Mus musculus (house mouse): 16542
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Entry
16542 CDS
T01002
Symbol
Kdr, 6130401C07, Flk-1, Flk1, Krd-1, Ly73, VEGFR-2, VEGFR2, orv, sVEGFR-2
Name
(RefSeq) kinase insert domain protein receptor
KO
K05098
kinase insert domain protein receptor [EC:
2.7.10.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01521
EGFR tyrosine kinase inhibitor resistance
mmu04010
MAPK signaling pathway
mmu04014
Ras signaling pathway
mmu04015
Rap1 signaling pathway
mmu04020
Calcium signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu04370
VEGF signaling pathway
mmu04510
Focal adhesion
mmu05205
Proteoglycans in cancer
mmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
16542 (Kdr)
04014 Ras signaling pathway
16542 (Kdr)
04015 Rap1 signaling pathway
16542 (Kdr)
04370 VEGF signaling pathway
16542 (Kdr)
04020 Calcium signaling pathway
16542 (Kdr)
04151 PI3K-Akt signaling pathway
16542 (Kdr)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
16542 (Kdr)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
16542 (Kdr)
09166 Cardiovascular disease
05418 Fluid shear stress and atherosclerosis
16542 (Kdr)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
16542 (Kdr)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
16542 (Kdr)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
mmu04090
]
16542 (Kdr)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
16542 (Kdr)
Protein kinases [BR:
mmu01001
]
Receptor tyrosine kinases (RTK)
VEGFR family [OT]
16542 (Kdr)
CD molecules [BR:
mmu04090
]
Proteins
16542 (Kdr)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
VEGFR1-3_N_Ig-like
Ig_3
I-set
Pkinase
Ig_2
ig
VEGFR-1-like_Ig-like
V-set
VEGFR-2_TMD
Ig_VEGFR-1-like_5th
C2-set_2
Ig_4
Ig_5
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
16542
NCBI-ProteinID:
NP_034742
MGI:
96683
Ensembl:
ENSMUSG00000062960
UniProt:
P35918
LinkDB
All DBs
Position
5:complement(76093487..76139880)
Genome browser
AA seq
1345 aa
AA seq
DB search
MESKALLAVALWFCVETRAASVGLPGDFLHPPKLSTQKDILTILANTTLQITCRGQRDLD
WLWPNAQRDSEERVLVTECGGGDSIFCKTLTIPRVVGNDTGAYKCSYRDVDIASTVYVYV
RDYRSPFIASVSDQHGIVYITENKNKTVVIPCRGSISNLNVSLCARYPEKRFVPDGNRIS
WDSEIGFTLPSYMISYAGMVFCEAKINDETYQSIMYIVVVVGYRIYDVILSPPHEIELSA
GEKLVLNCTARTELNVGLDFTWHSPPSKSHHKKIVNRDVKPFPGTVAKMFLSTLTIESVT
KSDQGEYTCVASSGRMIKRNRTFVRVHTKPFIAFGSGMKSLVEATVGSQVRIPVKYLSYP
APDIKWYRNGRPIESNYTMIVGDELTIMEVTERDAGNYTVILTNPISMEKQSHMVSLVVN
VPPQIGEKALISPMDSYQYGTMQTLTCTVYANPPLHHIQWYWQLEEACSYRPGQTSPYAC
KEWRHVEDFQGGNKIEVTKNQYALIEGKNKTVSTLVIQAANVSALYKCEAINKAGRGERV
ISFHVIRGPEITVQPAAQPTEQESVSLLCTADRNTFENLTWYKLGSQATSVHMGESLTPV
CKNLDALWKLNGTMFSNSTNDILIVAFQNASLQDQGDYVCSAQDKKTKKRHCLVKQLIIL
ERMAPMITGNLENQTTTIGETIEVTCPASGNPTPHITWFKDNETLVEDSGIVLRDGNRNL
TIRRVRKEDGGLYTCQACNVLGCARAETLFIIEGAQEKTNLEVIILVGTAVIAMFFWLLL
VIVLRTVKRANEGELKTGYLSIVMDPDELPLDERCERLPYDASKWEFPRDRLKLGKPLGR
GAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSEHRALMSELKILIHIGHHLNVVNLL
GACTKPGGPLMVIVEFCKFGNLSTYLRGKRNEFVPYKSKGARFRQGKDYVGELSVDLKRR
LDSITSSQSSASSGFVEEKSLSDVEEEEASEELYKDFLTLEHLICYSFQVAKGMEFLASR
KCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMAPETIFDRVY
TIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQTMLDC
WHEDPNQRPSFSELVEHLGNLLQANAQQDGKDYIVLPMSETLSMEEDSGLSLPTSPVSCM
EEEEVCDPKFHYDNTAGISHYLQNSKRKSRPVSVKTFEDIPLEEPEVKVIPDDSQTDSGM
VLASEELKTLEDRNKLSPSFGGMMPSKSRESVASEGSNQTSGYQSGYHSDDTDTTVYSSD
EAGLLKMVDAAVHADSGTTLRSPPV
NT seq
4038 nt
NT seq
+upstream
nt +downstream
nt
atggagagcaaggcgctgctagctgtcgctctgtggttctgcgtggagacccgagccgcc
tctgtgggtttgcctggcgattttctccatccccccaagctcagcacacagaaagacata
ctgacaattttggcaaatacaacccttcagattacttgcaggggacagcgggacctggac
tggctttggcccaatgctcagcgtgattctgaggaaagggtattggtgactgaatgcggc
ggtggtgacagtatcttctgcaaaacactcaccattcccagggtggttggaaatgatact
ggagcctacaagtgctcgtaccgggacgtcgacatagcctccactgtttatgtctatgtt
cgagattacagatcaccattcatcgcctctgtcagtgaccagcatggcatcgtgtacatc
accgagaacaagaacaaaactgtggtgatcccctgccgagggtcgatttcaaacctcaat
gtgtctctttgcgctaggtatccagaaaagagatttgttccggatggaaacagaatttcc
tgggacagcgagataggctttactctccccagttacatgatcagctatgccggcatggtc
ttctgtgaggcaaagatcaatgatgaaacctatcagtctatcatgtacatagttgtggtt
gtaggatataggatttatgatgtgattctgagccccccgcatgaaattgagctatctgcc
ggagaaaaacttgtcttaaattgtacagcgagaacagagctcaatgtggggcttgatttc
acctggcactctccaccttcaaagtctcatcataagaagattgtaaaccgggatgtgaaa
ccctttcctgggactgtggcgaagatgtttttgagcaccttgacaatagaaagtgtgacc
aagagtgaccaaggggaatacacctgtgtagcgtccagtggacggatgatcaagagaaat
agaacatttgtccgagttcacacaaagccttttattgctttcggtagtgggatgaaatct
ttggtggaagccacagtgggcagtcaagtccgaatccctgtgaagtatctcagttaccca
gctcctgatatcaaatggtacagaaatggaaggcccattgagtccaactacacaatgatt
gttggcgatgaactcaccatcatggaagtgactgaaagagatgcaggaaactacacggtc
atcctcaccaaccccatttcaatggagaaacagagccacatggtctctctggttgtgaat
gtcccaccccagatcggtgagaaagccttgatctcgcctatggattcctaccagtatggg
accatgcagacattgacatgcacagtctacgccaaccctcccctgcaccacatccagtgg
tactggcagctagaagaagcctgctcctacagacccggccaaacaagcccgtatgcttgt
aaagaatggagacacgtggaggatttccaggggggaaacaagatcgaagtcaccaaaaac
caatatgccctgattgaaggaaaaaacaaaactgtaagtacgctggtcatccaagctgcc
aacgtgtcagcgttgtacaaatgtgaagccatcaacaaagcgggacgaggagagagggtc
atctccttccatgtgatcaggggtcctgaaattactgtgcaacctgctgcccagccaact
gagcaggagagtgtgtccctgttgtgcactgcagacagaaatacgtttgagaacctcacg
tggtacaagcttggctcacaggcaacatcggtccacatgggcgaatcactcacaccagtt
tgcaagaacttggatgctctttggaaactgaatggcaccatgttttctaacagcacaaat
gacatcttgattgtggcatttcagaatgcctctctgcaggaccaaggcgactatgtttgc
tctgctcaagataagaagaccaagaaaagacattgcctggtcaaacagctcatcatccta
gagcgcatggcacccatgatcaccggaaatctggagaatcagacaacaaccattggcgag
accattgaagtgacttgcccagcatctggaaatcctaccccacacattacatggttcaaa
gacaacgagaccctggtagaagattcaggcattgtactgagagatgggaaccggaacctg
actatccgcagggtgaggaaggaggatggaggcctctacacctgccaggcctgcaatgtc
cttggctgtgcaagagcggagacgctcttcataatagaaggtgcccaggaaaagaccaac
ttggaagtcattatcctcgtcggcactgcagtgattgccatgttcttctggctccttctt
gtcattgtcctacggaccgttaagcgggccaatgaaggggaactgaagacaggctacttg
tctattgtcatggatccagatgaattgcccttggatgagcgctgtgaacgcttgccttat
gatgccagcaagtgggaattccccagggaccggctgaaactaggaaaacctcttggccgc
ggtgccttcggccaagtgattgaggcagacgcttttggaattgacaagacagcgacttgc
aaaacagtagccgtcaagatgttgaaagaaggagcaacacacagcgagcatcgagccctc
atgtctgaactcaagatcctcatccacattggtcaccatctcaatgtggtgaacctccta
ggcgcctgcaccaagccgggagggcctctcatggtgattgtggaattctgcaagtttgga
aacctatcaacttacttacggggcaagagaaatgaatttgttccctataagagcaaaggg
gcacgcttccgccagggcaaggactacgttggggagctctccgtggatctgaaaagacgc
ttggacagcatcaccagcagccagagctctgccagctcaggctttgttgaggagaaatcg
ctcagtgatgtagaggaagaagaagcttctgaagaactgtacaaggacttcctgaccttg
gagcatctcatctgttacagcttccaagtggctaagggcatggagttcttggcatcaagg
aagtgtatccacagggacctggcagcacgaaacattctcctatcggagaagaatgtggtt
aagatctgtgacttcggcttggcccgggacatttataaagacccggattatgtcagaaaa
ggagatgcccgactccctttgaagtggatggccccggaaaccatttttgacagagtatac
acaattcagagcgatgtgtggtctttcggtgtgttgctctgggaaatattttccttaggt
gcctccccataccctggggtcaagattgatgaagaattttgtaggagattgaaagaagga
actagaatgcgggctcctgactacactaccccagaaatgtaccagaccatgctggactgc
tggcatgaggaccccaaccagagaccctcgttttcagagttggtggagcatttgggaaac
ctcctgcaagcaaatgcgcagcaggatggcaaagactatattgttcttccaatgtcagag
acactgagcatggaagaggattctggactctccctgcctacctcacctgtttcctgtatg
gaggaagaggaagtgtgcgaccccaaattccattatgacaacacagcaggaatcagtcat
tatctccagaacagtaagcgaaagagccggccagtgagtgtaaaaacatttgaagatatc
ccattggaggaaccagaagtaaaagtgatcccagatgacagccagacagacagtgggatg
gtccttgcatcagaagagctgaaaactctggaagacaggaacaaattatctccatctttt
ggtggaatgatgcccagtaaaagcagggagtctgtggcctcggaaggctccaaccagacc
agtggctaccagtctgggtatcactcagatgacacagacaccaccgtgtactccagcgac
gaggcaggacttttaaagatggtggatgctgcagttcacgctgactcagggaccacactg
cgctcacctcctgtttaa
DBGET
integrated database retrieval system
