYAGVILDPKGIRGIVNRR
KEFPYRIPLDLVPKTKVERILSVKGLLVGEFLSTVLSKEGINILTHLPKGSAEAELMSIA
PVFYVFHYLEAGNHWNIFYPDTLSKRQSLEKKIKQGVVSVMSYRNADYSYSMWKGASAST
WLTAFALRVLGQVAKYVKQDENSICNSLLWLVEKCQLENGSFKENSQYLPIKLQGTLPAE
AQEKTLYLTAFSVIGIRKAVDICPTMKIHTALDKADSFLLENTLPSKSTFTLAIVAYALS
LGDRTHPRFRLIVSALRKEAFVKGDPPIYRYWRDTLKRPDSSVPSSGTAGMVETTAYALL
ASLKLKDMNYANPIIKWLSEEQRYGGGFYSTQDTINAIEGLTEYSLLLKQIHLDMDINVA
YKHEGDFHKYKVTEKHFLGRPVEVSLNDDLVVSTGYSSGLATVYVKTVVHKISVSEEFCS
FYLKIDTQDIEASSHFRLSDSGFKRIIACASYKPSKEESTSGSSHAVMDISLPTGIGANE
EDLRALVEGVDQLLTDYQIKDGHVILQLNSIPSRDFLCVRFRIFELFQVGFLNPATFTVY
EYHRPDKQCTMIYSISDTRLQKVCEGAACTCVEADCAQLQAEVDLAISADSRKEKACKPE
TAYAYKVRITSATEENVFVKYTATLLVTYKTGEAADENSEVTFIKKMSCTNANLVKGKQY
LIMGKEVLQIKHNFSFKYIYPLDSSTWIEYWPTDTTCPSCQAFVENLNNFAEDLFLNSCE
NT seq
5043 nt
NT seq
+upstream
nt +downstream
nt
atgggtctttggggaatactttgtcttttaattttcctggacaaaacttggggacaggaa
caaacctacgtcatttcagcacccaaaatcctccgggtcggctcgtctgaaaatgtggta
attcaagtccatggctacactgaagcatttgatgcaactctttctctaaaaagctatcct
gacaaaaaagtcaccttctcttcaggctatgttaatttgtccccggaaaacaaattccaa
aacgcggcactgttgacactacagcccaatcaagttcctagagaagaaagcccagtctct
cacgtgtatctggaagttgtgtcaaaacacttttcaaaatcaaagaaaataccaattacc
tataacaatggaattctcttcatccatacagacaaacctgtttacacgccggaccagtca
gtaaagatcagagtctattctctgggtgacgacttgaagccagccaaacgggagactgtc
ttaactttcatagaccccgaaggatcagaagttgacattgtagaagaaaatgattacacc
ggaattatctcttttcctgacttcaagattccatctaatcccaagtatggtgtttggaca
attaaagctaactataagaaggattttacaacaactggaactgcatactttgaaattaaa
gaatatgtcttgccacgattctctgtttcaatagaactagaaagaaccttcattggctat
aaaaactttaagaactttgaaatcactgtgaaagcaagatatttttataataaagtggta
cctgatgctgaagtgtatgccttttttggattgagagaggacataaaagatgaggagaag
cagatgatgcacaaagccacacaagccgcaaagttggttgacggagttgctcagatctct
tttgattctgaaacagcagttaaagagctgtcctacaacagtctagaagacttaaacaac
aagtacctttatattgcagtaacagtcacagaatcttcaggtggattttcagaagaggca
gaaatccctggagtcaaatatgtcctctctccctacacactgaatttggtcgctactcct
cttttcgtgaagcccgggattccattttccatcaaggcacaggttaaagattcactcgag
caggcggtaggaggggtcccagtaactctgatggcacaaacagtcgatgtgaatcaagag
acatctgacttggaaacaaagaggagcatcactcatgacactgatggagtagctgtgttt
gtgctgaacctcccatcaaatgtgacggtgctaaagtttgagatcagaactgatgaccca
gaacttcccgaagaaaatcaagccagcaaagagtacgaagcagttgcgtactcgtctctc
agccaaagttacatttacatcgcttggactgaaaactacaagcccatgcttgtgggagaa
tacctgaatattatggttacccccaagagcccatatatcgacaaaataactcactataat
tacttgattttatccaaaggcaaaattgtacagtacggcacaagagagaaacttttctcc
tcaacttatcaaaatataaatattccagtgacacagaacatggttccttcagcacgactc
ctggtctattacatagtcacaggggagcaaacagcagaattagtggctgacgcagtctgg
ataaatattgaggagaagtgtggcaaccagctccaggtccatctgtctccagatgaatat
gtgtattctccaggccaaactgtgtcccttgacatggtgactgaagcagactcatgggta
gcactatcagcagtggacagagctgtgtataaagtccagggaaacgccaaaagggccatg
caaagagtctttcaagctttggatgaaaagagtgacctgggctgtggggcaggtggtggc
catgacaatgcagatgtattccatctagctgggctcaccttcctcaccaacgcaaacgca
gatgactcccattatcgtgatgactcttgtaaagaaattctcaggtcaaagagaaacctg
catctcctaaggcagaaaatagaagaacaagctgctaagtacaaacatagtgtgccaaag
aaatgctgctatgacggagcccgagtgaacttctacgaaacctgtgaggagcgagtggcc
cgggttaccataggccctctctgcatcagggccttcaacgagtgctgtactattgcgaac
aagatccgaaaagaaagcccccataaacctgtccaactgggaaggatccacattaagacc
ctgttaccagtgatgaaggcagatatccgaagctactttccagagagctggctatgggaa
attcatcgcgttcccaaaagaaaacagctgcaggtcacgctgcctgactcactaacgact
tgggaaattcaaggcattggcatttcagacaatggtatatgtgttgctgatacactcaag
gcaaaggtgttcaaagaagtcttcctggagatgaacataccatattctgttgtgcgagga
gaacagatccaattgaaaggaactgtttacaactatatgacctcagggacaaagttctgt
gttaaaatgtctgctgtggaggggatctgcacttcaggaagctcagctgctagccttcac
acctccaggccctccagatgtgtgttccagaggatagagggctcgtccagtcacttggtg
accttcaccctgcttcctctggaaattggccttcactccataaacttctcactagagacc
tcatttgggaaagacatcttagtaaagacattacgggtagtgccagaaggagtcaagagg
gaaagctatgccggcgtgattctggaccctaagggaattcgtggtattgttaacagacga
aaggaattcccatacaggatcccattagatttggtccccaagaccaaagttgaaaggatt
ttgagtgtcaaaggactgcttgtaggggagttcttgtccacggttctgagtaaggaaggc
atcaacatcctaacccacctccccaagggcagtgcagaggcagagctcatgagcatagct
ccggtgttctatgttttccactacctggaagcaggaaaccattggaatattttctatcct
gatacactgagtaaaagacagagcctggagaaaaaaataaaacaaggggtggtgagcgtc
atgtcctacagaaacgctgactattcctacagcatgtggaagggggcgagcgctagtacc
tggctgacagcttttgctctgagagtgcttggacaggtggccaagtatgtaaaacaggat
gaaaactcaatttgtaactctttgctatggctggttgagaagtgtcagctggaaaacggc
tctttcaaggaaaattcccaatatctaccaataaaattacagggtactttgcctgctgaa
gcccaagagaaaactttgtatcttacagccttttctgtgattggaattagaaaggcagtt
gacatatgccccaccatgaaaatccacacagcgctagataaagccgactccttcctgctt
gaaaacaccctgccatccaagagcaccttcacactggccattgtagcctatgctctttcc
ctaggagacagaacccacccgaggtttcgtctaattgtgtcggccctgaggaaggaagct
tttgttaaaggtgatccgcccatttaccgttactggagagataccctcaaacgtccagac
agctctgtgcccagcagcggcacagcaggtatggttgaaaccacagcctatgctttgctc
gccagcctgaaactgaaggatatgaattacgccaaccccatcatcaagtggctatctgaa
gagcagaggtatggaggcggcttttattccacccaggatacgattaatgccatcgagggc
ctgacagaatattcactcctgttaaaacaaattcatttggatatggacatcaatgtcgcc
tacaaacacgaaggtgacttccacaagtataaggtgacagagaagcatttcctggggagg
ccagtggaggtatctctcaatgatgaccttgttgtcagcacaggctacagcagtggcttg
gccacagtatatgtaaaaactgtggttcacaaaattagtgtctctgaggaattttgcagc
ttttacttgaaaattgatacccaagatattgaagcatccagccacttcaggctcagtgac
tctggattcaagcgcataatagcatgtgccagctacaagcccagcaaggaggagtcaaca
tccgggtcctcccatgcagtaatggatatatcactgccgactggaatcggagcaaacgag
gaagatttacgggctcttgtggaaggagtggatcaactactaactgattaccagatcaaa
gatggccatgtcattctgcaactgaattcgatcccctccagagatttcctctgtgtccgg
ttccggatatttgaacttttccaagttgggtttctgaatcctgctaccttcacggtgtac
gagtatcacagaccagataagcagtgcaccatgatttatagcatttctgacaccaggctt
cagaaagtctgtgaaggagcagcttgcacatgtgtggaagctgactgtgcgcaactgcag
gcagaagtagacctagccatctctgcagactccagaaaagagaaagcctgtaaaccagag
actgcatatgcttataaagtcaggatcacatcagccactgaagaaaatgtttttgtcaag
tacactgcgactcttctggtcacttacaaaacaggggaagctgctgatgagaattcggag
gtcaccttcattaaaaagatgagctgtaccaatgccaacctggtgaaagggaagcagtat
ttaatcatgggcaaagaggttctgcagatcaaacacaatttcagtttcaagtatatatac
cctctagattcctccacctggattgaatattggcccacagacacaacgtgtccatcctgt
caagcatttgtagagaatttgaataactttgctgaagacctctttttaaacagctgtgaa
tga
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