Mus musculus (house mouse): 15251
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Entry
15251 CDS
T01002
Symbol
Hif1a, HIF-1-alpha, HIF1-alpha, HIF1alpha, MOP1, bHLHe78
Name
(RefSeq) hypoxia inducible factor 1, alpha subunit
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04066
HIF-1 signaling pathway
mmu04137
Mitophagy - animal
mmu04140
Autophagy - animal
mmu04148
Efferocytosis
mmu04659
Th17 cell differentiation
mmu04919
Thyroid hormone signaling pathway
mmu05167
Kaposi sarcoma-associated herpesvirus infection
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05208
Chemical carcinogenesis - reactive oxygen species
mmu05211
Renal cell carcinoma
mmu05230
Central carbon metabolism in cancer
mmu05231
Choline metabolism in cancer
mmu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
15251 (Hif1a)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
15251 (Hif1a)
04137 Mitophagy - animal
15251 (Hif1a)
04148 Efferocytosis
15251 (Hif1a)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
15251 (Hif1a)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
15251 (Hif1a)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
15251 (Hif1a)
05205 Proteoglycans in cancer
15251 (Hif1a)
05208 Chemical carcinogenesis - reactive oxygen species
15251 (Hif1a)
05230 Central carbon metabolism in cancer
15251 (Hif1a)
05231 Choline metabolism in cancer
15251 (Hif1a)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
15251 (Hif1a)
09162 Cancer: specific types
05211 Renal cell carcinoma
15251 (Hif1a)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
15251 (Hif1a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
mmu03000
]
15251 (Hif1a)
Transcription factors [BR:
mmu03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
15251 (Hif1a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
bHLH_HIF1A
PAS_3
PAS_11
HIF-1a_CTAD
PAS
HIF-1
PAS_9
PAS_4
HLH
Motif
Other DBs
NCBI-GeneID:
15251
NCBI-ProteinID:
NP_034561
MGI:
106918
Ensembl:
ENSMUSG00000021109
UniProt:
Q61221
Q3UCW2
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:73948186..73994304
Genome browser
AA seq
836 aa
AA seq
DB search
MEGAGGENEKKKMSSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGGLDSEDEMKAQMDCFYLKALDGFVMVLTDDGDMVYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVRKGKELNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTESV
LKPVESSDMKMTQLFTKVESEDTSCLFDKLKKEPDALTLLAPAAGDTIISLDFGSDDTET
EDQQLEDVPLYNDVMFPSSNEKLNINLAMSPLPSSETPKPLRSSADPALNQEVALKLESS
PESLGLSFTMPQIQDQPASPSDGSTRQSSPERLLQENVNTPNFSQPNSPSEYCFDVDSDM
VNVFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESNS
PSPPSMSTVTGFQQTQLQKPTITATATTTATTDESKTETKDNKEDIKILIASPSSTQVPQ
ETTTAKASAYSGTHSRTASPDRAGKRVIEQTDKAHPRSLNLSATLNQRNTVPEEELNPKT
IASQNAQRKRKMEHDGSLFQAAGIGTLLQQPGDCAPTMSLSWKRVKGFISSEQNGTEQKT
IILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2511 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgagaacgagaagaaaaagatgagttctgaacgtcgaaaagaa
aagtctagagatgcagcaagatctcggcgaagcaaagagtctgaagttttttatgagctt
gctcatcagttgccacttccccacaatgtgagctcacatcttgataaagcttctgttatg
aggctcaccatcagttatttacgtgtgagaaaacttctggatgccggtggtctagacagt
gaagatgagatgaaggcacagatggactgtttttatctgaaagccctagatggctttgtg
atggtgctaacagatgacggcgacatggtttacatttctgataacgtgaacaaatacatg
gggttaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaggaaatgagagaaatgcttacacacagaaatggcccagtgagaaaagggaaagaa
ctaaacacacagcggagcttttttctcagaatgaagtgcaccctaacaagccgggggagg
acgatgaacatcaagtcagcaacgtggaaggtgcttcactgcacgggccatattcatgtc
tatgataccaacagtaaccaacctcagtgtgggtacaagaaaccacccatgacgtgcttg
gtgctgatttgtgaacccattcctcatccgtcaaatattgaaattcctttagatagcaag
acatttctcagtcgacacagcctcgatatgaaattttcttactgtgatgaaagaattact
gagttgatgggttatgagccggaagaacttttgggccgctcaatttatgaatattatcat
gctttggattctgatcatctgaccaaaactcaccatgatatgtttactaaaggacaagtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcaactgtcatatataatacgaagaactcccagccacagtgcattgtgtgtgtgaattat
gttgtaagtggtattattcagcacgacttgattttctcccttcaacaaacagaatctgtg
ctcaaaccagttgaatcttcagatatgaagatgactcagctgttcaccaaagttgaatca
gaggatacaagctgcctttttgataagcttaagaaggagcctgatgctctcactctgctg
gctccagctgccggcgacaccatcatctctctggattttggcagcgatgacacagaaact
gaagatcaacaacttgaagatgttccattatataatgatgtaatgtttccctcttctaat
gaaaaattaaatataaacctggcaatgtctcctttaccttcatcggaaactccaaagcca
cttcgaagtagtgctgatcctgcactgaatcaagaggttgcattaaaattagaatcaagt
ccagagtcactgggactttcttttaccatgccccagattcaagatcagccagcaagtcct
tctgatggaagcactagacaaagttcacctgagagacttcttcaggaaaacgtaaacact
cctaacttttcccagcctaacagtcccagtgaatattgctttgatgtggatagcgatatg
gtcaatgtattcaagttggaactggtggaaaaactgtttgctgaagacacagaggcaaag
aatccattttcaactcaggacactgatttagatttggagatgctggctccctatatccca
atggatgatgatttccagttacgttcctttgatcagttgtcaccattagagagcaattct
ccaagccctccaagtatgagcacagttactgggttccagcagacccagttacagaaacct
accatcactgccactgccaccacaactgccaccactgatgaatcaaaaacagagacgaag
gacaataaagaagatattaaaatactgattgcatctccatcttctacccaagtacctcaa
gaaacgaccactgctaaggcatcagcatacagtggcactcacagtcggacagcctcacca
gacagagcaggaaagagagtcatagaacagacagacaaagctcatccaaggagccttaac
ctgtctgccactttgaatcaaagaaatactgttcctgaggaagaattaaacccaaagaca
atagcttcgcagaatgctcagaggaagcgaaaaatggaacatgatggctccctttttcaa
gcagcaggaattggaacattattgcagcaaccaggtgactgtgcacctactatgtcactt
tcctggaaacgagtgaaaggattcatatctagtgaacagaatggaacggagcaaaagact
attattttaataccctccgatttagcatgcagactgctggggcagtcaatggatgagagt
ggattaccacagctgaccagttacgattgtgaagttaatgctcccatacaaggcagcaga
aacctactgcagggtgaagaattactcagagctttggatcaagttaactga
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