Mus musculus (house mouse): 18576
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Entry
18576 CDS
T01002
Symbol
Pde3b, 9830102A01Rik
Name
(RefSeq) phosphodiesterase 3B, cGMP-inhibited
KO
K13296
cGMP-inhibited 3',5'-cyclic phosphodiesterase B [EC:
3.1.4.17
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00230
Purine metabolism
mmu01100
Metabolic pathways
mmu04022
cGMP-PKG signaling pathway
mmu04024
cAMP signaling pathway
mmu04371
Apelin signaling pathway
mmu04910
Insulin signaling pathway
mmu04914
Progesterone-mediated oocyte maturation
mmu04922
Glucagon signaling pathway
mmu04923
Regulation of lipolysis in adipocytes
mmu04924
Renin secretion
mmu05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
18576 (Pde3b)
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
18576 (Pde3b)
04024 cAMP signaling pathway
18576 (Pde3b)
04022 cGMP-PKG signaling pathway
18576 (Pde3b)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
18576 (Pde3b)
04922 Glucagon signaling pathway
18576 (Pde3b)
04923 Regulation of lipolysis in adipocytes
18576 (Pde3b)
04914 Progesterone-mediated oocyte maturation
18576 (Pde3b)
04924 Renin secretion
18576 (Pde3b)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
18576 (Pde3b)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.17 3',5'-cyclic-nucleotide phosphodiesterase
18576 (Pde3b)
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GFIT
Motif
Pfam:
PDEase_I
Motif
Other DBs
NCBI-GeneID:
18576
NCBI-ProteinID:
NP_035185
MGI:
1333863
Ensembl:
ENSMUSG00000030671
UniProt:
Q61409
E9QLQ3
Q3UQ25
LinkDB
All DBs
Position
7:114014388..114137173
Genome browser
AA seq
1099 aa
AA seq
DB search
MRKDERERDAPAMRSPPPPPASAASPPESLRNGYVKSCVSPLRQDPPRSFFFHLCRFCNV
EPPAASLRAGARLSLGVLAAFVLAALLGARPERWAAAAAGLRTLLSACSLSLSPLFSIAC
AFFFLTCFLTRAQRGPGRGAGSWWLLALPACCYLGDFAAWQWWSWLRGEPAAAGRLCLVL
SCVGLLTLAPRVRLRHGVLVLLFAGLVWWVSFSGLGALPPALRPLLSCLVGGAGCLLALG
LDHFFHVRGASPPPRSASTAEEKVPVIRPRRRSSCVSLGESAAGYYGSGKMFRRPSLPCI
SREQMILWDWDLKQWCKPHYQNSGGGNGVDLSVLNEARNMVSDLLIDPSLPPQVISSLRS
ISSLMGAFSGSCRPKINSFTPFPGFYPCSEVEDPVEKGDRKLHKGLSGRTSFPTPQLRRS
SGASSLLTNEHCSRWDRSSGKRSYQELSVSSHGCHLNGPFSSNLFTIPKQRSSSVSLTHH
AGLRRAGALPSHSLLNSSSHVPVSAGSLTNRSPIGFPDTTDFLTKPNIILHRSLGSVSSA
ADFHQYLRNSDSNLCSSCGHQILKYVSTCEPDGTDHPSEKSGEEDSSVFSKEPLNIVETQ
EEETMKKACRELFLEGDSHLMEEAQQPNIDQEVSLDPMLVEDYDSLIEKMNNWNFQIFEL
VEKMGEKSGRILSQVMYTLFQDTGLLETFKIPTQEFMNYFRALENGYRDIPYHNRVHATD
VLHAVWYLTTRPIPGLPQIHNNHETETKADSDGRLGSGQIAYISSKSCCIPDMSYGCLSS
NIPALELMALYVAAAMHDYDHPGRTNAFLVATNAPQAVLYNDRSVLENHHAASAWNLYLS
RPEYNFLLNLDHMEFKRFRFLVIEAILATDLKKHFDFLAEFNAKANDVNSNGIEWSSEND
RLLVCQVCIKLADINGPAKDRDLHLRWTEGIVNEFYEQGDEEATLGLPISPFMDRSSPQL
AKLQESFITHIVGPLCNSYDAAGLLPGQWIETEEGDDTESDDDDDDDDGGGEELDSDDEE
TEDNLNPKPQRRKGRRRIFCQLMHHLTENHKIWKEIIEEEEEKCKAEGNKLQVDNASLPQ
ADEIQVIEEADEEEEQMFE
NT seq
3300 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaagacgagcgcgagcgggacgcgccagccatgaggtccccgccgccgccgcca
gcctcggccgcctcgccccccgagagcctgcgcaacggctacgtgaagagctgcgtgagc
ccgctgcggcaggaccctccgcgcagcttcttcttccacctctgccgcttctgcaacgtg
gagccgccggcggcctcgctccgcgccggggcacgcctctcgctcggcgtcctggccgcc
tttgtcctggccgcgctgctgggcgcgaggcccgagcgctgggcggccgcggcagccggg
ctccggacgctgctgagcgcctgctcgctcagcctcagcccgctcttcagcatcgcctgt
gccttcttcttcctcacctgtttcctgacgcgcgcgcagcgcggcccgggccgcggcgcc
ggctcctggtggctgctggcgctgcccgcctgctgctacctgggcgacttcgcggcgtgg
cagtggtggtcgtggctgcgtggggagccggcggcggcgggccggctctgcctggtgctg
agctgcgtggggctgctgacgctcgcgccccgcgtgaggctgcggcacggcgtcctggtg
ctgctcttcgccggcctggtgtggtgggtgtccttctccggcctcggggctctgccgccc
gcgctcaggcctctgctgtcgtgcctggtcgggggcgcgggatgcctgctagccctgggc
ttggaccacttctttcacgtccggggagcctcccctccgccgcgctcggcgagtaccgcg
gaggaaaaagtgcctgtgatcagaccccggaggaggtccagctgcgtgtcgctgggagaa
agcgcagccggttactatggcagtggcaagatgttcaggagaccgtcgttgccttgtatt
tcccgagaacagatgatcctctgggactgggacttgaagcagtggtgtaaacctcattac
cagaattctggaggtggaaatggagttgatctttcagtgctaaatgaagctcgcaatatg
gtgtcagacctgctgattgacccaagccttcccccacaagtcatttcttctctgcggagt
atcagtagcttgatgggtgctttctcaggttcctgtaggccaaagattaattcttttaca
ccatttcctggattttatccctgctctgaagtagaagatccagttgagaaaggagatcga
aaacttcacaagggattgagtggcagaaccagtttcccaactccacagctgaggaggagc
tctggagcctcatcgttgctgactaatgagcactgttcaaggtgggatcgcagcagtggt
aagaggtcttaccaagaactcagtgtttcaagtcatggatgccacctaaatgggcctttt
agttcaaatctttttacaattccaaagcagaggtcatcgtctgtgtcactgacgcaccat
gcaggtctgagaagagctggtgctttgcccagccacagtcttctgaattcttcaagccat
gtaccagtgtctgctggctctctaactaatcgatcacccataggatttcctgataccact
gattttcttactaagccaaatattattttacatagatcactgggcagtgtatcaagtgca
gcagatttccatcagtaccttaggaactctgacagcaatctgtgtagcagctgtggacac
caaatactcaaatatgtttcaacatgtgaacccgatggtacagaccaccccagtgaaaaa
tcaggtgaagaagacagcagtgttttctcaaaagaaccattgaacattgtggaaacccaa
gaagaagagaccatgaagaaagcctgcagggagttatttttggaaggtgatagtcacctg
atggaagaggcacagcaaccaaatatcgatcaggaagtgtcactggatccaatgttagta
gaagattatgattcattaatagaaaagatgaacaactggaattttcagatttttgagctt
gtagaaaagatgggagaaaaatcaggaaggattctcagtcaggttatgtatactttattt
caagatactggtttattggaaacatttaaaattcccactcaagaatttatgaattatttt
cgtgccttagaaaatggctaccgggacattccatatcacaatcgtgtgcatgccacagat
gtcctacatgctgtttggtatttgacaacccgaccaattcctggcttacctcagatccat
aataaccatgaaacggaaaccaaagcagattcagatggtagacttggttctggacagatt
gcttacatttcttcgaagagttgctgtattccagatatgagttatggctgcctatcttca
aacatccctgcattagaattgatggctttgtatgtggcagctgccatgcacgattacgat
cacccaggaagaacaaatgcgtttctagtggctacaaatgcacctcaggcagttttatac
aatgacagatctgttctagagaatcatcatgctgcatcagcttggaatctgtatctttct
cgcccagagtacaacttcctccttaaccttgatcacatggaattcaagcggtttcgattt
ttagttatagaagcaatccttgctacagatctcaaaaaacattttgatttccttgcagaa
ttcaatgccaaggccaatgatgtaaatagtaacggtatagaatggagcagtgaaaacgat
cgcctcttggtctgccaggtgtgcatcaaattagcagatatcaatggcccagcaaaagat
cgggacctacatttgagatggacagaaggcattgtgaatgaattttatgagcagggagat
gaagaagcaaccctgggtctacctattagtcccttcatggatcgttcttctcctcaacta
gcaaaactccaagaatcttttatcacccacattgtgggccccctgtgcaactcctatgat
gctgctggcttgctgccgggtcagtggatagaaacagaagagggtgatgatacagaaagt
gatgatgatgatgatgatgatgatggtggtggtgaagaattagattcagatgatgaagaa
acagaagacaatctaaatcctaaaccacaaagaaggaaaggcaggcggcgaatattttgc
caactaatgcaccacctcactgaaaaccacaagatatggaaggaaatcatagaagaagaa
gaagaaaaatgtaaagctgaggggaacaaactgcaggtggataatgcctccttacctcag
gcagatgagattcaggttattgaagaagcagatgaagaggaagaacaaatgtttgaatga
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