Mus musculus (house mouse): 18222
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Entry
18222 CDS
T01002
Symbol
Numb, Nb
Name
(RefSeq) NUMB endocytic adaptor protein
KO
K06057
numb
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
18222 (Numb)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
18222 (Numb)
Membrane trafficking [BR:
mmu04131
]
Endocytosis
Clathrin-mediated endocytosis
LDLR adaptor proteins
18222 (Numb)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PID
NumbF
PTB
PID_2
Motif
Other DBs
NCBI-GeneID:
18222
NCBI-ProteinID:
NP_001129547
MGI:
107423
Ensembl:
ENSMUSG00000021224
UniProt:
Q9QZS3
Structure
PDB
PDBj
LinkDB
All DBs
Position
12:complement(83840808..83968708)
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AA seq
653 aa
AA seq
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MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED
AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD
RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA
TFDASRTTFTREGSFRVTTATEQAEREEIMKQLQDAKKAETDKTVVGPSVAPGNTAPSPS
SPTSPTPDGTASSEMNNPHAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINE
LPSTMQRKTDFPIKNTVPEVEGEAESISSLCSQITSAFSTPSEDPFSSAPMTKPVTLVAP
QSPVLQANGTDSASHVLTAKPANTALAHVAMPVRETNPWAHVPDAANKEIAAIHPGTEWG
QSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQVSAAPLQPVLQPPPPAAIAPP
APPFQGHAFLTSQPVPVGVVPPLQPAFVPTQSYPVANGMPYPASNVPVVGITPSQMVANV
FGTAGHPQTTHPHQSPSLAKQQTFPQYETSSATTSPFFKPPAQHLNGSAAFNGVDNGGLA
SGNRHAEVPPGTCPVDPFEAQWAALESKSKQRTNPSPTNPFSSDLQKTFEIEL
NT seq
1962 nt
NT seq
+upstream
nt +downstream
nt
atgaacaaactacggcaaagcttcaggagaaagaaagacgtttatgtcccagaggccagc
cgtccacatcagtggcagacagatgaagaaggagtccgcactggaaagtgtagcttccca
gttaagtacctcggccacgtagaagttgatgagtcaagaggaatgcacatctgtgaagat
gccgtaaagagattgaaagctgaaaggaagttcttcaaaggcttctttggaaaaacggga
aagaaagcagtgaaggccgttctgtgggtgtcagcggatgggctcagagttgtggacgag
aaaactaaggacctcatagttgaccagacaatagaaaaagtttccttctgtgccccagat
aggaactttgacagagccttttcttacatatgtcgtgatggcaccactcggcgatggatc
tgtcattgtttcatggctgtcaaagacacgggggaaagactgagccacgccgtgggctgt
gcttttgcagcctgtttagagcgtaaacagaagcgggagaaggagtgtggcgtcactgct
acttttgatgccagtagaaccactttcacaagagaaggatcattccgtgtcacaactgcc
actgagcaagccgaaagagaggagatcatgaaacagttgcaagatgccaagaaagctgag
acagacaagacagttgttggtccatcagtggctcctggcaacactgctccatccccatcc
tctcccacctctcccactccggatggcactgcatcttcagagatgaacaatccccatgct
atcccacgccggcatgcaccaattgaacagcttgctcgtcaaggctctttccggggattt
cctgctcttagccagaagatgtcaccctttaaacgccagctgtccctacgcatcaatgag
ttgccttccactatgcagaggaagaccgatttcccaataaaaaacacagtgcccgaggtg
gaaggagaggccgagagcatcagctccttgtgttcccagatcaccagtgccttcagcacg
ccctctgaggaccccttctcctccgccccaatgaccaaaccagtgacattggtggcacca
cagtctcctgtgttacaagctaatggcactgactcagcctcccatgtgcttactgctaag
ccagccaatactgctctagcacacgtagcaatgcctgtccgtgaaaccaacccctgggcc
catgtccctgatgctgctaacaaggaaattgcagccatacatccggggactgagtggggt
cagtcttctggtgctgcctctccaggtctcttccaggctggtcacagacgcactccctct
gaagctgaccgctggttagaagaagtgtcaaagagtgtgcgggcccagcagcctcaggtc
tcagctgcccctctgcagccagttctccagccgcctccgcccgccgccattgcccctcca
gcacctcctttccaaggacatgccttcctcacgtcccagcctgtgcccgtgggtgtggtc
ccacccctacaaccagcctttgtccctacccagtcctaccctgtggccaacgggatgccc
tacccagcctctaatgtgcctgtagtgggcatcaccccatcccagatggtagccaatgtg
tttggcactgcaggccaccctcagacaactcatccacatcagtcgccaagcctggccaag
cagcagacattccctcaatatgagacaagtagtgctaccaccagtcccttctttaagcct
cctgctcagcacctcaatggttctgcagctttcaatggtgtagacaatggtgggctagcc
tcaggaaacaggcatgcagaagtccctccaggcacctgcccagtggatcctttcgaagct
cagtgggccgcactagaaagcaagtccaagcagcgtacaaatccttctcctaccaaccct
ttctccagtgacttacagaaaacatttgaaatagaactttag
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