KEGG   Mus musculus (house mouse): 19046
Entry
19046             CDS       T01002                                 
Symbol
Ppp1cb, 1200010B19
Name
(RefSeq) protein phosphatase 1 catalytic subunit beta
  KO
K06269  serine/threonine-protein phosphatase PP1 catalytic subunit [EC:3.1.3.16]
Organism
mmu  Mus musculus (house mouse)
Pathway
mmu03015  mRNA surveillance pathway
mmu04022  cGMP-PKG signaling pathway
mmu04024  cAMP signaling pathway
mmu04114  Oocyte meiosis
mmu04218  Cellular senescence
mmu04261  Adrenergic signaling in cardiomyocytes
mmu04270  Vascular smooth muscle contraction
mmu04390  Hippo signaling pathway
mmu04510  Focal adhesion
mmu04611  Platelet activation
mmu04720  Long-term potentiation
mmu04728  Dopaminergic synapse
mmu04750  Inflammatory mediator regulation of TRP channels
mmu04810  Regulation of actin cytoskeleton
mmu04910  Insulin signaling pathway
mmu04921  Oxytocin signaling pathway
mmu04931  Insulin resistance
mmu05031  Amphetamine addiction
mmu05034  Alcoholism
mmu05168  Herpes simplex virus 1 infection
mmu05205  Proteoglycans in cancer
mmu05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:mmu00001]
 09120 Genetic Information Processing
  09122 Translation
   03015 mRNA surveillance pathway
    19046 (Ppp1cb)
 09130 Environmental Information Processing
  09132 Signal transduction
   04390 Hippo signaling pathway
    19046 (Ppp1cb)
   04024 cAMP signaling pathway
    19046 (Ppp1cb)
   04022 cGMP-PKG signaling pathway
    19046 (Ppp1cb)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    19046 (Ppp1cb)
   04218 Cellular senescence
    19046 (Ppp1cb)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    19046 (Ppp1cb)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    19046 (Ppp1cb)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    19046 (Ppp1cb)
  09152 Endocrine system
   04910 Insulin signaling pathway
    19046 (Ppp1cb)
   04921 Oxytocin signaling pathway
    19046 (Ppp1cb)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    19046 (Ppp1cb)
   04270 Vascular smooth muscle contraction
    19046 (Ppp1cb)
  09156 Nervous system
   04728 Dopaminergic synapse
    19046 (Ppp1cb)
   04720 Long-term potentiation
    19046 (Ppp1cb)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    19046 (Ppp1cb)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    19046 (Ppp1cb)
  09172 Infectious disease: viral
   05168 Herpes simplex virus 1 infection
    19046 (Ppp1cb)
  09165 Substance dependence
   05031 Amphetamine addiction
    19046 (Ppp1cb)
   05034 Alcoholism
    19046 (Ppp1cb)
  09166 Cardiovascular disease
   05415 Diabetic cardiomyopathy
    19046 (Ppp1cb)
  09167 Endocrine and metabolic disease
   04931 Insulin resistance
    19046 (Ppp1cb)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins [BR:mmu01009]
    19046 (Ppp1cb)
  09182 Protein families: genetic information processing
   03021 Transcription machinery [BR:mmu03021]
    19046 (Ppp1cb)
   03019 Messenger RNA biogenesis [BR:mmu03019]
    19046 (Ppp1cb)
   03041 Spliceosome [BR:mmu03041]
    19046 (Ppp1cb)
Enzymes [BR:mmu01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.3  Phosphoric-monoester hydrolases
    3.1.3.16  protein-serine/threonine phosphatase
     19046 (Ppp1cb)
Protein phosphatases and associated proteins [BR:mmu01009]
 Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    Catalytic subunits
     19046 (Ppp1cb)
Transcription machinery [BR:mmu03021]
 Eukaryotic type
  RNA polymerase II system
   Other transcription-related factors
    Transcription termination factor
     19046 (Ppp1cb)
Messenger RNA biogenesis [BR:mmu03019]
 Eukaryotic type
  mRNA processing factors
   3' end processing
    Cleavage and polyadenylation specificity factor (CPSF) complex
     19046 (Ppp1cb)
Spliceosome [BR:mmu03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   Other SAPs
    19046 (Ppp1cb)
SSDB
Motif
Pfam: Metallophos STPPase_N
Other DBs
NCBI-GeneID: 19046
NCBI-ProteinID: NP_766295
MGI: 104871
Ensembl: ENSMUSG00000014956
UniProt: P62141
LinkDB
Position
5:32616192..32651057
AA seq 327 aa
MADGELNVDSLITRLLEVRGCRPGKIVQMTEAEVRGLCIKSREIFLSQPILLELEAPLKI
CGDIHGQYTDLLRLFEYGGFPPEANYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLL
RGNHECASINRIYGFYDECKRRFNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQ
SMEQIRRIMRPTDVPDTGLLCDLLWSDPDKDVQGWGENDRGVSFTFGADVVSKFLNRHDL
DLICRAHQVVEDGYEFFAKRQLVTLFSAPNYCGEFDNAGGMMSVDETLMCSFQILKPSEK
KAKYQYGGLNSGRPVTPPRTANPPKKR
NT seq 984 nt   +upstreamnt  +downstreamnt
atggcggacggggagctgaacgtggacagcctcatcacccgcctgctggaggtacgagga
tgtcgtccaggaaagattgtacaaatgactgaagcagaagtccgagggttgtgtatcaag
tctcgtgaaatctttctcagccagcctattcttttggaattggaagcaccactgaagatt
tgtggagacattcatggacaatatacagacttactaagattatttgaatatggaggtttt
ccaccagaagccaactatcttttcttaggagattatgtggacagaggaaagcagtctttg
gaaaccatctgtttgctattggcttacaaaatcaaatacccggagaacttctttcttcta
agaggaaaccatgagtgtgctagcatcaatcgcatttatggattctacgatgagtgtaaa
cgaagatttaatattaaattgtggaagacattcactgattgttttaactgtctgcctata
gctgctattgttgatgagaaaatcttctgttgtcatggaggactgtcaccagacctacaa
tctatggaacagattcggagaattatgagacccactgacgtacctgatacaggtttgctt
tgtgacttactgtggtccgacccagataaggatgtgcaaggctggggagaaaatgaccgt
ggtgtttcttttacttttggagctgatgtagtcagtaaatttctgaatcgtcatgattta
gacttgatttgtcgagctcatcaggtggtggaagacggatatgaattttttgctaaacga
cagttggtaaccttattttctgccccaaattactgtggcgagtttgacaatgctggtggt
atgatgagtgtggatgagactttgatgtgttcattccagatattgaaaccatctgaaaag
aaagctaagtaccagtatggtgggctgaattctggacgtcctgtcactccgcctcgaaca
gctaatccaccgaagaaaaggtga

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