Mus musculus (house mouse): 18770
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Entry
18770 CDS
T01002
Symbol
Pklr, Pk-1, Pk1, R-PK
Name
(RefSeq) pyruvate kinase liver and red blood cell
KO
K12406
pyruvate kinase isozymes R/L [EC:
2.7.1.40
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00010
Glycolysis / Gluconeogenesis
mmu00620
Pyruvate metabolism
mmu01100
Metabolic pathways
mmu01200
Carbon metabolism
mmu01230
Biosynthesis of amino acids
mmu04910
Insulin signaling pathway
mmu04930
Type II diabetes mellitus
mmu04932
Non-alcoholic fatty liver disease
mmu04950
Maturity onset diabetes of the young
Module
mmu_M00001
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
mmu_M00002
Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
18770 (Pklr)
00620 Pyruvate metabolism
18770 (Pklr)
09160 Human Diseases
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
18770 (Pklr)
04950 Maturity onset diabetes of the young
18770 (Pklr)
04932 Non-alcoholic fatty liver disease
18770 (Pklr)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
18770 (Pklr)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.40 pyruvate kinase
18770 (Pklr)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of other body fluids (saliva and urine)
18770 (Pklr)
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SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK
PK_C
IMPDH
Motif
Other DBs
NCBI-GeneID:
18770
NCBI-ProteinID:
NP_001093249
MGI:
97604
Ensembl:
ENSMUSG00000041237
UniProt:
Q3UEI4
Q3UEH4
E9Q509
LinkDB
All DBs
Position
3:89043429..89054122
Genome browser
AA seq
543 aa
AA seq
DB search
MEGPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSII
ATIGPASRSVDRLKEMIKAGMNIARLNFSHGSHEYHAESIANIREAAESFATSPLSYRPV
AIALDTKGPEIRTGVLQGGPESEVEIVKGSQVLVTVDPKFRTRGDAKTVWVDYHNITQVV
AVGGRIYIDDGLISLVVRKIGPEGLVTEVEHGGFLGNRKGVNLPNAEVDLPGLSEQDLLD
LRFGVEHNVDIIFASFVRKASDVVAVRDALGPEGRGIKIISKIENHEGVKKFDEILEVSD
GIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKARPTRAETSDV
ANAVLDGADCIMLSGETAKGSFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDP
TEVTAIGAVEASFKCCAAAIIVLTKTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLSRG
VFPLLYREPPEAVWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVL
TIS
NT seq
1632 nt
NT seq
+upstream
nt +downstream
nt
atggaagggccagcaggatacctgagacgtgccagtgtggcccagctgacccaggagctg
ggcactgccttcttccagcagcagcaactgcccgcagctatggcggacaccttcctggaa
cacctctgccttctggatatcgactcagagcctgtggccgctaggagcaccagcatcatt
gccaccatcgggccggcgtcacgctctgtggaccgcctcaaggagatgatcaaggcaggg
atgaacattgcacgactcaacttctcccatggctcccatgagtaccatgcagagtccatc
gccaacattcgggaggcggctgaaagctttgcaacctccccactcagctacagacccgtg
gccatcgccctggacaccaagggtcccgagatacgcactggagtcctgcaggggggtcca
gagtcggaggtggaaattgtgaagggttcacaggtgctggtgactgtggatccgaagttc
cggacaaggggcgatgcaaagacagtgtgggtggactaccacaatatcacccaggtcgtt
gcagtggggggccgcatctacattgacgacgggctcatctccttagtggtgcggaaaatt
ggcccagagggactggtgaccgaagtggaacacggtggtttcttgggcaacaggaagggt
gtgaacttgccaaatgccgaggtggacctgcctgggctatcagagcaagatcttttggat
ctgcgcttcggggtggagcataatgtggacatcatctttgcctcctttgtacgaaaagcc
agtgatgtggtggcagtccgagatgccctagggccagaaggacggggcatcaaaattatc
agcaaaatcgagaaccatgaaggcgtgaagaagtttgatgagatcctagaagtgagcgat
ggcatcatggtggctcggggtgaccttggcattgagatcccagcagagaaggttttcttg
gctcagaagatgatgattggacgctgcaacctggctggcaagcctgtcgtttgtgccaca
cagatgctggagagcatgatcactaaggctcgaccaactcgggcggagacaagcgatgtg
gccaatgctgtgctggatggggctgactgtatcatgctgtctggagagaccgccaaaggc
agtttccccgtggaggctgtaaagatgcaacatgcgattgcccgggaggcagaggccgct
gtgtaccaccgccagttgtttgaggagctacgccgggcagcgccgctgagccgtgaccca
accgaggtcactgcaattggagccgtggaggcttccttcaagtgctgtgccgcagccatc
attgtgctgacaaagactggccgctcagctcagcttctgtctcgctaccgacctcgggct
gctgtcattgctgtgactcgttctgcccaggctgcccgacaggtccacctgtcccgagga
gtcttccccttgctctaccgtgagcctccagaggctgtctgggcagatgatgtggaccga
agggtccaatttggcatcgaaagtggaaagcttcgtggcttcctccgagttggtgatctg
gtgattgtggtgacaggctggcgacctggctctggctataccaacattatgcgggtgctg
accatatcctga
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