Mus musculus (house mouse): 17096
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Entry
17096 CDS
T01002
Symbol
Lyn, AA407514, Hck-2, p53Lyn, p56Lyn
Name
(RefSeq) LYN proto-oncogene, Src family tyrosine kinase
KO
K05854
tyrosine-protein kinase Lyn [EC:
2.7.10.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04062
Chemokine signaling pathway
mmu04064
NF-kappa B signaling pathway
mmu04611
Platelet activation
mmu04662
B cell receptor signaling pathway
mmu04664
Fc epsilon RI signaling pathway
mmu04666
Fc gamma R-mediated phagocytosis
mmu04730
Long-term depression
mmu05167
Kaposi sarcoma-associated herpesvirus infection
mmu05169
Epstein-Barr virus infection
mmu05203
Viral carcinogenesis
mmu05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
17096 (Lyn)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
17096 (Lyn)
04662 B cell receptor signaling pathway
17096 (Lyn)
04664 Fc epsilon RI signaling pathway
17096 (Lyn)
04666 Fc gamma R-mediated phagocytosis
17096 (Lyn)
04062 Chemokine signaling pathway
17096 (Lyn)
09156 Nervous system
04730 Long-term depression
17096 (Lyn)
09160 Human Diseases
09161 Cancer: overview
05203 Viral carcinogenesis
17096 (Lyn)
09172 Infectious disease: viral
05167 Kaposi sarcoma-associated herpesvirus infection
17096 (Lyn)
05169 Epstein-Barr virus infection
17096 (Lyn)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
17096 (Lyn)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
17096 (Lyn)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
17096 (Lyn)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
17096 (Lyn)
Protein kinases [BR:
mmu01001
]
Non-receptor tyrosine kinases
SRC family
17096 (Lyn)
Membrane trafficking [BR:
mmu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
17096 (Lyn)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH3_3
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
17096
NCBI-ProteinID:
NP_001104566
MGI:
96892
Ensembl:
ENSMUSG00000042228
UniProt:
P25911
Q3TCS3
Q8CEI0
Structure
PDB
LinkDB
All DBs
Position
4:3676865..3791612
Genome browser
AA seq
512 aa
AA seq
DB search
MGCIKSKRKDNLNDDEVDSKTQPVRNTDRTIYVRDPTSNKQQRPVPEFHLLPGQRFQTKD
PEEQGDIVVALYPYDGIHPDDLSFKKGEKMKVLEEHGEWWKAKSLSSKREGFIPSNYVAK
VNTLETEEWFFKDITRKDAERQLLAPGNSAGAFLIRESETLKGSFSLSVRDYDPMHGDVI
KHYKIRSLDNGGYYISPRITFPCISDMIKHYQKQSDGLCRRLEKACISPKPQKPWDKDAW
EIPRESIKLVKKLGAGQFGEVWMGYYNNSTKVAVKTLKPGTMSVQAFLEEANLMKTLQHD
KLVRLYAVVTKEEPIYIITEFMAKGSLLDFLKSDEGGKVLLPKLIDFSAQIAEGMAYIER
KNYIHRDLRAANVLVSESLMCKIADFGLARVIEDNEYTAREGAKFPIKWTAPEAINFGCF
TIKSDVWSFGILLYEIVTYGKIPYPGRTNADVMSALSQGYRMPRMENCPDELYDIMKMCW
KEKAEERPTFDYLQSVLDDFYTATEGQYQQQP
NT seq
1539 nt
NT seq
+upstream
nt +downstream
nt
atgggatgtattaaatcaaaaaggaaagacaatctcaatgacgatgaagtagattcgaag
actcaaccagtacgtaatactgaccgaactatttatgtgagagatccaacgtccaataaa
cagcaaaggccagttcctgaatttcatcttttaccaggacagagatttcaaacaaaagat
ccagaggaacaaggtgacattgtggtggccttatacccttatgatggcatccacccagat
gacttgtccttcaagaaaggagaaaagatgaaagttctagaagagcatggggaatggtgg
aaagctaagtccctttcatcaaagagagaaggcttcatccccagcaactacgtggccaag
gtcaacaccttagaaactgaagagtggttcttcaaggacataacaaggaaagatgcagag
cgacagcttctggcaccagggaacagtgcaggagctttccttatcagagaaagcgaaact
ttaaagggaagcttctctctttctgtcagagattatgaccctatgcatggtgatgtcatt
aagcactacaaaattagaagtctggacaatggtggctattacatctctcctcgcatcact
tttccctgcatcagtgacatgattaagcattaccaaaagcagtctgatggtctatgcaga
agactggagaaggcatgcatcagtcccaaacctcagaagccatgggataaagatgcctgg
gagatcccccgggagtccattaagttggtgaaaaagcttggcgcagggcagtttggggaa
gtctggatgggttactataacaacagcacaaaggtggctgtgaagaccctcaagcccggc
accatgtctgtgcaggcattcctggaagaggccaacctcatgaagaccttgcaacatgac
aagctagtgcggctgtacgctgtggtcaccaaggaggagcccatctacatcatcaccgag
ttcatggctaagggtagtttgctggatttcctcaagagtgatgaaggtggcaaggtgctg
ctgcccaagctcattgacttctcggcccagattgcagaaggcatggcgtacatcgagcgg
aagaactacatccaccgtgatctgcgagctgctaacgtcctggtctctgagtcactcatg
tgcaagattgcagactttggcctcgcgagagtcatcgaagataacgagtacacagcaagg
gaaggtgcgaagttccctatcaagtggacagctccagaggccatcaacttcggctgcttc
actatcaaatctgacgtgtggtccttcggaattctcctgtatgagattgtcacctatggg
aagattccctacccagggagaaccaacgcagatgtgatgagcgcactgtcacagggatat
cgaatgccacgcatggagaactgcccagatgagctctatgacatcatgaaaatgtgttgg
aaagaaaaggcagaggagaggccaacttttgactacttacagagtgtcctggatgacttc
tatacagccacagaagggcagtatcagcagcaaccgtag
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