Mus musculus (house mouse): 15194
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Entry
15194 CDS
T01002
Symbol
Htt, C430023I11Rik, Hd, Hdh, IT15
Name
(RefSeq) huntingtin
KO
K04533
huntingtin
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu05016
Huntington disease
mmu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05016 Huntington disease
15194 (Htt)
05022 Pathways of neurodegeneration - multiple diseases
15194 (Htt)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03019 Messenger RNA biogenesis [BR:
mmu03019
]
15194 (Htt)
04131 Membrane trafficking [BR:
mmu04131
]
15194 (Htt)
03029 Mitochondrial biogenesis [BR:
mmu03029
]
15194 (Htt)
Messenger RNA biogenesis [BR:
mmu03019
]
Eukaryotic type
mRNA surveillance and transport factors
mRNA cycle factors
Common to processing body (P body) and stress granule
15194 (Htt)
Membrane trafficking [BR:
mmu04131
]
Endocytosis
Rab GTPases and associated proteins
Rab associated proteins
15194 (Htt)
Mitochondrial biogenesis [BR:
mmu03029
]
Mitochondrial quality control factors
Regulator of mitochondrial biogenesis
Other regulator of mitochondrial biogenesis
15194 (Htt)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Htt_C-HEAT
Htt_N-HEAT
Htt_bridge
Htt_N-HEAT_1
HEAT
HEAT_EF3_N
Death_3
Motif
Other DBs
NCBI-GeneID:
15194
NCBI-ProteinID:
NP_034544
MGI:
96067
Ensembl:
ENSMUSG00000029104
UniProt:
G3X9H5
LinkDB
All DBs
Position
5:34919084..35069878
Genome browser
AA seq
3120 aa
AA seq
DB search
MATLEKLMKAFESLKSFQQQQQQQPPPQAPPPPPPPPPPQPPQPPPQGQPPPPPPPLPGP
AEEPLHRPKKELSATKKDRVNHCLTICENIVAQSLRNSPEFQKLLGIAMELFLLCSDDAE
SDVRMVADECLNKVIKALMDSNLPRLQLELYKEIKKNGAPRSLRAALWRFAELAHLVRPQ
KCRPYLVNLLPCLTRTSKRPEESVQETLAAAVPKIMASFGNFANDNEIKVLLKAFIANLK
SSSPTVRRTAAGSAVSICQHSRRTQYFYNWLLNVLLGLLVPMEEEHSTLLILGVLLTLRC
LVPLLQQQVKDTSLKGSFGVTRKEMEVSPSTEQLVQVYELTLHHTQHQDHNVVTGALELL
QQLFRTPPPELLQALTTPGGLGQLTLVQEEARGRGRSGSIVELLAGGGSSCSPVLSRKQK
GKVLLGEEEALEDDSESRSDVSSSAFAASVKSEIGGELAASSGVSTPGSVGHDIITEQPR
SQHTLQADSVDLSGCDLTSAATDGDEEDILSHSSSQFSAVPSDPAMDLNDGTQASSPISD
SSQTTTEGPDSAVTPSDSSEIVLDGADSQYLGMQIGQPQEDDEEGAAGVLSGEVSDVFRN
SSLALQQAHLLERMGHSRQPSDSSIDKYVTRDEVAEASDPESKPCRIKGDIGQPNDDDSA
PLVHCVRLLSASFLLTGEKKALVPDRDVRVSVKALALSCIGAAVALHPESFFSRLYKVPL
NTTESTEEQYVSDILNYIDHGDPQVRGATAILCGTLVYSILSRSRLRVGDWLGNIRTLTG
NTFSLVDCIPLLQKTLKDESSVTCKLACTAVRHCVLSLCSSSYSDLGLQLLIDMLPLKNS
SYWLVRTELLDTLAEIDFRLVSFLEAKAESLHRGAHHYTGFLKLQERVLNNVVIYLLGDE
DPRVRHVAATSLTRLVPKLFYKCDQGQADPVVAVARDQSSVYLKLLMHETQPPSHFSVST
ITRIYRGYSLLPSITDVTMENNLSRVVAAVSHELITSTTRALTFGCCEALCLLSAAFPVC
TWSLGWHCGVPPLSASDESRKSCTVGMASMILTLLSSAWFPLDLSAHQDALILAGNLLAA
SAPKSLRSSWTSEEEANSAATRQEEIWPALGDRTLVPLVEQLFSHLLKVINICAHVLDDV
TPGPAIKAALPSLTNPPSLSPIRRKGKEKEPGEQASTPMSPKKVGEASAASRQSDTSGPV
TASKSSSLGSFYHLPSYLKLHDVLKATHANYKVTLDLQNSTEKFGGFLRSALDVLSQILE
LATLQDIGKCVEEVLGYLKSCFSREPMMATVCVQQLLKTLFGTNLASQFDGLSSNPSKSQ
CRAQRLGSSSVRPGLYHYCFMAPYTHFTQALADASLRNMVQAEQERDASGWFDVLQKVSA
QLKTNLTSVTKNRADKNAIHNHIRLFEPLVIKALKQYTTTTSVQLQKQVLDLLAQLVQLR
VNYCLLDSDQVFIGFVLKQFEYIEVGQFRESEAIIPNIFFFLVLLSYERYHSKQIIGIPK
IIQLCDGIMASGRKAVTHAIPALQPIVHDLFVLRGTNKADAGKELETQKEVVVSMLLRLI
QYHQVLEMFILVLQQCHKENEDKWKRLSRQVADIILPMLAKQQMHIDSHEALGVLNTLFE
ILAPSSLRPVDMLLRSMFITPSTMASVSTVQLWISGILAILRVLISQSTEDIVLCRIQEL
SFSPHLLSCPVINRLRGGGGNVTLGECSEGKQKSLPEDTFSRFLLQLVGILLEDIVTKQL
KVDMSEQQHTFYCQELGTLLMCLIHIFKSGMFRRITAAATRLFTSDGCEGSFYTLESLNA
RVRSMVPTHPALVLLWCQILLLINHTDHRWWAEVQQTPKRHSLSCTKSLNPQKSGEEEDS
GSAAQLGMCNREIVRRGALILFCDYVCQNLHDSEHLTWLIVNHIQDLISLSHEPPVQDFI
SAIHRNSAASGLFIQAIQSRCENLSTPTTLKKTLQCLEGIHLSQSGAVLTLYVDRLLGTP
FRALARMVDTLACRRVEMLLAANLQSSMAQLPEEELNRIQEHLQNSGLAQRHQRLYSLLD
RFRLSTVQDSLSPLPPVTSHPLDGDGHTSLETVSPDKDWYLQLVRSQCWTRSDSALLEGA
ELVNRIPAEDMNDFMMSSEFNLSLLAPCLSLGMSEIANGQKSPLFEAARGVILNRVTSVV
QQLPAVHQVFQPFLPIEPTAYWNKLNDLLGDTTSYQSLTILARALAQYLVVLSKVPAHLH
LPPEKEGDTVKFVVMTVEALSWHLIHEQIPLSLDLQAGLDCCCLALQVPGLWGVLSSPEY
VTHACSLIHCVRFILEAIAVQPGDQLLGPESRSHTPRAVRKEEVDSDIQNLSHVTSACEM
VADMVESLQSVLALGHKRNSTLPSFLTAVLKNIVISLARLPLVNSYTRVPPLVWKLGWSP
KPGGDFGTVFPEIPVEFLQEKEILKEFIYRINTLGWTNRTQFEETWATLLGVLVTQPLVM
EQEESPPEEDTERTQIHVLAVQAITSLVLSAMTVPVAGNPAVSCLEQQPRNKPLKALDTR
FGRKLSMIRGIVEQEIQEMVSQRENTATHHSHQAWDPVPSLLPATTGALISHDKLLLQIN
PEREPGNMSYKLGQVSIHSVWLGNNITPLREEEWDEEEEEESDVPAPTSPPVSPVNSRKH
RAGVDIHSCSQFLLELYSRWILPSSAARRTPVILISEVVRSLLVVSDLFTERTQFEMMYL
TLTELRRVHPSEDEILIQYLVPATCKAAAVLGMDKTVAEPVSRLLESTLRSSHLPSQIGA
LHGILYVLECDLLDDTAKQLIPVVSDYLLSNLKGIAHCVNIHSQQHVLVMCATAFYLMEN
YPLDVGPEFSASVIQMCGVMLSGSEESTPSIIYHCALRGLERLLLSEQLSRLDTESLVKL
SVDRVNVQSPHRAMAALGLMLTCMYTGKEKASPGRASDPSPATPDSESVIVAMERVSVLF
DRIRKGFPCEARVVARILPQFLDDFFPPQDVMNKVIGEFLSNQQPYPQFMATVVYKVFQT
LHSAGQSSMVRDWVMLSLSNFTQRTPVAMAMWSLSCFLVSASTSPWVSAILPHVISRMGK
LEQVDVNLFCLVATDFYRHQIEEEFDRRAFQSVFEVVAAPGSPYHRLLACLQNVHKVTTC
NT seq
9363 nt
NT seq
+upstream
nt +downstream
nt
atggcaaccctggaaaagctgatgaaggctttcgagtcgctcaagtcgtttcagcagcaa
cagcagcagcagccaccgccgcaggcgccgccgccaccgccgccgccgcctccgcctcaa
ccccctcagccgccgcctcaggggcagccgccgccgccaccaccgccgctgccaggtccg
gcagaggaaccgctgcaccgaccaaagaaggaactctcagccaccaagaaagaccgtgtg
aatcattgtctaacaatatgtgaaaacattgtggcacagtctctcagaaattctccagaa
tttcagaaactcttgggcatcgctatggaactgtttctgctgtgcagtgacgatgcggag
tcagatgtcagaatggtggctgatgagtgcctcaacaaagtcatcaaagctttgatggat
tctaatcttccaaggctacagttagaactctataaggaaattaaaaagaatggtgctcct
cgaagtttgcgtgctgccctgtggaggtttgctgagctggctcacctggttcgacctcag
aagtgcaggccttacctggtgaatcttcttccatgcctgacccgaacaagcaaaagaccg
gaggaatcagttcaggagaccttggctgcagctgttcctaaaattatggcttcttttggc
aatttcgcaaatgacaatgaaattaaggttctgttgaaagctttcatagcaaatctgaag
tcaagctctcccaccgtgcggcggacagcagccggctcagccgtgagcatctgccaacat
tctaggaggacacagtacttctacaactggctccttaatgtcctcctaggtctgctggtt
cccatggaagaagagcactccactctcctgatcctcggtgtgttgctcacattgaggtgt
ctagtgcccttgctccagcagcaggtcaaggacacaagtctaaaaggcagctttggggtg
acacggaaagaaatggaagtctctccttctacagagcagcttgtccaggtttatgaactg
actttgcatcatactcagcaccaagaccacaatgtggtgacaggggcactggagctcctg
cagcagctcttccgtacccctccacctgaactcctgcaagcactgaccacaccaggaggg
cttgggcagctcactctggttcaagaagaggcccggggccgaggccgcagcgggagcatc
gtggagcttttagctggagggggttcctcgtgcagccctgtcctctcaagaaagcagaaa
ggcaaagtgctcttaggagaggaagaagccttggaagatgactcggagtccaggtcagat
gtcagcagctcagcctttgcagcctctgtgaagagtgagattggtggagagctcgctgct
tcttcaggtgtttccactcctggttctgttggtcacgacatcatcactgagcagcctaga
tcccagcacacacttcaagcagactctgtggatttgtccggctgtgacctgaccagtgct
gctactgatggggatgaggaggacatcttgagccacagctccagccagttcagtgctgtc
ccatccgaccctgccatggacctgaatgatgggacccaggcctcctcacccatcagtgac
agttctcagaccaccactgaaggacctgattcagctgtgactccttcggacagttctgaa
attgtgttagatggtgccgatagccagtatttaggcatgcagataggacagccacaggag
gacgatgaggagggagctgcaggtgttctttctggtgaagtctcagatgttttcagaaac
tcttctctggcccttcaacaggcacacttgttggaaagaatgggccatagcaggcagcct
tccgacagcagtatagataagtatgtaacaagagatgaggttgctgaagccagtgatcca
gaaagcaagccttgccgaatcaaaggtgacataggacagcctaatgatgatgattctgct
cctctggtacattgtgtccgtcttttatctgcttcctttttgttaactggtgaaaagaaa
gcactggttccagacagagacgtgagagtcagtgtgaaggccctggccctcagctgcatt
ggtgcggctgtggcccttcatccagagtcgttcttcagcagactgtacaaagtacctctt
aataccacggaaagtactgaggaacagtatgtttctgacatcttgaactacatcgatcat
ggagacccacaggtccgaggagctactgccattctctgtgggacccttgtctactccatc
ctcagtaggtcccgtctccgtgttggtgactggctgggcaacatcagaaccctgacagga
aatacattttctctggtggactgcattcctttactgcagaaaacgttgaaggatgaatct
tctgttacttgcaagttggcttgtacagctgtgaggcactgtgtcctgagtctttgcagc
agcagctacagtgacttgggattacaactgcttattgatatgctgcctctgaagaacagc
tcctactggctggtgaggaccgaactgctggacactctggcagagattgacttcaggctc
gtgagttttttggaggcaaaagcagaaagtttacaccgaggggctcatcattatacaggg
tttctaaaactacaagaacgagtactcaataatgtggtcatttatttgcttggagatgaa
gaccccagggttcgacatgttgctgcaacatcattaacaaggcttgtcccaaagctgttt
tacaagtgtgaccaaggacaagctgatccagttgtggctgtagcgagggatcagagcagt
gtctacctgaagctcctcatgcatgagacccagccaccatcacacttttctgtcagcacc
atcaccagaatctatagaggctatagcttactgccaagtataacagatgtcaccatggaa
aacaatctctcaagagttgttgccgcagtttctcatgaactcattacgtcaacaacacgg
gcactcacatttggatgctgtgaagccttgtgtcttctctcagcagcctttccagtttgc
acttggagtttaggatggcactgtggagtgcccccactgagtgcctctgatgagtccagg
aagagctgcactgttgggatggcctccatgattctcaccttgctttcatcagcttggttc
ccactggatctctcagcccatcaggatgccttgattttggctggaaacttgctagcagcg
agtgcccccaagtctctgagaagttcatggacctctgaagaagaagccaactcagcagcc
accagacaggaggaaatctggcctgctctgggggatcggactctagtgcccttggtggag
cagcttttctcccacctgctgaaggtgatcaatatctgtgctcatgtcttggacgatgtg
actcctggaccagcaatcaaggcagccttgccttctctaacaaaccccccttctctaagt
cctattcgacggaaagggaaggagaaagaacctggagaacaagcttctactccaatgagt
cccaagaaagttggtgaggccagtgcagcctctcgacaatcagacacctcaggacctgtc
acagcaagtaaatcatcctcactggggagtttctaccatctcccctcctacctcaaactg
catgatgtcctgaaagccactcacgccaactataaggtcaccttagatcttcagaacagc
actgaaaagtttggggggttcctgcgctctgccttggacgtcctttctcagattctagag
ctggcgacactgcaggacattggaaagtgtgttgaagaggtccttggatacctgaaatcc
tgctttagtcgagaaccaatgatggcaactgtctgtgtgcagcagctattgaagactctc
tttgggacaaacttagcctcacagtttgatggcttatcttccaaccccagcaagtctcag
tgccgagctcagcgccttggctcttcaagtgtgaggcccggcttatatcactactgcttc
atggcaccatacacgcacttcacacaggccttggctgacgcaagcctgaggaacatggtg
caggcggagcaggagcgtgatgcctcggggtggtttgatgtactccagaaagtgtctgcc
caattgaagacgaacctaacaagcgtcacaaagaaccgtgcagataagaatgctattcat
aatcacattaggttatttgagcctcttgttataaaagcattgaagcagtacaccacgaca
acatctgtacaattgcagaagcaggttttggatttgctggcacagctggttcagctacgg
gtcaattactgtctactggattcagaccaggtgttcatcgggtttgtgctgaagcagttt
gagtacattgaagtgggccagttcagggaatcagaggcaattattccaaatatatttttc
ttcctggtattactgtcttatgagcgctaccattcaaaacagatcattggaattcctaaa
atcatccagctgtgtgatggcatcatggccagtggaaggaaggccgttacacatgctata
cctgctctgcagcccattgtccatgacctctttgtgttacgaggaacaaataaagctgat
gcagggaaagagcttgagacacagaaggaggtggtggtctccatgctgttacgactcatc
cagtaccatcaggtgctggagatgttcatccttgtcctgcagcagtgccacaaggagaat
gaggacaagtggaaacggctctctcggcaggtcgcagacatcatcctgcccatgttggcc
aagcagcagatgcatattgactctcatgaagcccttggagtgttaaataccttgtttgag
attttggctccttcctccctacgtcctgtggacatgcttttgcggagtatgttcatcact
ccaagcacaatggcatctgtaagcactgtgcagctgtggatatctggaatcctcgccatt
ctgagggttctcatttcccagtcaaccgaggacattgttctttgtcgtattcaggagctc
tccttctctccacacttgctctcctgtccagtgattaacaggttaaggggtggaggcggt
aatgtaacactaggagaatgcagcgaagggaaacaaaagagtttgccagaagatacattc
tcaaggtttcttttacagctggttggtattcttctagaagacatcgttacaaaacagctc
aaagtggacatgagtgaacagcagcatacgttctactgccaagagctaggcacactgctc
atgtgtctgatccacatattcaaatctggaatgttccggagaatcacagcagctgccact
agactcttcaccagtgatggctgtgaaggcagcttctatactctagagagcctgaatgca
cgggtccgatccatggtgcccacgcacccagccctggtactgctctggtgtcagatccta
cttctcatcaaccacactgaccaccggtggtgggcagaggtgcagcagacacccaagaga
cacagtctgtcctgcacgaagtcacttaacccccagaagtctggcgaagaggaggattct
ggctcggcagctcagctgggaatgtgcaatagagaaatagtgcgaagaggggcccttatt
ctcttctgtgattatgtctgtcagaatctccatgactcagaacacttaacatggctcatt
gtgaatcacattcaagatctgatcagcttgtctcatgagcctccagtacaagactttatt
agtgccattcatcgtaattctgcagctagtggtctttttatccaggcaattcagtctcgc
tgtgaaaatctttcaacgccaaccactctgaagaaaacacttcagtgcttggaaggcatc
catctcagccagtctggtgctgtgctcacactatatgtggacaggctcctgggcaccccc
ttccgtgcgctggctcgcatggtcgacaccctggcctgtcgccgggtagaaatgcttttg
gctgcaaatttacagagcagcatggcccagttgccagaggaggaactaaacagaatccaa
gaacacctccagaacagtgggcttgcacaaagacaccaaaggctctattcactgctggac
agattccgactctctactgtgcaggactcacttagccccttgcccccagtcacttcccac
ccactggatggggatgggcacacatctctggaaacagtgagtccagacaaagactggtac
ctccagcttgtcagatcccagtgttggaccagatcagattctgcactgctggaaggtgca
gagctggtcaaccgtatccctgctgaagatatgaatgacttcatgatgagctcggagttc
aacctaagccttttggctccctgtttaagccttggcatgagcgagattgctaatggccaa
aagagtcccctctttgaagcagcccgtggggtgattctgaaccgggtgaccagtgttgtt
cagcagcttcctgctgtccatcaagtcttccagcccttcctgcctatagagcccacggcc
tactggaacaagttgaatgatctgcttggtgataccacatcataccagtctctgaccata
cttgcccgtgccctggcacagtacctggtggtgctctccaaagtgcctgctcatttgcac
cttcctcctgagaaggagggggacacggtgaagtttgtggtaatgacagttgaggccctg
tcatggcatttgatccatgagcagatcccactgagtctggacctccaagccgggctagac
tgctgctgcctggcactacaggtgcctggcctctggggggtgctgtcctccccagagtac
gtgactcatgcctgctccctcatccattgtgtgcgattcatcctggaagccattgcagta
caacctggagaccagcttctcggtcctgaaagcaggtcacatactccaagagctgtcaga
aaggaggaagtagactcagatatacaaaacctcagtcatgtcacttcggcctgcgagatg
gtggcagacatggtggaatccctgcagtcagtgctggccttgggccacaagaggaacagc
accctgccttcatttctcacagctgtgctgaagaacattgttatcagtctggcccgactc
cccctagttaacagctatactcgtgtgcctcctctggtatggaaactcgggtggtcaccc
aagcctggaggggattttggcacagtgtttcctgagatccctgtagagttcctccaggag
aaggagatcctcaaggagttcatctaccgcatcaacaccctagggtggaccaatcgtacc
cagttcgaagaaacttgggccaccctccttggtgtcctggtgactcagcccctggtgatg
gaacaggaagagagcccaccagaggaagacacagaaagaacccagatccatgtcctggct
gtgcaggccatcacctctctagtgctcagtgcaatgaccgtgcctgtggctggcaatcca
gctgtaagctgcttggagcaacagccccggaacaagccactgaaggctctcgataccaga
tttggaagaaagctgagcatgatcagagggattgtagaacaagaaatccaagagatggtt
tcccagagagagaatactgccactcaccattctcaccaggcgtgggatcctgtcccttct
ctgttaccagctactacaggtgctcttatcagccatgacaagctgctgctgcagatcaac
ccagagcgggagccaggcaacatgagctacaagctgggccaggtgtccatacactccgtg
tggctgggaaataacatcacacccctgagagaggaggaatgggatgaggaagaagaggaa
gaaagtgatgtccctgcaccaacgtcaccacctgtgtctccagtcaattccagaaaacac
cgtgccggggttgatattcactcctgttcgcagtttctgcttgaattgtacagccgatgg
atcctgccatccagtgcagccagaaggacccccgtcatcctgatcagtgaagtggttcga
tctcttcttgtagtgtcagacttattcaccgaacgtacccagtttgaaatgatgtatctg
acgctgacagaactacggagagtgcacccttcagaagatgagatcctcattcagtacctg
gtgcctgccacctgtaaggcagctgctgtccttggaatggacaaaactgtggcagagcca
gtcagccgcctactggagagcacactgaggagcagccacctgcccagccagatcggagcc
ctgcacggcatcctctatgtgttggagtgtgacctcttggatgacactgcaaagcagctc
attccagttgttagtgactatctgctgtccaacctcaaaggaatagcccactgcgtgaac
attcacagccagcagcatgtgctggtaatgtgtgccactgctttctacctgatggaaaac
taccctctggatgtgggaccagaattttcagcatctgtgatacagatgtgtggagtaatg
ctgtctggaagtgaggagtccaccccctccatcatttaccactgtgccctccggggtctg
gagcggctcctgctgtctgagcagctatctcggctagacacagagtccttggtcaagcta
agtgtggacagagtgaatgtacaaagcccacacagggccatggcagccctaggcctgatg
ctcacctgcatgtacacaggaaaggaaaaagccagtccaggcagagcttctgaccccagc
cctgctacacctgacagcgagtctgtgattgtagctatggagcgagtgtctgttctcttt
gataggatccgcaagggatttccctgtgaagccagggttgtggcaaggatcctgcctcag
ttcctagatgacttctttccacctcaagatgtcatgaacaaagtcattggagagttcctg
tccaatcagcagccatacccacagttcatggccactgtagtttacaaggtttttcagact
ctgcacagtgctgggcagtcatccatggtccgggactgggtcatgctgtccctgtccaac
ttcacacaaagaactccagttgccatggccatgtggagcctctcctgcttccttgttagc
gcatctaccagcccatgggtttctgcgatccttccacatgtcatcagcaggatgggcaaa
ctggaacaggtggatgtgaaccttttctgcctggttgccacagacttctacagacaccag
atagaggaggaattcgaccgcagggctttccagtctgtgtttgaggtggtggctgcacca
ggaagtccataccacaggctgcttgcttgtttgcaaaatgttcacaaggtcaccacctgc
tga
DBGET
integrated database retrieval system
