Mus musculus (house mouse): 15251
Help
Entry
15251 CDS
T01002
Symbol
Hif1a, AA959795, HIF-1-alpha, HIF1-alpha, HIF1alpha, MOP1, bHLHe78
Name
(RefSeq) hypoxia inducible factor 1, alpha subunit
KO
K08268
hypoxia-inducible factor 1 alpha
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04066
HIF-1 signaling pathway
mmu04137
Mitophagy - animal
mmu04140
Autophagy - animal
mmu04659
Th17 cell differentiation
mmu04919
Thyroid hormone signaling pathway
mmu05167
Kaposi sarcoma-associated herpesvirus infection
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05208
Chemical carcinogenesis - reactive oxygen species
mmu05211
Renal cell carcinoma
mmu05230
Central carbon metabolism in cancer
mmu05231
Choline metabolism in cancer
mmu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
15251 (Hif1a)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
15251 (Hif1a)
04137 Mitophagy - animal
15251 (Hif1a)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
15251 (Hif1a)
09152 Endocrine system
04919 Thyroid hormone signaling pathway
15251 (Hif1a)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
15251 (Hif1a)
05205 Proteoglycans in cancer
15251 (Hif1a)
05208 Chemical carcinogenesis - reactive oxygen species
15251 (Hif1a)
05230 Central carbon metabolism in cancer
15251 (Hif1a)
05231 Choline metabolism in cancer
15251 (Hif1a)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
15251 (Hif1a)
09162 Cancer: specific types
05211 Renal cell carcinoma
15251 (Hif1a)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
15251 (Hif1a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03000 Transcription factors [BR:
mmu03000
]
15251 (Hif1a)
Transcription factors [BR:
mmu03000
]
Eukaryotic type
Basic helix-loop-helix (bHLH)
Factors with PAS domain
15251 (Hif1a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PAS_3
HIF-1a_CTAD
PAS_11
PAS
HIF-1
PAS_9
PAS_4
HLH
Motif
Other DBs
NCBI-GeneID:
15251
NCBI-ProteinID:
NP_034561
MGI:
106918
Ensembl:
ENSMUSG00000021109
UniProt:
Q61221
Q3UCW2
Structure
PDB
LinkDB
All DBs
Position
12:73948098..73994328
Genome browser
AA seq
836 aa
AA seq
DB search
MEGAGGENEKKKMSSERRKEKSRDAARSRRSKESEVFYELAHQLPLPHNVSSHLDKASVM
RLTISYLRVRKLLDAGGLDSEDEMKAQMDCFYLKALDGFVMVLTDDGDMVYISDNVNKYM
GLTQFELTGHSVFDFTHPCDHEEMREMLTHRNGPVRKGKELNTQRSFFLRMKCTLTSRGR
TMNIKSATWKVLHCTGHIHVYDTNSNQPQCGYKKPPMTCLVLICEPIPHPSNIEIPLDSK
TFLSRHSLDMKFSYCDERITELMGYEPEELLGRSIYEYYHALDSDHLTKTHHDMFTKGQV
TTGQYRMLAKRGGYVWVETQATVIYNTKNSQPQCIVCVNYVVSGIIQHDLIFSLQQTESV
LKPVESSDMKMTQLFTKVESEDTSCLFDKLKKEPDALTLLAPAAGDTIISLDFGSDDTET
EDQQLEDVPLYNDVMFPSSNEKLNINLAMSPLPSSETPKPLRSSADPALNQEVALKLESS
PESLGLSFTMPQIQDQPASPSDGSTRQSSPERLLQENVNTPNFSQPNSPSEYCFDVDSDM
VNVFKLELVEKLFAEDTEAKNPFSTQDTDLDLEMLAPYIPMDDDFQLRSFDQLSPLESNS
PSPPSMSTVTGFQQTQLQKPTITATATTTATTDESKTETKDNKEDIKILIASPSSTQVPQ
ETTTAKASAYSGTHSRTASPDRAGKRVIEQTDKAHPRSLNLSATLNQRNTVPEEELNPKT
IASQNAQRKRKMEHDGSLFQAAGIGTLLQQPGDCAPTMSLSWKRVKGFISSEQNGTEQKT
IILIPSDLACRLLGQSMDESGLPQLTSYDCEVNAPIQGSRNLLQGEELLRALDQVN
NT seq
2511 nt
NT seq
+upstream
nt +downstream
nt
atggagggcgccggcggcgagaacgagaagaaaaagatgagttctgaacgtcgaaaagaa
aagtctagagatgcagcaagatctcggcgaagcaaagagtctgaagttttttatgagctt
gctcatcagttgccacttccccacaatgtgagctcacatcttgataaagcttctgttatg
aggctcaccatcagttatttacgtgtgagaaaacttctggatgccggtggtctagacagt
gaagatgagatgaaggcacagatggactgtttttatctgaaagccctagatggctttgtg
atggtgctaacagatgacggcgacatggtttacatttctgataacgtgaacaaatacatg
gggttaactcagtttgaactaactggacacagtgtgtttgattttactcatccatgtgac
catgaggaaatgagagaaatgcttacacacagaaatggcccagtgagaaaagggaaagaa
ctaaacacacagcggagcttttttctcagaatgaagtgcaccctaacaagccgggggagg
acgatgaacatcaagtcagcaacgtggaaggtgcttcactgcacgggccatattcatgtc
tatgataccaacagtaaccaacctcagtgtgggtacaagaaaccacccatgacgtgcttg
gtgctgatttgtgaacccattcctcatccgtcaaatattgaaattcctttagatagcaag
acatttctcagtcgacacagcctcgatatgaaattttcttactgtgatgaaagaattact
gagttgatgggttatgagccggaagaacttttgggccgctcaatttatgaatattatcat
gctttggattctgatcatctgaccaaaactcaccatgatatgtttactaaaggacaagtc
accacaggacagtacaggatgcttgccaaaagaggtggatatgtctgggttgaaactcaa
gcaactgtcatatataatacgaagaactcccagccacagtgcattgtgtgtgtgaattat
gttgtaagtggtattattcagcacgacttgattttctcccttcaacaaacagaatctgtg
ctcaaaccagttgaatcttcagatatgaagatgactcagctgttcaccaaagttgaatca
gaggatacaagctgcctttttgataagcttaagaaggagcctgatgctctcactctgctg
gctccagctgccggcgacaccatcatctctctggattttggcagcgatgacacagaaact
gaagatcaacaacttgaagatgttccattatataatgatgtaatgtttccctcttctaat
gaaaaattaaatataaacctggcaatgtctcctttaccttcatcggaaactccaaagcca
cttcgaagtagtgctgatcctgcactgaatcaagaggttgcattaaaattagaatcaagt
ccagagtcactgggactttcttttaccatgccccagattcaagatcagccagcaagtcct
tctgatggaagcactagacaaagttcacctgagagacttcttcaggaaaacgtaaacact
cctaacttttcccagcctaacagtcccagtgaatattgctttgatgtggatagcgatatg
gtcaatgtattcaagttggaactggtggaaaaactgtttgctgaagacacagaggcaaag
aatccattttcaactcaggacactgatttagatttggagatgctggctccctatatccca
atggatgatgatttccagttacgttcctttgatcagttgtcaccattagagagcaattct
ccaagccctccaagtatgagcacagttactgggttccagcagacccagttacagaaacct
accatcactgccactgccaccacaactgccaccactgatgaatcaaaaacagagacgaag
gacaataaagaagatattaaaatactgattgcatctccatcttctacccaagtacctcaa
gaaacgaccactgctaaggcatcagcatacagtggcactcacagtcggacagcctcacca
gacagagcaggaaagagagtcatagaacagacagacaaagctcatccaaggagccttaac
ctgtctgccactttgaatcaaagaaatactgttcctgaggaagaattaaacccaaagaca
atagcttcgcagaatgctcagaggaagcgaaaaatggaacatgatggctccctttttcaa
gcagcaggaattggaacattattgcagcaaccaggtgactgtgcacctactatgtcactt
tcctggaaacgagtgaaaggattcatatctagtgaacagaatggaacggagcaaaagact
attattttaataccctccgatttagcatgcagactgctggggcagtcaatggatgagagt
ggattaccacagctgaccagttacgattgtgaagttaatgctcccatacaaggcagcaga
aacctactgcagggtgaagaattactcagagctttggatcaagttaactga
DBGET
integrated database retrieval system
