Mus musculus (house mouse): 16176 Help Entry 16176             CDS       T01002                                  Symbol Il1b, IL-1beta, Il-1b Name (RefSeq) interleukin 1 beta   KO K04519   interleukin 1 beta Organism mmu  Mus musculus (house mouse) Pathway mmu01523   Antifolate resistance mmu04010   MAPK signaling pathway mmu04060   Cytokine-cytokine receptor interaction mmu04064   NF-kappa B signaling pathway mmu04217   Necroptosis mmu04380   Osteoclast differentiation mmu04620   Toll-like receptor signaling pathway mmu04621   NOD-like receptor signaling pathway mmu04623   Cytosolic DNA-sensing pathway mmu04625   C-type lectin receptor signaling pathway mmu04640   Hematopoietic cell lineage mmu04657   IL-17 signaling pathway mmu04659   Th17 cell differentiation mmu04668   TNF signaling pathway mmu04750   Inflammatory mediator regulation of TRP channels mmu04932   Non-alcoholic fatty liver disease mmu04933   AGE-RAGE signaling pathway in diabetic complications mmu04936   Alcoholic liver disease mmu04940   Type I diabetes mellitus mmu05010   Alzheimer disease mmu05020   Prion disease mmu05022   Pathways of neurodegeneration - multiple diseases mmu05132   Salmonella infection mmu05133   Pertussis mmu05134   Legionellosis mmu05135   Yersinia infection mmu05140   Leishmaniasis mmu05142   Chagas disease mmu05143   African trypanosomiasis mmu05144   Malaria mmu05146   Amoebiasis mmu05152   Tuberculosis mmu05162   Measles mmu05163   Human cytomegalovirus infection mmu05164   Influenza A mmu05168   Herpes simplex virus 1 infection mmu05171   Coronavirus disease - COVID-19 mmu05321   Inflammatory bowel disease mmu05323   Rheumatoid arthritis mmu05332   Graft-versus-host disease mmu05417   Lipid and atherosclerosis mmu05418   Fluid shear stress and atherosclerosis Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     16176 (Il1b)    04064 NF-kappa B signaling pathway     16176 (Il1b)    04668 TNF signaling pathway     16176 (Il1b)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     16176 (Il1b)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     16176 (Il1b)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     16176 (Il1b)    04620 Toll-like receptor signaling pathway     16176 (Il1b)    04621 NOD-like receptor signaling pathway     16176 (Il1b)    04623 Cytosolic DNA-sensing pathway     16176 (Il1b)    04625 C-type lectin receptor signaling pathway     16176 (Il1b)    04659 Th17 cell differentiation     16176 (Il1b)    04657 IL-17 signaling pathway     16176 (Il1b)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     16176 (Il1b)   09158 Development and regeneration    04380 Osteoclast differentiation     16176 (Il1b)  09160 Human Diseases   09172 Infectious disease: viral    05171 Coronavirus disease - COVID-19     16176 (Il1b)    05164 Influenza A     16176 (Il1b)    05162 Measles     16176 (Il1b)    05168 Herpes simplex virus 1 infection     16176 (Il1b)    05163 Human cytomegalovirus infection     16176 (Il1b)   09171 Infectious disease: bacterial    05132 Salmonella infection     16176 (Il1b)    05135 Yersinia infection     16176 (Il1b)    05133 Pertussis     16176 (Il1b)    05134 Legionellosis     16176 (Il1b)    05152 Tuberculosis     16176 (Il1b)   09174 Infectious disease: parasitic    05146 Amoebiasis     16176 (Il1b)    05144 Malaria     16176 (Il1b)    05140 Leishmaniasis     16176 (Il1b)    05142 Chagas disease     16176 (Il1b)    05143 African trypanosomiasis     16176 (Il1b)   09163 Immune disease    05323 Rheumatoid arthritis     16176 (Il1b)    05321 Inflammatory bowel disease     16176 (Il1b)    05332 Graft-versus-host disease     16176 (Il1b)   09164 Neurodegenerative disease    05010 Alzheimer disease     16176 (Il1b)    05020 Prion disease     16176 (Il1b)    05022 Pathways of neurodegeneration - multiple diseases     16176 (Il1b)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     16176 (Il1b)    05418 Fluid shear stress and atherosclerosis     16176 (Il1b)   09167 Endocrine and metabolic disease    04940 Type I diabetes mellitus     16176 (Il1b)    04936 Alcoholic liver disease     16176 (Il1b)    04932 Non-alcoholic fatty liver disease     16176 (Il1b)    04933 AGE-RAGE signaling pathway in diabetic complications     16176 (Il1b)   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     16176 (Il1b)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:mmu04052]     16176 (Il1b)    00536 Glycosaminoglycan binding proteins [BR:mmu00536]     16176 (Il1b) Cytokines and neuropeptides [BR:mmu04052]  Cytokines   Interleukins    16176 (Il1b) Glycosaminoglycan binding proteins [BR:mmu00536]  Heparan sulfate / Heparin   Cytokines    16176 (Il1b) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IL1 IL1_propep ZinT Motif Other DBs NCBI-GeneID:  16176 NCBI-ProteinID:  NP_032387 MGI:  96543 Ensembl:  ENSMUSG00000027398 UniProt:  P10749 Structure PDBPDBj LinkDB All DBs Position 2:complement(129206490..129213059) Genome browser AA seq 269 aa AA seqDB search MATVPELNCEMPPFDSDENDLFFEVDGPQKMKGCFQTFDLGCPDESIQLQISQQHINKSF RQAVSLIVAVEKLWQLPVSFPWTFQDEDMSTFFSFIFEEEPILCDSWDDDDNLLVCDVPI RQLHYRLRDEQQKSLVLSDPYELKALHLNGQNINQQVIFSMSFVQGEPSNDKIPVALGLK GKNLYLSCVMKDGTPTLQLESVDPKQYPKKKMEKRFVFNKIEVKSKVEFESAEFPNWYIS TSQAEHKPVFLGNNSGQDIIDFTMESVSS NT seq 810 nt NT seq  +upstreamnt  +downstreamnt atggcaactgttcctgaactcaactgtgaaatgccaccttttgacagtgatgagaatgac ctgttctttgaagttgacggaccccaaaagatgaagggctgcttccaaacctttgacctg ggctgtcctgatgagagcatccagcttcaaatctcgcagcagcacatcaacaagagcttc aggcaggcagtatcactcattgtggctgtggagaagctgtggcagctacctgtgtctttc ccgtggaccttccaggatgaggacatgagcaccttcttttccttcatctttgaagaagag cccatcctctgtgactcatgggatgatgatgataacctgctggtgtgtgacgttcccatt agacaactgcactacaggctccgagatgaacaacaaaaaagcctcgtgctgtcggaccca tatgagctgaaagctctccacctcaatggacagaatatcaaccaacaagtgatattctcc atgagctttgtacaaggagaaccaagcaacgacaaaatacctgtggccttgggcctcaaa ggaaagaatctatacctgtcctgtgtaatgaaagacggcacacccaccctgcagctggag agtgtggatcccaagcaatacccaaagaagaagatggaaaaacggtttgtcttcaacaag atagaagtcaagagcaaagtggagtttgagtctgcagagttccccaactggtacatcagc acctcacaagcagagcacaagcctgtcttcctgggaaacaacagtggtcaggacataatt gacttcaccatggaatccgtgtcttcctaa

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