Mus musculus (house mouse): 16414 Help Entry 16414             CDS       T01002                                  Symbol Itgb2, 2E6, Cd18, LAD, LCAMB, Lfa1, MF17 Name (RefSeq) integrin beta 2   KO K06464   integrin beta 2 Organism mmu  Mus musculus (house mouse) Pathway mmu04015   Rap1 signaling pathway mmu04145   Phagosome mmu04390   Hippo signaling pathway mmu04514   Cell adhesion molecules mmu04610   Complement and coagulation cascades mmu04613   Neutrophil extracellular trap formation mmu04650   Natural killer cell mediated cytotoxicity mmu04670   Leukocyte transendothelial migration mmu04810   Regulation of actin cytoskeleton mmu05133   Pertussis mmu05134   Legionellosis mmu05140   Leishmaniasis mmu05144   Malaria mmu05146   Amoebiasis mmu05150   Staphylococcus aureus infection mmu05152   Tuberculosis mmu05166   Human T-cell leukemia virus 1 infection mmu05323   Rheumatoid arthritis mmu05416   Viral myocarditis Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     16414 (Itgb2)    04390 Hippo signaling pathway     16414 (Itgb2)   09133 Signaling molecules and interaction    04514 Cell adhesion molecules     16414 (Itgb2)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     16414 (Itgb2)   09142 Cell motility    04810 Regulation of actin cytoskeleton     16414 (Itgb2)  09150 Organismal Systems   09151 Immune system    04610 Complement and coagulation cascades     16414 (Itgb2)    04613 Neutrophil extracellular trap formation     16414 (Itgb2)    04650 Natural killer cell mediated cytotoxicity     16414 (Itgb2)    04670 Leukocyte transendothelial migration     16414 (Itgb2)  09160 Human Diseases   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     16414 (Itgb2)   09171 Infectious disease: bacterial    05133 Pertussis     16414 (Itgb2)    05134 Legionellosis     16414 (Itgb2)    05150 Staphylococcus aureus infection     16414 (Itgb2)    05152 Tuberculosis     16414 (Itgb2)   09174 Infectious disease: parasitic    05146 Amoebiasis     16414 (Itgb2)    05144 Malaria     16414 (Itgb2)    05140 Leishmaniasis     16414 (Itgb2)   09163 Immune disease    05323 Rheumatoid arthritis     16414 (Itgb2)   09166 Cardiovascular disease    05416 Viral myocarditis     16414 (Itgb2)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mmu04131]     16414 (Itgb2)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:mmu04147]     16414 (Itgb2)    04515 Cell adhesion molecules [BR:mmu04515]     16414 (Itgb2)    04090 CD molecules [BR:mmu04090]     16414 (Itgb2) Membrane trafficking [BR:mmu04131]  Endocytosis   Phagocytosis    Integrins (complement receptors)     16414 (Itgb2) Exosome [BR:mmu04147]  Exosomal proteins   Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)    16414 (Itgb2) Cell adhesion molecules [BR:mmu04515]  Integrins   Integrin beta subunits    16414 (Itgb2) CD molecules [BR:mmu04090]  Proteins   16414 (Itgb2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Integrin_beta EGF_integrin Integrin_b_cyt Integrin_B_tail PSI_integrin EGF_2 vWA_SIBA-E EGF_Teneurin Motif Other DBs NCBI-GeneID:  16414 NCBI-ProteinID:  NP_032430 MGI:  96611 Ensembl:  ENSMUSG00000000290 UniProt:  P11835 Q542I8 Structure PDBPDBj LinkDB All DBs Position 10:77366164..77401542 Genome browser AA seq 770 aa AA seqDB search MLGPHSLLLALAGLFFLGSAVSQECTKYKVSSCRDCIQSGPGCSWCQKLNFTGPGEPDSL RCDTRAQLLLKGCPADDIMDPRSIANPEFDQRGQRKQLSPQKVTLYLRPGQAAAFNVTFR RAKGYPIDLYYLMDLSYSMLDDLNNVKKLGGDLLQALNEITESGRIGFGSFVDKTVLPFV NTHPEKLRNPCPNKEKACQPPFAFRHVLKLTDNSNQFQTEVGKQLISGNLDAPEGGLDAI MQVAACPEEIGWRNVTRLLVFATDDGFHFAGDGKLGAILTPNDGRCHLEDNMYKRSNEFD YPSVGQLAHKLSESNIQPIFAVTKKMVKTYEKLTEIIPKSAVGELSDDSSNVVQLIKNAY YKLSSRVFLDHSTLPDTLKVTYDSFCSNGASSIGKSRGDCDGVQINNPVTFQVKVMASEC IQEQSFVIRALGFTDTVTVQVRPQCECQCRDQSREQSLCGGKGVMECGICRCESGYIGKN CECQTQGRSSQELERNCRKDNSSIVCSGLGDCICGQCVCHTSDVPNKEIFGQYCECDNVN CERYNSQVCGGSDRGSCNCGKCSCKPGYEGSACQCQRSTTGCLNARLVECSGRGHCQCNR CICDEGYQPPMCEDCPSCGSHCRDNHTSCAECLKFDKGPFEKNCSVQCAGMTLQTIPLKK KPCKERDSEGCWITYTLQQKDGRNIYNIHVEDSLECVKGPNVAAIVGGTVVGVVLIGVLL LVIWKALTHLTDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES NT seq 2313 nt NT seq  +upstreamnt  +downstreamnt atgctgggcccacactcactgctgcttgccctagctggactgttcttcctgggatctgct gtgtcccaggaatgcaccaagtacaaagtcagcagttgccgggactgtatccagtcgggg cctggctgttcctggtgccagaagctgaacttcactggaccaggagaacctgactccttg cgctgtgacacacgggcacagctgctgctgaagggttgtccagccgatgatatcatggac cccaggagcatcgctaatcctgagttcgaccaacgggggcaacggaaacagctatctcca caaaaagtgacactttacttgcgaccaggacaggctgccgcattcaatgtgactttccgg cgggccaagggataccccattgatctgtactacctcatggatctctcctactccatgctt gatgacctcaacaacgtcaagaagctgggcggggacttgctgcaggccctcaacgagatc accgagtctggccgcatcggctttgggtcgtttgtggacaagacggtgctgccttttgtt aacacccatcctgagaagctgaggaacccatgtcccaacaaggagaaggcctgccagccc ccatttgcctttcggcacgtgctcaagttaaccgacaactccaaccagtttcagacagag gtcggcaagcaactgatttccggaaacctggacgcccctgagggtgggctggatgccata atgcaagttgctgcatgtccggaggaaattggctggcgcaatgtcacgaggctgctggtg tttgccacagacgatggcttccactttgctggtgatggcaaactgggtgccatcctgacc cccaatgatggccgctgccacctggaggataacatgtacaagaggagcaatgagttcgac tacccatccgtgggtcagctggcacacaaactttccgagagcaacatccagcccatcttt gcggtgacaaagaagatggtgaaaacgtatgagaaactcacggagatcatccccaagtca gcagtgggggaactgtctgacgactccagcaacgtggtgcagctcatcaagaatgcctac tataaactctcctctagagtcttcctggaccacagcaccctcccggacaccctgaaagtc acctatgactccttctgcagtaatggagcatcgagtataggcaaatcccgtggggactgt gatggcgtacagatcaacaacccggtcaccttccaggtaaaggtcatggcttccgagtgt atccaggagcagtcctttgtcatccgggcactgggtttcacggatacagtgaccgtgcag gtccgtccccagtgtgagtgtcagtgccgggaccagagtcgggagcagagtctctgtgga ggcaagggagtcatggagtgtggtatctgcaggtgtgagtctggctacattgggaaaaac tgtgagtgccagactcagggtcggagcagccaggagctggagagaaactgtcggaaggac aatagttccatcgtgtgctcagggcttggggactgcatctgtgggcagtgtgtatgccat accagtgacgtccccaacaaagagatctttgggcaatactgcgagtgtgacaatgtcaac tgtgagagatataacagccaagtctgcggtggctcagatcggggttcctgcaactgtggc aaatgtagttgcaagcccggttacgagggctcggcctgccagtgtcagaggtccaccacg ggctgtctgaatgcacggctggtagagtgcagtggccgtggccactgccaatgcaacagg tgcatatgtgacgaaggctaccagccaccgatgtgtgaggattgtcccagctgtggctcg cactgcagggacaaccacacctcttgtgccgagtgcctgaagtttgataagggccctttt gagaagaactgtagtgttcagtgtgctggtatgacgctgcagactatccctttgaagaaa aagccctgcaaggagagggactcggaaggctgttggataacttacactttgcagcagaag gacggaaggaacatttacaacatccatgtggaggacagtctagagtgtgtgaagggcccc aatgtggctgccatcgtagggggcaccgtggtaggtgtcgtactgattggtgtcctcctc ctggtcatctggaaggccctgacccacctgactgacctcagggagtacaggcgctttgag aaggagaaactcaagtcccaatggaacaatgacaaccccctcttcaagagtgctacgaca acggtcatgaaccccaagtttgctgaaagctag

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