Mus musculus (house mouse): 19877
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Entry
19877 CDS
T01002
Symbol
Rock1, 1110055K06Rik, Rock-I
Name
(RefSeq) Rho-associated coiled-coil containing protein kinase 1
KO
K04514
Rho-associated protein kinase 1 [EC:
2.7.11.39
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04022
cGMP-PKG signaling pathway
mmu04024
cAMP signaling pathway
mmu04062
Chemokine signaling pathway
mmu04071
Sphingolipid signaling pathway
mmu04270
Vascular smooth muscle contraction
mmu04350
TGF-beta signaling pathway
mmu04360
Axon guidance
mmu04510
Focal adhesion
mmu04520
Adherens junction
mmu04530
Tight junction
mmu04611
Platelet activation
mmu04670
Leukocyte transendothelial migration
mmu04810
Regulation of actin cytoskeleton
mmu04921
Oxytocin signaling pathway
mmu05135
Yersinia infection
mmu05163
Human cytomegalovirus infection
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
19877 (Rock1)
04071 Sphingolipid signaling pathway
19877 (Rock1)
04024 cAMP signaling pathway
19877 (Rock1)
04022 cGMP-PKG signaling pathway
19877 (Rock1)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04510 Focal adhesion
19877 (Rock1)
04520 Adherens junction
19877 (Rock1)
04530 Tight junction
19877 (Rock1)
09142 Cell motility
04810 Regulation of actin cytoskeleton
19877 (Rock1)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
19877 (Rock1)
04670 Leukocyte transendothelial migration
19877 (Rock1)
04062 Chemokine signaling pathway
19877 (Rock1)
09152 Endocrine system
04921 Oxytocin signaling pathway
19877 (Rock1)
09153 Circulatory system
04270 Vascular smooth muscle contraction
19877 (Rock1)
09158 Development and regeneration
04360 Axon guidance
19877 (Rock1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
19877 (Rock1)
05206 MicroRNAs in cancer
19877 (Rock1)
05205 Proteoglycans in cancer
19877 (Rock1)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
19877 (Rock1)
09171 Infectious disease: bacterial
05135 Yersinia infection
19877 (Rock1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
19877 (Rock1)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
mmu03036
]
19877 (Rock1)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.39 ROCK-subfamily protein kinase
19877 (Rock1)
Protein kinases [BR:
mmu01001
]
Serine/threonine kinases: AGC group
DMPK family [OT]
19877 (Rock1)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
19877 (Rock1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Rho_Binding
PH
C1_1
Pkinase_C
APH
Motif
Other DBs
NCBI-GeneID:
19877
NCBI-ProteinID:
NP_033097
MGI:
107927
Ensembl:
ENSMUSG00000024290
UniProt:
P70335
Q3UE22
LinkDB
All DBs
Position
18:complement(10064401..10182225)
Genome browser
AA seq
1354 aa
AA seq
DB search
MSTGDSFETRFEKIDNLLRDPKSEVNSDCLLDGLDALVYDLDFPALRKNKNIDNFLSRYK
DTINKIRDLRMKAEDYEVVKVIGRGAFGEVQLVRHKSTRKVYAMKLLSKFEMIKRSDSAF
FWEERDIMAFANSPWVVQLFYAFQDDRYLYMVMEYMPGGDLVNLMSNYDVPEKWARFYTA
EVVLALDAIHSMGFIHRDVKPDNMLLDKSGHLKLADFGTCMKMNKEGMVRCDTAVGTPDY
ISPEVLKSQGGDGYYGRECDWWSVGVFLYEMLVGDTPFYADSLVGTYSKIMNHKNSLTFP
DDNDISKEAKNLICAFLTDREVRLGRNGVEEIKRHLFFKNDQWAWETLRDTVAPVVPDLS
SDIDTSNFDDLEEDKGDEETFPIPKAFVGNQLPFVGFTYYSNRRYLPSANASENRSSSNV
DKSLQESLQKTIYKLEEQLHNEMQLKDEMEQKCRTSNLKLDKIMKELDEEGNQRRNLESA
VSQIEKEKMLLQHRINEYQRKVEQENEKRRNIENEVSTLKDQLEDLRKASQTSQLANEKL
TQLQKQLEEANDLLRTESDTAVRLRKSHTEMSKSISQLESLNRELQERNRILENSKSQAD
KDYYQLQAVLEAERRDRGHDSEMIGDLQARITSLQEEVKHLKHNLERVEGERKEAQDMLN
HSEKEKNNLEIDLNYKLKSIQQRLEQEVNEHKVTKARLTDKHQSIEEAKSVAMCEMEKKL
KEEREAREKAENRVVETEKQCSMLDVDLKQSQQKLEHLTENKERMEDEVKNLALQLEQES
NKRLLLQNELKTQAFEADNLKGLEKQMKQEINTLLEAKRLLEFELAQLTKQYRGNEGQMR
ELQDQLEAEQYFSTLYKTQVKELKEEIEEKNRENLRKIQELQSEKETLSTQLDLAETKAE
SEQLARGILEEQYFELTQESKKAASRNRQEITDKDHTVSRLEETNSVLTKDIEMLRKENE
ELNERMRTAEEEYKLKKEEEINNLKAAFEKNISTERTLKTQAVNKLAEIMNRKDFKIDRK
KANTQDLRKKEKENRKLQLELNQEREKFNQMVVKHQKELNDMQAQLVEECTHRNELQMQL
ASKESDIEQLRAKLLDLSDSTSVASFPSADETDGNLPESRIEGWLSVPNRGNIKRYGWKK
QYVVVSSKKILFYNDEQDKEQSSPSMVLDIDKLFHVRPVTQGDVYRAETEEIPKIFQILY
ANEGECRKDIEVEPVQQGEKTNFQNHKGHEFIPTLYHFPANCEACAKPLWHVFKPPPALE
CRRCHVKCHRDHLDKKEDLISPCKVSYDVTSARDMLLLACSQDEQKKWVTHLVKKIPKNP
PSGFVRASPRTLSTRSTANQSFRKVVKNTSGKTS
NT seq
4065 nt
NT seq
+upstream
nt +downstream
nt
atgtcgactggggacagttttgagactcggtttgaaaaaatcgacaacctgctgcgggat
cccaaatcggaagtgaattcagattgtttgctggatggattggatgccctggtttatgat
ttggattttcctgccttaagaaaaaacaaaaatattgacaactttctaagcagatataaa
gacacaataaataaaattagagatttacggatgaaagcagaagattatgaagtggtaaag
gtaatcggcagaggtgcatttggagaagttcaattggtgaggcataaatccactaggaag
gtttatgctatgaagctgctcagcaaatttgaaatgattaagagatcggattctgctttt
ttctgggaagaaagggacatcatggcgtttgccaatagtccttgggttgttcagcttttt
tatgcattccaagatgaccggtatctctacatggtgatggagtacatgcctggcggagac
cttgtcaacctgatgagcaactatgacgtgcctgaaaaatgggcaagattctatactgca
gaagtagttcttgcattggatgcaatccattccatgggttttattcatagagatgtaaag
cctgataacatgctgctggataagtctggacatttgaagttagcagattttggtacttgt
atgaagatgaataaggaaggtatggtacgatgtgacacagcagttggaacacctgattat
atctcacccgaagtattaaaatcccaaggcggtgatggctattatggacgagagtgtgac
tggtggtcagttggggtatttctatatgaaatgctcgtaggtgacacacctttctatgca
gattctttggttgggacttacagtaaaattatgaaccataaaaattcacttactttccct
gatgataatgacatatcaaaagaggcaaaaaatctcatttgtgccttccttacagacaga
gaagtgagattgggcagaaatggtgtagaggaaatcaaacgtcatctcttcttcaaaaat
gatcagtgggcttgggaaacgctccgagacactgtagcaccagttgtgcctgatttaagt
agtgacattgatactagtaattttgatgacttagaagaagataaaggagatgaagaaaca
tttcctattccaaaagcttttgttggcaatcagctaccttttgtaggatttacatattat
agcaatcgtagatacttaccttcagcaaatgccagtgagaacagatctagctccaatgtg
gataaaagcttgcaggaaagtttacagaaaacaatctacaagcttgaagagcaactgcat
aatgaaatgcaattaaaagatgaaatggagcagaaatgcagaacttcaaacttaaaacta
gacaagataatgaaagaattggatgaagaggggaatcaaagaagaaatctagaatctgca
gtgtctcaaattgagaaagaaaagatgttgctacaacatagaattaatgagtaccaaaga
aaagtggaacaggaaaatgagaagagaagaaatatagaaaatgaagtttctacactaaag
gaccagttagaagacttacggaaagcaagtcagacctcacagcttgctaatgagaagctg
acacagttacagaagcagttagaagaagcgaatgacttacttaggacagaatcagacaca
gctgtaagattaaggaagagtcacacagagatgagcaagtcaattagtcagctagagtcc
ctgaacagagaattacaggaaagaaacagaattttagagaattccaagtcacaagcagac
aaggattactaccagctgcaagctgtattggaagctgagcgaagagacagagggcatgat
tctgagatgattggagaccttcaagcacgaattacatctttacaagaagaagtgaaacat
ctcaaacataatcttgaaagagtggaaggagaaagaaaagaggctcaagacatgcttaat
cattcagaaaaggaaaagaataatttggagatagatttgaattacaagctcaagtctata
caacagcggttagaacaagaagtaaatgaacataaagtcaccaaagcacgcctaactgac
aagcaccaatctatcgaagaggcaaagtctgttgccatgtgtgaaatggaaaaaaagctg
aaggaagagagagaagctcgagagaaggcagaaaatagagttgttgagactgagaaacaa
tgttccatgctagatgttgacctgaaacagtctcagcagaagctagaacatttgaccgaa
aataaagaaaggatggaggatgaagttaagaatctcgccctgcagctggaacaggaatca
aataaacggctcttgttacagaatgaattgaagactcaagcatttgaagcagacaattta
aaaggtttagaaaaacagatgaaacaggaaataaatactttattggaagcaaagagattg
ttagaatttgagttagctcagcttacaaagcaatataggggaaatgaagggcaaatgcgg
gagttacaagatcaacttgaagctgagcagtatttctctacactttataaaacccaagta
aaggagcttaaagaagaaattgaagaaaaaaaccgagaaaatttaaggaaaatacaggaa
ctgcaaagtgaaaaagaaactctctctactcagttggatttagcagaaacaaaagctgag
tctgagcagctggcgcgagggattctggaagaacagtattttgagttgactcaggaaagc
aagaaagctgcttcaagaaatagacaagagattacagataaagatcatactgttagtcgg
cttgaagaaacaaacagtgtgctaaccaaagatattgaaatgctaagaaaagaaaatgaa
gagctaaatgaaagaatgaggacagcagaagaagaatataaattgaagaaggaggaagaa
ataaataatcttaaggctgcttttgaaaagaatatcagtaccgaacggacccttaaaaca
caggctgttaacaagttggcagaaataatgaatcgcaaagattttaaaattgatcgaaag
aaagctaatacacaagatttaagaaaaaaagaaaaggaaaatagaaagctacaactggaa
cttaaccaagagagagaaaaatttaaccaaatggtggtgaaacaccagaaggagctgaat
gacatgcaagcgcaattggtagaagaatgtacacatagaaatgaacttcaaatgcagttg
gctagcaaagagagtgatattgagcagttgcgggcaaaacttttggacctttcggattca
actagtgttgctagttttcctagtgcagatgaaactgatggaaaccttccagagtcaaga
attgaaggttggctttctgtaccaaatagaggaaatatcaaaagatatggctggaagaaa
cagtatgttgtggtaagcagcaaaaagatcttgttctataatgatgaacaagataaggaa
caatccagtccatctatggtgttagacatagataaattgtttcatgtccgacctgtaacc
caaggagatgtgtacagagcagaaactgaagaaattcctaaaatattccagatactatat
gcaaatgaaggtgaatgtagaaaagatatagaagtggaaccggttcaacaaggtgaaaaa
actaatttccagaatcacaaaggccatgaattcattcctaccctctaccactttcctgcc
aactgtgaggcctgtgccaaacctttgtggcatgtctttaagccaccacctgccctagag
tgtcgaagatgccatgttaagtgccacagagaccatctagacaagaaagaggacttgatt
tccccgtgcaaagtaagttacgatgtaacatcagcaagagatatgctgctgttagcatgt
tctcaggatgaacaaaaaaagtgggttactcatctagtaaagaagattcctaagaaccca
ccatctggctttgtccgtgcctctcctcgaacgctgtcaacaagatccactgcaaatcag
tctttccgcaaagtagtcaaaaatacatctggaaaaactagttaa
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integrated database retrieval system
