KEGG T01002: 16408

Mus musculus (house mouse): 16408

Entry

16408             CDS       T01002

Symbol

Itgal, (p180), Cd11a, LFA-1, LFA-1A, Ly-15, Ly-21

Name

(RefSeq) integrin alpha L

K05718

integrin alpha L

Organism

mmu Mus musculus (house mouse)

Pathway

mmu04015

Rap1 signaling pathway

mmu04514

Cell adhesion molecules

mmu04613

Neutrophil extracellular trap formation

mmu04650

Natural killer cell mediated cytotoxicity

mmu04670

Leukocyte transendothelial migration

mmu04810

Regulation of actin cytoskeleton

mmu05144

Malaria

mmu05150

Staphylococcus aureus infection

mmu05166

Human T-cell leukemia virus 1 infection

mmu05169

Epstein-Barr virus infection

mmu05323

Rheumatoid arthritis

mmu05416

Viral myocarditis

Brite

KEGG Orthology (KO) [BR:mmu00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04015 Rap1 signaling pathway
    16408 (Itgal)
  09133 Signaling molecules and interaction
   04514 Cell adhesion molecules
    16408 (Itgal)
09140 Cellular Processes
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    16408 (Itgal)
09150 Organismal Systems
  09151 Immune system
   04613 Neutrophil extracellular trap formation
    16408 (Itgal)
   04650 Natural killer cell mediated cytotoxicity
    16408 (Itgal)
   04670 Leukocyte transendothelial migration
    16408 (Itgal)
09160 Human Diseases
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    16408 (Itgal)
   05169 Epstein-Barr virus infection
    16408 (Itgal)
  09171 Infectious disease: bacterial
   05150 Staphylococcus aureus infection
    16408 (Itgal)
  09174 Infectious disease: parasitic
   05144 Malaria
    16408 (Itgal)
  09163 Immune disease
   05323 Rheumatoid arthritis
    16408 (Itgal)
  09166 Cardiovascular disease
   05416 Viral myocarditis
    16408 (Itgal)
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:mmu04147]
    16408 (Itgal)
   04515 Cell adhesion molecules [BR:mmu04515]
    16408 (Itgal)
   04090 CD molecules [BR:mmu04090]
    16408 (Itgal)
Exosome [BR:mmu04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   16408 (Itgal)
Cell adhesion molecules [BR:mmu04515]
Integrins
  Integrin alpha subunits
   16408 (Itgal)
CD molecules [BR:mmu04090]
Proteins
  16408 (Itgal)

SSDB

Motif

Pfam:

VWA FG-GAP Integrin_A_Ig_2 Integrin_A_Ig_1 VWA_2 FG-GAP_3 Integrin_alpha FG-GAP_2 ITGAX-like_Ig_3

Other DBs

NCBI-GeneID:

NCBI-ProteinID:

MGI:

Ensembl:

UniProt:

LinkDB

Position

7:126895404..126934309

AA seq 1162 aa
MSFRIAGPRLLLLGLQLFAKAWSYNLDTRPTQSFLAQAGRHFGYQVLQIEDGVVVGAPGE
GDNTGGLYHCRTSSEFCQPVSLHGSNHTSKYLGMTLATDAAKGSLLACDPGLSRTCDQNT
YLSGLCYLFPQSLEGPMLQNRPAYQECMKGKVDLVFLFDGSQSLDRKDFEKILEFMKDVM
RKLSNTSYQFAAVQFSTDCRTEFTFLDYVKQNKNPDVLLGSVQPMFLLTNTFRAINYVVA
HVFKEESGARPDATKVLVIITDGEASDKGNISAAHDITRYIIGIGKHFVSVQKQKTLHIF
ASEPVEEFVKILDTFEKLKDLFTDLQRRIYAIEGTNRQDLTSFNMELSSSGISADLSKGH
AVVGAVGAKDWAGGFLDLREDLQGATFVGQEPLTSDVRGGYLGYTVAWMTSRSSRPLLAA
GAPRYQHVGQVLLFQAPEAGGRWNQTQKIEGTQIGSYFGGELCSVDLDQDGEAELLLIGA
PLFFGEQRGGRVFTYQRRQSLFEMVSELQGDPGYPLGRFGAAITALTDINGDRLTDVAVG
APLEEQGAVYIFNGKPGGLSPQPSQRIQGAQVFPGIRWFGRSIHGVKDLGGDRLADVVVG
AEGRVVVLSSRPVVDVVTELSFSPEEIPVHEVECSYSAREEQKHGVKLKACFRIKPLTPQ
FQGRLLANLSYTLQLDGHRMRSRGLFPDGSHELSGNTSITPDKSCLDFHFHFPICIQDLI
SPINVSLNFSLLEEEGTPRDQKVGRAMQPILRPSIHTVTKEIPFEKNCGEDKKCEANLTL
SSPARSGPLRLMSSASLAVEWTLSNSGEDAYWVRLDLDFPRGLSFRKVEMLQPHSRMPVS
CEELTEGSSLLTKTLKCNVSSPIFKAGQEVSLQVMFNTLLNSSWEDFVELNGTVHCENEN
SSLQEDNSAATHIPVLYPVNILTKEQENSTLYISFTPKGPKTQQVQHVYQVRIQPSAYDH
NMPTLEALVGVPWPHSEDPITYTWSVQTDPLVTCHSEDLKRPSSEAEQPCLPGVQFRCPI
VFRREILIQVTGTVELSKEIKASSTLSLCSSLSVSFNSSKHFHLYGSKASEAQVLVKVDL
IHEKEMLHVYVLSGIGGLVLLFLIFLALYKVGFFKRNLKEKMEADGGVPNGSPPEDTDPL
AVPGEETKDMGCLEPLRESDKD

NT seq 3489 nt +upstreamnt +downstreamnt
atgagtttccggattgcgggccccagacttttgctactgggactccagctgtttgccaag
gcctggagctacaacctggacacacggcctacgcagagcttcttggcacaagctggaaga
cattttgggtaccaggtcttgcagattgaagatggggttgtcgtgggagccccaggtgag
ggggacaacacgggaggcctctatcactgccgaacaagcagcgagttctgccagccagtc
agcctacatggttctaaccatacctccaagtacttgggaatgacgctggcaacagatgcc
gccaagggaagccttttggcctgtgaccctggactgtctcggacatgcgatcagaacact
tacctcagtggcctctgctacctcttcccccagagtctggagggacctatgttacaaaat
cgtcccgcctatcaggaatgtatgaagggcaaagtcgacctggtgtttctgttcgatggc
tcacagagcttggatagaaaggactttgaaaaaatcctggaattcatgaaggatgtgatg
aggaagctcagcaatacttcctaccagtttgctgccgtccagttctccacagactgcaga
acagaatttactttcttggactacgttaagcagaacaagaaccccgatgttctgctaggc
agcgtgcagcccatgttcttgctgaccaatacctttcgtgccatcaactatgtggtggca
cacgtgttcaaagaagagtctggtgccaggccggatgctaccaaggtgcttgtcatcatt
acagacggggaggcaagtgataaaggcaacatcagtgcggcccacgacataacccgctac
atcatcgggattggcaagcattttgtgagcgtacaaaagcaaaagacgctccacatattt
gcctcagaacctgtagaggaatttgtgaagattctggacacctttgagaagctgaaggat
ctttttactgacctgcagaggaggatttatgctattgagggcacaaacagacaggacctg
acatcctttaacatggaactctcctccagcgggatcagcgcagacctcagcaagggccat
gcagttgtgggagctgttggggctaaggattgggccgggggctttctggacctgcgtgaa
gacctgcagggtgccacatttgttgggcaggaaccgctgacctcagatgtgagagggggc
tacctgggttacactgtggcctggatgacctcccggagctccagacccctgctggcagca
ggagccccacggtaccagcatgtgggacaagtactgcttttccaagccccagaggctgga
ggacgttggaaccaaacccagaagatagaagggactcagatcggatcttactttggtggg
gaactatgtagtgttgacctggaccaagatggcgaggcagagctgctgctgattggagca
cccctgttctttggggagcagagaggaggccgagtgttcacttaccagagaagacagtcg
ctgtttgaaatggtctcagagctacagggtgaccctggctacccgcttggtcggtttgga
gccgccataactgccctgacggacatcaatggggataggctgactgatgtggctgtggga
gcccctttggaggagcagggggctgtgtacatcttcaatgggaagcctggtgggctcagt
ccccagccaagccagcgtatacaaggagcccaggtgttcccaggaatccggtggtttggc
cgctccatccatggggtgaaggaccttggaggggacaggctggcagatgtggttgtagga
gctgagggtcgggtggttgtgctgagctccaggccggtggtggatgtggtcactgagctg
tcgttctccccagaggaaatcccagtgcacgaggtggagtgctcctactcagccagggag
gagcagaaacacggagtcaagctcaaggcatgcttccggatcaagcccctcacgccacag
tttcaaggtcgcctgcttgccaacctcagctacaccctgcagctggatggccatcggatg
aggagccgagggttgttcccagatggaagccacgagctcagtggaaacacctccatcacc
ccagataaatcctgcttggacttccacttccacttcccgatctgcattcaagacctcatc
tcccctatcaatgtctccctgaatttctctcttttggaggaagaaggaacaccaagggac
caaaaggtgggcagggccatgcagcctatcctgagaccttcaatccacacagtgactaag
gagatcccttttgagaagaactgtggtgaagataagaagtgtgaggcaaacctgaccctg
tcatcccctgccagatctggacccctgcgtctgatgtcctctgccagccttgctgtggag
tggacactgagcaactcaggggaagatgcctactgggtgcgattagacctggacttccct
cggggactctccttccggaaagtggagatgcttcagccacacagccgaatgcctgtgagc
tgcgaggagctcaccgaggggtcaagtctcctgactaagacactgaaatgcaatgtaagc
tctcccatcttcaaagcaggccaggaggtgagcctccaggtgatgtttaacacgctactc
aacagctcctgggaagacttcgttgagctgaatggcactgtgcactgtgagaatgagaac
tcaagcctccaggaggacaactcagccgccacccacattcctgtcctgtaccctgtcaac
atccttactaaggagcaggagaactccactctctatatcagtttcacccctaaaggtccc
aagacccaacaagtccagcatgtctaccaggtgaggattcagccatctgcctatgaccac
aacatgcccacactagaggccttggttggggtgccctggcctcacagtgaggaccccatc
acatacacatggagtgtacagacggatccccttgtcacttgccacagcgaggacctgaag
aggccgtccagcgaagctgagcagccttgtctgcctggagtccagttccgctgtccaatt
gtcttcaggcgggagatcctcatccaagtgacggggaccgtggaactctccaaggaaatc
aaggcctcctccacactcagcctctgcagctcactctccgtctccttcaacagcagcaag
catttccatttgtatggcagcaaagcctccgaggcccaggtcctcgtgaaggttgacctg
atccacgagaaggagatgcttcacgtgtacgtactcagcggcattgggggcctcgtgctt
ctgttcctgattttcctggcgctctacaaggttggcttcttcaaacggaacctgaaggag
aagatggaggctgatggaggtgttccaaatggaagccctccagaagacactgaccctctg
gcagtacctggggaagagaccaaagatatgggctgtctagagcccctccgggagagtgac
aaggactaa

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