KEGG   Mus musculus (house mouse): 16842
Entry
16842             CDS       T01002                                 
Symbol
Lef1, 3000002B05, Lef-1
Name
(RefSeq) lymphoid enhancer binding factor 1
  KO
K04492  lymphoid enhancer-binding factor 1
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu04310  Wnt signaling pathway
mmu04390  Hippo signaling pathway
mmu04520  Adherens junction
mmu04916  Melanogenesis
mmu04934  Cushing syndrome
mmu04936  Alcoholic liver disease
mmu05132  Salmonella infection
mmu05167  Kaposi sarcoma-associated herpesvirus infection
mmu05200  Pathways in cancer
mmu05210  Colorectal cancer
mmu05213  Endometrial cancer
mmu05215  Prostate cancer
mmu05216  Thyroid cancer
mmu05217  Basal cell carcinoma
mmu05221  Acute myeloid leukemia
mmu05224  Breast cancer
mmu05225  Hepatocellular carcinoma
mmu05226  Gastric cancer
mmu05412  Arrhythmogenic right ventricular cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    16842 (Lef1)
   04390 Hippo signaling pathway
    16842 (Lef1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04520 Adherens junction
    16842 (Lef1)
 09150 Organismal Systems
  09152 Endocrine system
   04916 Melanogenesis
    16842 (Lef1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    16842 (Lef1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    16842 (Lef1)
   05225 Hepatocellular carcinoma
    16842 (Lef1)
   05226 Gastric cancer
    16842 (Lef1)
   05216 Thyroid cancer
    16842 (Lef1)
   05221 Acute myeloid leukemia
    16842 (Lef1)
   05217 Basal cell carcinoma
    16842 (Lef1)
   05215 Prostate cancer
    16842 (Lef1)
   05213 Endometrial cancer
    16842 (Lef1)
   05224 Breast cancer
    16842 (Lef1)
  09172 Infectious disease: viral
   05167 Kaposi sarcoma-associated herpesvirus infection
    16842 (Lef1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    16842 (Lef1)
  09166 Cardiovascular disease
   05412 Arrhythmogenic right ventricular cardiomyopathy
    16842 (Lef1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    16842 (Lef1)
   04934 Cushing syndrome
    16842 (Lef1)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03000 Transcription factors [BR:mmu03000]
    16842 (Lef1)
Transcription factors [BR:mmu03000]
 Eukaryotic type
  beta-Scaffold factors with minor groove contacts
   HMG TCF-1
    16842 (Lef1)
SSDB
Motif
Pfam: CTNNB1_binding HMG_box HMG_box_2 HMG_WDHD1
Other DBs
NCBI-GeneID: 16842
NCBI-ProteinID: NP_034833
MGI: 96770
Ensembl: ENSMUSG00000027985
UniProt: P27782 Q8BGZ9 Q3TYB0
Structure
LinkDB
Position
3:130903972..131018006
AA seq 397 aa
MPQLSGGGGGGDPELCATDEMIPFKDEGDPQKEKIFAEISHPEEEGDLADIKSSLVNESE
IIPASNGHEVVRQAPSSQEPYHDKAREHPDEGKHPDGGLYNKGPSYSSYSGYIMMPNMNS
DPYMSNGSLSPPIPRTSNKVPVVQPSHAVHPLTPLITYSDEHFSPGSHPSHIPSDVNSKQ
GMSRHPPAPEIPTFYPLSPGGVGQITPPIGWQGQPVYPITGGFRQPYPSSLSGDTSMSRF
SHHMIPGPPGPHTTGIPHPAIVTPQVKQEHPHTDSDLMHVKPQHEQRKEQEPKRPHIKKP
LNAFMLYMKEMRANVVAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQL
YPGWSARDNYGKKKKRKREKLQESTSGTGPRMTAAYI
NT seq 1194 nt   +upstreamnt  +downstreamnt
atgccccaactttccggaggaggcggcgggggggacccggaactctgcgccaccgatgag
atgatccccttcaaggacgaaggcgatccccagaaggagaagatcttcgccgagatcagt
catcccgaagaggagggcgacttagccgacatcaagtcatctttggttaacgagtccgaa
atcatcccagccagcaacgggcatgaggtggtcagacaagccccgtcctctcaggagccc
taccacgacaaggccagagaacaccctgatgaaggaaagcatccagacggaggcctgtac
aacaagggaccctcctactccagttactctggctacataatgatgcccaatatgaacagc
gacccgtacatgtcaaatgggtccctttctccacccatcccgaggacatcaaataaagtg
cccgtggtgcagccctctcacgcggtccacccgctcacccccctcatcacctacagcgac
gagcacttttctccgggatcccacccgtcacacatcccgtcagatgtcaactccaagcaa
ggcatgtccagacaccctccagctcctgaaatccccaccttctaccccctgtctccgggc
ggcgttggacagatcaccccacccattggctggcaaggtcagcctgtttatcccatcacg
ggtggattcaggcaaccctacccatcctcactgtcaggcgacacttccatgtccaggttt
tcccatcatatgattcctggtccccctggcccccacacaactggcatccctcatccagct
attgtaacacctcaggtcaaacaggagcacccccacacggacagtgacctaatgcacgtg
aagcctcaacacgaacagagaaaggagcaggagcccaaaagacctcatattaagaagcct
ctgaatgctttcatgttatatatgaaagaaatgagagcgaatgtcgtagctgagtgcacg
ctaaaggagagtgcagctatcaaccagatcctgggcagaagatggcacgccctctcccgg
gaagagcaggccaaatactatgaactagcacggaaagagagacagctacacatgcagctt
tatccaggctggtcagcgcgagacaattatggcaagaagaagaagaggaagagagagaag
ctacaggagtcgacttcaggtacaggtcccagaatgacagctgcctacatctga

DBGET integrated database retrieval system