Mus musculus (house mouse): 18783
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Entry
18783 CDS
T01002
Symbol
Pla2g4a, Pla2g4, cPLA2, cPLA2-alpha, cPLA2alpha
Name
(RefSeq) cytosolic phospholipase A2 isoform 1
KO
K16342
cytosolic phospholipase A2 [EC:
3.1.1.4
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00564
Glycerophospholipid metabolism
mmu00565
Ether lipid metabolism
mmu00590
Arachidonic acid metabolism
mmu00591
Linoleic acid metabolism
mmu00592
alpha-Linolenic acid metabolism
mmu01100
Metabolic pathways
mmu04010
MAPK signaling pathway
mmu04014
Ras signaling pathway
mmu04072
Phospholipase D signaling pathway
mmu04217
Necroptosis
mmu04270
Vascular smooth muscle contraction
mmu04370
VEGF signaling pathway
mmu04611
Platelet activation
mmu04664
Fc epsilon RI signaling pathway
mmu04666
Fc gamma R-mediated phagocytosis
mmu04724
Glutamatergic synapse
mmu04726
Serotonergic synapse
mmu04730
Long-term depression
mmu04750
Inflammatory mediator regulation of TRP channels
mmu04912
GnRH signaling pathway
mmu04913
Ovarian steroidogenesis
mmu04921
Oxytocin signaling pathway
mmu05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09103 Lipid metabolism
00564 Glycerophospholipid metabolism
18783 (Pla2g4a)
00565 Ether lipid metabolism
18783 (Pla2g4a)
00590 Arachidonic acid metabolism
18783 (Pla2g4a)
00591 Linoleic acid metabolism
18783 (Pla2g4a)
00592 alpha-Linolenic acid metabolism
18783 (Pla2g4a)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
18783 (Pla2g4a)
04014 Ras signaling pathway
18783 (Pla2g4a)
04370 VEGF signaling pathway
18783 (Pla2g4a)
04072 Phospholipase D signaling pathway
18783 (Pla2g4a)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
18783 (Pla2g4a)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
18783 (Pla2g4a)
04664 Fc epsilon RI signaling pathway
18783 (Pla2g4a)
04666 Fc gamma R-mediated phagocytosis
18783 (Pla2g4a)
09152 Endocrine system
04912 GnRH signaling pathway
18783 (Pla2g4a)
04913 Ovarian steroidogenesis
18783 (Pla2g4a)
04921 Oxytocin signaling pathway
18783 (Pla2g4a)
09153 Circulatory system
04270 Vascular smooth muscle contraction
18783 (Pla2g4a)
09156 Nervous system
04724 Glutamatergic synapse
18783 (Pla2g4a)
04726 Serotonergic synapse
18783 (Pla2g4a)
04730 Long-term depression
18783 (Pla2g4a)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
18783 (Pla2g4a)
09160 Human Diseases
09161 Cancer: overview
05231 Choline metabolism in cancer
18783 (Pla2g4a)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.1 Carboxylic-ester hydrolases
3.1.1.4 phospholipase A2
18783 (Pla2g4a)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PLA2_B
C2
cPLA2_C2
Motif
Other DBs
NCBI-GeneID:
18783
NCBI-ProteinID:
NP_032895
MGI:
1195256
Ensembl:
ENSMUSG00000056220
UniProt:
P47713
Q3UMQ1
LinkDB
All DBs
Position
1:complement(149705369..149837041)
Genome browser
AA seq
748 aa
AA seq
DB search
MSFIDPYQHIIVEHQYSHKFTVVVLRATKVTKGTFGDMLDTPDPYVELFISTTPDSRKRT
RHFNNDINPVWNETFEFILDPNQENVLEITLMDANYVMDETLGTATFPVSSMKVGEKKEV
PFIFNQVTEMILEMSLEVCSCPDLRFSMALCDQEKTFRQQRKENIKENMKKLLGPKKSEG
LYSTRDVPVVAILGSGGGFRAMVGFSGVMKALYESGILDCATYIAGLSGSTWYMSTLYSH
PDFPEKGPEEINEELMKNVSHNPLLLLTPQKVKRYVESLWKKKSSGQPVTFTDIFGMLIG
ETLIQNRMSMTLSSLKEKVNAARCPLPLFTCLHVKPDVSELMFADWVEFSPYEIGMAKYG
TFMAPDLFGSKFFMGTVVKKYEENPLHFLMGVWGSAFSILFNRVLGVSGSQNKGSTMEEE
LENITAKHIVSNDSSDSDDEAQGPKGTENEEAEKEYQSDNQASWVHRMLMALVSDSALFN
TREGRAGKVHNFMLGLNLNTSYPLSPLRDFSSQDSFDDELDAAVADPDEFERIYEPLDVK
SKKIHVVDSGLTFNLPYPLILRPQRGVDLIISFDFSARPSDTSPPFKELLLAEKWAKMNK
LPFPKIDPYVFDREGLKECYVFKPKNPDVEKDCPTIIHFVLANINFRKYKAPGVLRETKE
EKEIADFDIFDDPESPFSTFNFQYPNQAFKRLHDLMYFNTLNNIDVIKDAIVESIEYRRQ
NPSRCSVSLSNVEARKFFNKEFLSKPTV
NT seq
2247 nt
NT seq
+upstream
nt +downstream
nt
atgtctttcatagatccttatcagcacattatagtggaacaccagtactcccataagttt
actgttgtggttctacgtgccaccaaagtaaccaaggggacctttggcgatatgctggac
actccagatccttatgtggaacttttcatctctacaacccctgacagcaggaagcgaacg
agacacttcaataatgatataaaccccgtgtggaatgagacctttgagttcattttggat
cctaatcaggaaaatgttttggagatcacactgatggatgccaactacgtcatggatgaa
accctaggcacagctacattccctgtatcttcaatgaaagtgggagagaagaaagaagtc
ccttttattttcaaccaagtcactgaaatgattctggaaatgtctctggaagtttgttca
tgcccagacctacggttcagcatggcactgtgtgatcaggagaaaactttcagacagcag
aggaaagagaacataaaagagaacatgaagaaacttttgggtccaaaaaagagtgagggg
ctttattccacacgtgatgtgccggtggtggccattttgggttcaggtgggggtttccgg
gccatggtgggattctctggtgtgatgaaggcactgtatgagtcggggattttggactgt
gctacatacattgctggtctttctggatccacatggtacatgtcaaccttgtactctcac
cccgattttccagagaaaggtcccgaggagattaatgaagagctaatgaaaaatgtcagc
cacaaccctctcttacttcttacaccacagaaagttaaaagatacgttgagtctttatgg
aagaagaaaagttctggccagcctgtcacctttactgacatctttgggatgctaatagga
gaaacactaattcaaaataggatgagcatgaccctgagtagtttgaaggaaaaggtcaat
gccgcccggtgtcctttgcctctcttcacgtgtctccacgtcaaacctgatgtgtcagag
ctgatgtttgccgattgggtggaatttagtccatatgagattggcatggcaaaatatggt
acctttatggctcctgacctatttggaagcaagttttttatgggaacagttgtaaaaaaa
tatgaagaaaaccccttgcatttcttgatgggtgtctggggcagtgccttttctatactg
ttcaacagagttttgggagtttctggctcacagaataaaggctctacaatggaagaggaa
ttagaaaatattacagcaaagcacatcgtgagtaatgacagctccgacagtgatgatgag
gctcaaggacccaaaggcaccgagaatgaagaagctgaaaaagagtaccaaagcgacaac
caagcaagttgggtccatcggatgctaatggccttggtgagcgactcggctttattcaat
acccgagaaggacgtgccggaaaggtgcataacttcatgctgggcttgaatctcaacaca
tcatatccactgtctcccctgagagacttcagctctcaggattccttcgatgacgagctc
gacgcagcggtagcagatccagatgaatttgaacgaatatatgaaccactggatgtcaaa
agtaagaagattcatgtggtagatagtgggctcacatttaacctgccatatcccttgatt
cttcgacctcagagaggtgtggatcttatcatctcctttgacttttctgcaaggccgagt
gacaccagtccccctttcaaggaacttctgcttgcagagaagtgggcgaaaatgaacaag
cttccctttccaaagatcgatccttatgtgtttgatcgggaaggattaaaggaatgctat
gtttttaaacctaagaatcctgatgtggagaaggattgcccaaccattatccactttgtt
ctggccaacatcaacttcagaaagtacaaggccccaggtgttctaagggaaaccaaagaa
gagaaagaaattgctgactttgacatttttgatgaccccgaatcgccattttcaaccttc
aactttcagtatcccaatcaagcattcaaaaggcttcacgatttgatgtacttcaacaca
ctgaacaacattgatgtgataaaggatgccattgttgagagcattgaatacagaagacag
aacccatctcgttgctctgtttccctcagtaatgttgaagcaagaaaattcttcaataag
gagtttctaagtaaacccactgtgtaa
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