Mus musculus (house mouse): 17535
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Entry
17535 CDS
T01002
Symbol
Mre11a, Mre11, Mre11b
Name
(RefSeq) MRE11A homolog A, double strand break repair nuclease
KO
K10865
double-strand break repair protein MRE11
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu03440
Homologous recombination
mmu03450
Non-homologous end-joining
mmu04218
Cellular senescence
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
17535 (Mre11a)
03450 Non-homologous end-joining
17535 (Mre11a)
09140 Cellular Processes
09143 Cell growth and death
04218 Cellular senescence
17535 (Mre11a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mmu03032
]
17535 (Mre11a)
03400 DNA repair and recombination proteins [BR:
mmu03400
]
17535 (Mre11a)
DNA replication proteins [BR:
mmu03032
]
Eukaryotic type
DNA Replication Termination Factors
MRN complex
17535 (Mre11a)
DNA repair and recombination proteins [BR:
mmu03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
MRN(MRX) complex
17535 (Mre11a)
BRCA1-C complex
17535 (Mre11a)
NHEJ (non-homologous end-joining)
MRX complex
17535 (Mre11a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Mre11_DNA_bind
Metallophos
Motif
Other DBs
NCBI-GeneID:
17535
NCBI-ProteinID:
NP_061206
MGI:
1100512
Ensembl:
ENSMUSG00000031928
UniProt:
Q61216
Q3URU4
Q3TU24
LinkDB
All DBs
Position
9:14695971..14748421
Genome browser
AA seq
706 aa
AA seq
DB search
MSPTDPLDDEDTFKILVATDIHLGFMEKDAVRGNDTFVTFDEILRLALENEVDFILLGGD
LFHENKPSRKTLHSCLELLRKYCMGDRPVQFEVISDQSVNFGFSKFPWVNYQDGNLNISI
PVFSIHGNHDDPTGADALCALDVLSCAGFVNHFGRSMSVEKVDISPVLLQKGSTKLALYG
LGSIPDERLYRMFVNKKVTMLRPKEDENSWFNLFVIHQNRSKHGNTNFIPEQFLDDFIDL
VIWGHEHECKIGPIKNEQQLFYVSQPGSSVVTSLSPGEAVKKHVGLLRIKGRKMNMQKLP
LRTVRRFFIEDVVLANHPNLFNPDNPKVTQAIQSFCLEKIEEMLDSAERERLGNPQQPGK
PLIRLRVDYSGGFEPFNVLRFSQKFVDRVANPKDVIHFFRHREQKGKTGEEINFGMLITK
PASEGATLRVEDLVKQYFQTAEKNVQLSLLTERGMGEAVQEFVDKEEKDAIEELVKYQLE
KTQRFLKERHIDALEDKIDEEVRRFRESRQRNTNEEDDEVREAMSRARALRSQSETSTSA
FSAEDLSFDTSEQTANDSDDSLSAVPSRGRGRGRGRRGARGQSSAPRGGSQRGRDTGLEI
TTRGRSSKATSSTSRNMSIIDAFRSTRQQPSRNVAPKNYSETIEVDDSDEDDIFPTNSRA
DQRWSGTTSSKRMSQSQTAKGVDFESDEDDDDDPFMSSSCPRRNRR
NT seq
2121 nt
NT seq
+upstream
nt +downstream
nt
atgagccccacagatccacttgacgatgaagacacatttaaaatcctggttgccactgat
attcatcttggatttatggagaaagatgcagttagaggaaatgatacatttgtgacattt
gatgaaatcttaagacttgccctggaaaatgaagtggattttattttgttaggtggtgat
cttttccatgaaaacaagccctcgaggaaaaccctgcacagctgcttggagctgcttagg
aagtactgtatgggtgaccgccctgtgcagtttgaggtcatcagtgatcagtcagtcaac
tttggttttagtaagtttccatgggtgaactaccaggatggcaatctcaacatttccatt
ccagtatttagtatccacggcaaccatgatgatcccacgggggcagatgccctctgtgcc
ctggatgttttaagctgtgctgggtttgtgaatcactttggacggtcaatgtcggtggag
aaggttgacattagtccggttctgctgcagaaaggaagcacaaaactcgctctgtacggc
ttaggctccattccagatgaaaggctctatcggatgtttgtgaataaaaaagtaacaatg
ttgagaccaaaggaagatgagaactcatggtttaacttatttgtgattcatcagaacagg
agtaagcatggaaacaccaacttcattccagagcagtttttggatgacttcatcgacctc
gttatctggggccatgaacatgagtgtaaaattggcccaatcaaaaatgagcagcagctc
ttctatgtgtctcagcccggaagctcagtggtgacgtccctttcccctggagaagctgtg
aagaaacatgtaggcttgctgcgcattaaagggagaaagatgaacatgcagaagctgcct
ctccgcaccgtgcggcggttcttcatagaagacgtggttctggctaaccacccaaacctg
ttcaaccctgacaatcctaaggtgacccaggccatccagagcttctgtctggagaagatt
gaagaaatgcttgacagtgctgagcgggaacgactggggaatcctcagcagccggggaag
cctcttatccgactacgggtggactatagtggaggctttgaacctttcaacgttcttcgt
tttagccagaagtttgtggatcgagtcgctaacccaaaagatgtcatccactttttcagg
cacagggaacaaaagggaaaaacaggagaagagatcaactttgggatgctcatcacaaaa
cctgcttcagaaggagcaacgcttagagtagaagacctcgtaaagcagtatttccaaact
gcagagaagaatgttcagctctcgctgctgacagaaagagggatgggcgaagcagttcaa
gagtttgtggacaaggaagagaaagatgccatcgaggaattagtgaagtaccagctggag
aaaacacagcggtttcttaaggagcgccatattgatgctctggaagacaagattgatgag
gaggtccgacgtttccgagaaagcagacagagaaataccaacgaagaagatgatgaagtt
cgagaggccatgagcagagcccgggccctcagatcacagtcagagacctccacctcagcc
tttagtgctgaggacctgagctttgatacatcggagcagacagcaaatgactctgatgac
agcctgtcagcagtgccgagcagaggccgaggccgaggccgagggcgaagaggagccaga
gggcagagctcggcacctagaggaggctctcagagaggccgagacactgggctggagatc
actactcgaggcaggagctcaaaggccacctcatcaacatctagaaacatgtccattata
gacgctttcagatctacccgacaacagccttctagaaatgtagcccctaagaattactca
gagaccattgaggtggatgactctgacgaagatgacatttttcctaccaattccagggct
gatcaaaggtggtcgggcacaacatctagcaaacggatgtcccagagccagacagccaaa
ggggtagactttgaatcagatgaggatgatgacgatgaccctttcatgagcagtagttgc
ccaagaagaaaccgaagataa
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