Mus musculus (house mouse): 18746 Help Entry 18746             CDS       T01002                                  Symbol Pkm, Pk-2, Pk-3, Pk3, Pkm2 Name (RefSeq) pyruvate kinase, muscle   KO K00873   pyruvate kinase [EC:2.7.1.40] Organism mmu  Mus musculus (house mouse) Pathway mmu00010   Glycolysis / Gluconeogenesis mmu00620   Pyruvate metabolism mmu01100   Metabolic pathways mmu01200   Carbon metabolism mmu01230   Biosynthesis of amino acids mmu04922   Glucagon signaling pathway mmu04930   Type II diabetes mellitus mmu05165   Human papillomavirus infection mmu05203   Viral carcinogenesis mmu05230   Central carbon metabolism in cancer Module mmu_M00001   Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate mmu_M00002   Glycolysis, core module involving three-carbon compounds Brite KEGG Orthology (KO) [BR:mmu00001]  09100 Metabolism   09101 Carbohydrate metabolism    00010 Glycolysis / Gluconeogenesis     18746 (Pkm)    00620 Pyruvate metabolism     18746 (Pkm)  09150 Organismal Systems   09152 Endocrine system    04922 Glucagon signaling pathway     18746 (Pkm)  09160 Human Diseases   09161 Cancer: overview    05203 Viral carcinogenesis     18746 (Pkm)    05230 Central carbon metabolism in cancer     18746 (Pkm)   09172 Infectious disease: viral    05165 Human papillomavirus infection     18746 (Pkm)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     18746 (Pkm)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:mmu04131]     18746 (Pkm)   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:mmu04147]     18746 (Pkm) Enzymes [BR:mmu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.1  Phosphotransferases with an alcohol group as acceptor     2.7.1.40  pyruvate kinase      18746 (Pkm) Membrane trafficking [BR:mmu04131]  Autophagy   Chaperone mediated autophagy (CMA)    Selective cargos     18746 (Pkm) Exosome [BR:mmu04147]  Exosomal proteins   Proteins found in most exosomes    18746 (Pkm) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK PK_C HpcH_HpaI Motif Other DBs NCBI-GeneID:  18746 NCBI-ProteinID:  NP_001240812 MGI:  97591 Ensembl:  ENSMUSG00000032294 UniProt:  P52480 LinkDB All DBs Position 9:59563859..59586655 Genome browser AA seq 531 aa AA seqDB search MPKPHSEAGTAFIQTQQLHAAMADTFLEHMCRLDIDSAPITARNTGIICTIGPASRSVEM LKEMIKSGMNVARLNFSHGTHEYHAETIKNVREATESFASDPILYRPVAVALDTKGPEIR TGLIKGSGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGL ISLQVKEKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMV FASFIRKAADVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIE IPAEKVFLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIM LSGETAKGDYPLEAVRMQHLIAREAEAAMFHRLLFEELVRASSHSTDLMEAMAMGSVEAS YKCLAAALIVLTESGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDAVLN AWAEDVDLRVNLAMDVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPVP NT seq 1596 nt NT seq  +upstreamnt  +downstreamnt atgccgaagccacacagtgaagcagggactgccttcattcagacccagcagctccatgca gccatggctgacaccttcctggaacacatgtgccgcctggacattgactctgcccccatc acggcccgcaacactggcatcatttgtaccattgggcctgcttcccgatctgtggagatg ctgaaggagatgattaagtctggaatgaatgtggctcggctgaatttctctcatggaacc catgagtaccatgcagagaccatcaagaatgtccgtgaagccacagaaagctttgcatct gatcccattctctaccgtcctgttgcggtggctctggatacaaagggacctgagatccgg actggactcatcaagggcagcggcaccgctgaggtggagctgaagaagggagccactctg aagatcaccctggacaacgcttacatggagaagtgtgacgagaacatcctgtggctggac tacaagaacatctgcaaggtggtggaggtgggcagcaagatctacgtggacgatgggctc atctcactgcaggtgaaggagaaaggcgctgacttcctggtgacggaggtggagaatggt ggctccttgggcagcaagaagggcgtgaacctgccgggcgctgctgtggatctccccgct gtgtcggaaaaggacatccaggacctgaagtttggggtggagcaggatgtggacatggtg tttgcatctttcatccgcaaggcagccgacgtgcatgaagtcaggaaggtgctgggagag aagggcaagaacatcaagatcatcagcaaaatcgagaaccatgaaggcgtccgcaggttt gatgagatcttggaggccagtgatgggatcatggtggctcgtggtgacctgggcattgag attcctgcagagaaggtcttcctggctcagaagatgatgatcgggcgatgcaaccgagct gggaagcctgtcatctgtgccacacagatgctggagagcatgatcaagaagccacgcccc acccgtgctgaaggcagtgatgtggccaatgcagtcctggatggagcagactgcatcatg ctgtctggagaaacagccaagggggactaccctctggaggctgttcgcatgcagcacctg atagctcgggaggctgaggcagccatgttccaccgtctgctgtttgaagagcttgtgcga gcctccagtcactccacagacctcatggaggccatggccatgggcagcgtggaggcctct tataagtgtttagcagcagctttgatagttctcacggagtctggcaggagtgctcaccaa gtggccaggtaccgccctcgggctcctatcattgccgtgactcgaaatccccagactgct cgccaggcccatctgtaccgtggcatcttccctgtgctgtgtaaggatgccgtgctgaat gcctgggctgaggatgtcgaccttcgtgtaaacttggccatggatgttggcaaggcccga ggcttcttcaagaagggagatgtggtcattgtgctgaccgggtggcgccctggctctgga ttcaccaacaccatgcgtgtagtgcctgtaccttga

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