Mus musculus (house mouse): 18754
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Entry
18754 CDS
T01002
Symbol
Prkce, 5830406C15Rik, PKC[e], PKCepsilon, Pkce
Name
(RefSeq) protein kinase C, epsilon
KO
K18050
novel protein kinase C epsilon type [EC:
2.7.11.13
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04022
cGMP-PKG signaling pathway
mmu04071
Sphingolipid signaling pathway
mmu04270
Vascular smooth muscle contraction
mmu04371
Apelin signaling pathway
mmu04530
Tight junction
mmu04666
Fc gamma R-mediated phagocytosis
mmu04750
Inflammatory mediator regulation of TRP channels
mmu04925
Aldosterone synthesis and secretion
mmu04930
Type II diabetes mellitus
mmu04931
Insulin resistance
mmu04933
AGE-RAGE signaling pathway in diabetic complications
mmu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04371 Apelin signaling pathway
18754 (Prkce)
04071 Sphingolipid signaling pathway
18754 (Prkce)
04022 cGMP-PKG signaling pathway
18754 (Prkce)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
18754 (Prkce)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
18754 (Prkce)
09152 Endocrine system
04925 Aldosterone synthesis and secretion
18754 (Prkce)
09153 Circulatory system
04270 Vascular smooth muscle contraction
18754 (Prkce)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
18754 (Prkce)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
18754 (Prkce)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
18754 (Prkce)
04931 Insulin resistance
18754 (Prkce)
04933 AGE-RAGE signaling pathway in diabetic complications
18754 (Prkce)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
18754 (Prkce)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.13 protein kinase C
18754 (Prkce)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: AGC group
PKC family [OT]
18754 (Prkce)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
C1_1
C2
Pkinase_C
ABC1
PKC_C2
Kinase-like
PP_M1
Motif
Other DBs
NCBI-GeneID:
18754
NCBI-ProteinID:
NP_035234
MGI:
97599
Ensembl:
ENSMUSG00000045038
UniProt:
P16054
LinkDB
All DBs
Position
17:86472631..86965347
Genome browser
AA seq
737 aa
AA seq
DB search
MVVFNGLLKIKICEAVSLKPTAWSLRHAVGPRPQTFLLDPYIALNVDDSRIGQTATKQKT
NSPAWHDEFVTDVCNGRKIELAVFHDAPIGYDDFVANCTIQFEELLQNGSRHFEDWIDLE
PEGKVYVIIDLSGSSGEAPKDNEERVFRERMRPRKRQGAVRRRVHQVNGHKFMATYLRQP
TYCSHCRDFIWGVIGKQGYQCQVCTCVVHKRCHELIITKCAGLKKQETPDEVGSQRFSVN
MPHKFGIHNYKVPTFCDHCGSLLWGLLRQGLQCKVCKMNVHRRCETNVAPNCGVDARGIA
KVLADLGVTPDKITNSGQRRKKLAAGAESPQPASGNSPSEDDRSKSAPTSPCDQELKELE
NNIRKALSFDNRGEEHRASSATDGQLASPGENGEVRPGQAKRLGLDEFNFIKVLGKGSFG
KVMLAELKGKDEVYAVKVLKKDVILQDDDVDCTMTEKRILALARKHPYLTQLYCCFQTKD
RLFFVMEYVNGGDLMFQIQRSRKFDEPRSRFYAAEVTSALMFLHQHGVIYRDLKLDNILL
DAEGHCKLADFGMCKEGIMNGVTTTTFCGTPDYIAPEILQELEYGPSVDWWALGVLMYEM
MAGQPPFEADNEDDLFESILHDDVLYPVWLSKEAVSILKAFMTKNPHKRLGCVAAQNGED
AIKQHPFFKEIDWVLLEQKKIKPPFKPRIKTKRDVNNFDQDFTREEPILTLVDEAIIKQI
NQEEFKGFSYFGEDLMP
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
atggtagtgttcaatggccttcttaagatcaaaatctgcgaggcggtgagcttgaagccc
acagcctggtcgctgcgccatgcggtgggaccccggccacagacgttccttttggacccc
tacattgcccttaacgtggacgactcgcgcatcggccaaacagccaccaagcaaaagacc
aacagcccggcctggcacgatgagttcgtcaccgatgtgtgcaatgggcgcaagatcgag
ctggctgtctttcacgacgctcctatcggctacgacgacttcgtggccaactgcaccatc
cagttcgaggagctgctgcagaatgggagccgtcacttcgaggactggattgacctggag
ccagaaggaaaagtgtacgtgatcatcgatctctcgggatcatcgggtgaagcccctaaa
gacaatgaagaacgagtgttcagggagcgtatgcggccaaggaagcggcaaggggctgtc
aggcgcagggtccaccaggtcaatggccacaagttcatggccacctacttgcggcaaccc
acctactgctcccactgcagagatttcatctggggtgtcataggaaaacagggatatcaa
tgtcaagtttgcacttgcgttgtccacaagcgatgtcatgagctcattattacaaagtgc
gctgggctgaagaaacaggaaacccctgacgaggtgggctcccaacggttcagcgtcaac
atgccccacaagttcgggatccacaactacaaggtccccacgttctgtgaccactgtggg
tccctgctctggggcctcttgcggcagggcttgcagtgtaaagtctgcaaaatgaatgtt
caccggcgatgtgagaccaatgtggctcccaactgtggggtagacgccagaggaattgcc
aaagtgctggctgaccttggtgttactccagacaaaatcaccaacagtggccaaaggagg
aaaaagctcgctgctggtgctgagtccccacagccggcttctggaaactccccatctgaa
gacgaccgatccaagtcagcgcccacctccccttgtgaccaggaactaaaagaacttgaa
aacaacattcggaaggccttgtcatttgacaaccgaggagaggagcaccgagcgtcgtcg
gccaccgatggccagctggcaagccccggagagaacggggaagtccggccaggccaggcc
aagcgcttggggctggatgagttcaacttcatcaaggtgttgggcaaaggcagctttggc
aaggtcatgttggcggaactcaaaggcaaagatgaagtctacgctgtgaaggtcttgaag
aaggacgttatcctacaagacgatgatgtggactgcacaatgacagagaagaggattttg
gctctggctcggaaacacccttatctaacccaactctattgctgcttccagaccaaggac
cgcctcttcttcgtcatggaatatgtaaatggtggagacctcatgttccagattcagcgg
tcccgaaaatttgatgagcctcgttctcggttctatgccgcagaggtcacatcagccctc
atgtttctccaccagcacggagtgatctacagggatttgaaactggacaacatccttcta
gatgcagaaggccactgcaagctggctgactttgggatgtgcaaggaagggattatgaat
ggtgtgacaactaccaccttctgtgggactcctgactacatagctccagagatcctacag
gagttggagtacggcccctcagtggactggtgggccctgggggtgctgatgtacgagatg
atggctgggcagcccccctttgaagctgacaacgaggacgacttgttcgaatccatcctt
catgatgatgttctctatcctgtctggcttagcaaggaagctgtcagcatcctgaaagct
ttcatgaccaagaacccgcacaagcgcctgggctgtgtggcagcgcagaacggggaggac
gccatcaagcaacatccattcttcaaggagattgactgggtactgctggagcagaagaaa
atcaagccccccttcaagccgagaattaaaaccaaaagagatgtcaataactttgaccaa
gactttacgcgggaagagccaatacttacacttgtggatgaagcaatcattaagcagatc
aaccaggaagaattcaaaggcttctcctactttggtgaagacctgatgccctga
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