Mus musculus (house mouse): 17350
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Entry
17350 CDS
T01002
Symbol
Mlh1, 1110035C23Rik, AI317206, AI325952, AI561766
Name
(RefSeq) mutL homolog 1
KO
K08734
DNA mismatch repair protein MLH1
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01524
Platinum drug resistance
mmu03430
Mismatch repair
mmu03460
Fanconi anemia pathway
mmu05200
Pathways in cancer
mmu05210
Colorectal cancer
mmu05213
Endometrial cancer
mmu05226
Gastric cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09124 Replication and repair
03430 Mismatch repair
17350 (Mlh1)
03460 Fanconi anemia pathway
17350 (Mlh1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
17350 (Mlh1)
09162 Cancer: specific types
05210 Colorectal cancer
17350 (Mlh1)
05226 Gastric cancer
17350 (Mlh1)
05213 Endometrial cancer
17350 (Mlh1)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
17350 (Mlh1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03400 DNA repair and recombination proteins [BR:
mmu03400
]
17350 (Mlh1)
DNA repair and recombination proteins [BR:
mmu03400
]
Eukaryotic type
SSBR (single strand breaks repair)
MMR (mismatch excision repair)
MutL homologs
17350 (Mlh1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mlh1_C
DNA_mis_repair
HATPase_c_3
HATPase_c
Motif
Other DBs
NCBI-GeneID:
17350
NCBI-ProteinID:
NP_081086
MGI:
101938
Ensembl:
ENSMUSG00000032498
UniProt:
Q9JK91
LinkDB
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Position
9:complement(111057296..111100854)
Genome browser
AA seq
760 aa
AA seq
DB search
MAFVAGVIRRLDETVVNRIAAGEVIQRPANAIKEMIENCLDAKSTNIQVVVKEGGLKLIQ
IQDNGTGIRKEDLDIVCERFTTSKLQTFEDLASISTYGFRGEALASISHVAHVTITTKTA
DGKCAYRASYSDGKLQAPPKPCAGNQGTLITVEDLFYNIITRRKALKNPSEEYGKILEVV
GRYSIHNSGISFSVKKQGETVSDVRTLPNATTVDNIRSIFGNAVSRELIEVGCEDKTLAF
KMNGYISNANYSVKKCIFLLFINHRLVESAALRKAIETVYAAYLPKNTHPFLYLSLEISP
QNVDVNVHPTKHEVHFLHEESILQRVQQHIESKLLGSNSSRMYFTQTLLPGLAGPSGEAA
RPTTGVASSSTSGSGDKVYAYQMVRTDSREQKLDAFLQPVSSLGPSQPQDPAPVRGARTE
GSPERATREDEEMLALPAPAEAAAESENLERESLMETSDAAQKAAPTSSPGSSRKRHRED
SDVEMVENASGKEMTAACYPRRRIINLTSVLSLQEEISERCHETLREMLRNHSFVGCVNP
QWALAQHQTKLYLLNTTKLSEELFYQILIYDFANFGVLRLSEPAPLFDLAMLALDSPESG
WTEDDGPKEGLAEYIVEFLKKKAEMLADYFSVEIDEEGNLIGLPLLIDSYVPPLEGLPIF
ILRLATEVNWDEEKECFESLSKECAMFYSIRKQYILEESTLSGQQSDMPGSTSKPWKWTV
EHIIYKAFRSHLLPPKHFTEDGNVLQLANLPDLYKVFERC
NT seq
2283 nt
NT seq
+upstream
nt +downstream
nt
atggcgtttgtagcaggagttattcggcgtctggacgagacggtagtgaaccgcatagcg
gcgggggaagtcattcagcggccggccaatgctatcaaagagatgatagaaaactgttta
gatgcaaaatctacaaatattcaagtggttgttaaggaaggtggcctgaagctaattcag
atccaagacaatggcactggaatcaggaaggaagatctggatattgtgtgtgagaggttc
actacgagtaaactgcagacttttgaggatttagccagtatttctacctatggctttcgt
ggtgaggcattggcaagcataagccatgtggcccatgtcactattacaaccaaaacagct
gatgggaaatgtgcgtacagagcaagttactcagatggaaagctgcaagcccctcctaaa
ccctgtgcaggcaaccagggcaccctgatcacggtggaagaccttttttacaacataatc
acaaggaggaaagctttaaaaaatccaagtgaagagtacggaaaaattttggaagttgtt
ggcaggtattcaatacacaattcaggcattagtttctcagttaaaaaacaaggtgagaca
gtatctgatgtcagaacactgcccaatgccacaaccgtggacaacattcgctccatcttt
ggaaatgcggttagtcgagaactgatagaagttgggtgtgaggataaaaccctagctttc
aaaatgaatggctatatatcgaatgcaaactattcagtgaagaagtgcattttcctactc
ttcatcaaccaccgtctggtagaatcagctgccttgagaaaagccattgaaactgtatat
gcagcatacttgcccaaaaacacacacccattcctgtacctcagtttggaaatcagccct
cagaacgtggacgtcaatgtacaccccaccaagcacgaagttcactttctgcacgaggag
agcattctgcagcgtgtgcagcagcacattgagagcaagctgctgggctccaattcctcc
aggatgtatttcacccagaccttgcttccaggacttgctgggccttctggggaggcagct
agacccacgacaggggtggcttcctcatccactagtggaagtggcgacaaggtctacgct
taccagatggtccgtacggactcccgggagcagaagcttgacgcctttctgcagcctgta
agcagccttgggcccagccagccccaggaccctgcccctgtccgaggggccaggacggag
ggatctcctgaaagggccacgcgggaggacgaggagatgcttgctctcccagcccccgct
gaagcagctgctgagagtgagaacttggagagggaatcactaatggagacttcagacgca
gcccagaaggcggcacccacttccagtccaggaagctccagaaagagacatcgggaggac
tctgatgtggaaatggtggaaaatgcttccgggaaggaaatgacagctgcttgctacccc
aggaggaggatcattaacctcaccagcgtcttgagtctccaggaagagattagtgagcgg
tgccatgagactctccgggagatgctccgtaaccattcctttgtgggctgtgtgaatcct
cagtgggccttggcacagcaccagaccaagctctacctcctcaacactaccaagctcagt
gaagagctgttctaccagatactcatttatgattttgccaactttggtgttctgaggtta
tcggaaccagcgccactcttcgacctggccatgctggccttagacagtcctgaaagtggc
tggacagaggacgacggcccgaaggaagggcttgcagagtacattgttgagtttctgaag
aagaaagcggagatgcttgcagactatttctctgtggagatcgatgaggaagggaacctg
attggattacctcttctgattgacagctatgtgccacctttggagggactgcctatcttc
attcttcgactggccactgaggtgaattgggatgaagaaaaggagtgttttgaaagtctc
agtaaagaatgtgctatgttttactccattcggaagcagtatatactggaggagtcgacc
ctctcaggccagcagagtgacatgcctggctccacgtcaaagccctggaagtggactgtg
gagcacattatctataaagccttccgctcacacctcctacctccgaagcatttcacagaa
gatggcaatgtcctgcagcttgccaacctgccagatctatacaaagtctttgagcggtgt
taa
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