Mus musculus (house mouse): 16398
Help
Entry
16398 CDS
T01002
Symbol
Itga2, CD49B, DX5, GPIa
Name
(RefSeq) integrin alpha 2
KO
K06481
integrin alpha 2
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04145
Phagosome
mmu04151
PI3K-Akt signaling pathway
mmu04510
Focal adhesion
mmu04512
ECM-receptor interaction
mmu04611
Platelet activation
mmu04640
Hematopoietic cell lineage
mmu04810
Regulation of actin cytoskeleton
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05222
Small cell lung cancer
mmu05410
Hypertrophic cardiomyopathy
mmu05412
Arrhythmogenic right ventricular cardiomyopathy
mmu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04151 PI3K-Akt signaling pathway
16398 (Itga2)
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
16398 (Itga2)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
16398 (Itga2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
16398 (Itga2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
16398 (Itga2)
09150 Organismal Systems
09151 Immune system
04640 Hematopoietic cell lineage
16398 (Itga2)
04611 Platelet activation
16398 (Itga2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
16398 (Itga2)
05205 Proteoglycans in cancer
16398 (Itga2)
09162 Cancer: specific types
05222 Small cell lung cancer
16398 (Itga2)
09172 Infectious disease: viral
05165 Human papillomavirus infection
16398 (Itga2)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
16398 (Itga2)
05412 Arrhythmogenic right ventricular cardiomyopathy
16398 (Itga2)
05414 Dilated cardiomyopathy
16398 (Itga2)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
16398 (Itga2)
04515 Cell adhesion molecules [BR:
mmu04515
]
16398 (Itga2)
04090 CD molecules [BR:
mmu04090
]
16398 (Itga2)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of colorectal cancer cells
16398 (Itga2)
Exosomal proteins of bladder cancer cells
16398 (Itga2)
Cell adhesion molecules [BR:
mmu04515
]
Integrins
Integrin alpha subunits
16398 (Itga2)
CD molecules [BR:
mmu04090
]
Proteins
16398 (Itga2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Integrin_alpha2
VWA
FG-GAP
VWA_2
FG-GAP_2
FG-GAP_3
Integrin_alpha
DUF11
HisK_sensor
Motif
Other DBs
NCBI-GeneID:
16398
NCBI-ProteinID:
NP_032422
MGI:
96600
Ensembl:
ENSMUSG00000015533
UniProt:
Q62469
LinkDB
All DBs
Position
13:complement(114969617..115068636)
Genome browser
AA seq
1178 aa
AA seq
DB search
MGPGQAGGALLLRLLMLVQGILNCLAYNVGLPGAKIFSGPSSEQFGYSVQQLTNPQGNWL
LVGSPWSGFPENRMGDVYKCPVDLPTATCEKLNLQNSASISNVTEIKTNMSLGLTLTRNP
GTGGFLTCGPLWAHQCGNQYYATGICSDVSPDFQFLTSFSPAVQACPSLVDVVVVCDESN
SIYPWEAVKNFLVKFVTGLDIGPKKTQVALIQYANEPRIIFNLNDFETKEDMVQATSETR
QHGGDLTNTFRAIEFARDYAYSQTSGGRPGATKVMVVVTDGESHDGSKLKTVIQQCNDDE
ILRFGIAVLGYLNRNALDTKNLIKEIKAIASTPTERYFFNVADEAALLEKAGTLGEQIFS
IEGTVQGGDNFQMEMAQVGFSADYAPQNDILMLGAVGAFDWSGTLVQETSHKPVIFPKQA
FDQVLQDRNHSSFLGYSVAAISTEDGVHFVAGAPRANYTGQIVLYSVNKQGNVTVIQSHR
GDQIGSYFGSVLCSVDVDKDTITDVLLVGAPTYMNDLKKEEGKVYLFTITKGILNQHQFL
EGPEGTGNARFGSAIAALSDINMDGFNDVIVGSPVENENSGAVYIYNGHQGTIRTKYSQK
ILGSNGAFRRHLQFFGRSLDGYGDLNGDSITDVSIGALGQVIQLWSQSIADVAIEALFTP
DKITLLNKDAKITLKLCFRAEFRPAGQNNQVAILFNMTLDADGHSSRVTSRGVFRENSER
FLQKNMVVNEVQKCSEHHISIQKPSDVVNPLDLRVDISLENPGTSPALEAYSETVKVFSI
PFYKECGSDGICISDLILDVQQLPAIQTQSFIVSNQNKRLTFSVILKNRGESAYNTVVLA
EFSENLFFASFSMPVDGTEVTCEVGSSQKSVTCDVGYPALKSEQQVTFTINFDFNLQNLQ
NQAAINFQAFSESQETNKADNSVSLTIPLLYDAELHLTRSTNINFYEISSDENAPSVIKS
VEDIGPKFIFSLKVTAGSAPVSMALVTIHIPQYTKEKNPLLYLTGIQTDQAGDISCTAEI
NPLKLPHTAPSVSFKNENFRHTKELDCRTTSCSNITCWLKDLHMKAEYFINVTTRVWNRT
FAASTFQTVQLTAAAEIDTHNPQLFVIEENAVTIPLMIMKPTEKAEVPTGVIIGSIIAGI
LLLLAMTAGLWKLGFFKRQYKKMGQNPDEMDETTELNS
NT seq
3537 nt
NT seq
+upstream
nt +downstream
nt
atgggaccgggacaggcagggggcgcgctcctgctgcggctgctaatgctagttcaaggt
attttgaattgtctggcgtataatgttggcctcccaggagcgaaaatattttccgggcct
tcaagtgaacagtttgggtattcagtacagcagcttacgaacccacaaggcaactggcta
ctggttggttcaccgtggagtggcttccctgagaaccgaatgggagatgtgtacaagtgc
cctgtggacctacccactgccacctgtgaaaagctgaatctgcaaaattcagcaagcatc
tcaaatgttaccgagataaagaccaacatgagcctgggattgaccctcaccaggaatccg
gggaccggaggctttctaacctgtggtcctctctgggcacatcagtgtggaaatcagtat
tatgcaactgggatctgttctgatgttagtccagactttcagttcttgaccagcttttca
cctgcagttcaggcttgcccttccctcgtggatgttgtagttgtatgtgatgaatcaaac
agtatttatccttgggaagcagtaaagaactttttggtaaagtttgtgacaggcctggat
ataggacctaaaaagacacaggtggcgttaattcaatatgccaatgagccgagaattata
tttaacttgaacgatttcgaaaccaaagaggatatggtccaggccacatctgagacgcgc
caacatggtggggacctcacaaacaccttcagagctatcgaattcgcaagagactacgct
tattcacagacttctggcgggcgcccgggtgctacaaaagtcatggtagttgtgaccgat
ggcgagtcccatgatgggtcgaagctgaaaactgtgatccagcaatgcaatgatgacgag
atactgaggttcggcatagcagttcttgggtatttaaacagaaatgctcttgatactaaa
aatttaatcaaagaaataaaagcaattgctagtactccaaccgagagatactttttcaat
gtggccgacgaagcggctcttctggagaaggctggaactctaggggagcaaatattcagc
attgaaggcactgttcaaggaggagacaacttccagatggaaatggcacaagttggattc
agtgcagattacgctcctcaaaatgatattctgatgttaggtgcagtgggggcttttgac
tggagtggaactcttgtccaggagacatctcacaagcccgtgatctttcctaaacaagcc
tttgaccaggttctgcaggatagaaaccacagttcgtttttaggttactctgtggctgca
atttctactgaagacggtgtccattttgttgctggtgctcctcgagcaaattatactggc
cagatagtgttgtacagcgttaacaagcaaggcaatgtgaccgtgattcagtctcacaga
ggggaccagattggctcctattttggcagtgtgctgtgctcagttgatgtagataaagac
accattacagacgtgctcctggtaggtgctcctacatacatgaacgacctcaagaaagaa
gagggaaaagtctacctatttaccatcacaaagggcatcttgaatcagcaccagtttctt
gaagggccagaaggcactggaaatgctcggtttggttcagcaattgcagccctgtcagac
atcaacatggatggctttaatgatgtgattgtcggttcacctgtagagaatgagaactct
ggagctgtgtacatttacaatggtcaccagggtaccattcgcaccaagtactcccagaaa
atccttgggtccaatggagcctttaggagacatctccagttctttggaaggtccctggat
ggctatggtgatttaaatggggattccatcactgatgtatccattggtgctttggggcaa
gtgattcaactctggtcacaaagcattgctgacgtggccatagaagctttgttcactcca
gacaaaatcactttgctcaacaaggatgctaagataaccctaaagctctgcttcagagca
gagtttagacctgctgggcaaaacaatcaagtagccatcctgtttaacatgacgcttgat
gcggacggacattcatccagggtaacctccaggggggtgttcagagaaaacagtgagcga
ttcttgcagaagaatatggtggtaaacgaagtgcagaagtgttctgagcaccacattagc
atacagaagccctctgatgttgtcaaccctttggatctgcgtgtggacatcagtttggaa
aacccaggcactagccctgccctcgaagcctattctgaaactgtcaaagtcttcagtatc
cctttctataaggagtgtggcagcgatggaatttgcatctctgacctgatcctggatgtc
caacagctgccagccattcaaactcaatcctttattgtcagtaaccaaaacaagaggtta
acattttcagtcatcctgaaaaacagaggggaaagtgcatacaacactgtggtcctggcc
gagttttctgagaacttgttttttgcttctttctccatgccggtcgatggaacagaagta
acatgtgaggttggttcatcgcagaaatctgttacctgtgatgtgggataccctgcctta
aagagtgaacagcaggtgacttttaccattaacttcgactttaatcttcaaaacctccag
aaccaggcggccatcaatttccaagccttcagtgagagccaagaaacaaacaaagcagac
aattcggtcagtctcacgattcctctcctgtatgatgccgaacttcacttaacccgatcc
accaacatcaacttctatgagatctcttcggatgagaacgctccttctgtcatcaagagt
gtcgaagatattggtcctaaattcatcttctccctcaaggtaacagccggaagtgcccca
gtgagcatggcattggtgactatccacattcctcagtacaccaaggaaaagaacccactc
ctgtatctgactgggatacaaacagaccaggctggcgacatcagctgcacagcagaaata
aatccactcaagctaccacacaccgccccttctgtatctttcaagaatgaaaacttccgg
catacgaaagaattggactgcagaaccacttcctgcagtaacatcacctgctggctgaaa
gaccttcacatgaaagcagagtacttcatcaatgtgacaaccagagtttggaacaggacc
tttgctgcttcgactttccagactgtgcagctgacagcagcggcagagatcgatacacat
aaccctcagctcttcgtgattgaggaaaatgctgtcacgattcccctcatgataatgaaa
cccacggagaaagcagaagtaccgacaggggttatcataggcagcataattgcgggaatc
cttttgctgttggctatgactgcaggtttgtggaagctcggcttcttcaaaagacaatat
aagaaaatgggccaaaatccagatgagatggatgagaccacagaactcaacagctaa
Mus musculus (house mouse): 16412
Help
Entry
16412 CDS
T01002
Symbol
Itgb1, 4633401G24Rik, AA409975, AA960159, CD29, Fnrb, Gm9863, gpIIa
Name
(RefSeq) integrin beta 1 (fibronectin receptor beta)
KO
K05719
integrin beta 1
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04015
Rap1 signaling pathway
mmu04145
Phagosome
mmu04151
PI3K-Akt signaling pathway
mmu04360
Axon guidance
mmu04510
Focal adhesion
mmu04512
ECM-receptor interaction
mmu04514
Cell adhesion molecules
mmu04530
Tight junction
mmu04611
Platelet activation
mmu04670
Leukocyte transendothelial migration
mmu04810
Regulation of actin cytoskeleton
mmu05100
Bacterial invasion of epithelial cells
mmu05133
Pertussis
mmu05135
Yersinia infection
mmu05140
Leishmaniasis
mmu05145
Toxoplasmosis
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05222
Small cell lung cancer
mmu05410
Hypertrophic cardiomyopathy
mmu05412
Arrhythmogenic right ventricular cardiomyopathy
mmu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04015 Rap1 signaling pathway
16412 (Itgb1)
04151 PI3K-Akt signaling pathway
16412 (Itgb1)
09133 Signaling molecules and interaction
04512 ECM-receptor interaction
16412 (Itgb1)
04514 Cell adhesion molecules
16412 (Itgb1)
09140 Cellular Processes
09141 Transport and catabolism
04145 Phagosome
16412 (Itgb1)
09144 Cellular community - eukaryotes
04510 Focal adhesion
16412 (Itgb1)
04530 Tight junction
16412 (Itgb1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
16412 (Itgb1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
16412 (Itgb1)
04670 Leukocyte transendothelial migration
16412 (Itgb1)
09158 Development and regeneration
04360 Axon guidance
16412 (Itgb1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
16412 (Itgb1)
05205 Proteoglycans in cancer
16412 (Itgb1)
09162 Cancer: specific types
05222 Small cell lung cancer
16412 (Itgb1)
09172 Infectious disease: viral
05165 Human papillomavirus infection
16412 (Itgb1)
09171 Infectious disease: bacterial
05135 Yersinia infection
16412 (Itgb1)
05133 Pertussis
16412 (Itgb1)
05100 Bacterial invasion of epithelial cells
16412 (Itgb1)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
16412 (Itgb1)
05140 Leishmaniasis
16412 (Itgb1)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
16412 (Itgb1)
05412 Arrhythmogenic right ventricular cardiomyopathy
16412 (Itgb1)
05414 Dilated cardiomyopathy
16412 (Itgb1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
16412 (Itgb1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
16412 (Itgb1)
04515 Cell adhesion molecules [BR:
mmu04515
]
16412 (Itgb1)
04090 CD molecules [BR:
mmu04090
]
16412 (Itgb1)
Membrane trafficking [BR:
mmu04131
]
Endocytosis
Phagocytosis
Integrins (complement receptors)
16412 (Itgb1)
Exosome [BR:
mmu04147
]
Exosomal proteins
Proteins found in most exosomes
16412 (Itgb1)
Cell adhesion molecules [BR:
mmu04515
]
Integrins
Integrin beta subunits
16412 (Itgb1)
CD molecules [BR:
mmu04090
]
Proteins
16412 (Itgb1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Integrin_beta
Integrin_b_cyt
Integrin_B_tail
PSI_integrin
I-EGF_1
EGF_2
Motif
Other DBs
NCBI-GeneID:
16412
NCBI-ProteinID:
NP_034708
MGI:
96610
Ensembl:
ENSMUSG00000025809
Vega:
OTTMUSG00000034034
UniProt:
P09055
Structure
PDB
LinkDB
All DBs
Position
8:129412135..129460060
Genome browser
AA seq
798 aa
AA seq
DB search
MNLQLVSWIGLISLICSVFGQTDKNRCLKANAKSCGECIQAGPNCGWCTNTTFLQEGMPT
SARCDDLEALKKKGCQPSDIENPRGSQTIKKNKNVTNRSKGMAEKLRPEDITQIQPQQLL
LKLRSGEPQKFTLKFKRAEDYPIDLYYLMDLSYSMKDDLENVKSLGTDLMNEMRRITSDF
RIGFGSFVEKTVMPYISTTPAKLRNPCTSEQNCTSPFSYKNVLSLTDRGEFFNELVGQQR
ISGNLDSPEGGFDAIMQVAVCGSLIGWRNVTRLLVFSTDAGFHFAGDGKLGGIVLPNDGQ
CHLENNVYTMSHYYDYPSIAHLVQKLSENNIQTIFAVTEEFQPVYKELKNLIPKSAVGTL
SGNSSNVIQLIIDAYNSLSSEVILENSKLPDGVTINYKSYCKNGVNGTGENGRKCSNISI
GDEVQFEISITANKCPNKESETIKIKPLGFTEEVEVVLQFICKCNCQSHGIPASPKCHEG
NGTFECGACRCNEGRVGRHCECSTDEVNSEDMDAYCRKENSSEICSNNGECVCGQCVCRK
RDNTNEIYSGKFCECDNFNCDRSNGLICGGNGVCRCRVCECYPNYTGSACDCSLDTGPCL
ASNGQICNGRGICECGACKCTDPKFQGPTCETCQTCLGVCAEHKECVQCRAFNKGEKKDT
CAQECSHFNLTKVESREKLPQPVQVDPVTHCKEKDIDDCWFYFTYSVNGNNEAIVHVVET
PDCPTGPDIIPIVAGVVAGIVLIGLALLLIWKLLMIIHDRREFAKFEKEKMNAKWDTGEN
PIYKSAVTTVVNPKYEGK
NT seq
2397 nt
NT seq
+upstream
nt +downstream
nt
atgaatttgcaactggtttcctggattggattgatcagtttgatttgttctgtatttggc
caaacagataaaaatagatgtttaaaagcaaatgccaaatcttgcggagaatgtatacaa
gcagggccaaattgtgggtggtgtacaaatacgacatttttgcaagaaggaatgcctact
tctgcacgatgtgatgatttagaagctttgaaaaagaagggttgccagccaagtgacata
gagaatcccagaggctctcaaactataaagaaaaataaaaatgtcaccaatcgcagcaaa
gggatggcagagaagctccggccagaagacattactcagatccaaccacaacagctgctt
ctaaaattgagatcaggagaaccacagaagtttacattaaaattcaagagggctgaagat
taccctattgatctctactaccttatggatctctcctactctatgaaagatgatctggag
aatgtgaaaagtcttggaacggatttgatgaatgaaatgaggaggattacttcagacttc
cgcattggctttggctcatttgtggagaaaactgtgatgccgtatattagcacaacccca
gcaaagctaagaaatccttgtacaagtgaacaaaactgcaccagcccatttagctacaaa
aatgtgcttagtcttactgacagaggagagtttttcaatgaacttgttggtcagcaacgc
atatctggaaacttggattctccagaaggtggctttgatgcaatcatgcaggttgcggtt
tgtggatcgctgattggctggaggaatgtaacacgactgctggtgttttccacggatgct
gggtttcactttgctggagatgggaaacttggtggtattgttttacccaatgatggacaa
tgtcacctggaaaataatgtatatacaatgagccattactatgattatccttcaattgct
caccttgttcagaaactaagtgaaaataatattcagacgatttttgcagttactgaagag
ttccaacctgtttacaaggaattgaagaatttgattcctaagtcagcagtgggcacactg
tctggaaactctagtaatgtgatccagctaatcatcgatgcctacaactctctttcttca
gaagtcattctggaaaatagcaaattgccagacggagtaacaataaattacaaatcctat
tgcaagaatggggtgaatgggacaggagaaaatggacgaaagtgttccaacatttctatt
ggagatgaggttcaatttgaaattagcataactgctaataaatgtccaaataaggagtct
gaaaccattaaaattaaacctctgggcttcactgaagaagtagaggtcgttcttcagttc
atctgtaagtgcaattgtcaaagccatggcatcccagccagtcccaagtgccatgaggga
aatgggacatttgagtgtggagcctgcaggtgcaatgaggggcgtgttgggaggcactgt
gaatgtagcacagatgaagtgaacagtgaagacatggacgcttactgcaggaaagagaac
agttcggaaatctgcagtaacaatggagaatgtgtctgtggacagtgtgtgtgtaggaag
agagataatacaaatgaaatttactctggaaaattctgcgagtgtgataacttcaactgt
gataggtctaatggcttaatttgtggaggcaatggcgtgtgcaggtgtcgtgtttgtgaa
tgctatcccaattacactggcagtgcatgtgactgttctttggacactggtccatgtcta
gcgtcaaatggtcagatctgcaatggccggggtatttgtgaatgtggtgcttgtaagtgc
acagatcccaagtttcaagggccaacttgtgagacatgtcagacctgccttggcgtctgt
gcagagcataaagaatgtgttcagtgcagagccttcaataaaggagaaaagaaagacacg
tgtgcacaggagtgctcccacttcaatctcaccaaagtagaaagcagggagaagttgccc
cagccggtgcaggtcgatcctgtgacccattgcaaggagaaggacattgatgactgctgg
ttctatttcacctattcagtgaatggcaacaatgaagctatcgtgcatgttgtggagact
ccagactgtcctactggtcccgacatcatcccaattgtagcaggcgtggttgctggaatt
gttcttattggccttgccttgctgctgatttggaaacttttaatgataattcatgacaga
agggaatttgctaaatttgaaaaggagaaaatgaatgccaagtgggacacgggtgaaaat
cctatttacaagagtgccgtgacaactgtggtcaatccgaagtatgagggaaaatga
DBGET
integrated database retrieval system
