Mus musculus (house mouse): 170768
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Entry
170768 CDS
T01002
Symbol
Pfkfb3, E330010H22Rik, iPFK-2, uPFK-2
Name
(RefSeq) 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
KO
K01103
6-phosphofructo-2-kinase / fructose-2,6-biphosphatase 3 [EC:
2.7.1.105
3.1.3.46
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00051
Fructose and mannose metabolism
mmu01100
Metabolic pathways
mmu04066
HIF-1 signaling pathway
mmu04152
AMPK signaling pathway
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00051 Fructose and mannose metabolism
170768 (Pfkfb3)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
170768 (Pfkfb3)
04152 AMPK signaling pathway
170768 (Pfkfb3)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.105 6-phosphofructo-2-kinase
170768 (Pfkfb3)
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.46 fructose-2,6-bisphosphate 2-phosphatase
170768 (Pfkfb3)
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Gene cluster
GFIT
Motif
Pfam:
6PF2K
His_Phos_1
AAA_33
KTI12
AAA_18
Zeta_toxin
DIL
SRP54
APS_kinase
Motif
Other DBs
NCBI-GeneID:
170768
NCBI-ProteinID:
NP_001171223
MGI:
2181202
Ensembl:
ENSMUSG00000026773
UniProt:
A7UAK4
Q7TS91
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Position
2:complement(11476241..11558882)
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AA seq
462 aa
AA seq
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MPLELTQSRVQKIWVPVDHRPSLPRSCGPKLTNSPTVIVMVGLPARGKTYISKKLTRYLN
WIGVPTKVFNVGEYRREAVKQYSSYNFFRPDNEEAMRVRKQCALAALRDVKSYLTKEGGQ
IAVFDATNTTRERRHMILNFAKENDFKAFFIESVCDDPTVVASNIMEVKISSPDYKDCNS
AEAMDDFMKRINCYEASYQPLDPDKCDRDLSLIKVIDVGRRFLVNRVQDHIQSRIVYYLM
NIHVQPRTIYLCRHGENEYNLQGKIGGDSGLSSRGKKFANALSKFVEEQNLKDLRVWTSQ
LKSTIQTAEALRLPYEQWKALNEIDAGVCEELTYEEIRDTYPEEYALREQDKYYYRYPTG
ESYQDLVQRLEPVIMELERQENVLVICHQAVLRCLLAYFLDKSAEEMPYLKCPLHTVLKL
TPVAYGCRVESIYLNVESVSTHRERSENMKSSRSGADSSQKH
NT seq
1389 nt
NT seq
+upstream
nt +downstream
nt
atgccgttggaactgacccagagccgggtacagaagatctgggtgcccgtcgatcaccga
ccctcgttgcccagatcctgtgggccgaagctgaccaactccccaaccgtgattgtgatg
gtggggctcccagcccggggtaagacttacatctccaagaagctgactcgctacctcaac
tggataggtgttccaacgaaagtgttcaatgtgggagagtatcggcgtgaggctgtgaag
cagtacagctcttacaacttcttccgccctgacaatgaggaagccatgagagtccgaaaa
cagtgtgccttagctgccctgagagatgtcaaaagctacctgacaaaggaaggtggacag
attgcagtttttgatgccaccaatacaactagagaaagaaggcacatgatccttaatttt
gccaaagaaaatgacttcaaggcatttttcatcgagtcggtctgtgacgaccctactgtt
gtggcctccaacatcatggaagttaaaatctccagcccggattacaaagactgcaactca
gcagaagccatggacgacttcatgaagagaatcaattgctatgaagccagctaccagcct
cttgaccctgataaatgtgacagggacttgtcactcatcaaagtgattgatgttggccgg
aggttcttggtgaacagagtgcaggaccacatccagagccgaattgtatactacctgatg
aacatccacgtgcagccccgtaccatctacctgtgtcggcatggcgagaatgagtacaac
ttgcagggcaagattgggggcgactcaggcttgtccagcagaggcaagaagttcgccaat
gccctgagcaagttcgtagaagaacagaatctgaaggacctccgtgtgtggaccagccag
ctgaaaagtaccattcagaccgcggaggccctgaggctcccctacgagcagtggaaggca
ctcaacgagatcgatgctggtgtgtgtgaggaactaacctatgaggagatcagagatacc
taccctgaggagtacgcactgcgtgaacaggacaagtactactatcgctatcccacggga
gagtcctaccaggatcttgtccaacgcctggagcctgtgatcatggaattagagcgccaa
gagaatgtattggtcatctgtcaccaggctgttctacgctgcctactagcctacttcctc
gacaagagtgcagaggagatgccatacctgaaatgtccgctccacactgtcctgaaactg
acacctgtggcatatgggtgccgggtggagtccatttacttgaatgtagaatcggtgagc
acacaccgggagaggtcagagaacatgaagagctcccggagcggtgccgactcttcccag
aagcactaa
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