KEGG   Mus musculus (house mouse): 18802
Entry
18802             CDS       T01002                                 
Symbol
Plcd4, 4921507K24Rik
Name
(RefSeq) phospholipase C, delta 4
  KO
K05857  phosphatidylinositol phospholipase C, delta [EC:3.1.4.11]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu00562  Inositol phosphate metabolism
mmu01100  Metabolic pathways
mmu04020  Calcium signaling pathway
mmu04070  Phosphatidylinositol signaling system
mmu04919  Thyroid hormone signaling pathway
mmu04933  AGE-RAGE signaling pathway in diabetic complications
Module
mmu_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    18802 (Plcd4)
 09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    18802 (Plcd4)
   04070 Phosphatidylinositol signaling system
    18802 (Plcd4)
 09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    18802 (Plcd4)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    18802 (Plcd4)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:mmu04131]
    18802 (Plcd4)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     18802 (Plcd4)
Membrane trafficking [BR:mmu04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    18802 (Plcd4)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    18802 (Plcd4)
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y EF-hand_like C2 EF-hand_10 PH PH_12 EF-hand_7 EF-hand_1 EF-hand_6 EF-hand_5 GDPD EF-hand_PLCG2 Wap1 EF-hand_15 DUF3939 DUF2057
Other DBs
NCBI-GeneID: 18802
NCBI-ProteinID: NP_683739
MGI: 107469
Ensembl: ENSMUSG00000026173
UniProt: Q8K3R3
LinkDB
Position
1:74581175..74605137
AA seq 807 aa
MTSQIQDLLATDQDLLLMQEGTMMRKVRTKSWKKLRYFRLQNDGMTVWHGSQPESMPKPT
FSISDVERIRKGQDSELLRYLVEEFPLEQGFTVVFHGRRPNLDLVANSVEEAQIWMRGLQ
LLVDLVASMDHQEQMDQMLNEWFQQADRNQDGRMSFREAQRLLLLMNVEMDEEYAFSLFQ
EADVTQSDDLGSEEFVQFYKALTKRTEIEEIFEDFSSDKQKLTLLEFVDFLRKEQKEKDH
APDLALELIDRYEPSENGRLLHVLSKDGFLKYLCSKDGNIFNSDCLPIYQDMTQPLSHYY
INSSHNTYLVGDQLCGQSSVEGYIRALKRGCRCVEVDTWDGPDGEPVVYHGHTLTSRILF
KDVLATLAQYAFQSSDYPLILSLENHCTWEQQRTMAHHLTEILGEQLLRNTLEGLLVDSM
PSPEQLRGKILVKGKKLRTIEVDKEEEEEEEEEELEKDEGPDLDPASPELDTQPQPETQG
QAAGNKKERKKKVMKCPMSCLLICGHVMAQAPSSIPESILLSKQFLLLSSTTIMCPDLSA
LVVYLRTVPFCSFTHSKENYHIYDISSFSESKAKNLIKEAGNEFVQHNARQLCRVYPSGL
RTDSSNFNPQEHWNVGCQMVAMNMQTAGSAMDICDGLFRQNGGSGYVLKPEFLRDTQSSF
NPERPISLYKAQILVVQVISGQQLPKVDKTKETTVVDPLVKVELYGVPEDTKEQETSHVE
NNGINPYWGETFYFRLQVPELAMLRFVVKDYSRKSRNNFIGQYTLPWTCMKQGYRHVSLL
SRDGTSLNPASIFVYTCMQEDLDMDEP
NT seq 2424 nt   +upstreamnt  +downstreamnt
atgacatctcagattcaagacctactagccactgatcaggacctgctgctgatgcaagaa
ggcacaatgatgcgcaaggtgaggaccaaaagctggaagaagctaagatacttcagactt
cagaatgacggcatgacagtctggcatggaagtcaaccagaaagcatgcccaagcccact
ttttcgatctctgatgtggagaggatacgtaaggggcaggattctgagttgttgcgctat
ctggtggaggagtttcccctggagcaagggttcaccgttgtctttcatgggcgccgcccc
aacctggacctagtggccaacagtgttgaagaggcccagatttggatgcgaggactccag
ctgttggtggatcttgttgccagcatggaccaccaggagcaaatggatcaaatgttgaat
gagtggttccagcaagcagacagaaaccaggatggccggatgagtttcagagaagctcaa
cggctgctgcttctgatgaacgtggaaatggatgaagagtacgccttcagtcttttccag
gaggcagatgttacccagtctgatgatctggggtcggaagaatttgtacagttctataag
gccctgactaagcgcactgagattgaagaaatatttgaggacttctcatctgacaaacag
aagctgaccttgctggaatttgtggatttccttagaaaggaacagaaagaaaaagaccat
gctcctgacctcgctctggaactcattgaccgctatgagccttctgagaatggccgattg
ctgcatgtgctgagcaaggatggcttcctcaagtacctctgctcgaaggatggaaacatc
ttcaacagtgactgcctccctatctaccaggatatgactcagcctctgagccactactac
attaactcttctcacaacacctacctagtgggggaccagctttgcggccagagcagcgtt
gaaggatacatacgggccttgaaacgggggtgccgctgtgtggaggtggacacgtgggat
ggacctgatggagagcctgttgtttatcatgggcataccctgacctctcgcatcctattc
aaagatgtgttggcaactctcgcgcaatatgccttccagtcatcagactaccctctcatc
ttgtctctggaaaaccactgcacctgggaacagcagaggaccatggcacaccatctgacc
gagatcctgggagagcagctgctgaggaacaccctagagggattgctggttgacagcatg
ccctcgccagagcagcttcgggggaagatcttggtgaaaggaaagaagttaagaacaatt
gaagttgacaaggaagaagaagaagaagaagaagaagaagagctggagaaagatgagggg
ccagatctggacccagcctcccctgagttggacactcaacctcagcctgagacccagggg
caggccgctgggaacaagaaggagaggaagaagaaggttatgaagtgtccgatgtcttgt
ctgcttatctgtggtcatgttatggcccaggctcctagttccattcctgagtccattctc
ttgtcaaagcagtttcttctcctgagttccacaaccatcatgtgcccagacctatctgcc
ctggttgtctacttgaggactgtccccttctgcagcttcactcattccaaagaaaactac
cacatctatgacatttcatccttttctgagtccaaggccaagaacctcatcaaggaggca
ggcaacgagtttgtacagcacaatgccagacagttatgccgcgtgtatcccagtggtctg
aggacagattcatccaactttaacccccaggaacactggaatgtaggctgccagatggtg
gctatgaatatgcagactgcaggaagtgcaatggatatctgtgatgggctcttccgccag
aatggtggctctggctatgtgctgaagccagaattcctgagagatacccagagttcattc
aatcctgagaggccaattagtctttataaggcccagatccttgtagtccaggtgatcagt
ggccaacaactccccaaagtggataaaaccaaagagacaaccgttgtggatccactggtg
aaagtagagctctatggtgttcctgaagacacaaaggagcaagagaccagccatgtggag
aacaatggtattaatccatactggggggagactttctatttccggctccaggtacctgaa
cttgctatgttgcgttttgtggtaaaggattatagcaggaaatcccgaaataactttatt
ggccaatacaccctaccttggacctgtatgaaacaaggctaccgacatgtatccttgctc
tccagagatggcactagcctcaatccagcttccatctttgtatacacctgcatgcaggaa
gacctggatatggatgagccctga

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