Mus musculus (house mouse): 20662
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Entry
20662 CDS
T01002
Symbol
Sos1, 4430401P03Rik, 9630010N06
Name
(RefSeq) SOS Ras/Rac guanine nucleotide exchange factor 1
KO
K03099
son of sevenless
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01521
EGFR tyrosine kinase inhibitor resistance
mmu01522
Endocrine resistance
mmu04010
MAPK signaling pathway
mmu04012
ErbB signaling pathway
mmu04014
Ras signaling pathway
mmu04062
Chemokine signaling pathway
mmu04068
FoxO signaling pathway
mmu04072
Phospholipase D signaling pathway
mmu04150
mTOR signaling pathway
mmu04151
PI3K-Akt signaling pathway
mmu04510
Focal adhesion
mmu04540
Gap junction
mmu04630
JAK-STAT signaling pathway
mmu04650
Natural killer cell mediated cytotoxicity
mmu04660
T cell receptor signaling pathway
mmu04662
B cell receptor signaling pathway
mmu04664
Fc epsilon RI signaling pathway
mmu04714
Thermogenesis
mmu04722
Neurotrophin signaling pathway
mmu04810
Regulation of actin cytoskeleton
mmu04910
Insulin signaling pathway
mmu04912
GnRH signaling pathway
mmu04915
Estrogen signaling pathway
mmu04917
Prolactin signaling pathway
mmu04926
Relaxin signaling pathway
mmu04935
Growth hormone synthesis, secretion and action
mmu05034
Alcoholism
mmu05160
Hepatitis C
mmu05161
Hepatitis B
mmu05163
Human cytomegalovirus infection
mmu05165
Human papillomavirus infection
mmu05200
Pathways in cancer
mmu05205
Proteoglycans in cancer
mmu05206
MicroRNAs in cancer
mmu05207
Chemical carcinogenesis - receptor activation
mmu05208
Chemical carcinogenesis - reactive oxygen species
mmu05210
Colorectal cancer
mmu05211
Renal cell carcinoma
mmu05213
Endometrial cancer
mmu05214
Glioma
mmu05215
Prostate cancer
mmu05220
Chronic myeloid leukemia
mmu05221
Acute myeloid leukemia
mmu05223
Non-small cell lung cancer
mmu05224
Breast cancer
mmu05225
Hepatocellular carcinoma
mmu05226
Gastric cancer
mmu05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
20662 (Sos1)
04630 JAK-STAT signaling pathway
20662 (Sos1)
04068 FoxO signaling pathway
20662 (Sos1)
04072 Phospholipase D signaling pathway
20662 (Sos1)
04151 PI3K-Akt signaling pathway
20662 (Sos1)
04150 mTOR signaling pathway
20662 (Sos1)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
20662 (Sos1)
04660 T cell receptor signaling pathway
20662 (Sos1)
04662 B cell receptor signaling pathway
20662 (Sos1)
04664 Fc epsilon RI signaling pathway
20662 (Sos1)
04062 Chemokine signaling pathway
20662 (Sos1)
09152 Endocrine system
04915 Estrogen signaling pathway
20662 (Sos1)
04917 Prolactin signaling pathway
20662 (Sos1)
04926 Relaxin signaling pathway
20662 (Sos1)
04935 Growth hormone synthesis, secretion and action
20662 (Sos1)
09156 Nervous system
04722 Neurotrophin signaling pathway
20662 (Sos1)
09159 Environmental adaptation
04714 Thermogenesis
20662 (Sos1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
20662 (Sos1)
05206 MicroRNAs in cancer
20662 (Sos1)
05205 Proteoglycans in cancer
20662 (Sos1)
05207 Chemical carcinogenesis - receptor activation
20662 (Sos1)
05208 Chemical carcinogenesis - reactive oxygen species
20662 (Sos1)
05231 Choline metabolism in cancer
20662 (Sos1)
09162 Cancer: specific types
05210 Colorectal cancer
20662 (Sos1)
05225 Hepatocellular carcinoma
20662 (Sos1)
05226 Gastric cancer
20662 (Sos1)
05214 Glioma
20662 (Sos1)
05221 Acute myeloid leukemia
20662 (Sos1)
05220 Chronic myeloid leukemia
20662 (Sos1)
05211 Renal cell carcinoma
20662 (Sos1)
05215 Prostate cancer
20662 (Sos1)
05213 Endometrial cancer
20662 (Sos1)
05224 Breast cancer
20662 (Sos1)
05223 Non-small cell lung cancer
20662 (Sos1)
09172 Infectious disease: viral
05161 Hepatitis B
20662 (Sos1)
05160 Hepatitis C
20662 (Sos1)
05163 Human cytomegalovirus infection
20662 (Sos1)
05165 Human papillomavirus infection
20662 (Sos1)
09165 Substance dependence
05034 Alcoholism
20662 (Sos1)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
20662 (Sos1)
01522 Endocrine resistance
20662 (Sos1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
RasGEF
RasGEF_N
RhoGEF
SOS1_NGEF_PH
PH
PH_19
PH_10
IQ_SEC7_PH
RHG20_PH
DUF6018
Takusan
Motif
Other DBs
NCBI-GeneID:
20662
NCBI-ProteinID:
NP_033257
MGI:
98354
Ensembl:
ENSMUSG00000024241
UniProt:
Q62245
Q3USK4
Structure
PDB
PDBj
LinkDB
All DBs
Position
17:complement(80701181..80787882)
Genome browser
AA seq
1319 aa
AA seq
DB search
MQAQQLPYEFFSEENAPKWRGLLVPALKKVQGQVHPTLESNDDALQYVEELILQLLNMLC
QAQPRSASDVEERVQKSFPHPIDKWAIADAQSAIEKRKRRNPLSLPAERIHHLLREVLGY
KIDHQVSVYIVAVLEYISADILKLVGNYVRNIRHYEITKQDIKVAMCADKVLMDMFHQDV
EDINILSLTDEEPSTSGEQTYYDLVKAFMAEIRQYIRELNLIIKVFREPFVSNSKLFSSN
DVENIFSRIVDIHELSVKLLGHIEDTVEMTDEGSPHPLVGSCFEDLAEELAFDPYESYAR
DILRPGFHGHFLSQLSKPGAALYLQSIGEGFKEAVQYVLPRLLLAPVYHCLHYFELLKQL
EEKSEDQEDKECMKQAITALLNVQSGMEKICSKSLAKRRLSESACRFYSQQMKGKQLAIK
KMNEIQKNIDGWEGKDIGQCCNEFIMEGTLTRVGAKHERHIFLFDGLMICCKSNHGQPRL
PGASSAEYRLKEKFFMRKVQINDKDDTSEYKHAFEIILKDGNSVIFSAKSAEEKNNWMAA
LISLQYRSTLERMLDVTVLQEEKEEQMRLPSAEVYRFAEPDSEENILFEENVQPKAGIPI
IKAGTVLKLIERLTYHMYADPNFVRTFLTTYRSFCRPQELLSLLIERFEIPEPEPTEADR
IAIENGDQPLSAELKRFRKEYIQPVQLRVLNVCRHWVEHHFYDFERDADLLQRMEEFIGT
VRGKAMKKWVESITKIIQRKKIARDNGPGHNITFQSSPPTVEWHISRPGHIETFDLLTLH
PIEIARQLTLLESDLYRAVQPSELVGSVWTKEDKEINSPNLLKMIRHTTNLTLWFEKCIV
ETENLEERVAVVSRIIEILQVFQELNNFNGVLEVVSAMNSSPVYRLDHTFEQIPSRQKKI
LEEAHELSEDHYKKYLAKLRSINPPCVPFFGIYLTNILKTEEGNPEVLRRHGKELINFSK
RRRVAEITGEIQQYQNQPYCLRVEPDIKRFFENLNPMGNSMEKEFTDYLFNKSLEIEPRH
PKPLPRFPKKYSYPLKSPGVRPSNPRPGTMRHPTPLQQEPRKISYSRIPESETESTASAP
NSPRTPLTPPPASGTSSNTDVCSVFDSDHSASPFHSRSASVSSISLSKGTDEVPVPPPVP
PRRRPESAPAESSPSKIMSKHLDSPPAIPPRQPTSKAYSPRYSISDRTSISDPPESPPLL
PPREPVRTPDVFSSSPLHLQPPPLGKKSDHGNAFFPNSPSPFTPPPPQTPSPHGTRRHLP
SPPLTQEMDLHSIAGPPVPPRQSTSQLIPKLPPKTYKREHTHPSMHRDGPPLLENAHSS
NT seq
3960 nt
NT seq
+upstream
nt +downstream
nt
atgcaggcgcagcagctgccttacgagtttttcagcgaggagaacgcgcccaagtggcgg
gggctgctggtgcctgcgctgaaaaaggttcaggggcaagttcaccctactcttgagtct
aatgatgatgctcttcagtatgttgaagaattaattttgcaattactaaatatgctatgc
caagctcagccccggagtgcttcagatgtggaggaacgtgttcaaaagagttttcctcat
ccaattgataagtgggcaatagctgatgcccaatcagccattgaaaagaggaagagacga
aatcctttatcgctgccagcagaaagaattcatcatttattaagggaggtcctcggttat
aaaattgaccaccaggtttctgtttacatagtagcagtattagaatacatttctgcagat
attttaaagctcgtggggaattatgtaagaaatatacggcattatgaaattacaaaacaa
gacattaaagtggcaatgtgtgctgataaggtattgatggatatgtttcatcaagatgta
gaagatataaatatcttatctttaactgatgaagagccttccacctcaggagaacaaact
tattatgatttggtaaaagcattcatggcagaaattcgacagtatataagagaattaaat
ctaattataaaagtttttcgagagccctttgtctctaattccaaattgttttcatctaat
gatgtagaaaacatattcagtcgtatagtagatatacatgaacttagtgtaaagttactg
ggccatatagaagatactgtagaaatgacagatgaaggcagtccccacccattagtagga
agctgttttgaagacttagcagaagaactggcatttgacccgtatgagtcatatgctcgg
gatattttacgacccggattccatggccattttcttagtcagttatcaaagcctggggca
gcactttatttgcagtccataggcgaaggcttcaaagaagctgtccagtacgtcctgccc
cggctgctgcttgcccctgtgtaccactgtctgcattactttgaacttctgaagcagtta
gaagaaaagagtgaagatcaagaagacaaggagtgtatgaagcaagcaataacagccctg
cttaatgtccaaagtggcatggaaaaaatttgctccaaaagtcttgcaaaacgaagacta
agtgagtctgcatgtcggttttacagccagcagatgaaggggaaacagctagccatcaag
aagatgaacgagatccagaagaacattgatggctgggaggggaaggacattggacagtgt
tgcaatgagttcataatggaaggaactcttacacgtgtaggagccaaacacgagagacac
atatttctcttcgatggcttaatgatttgctgtaaatcaaaccatgggcagccaagactc
cctggtgctagcagtgcagaataccggcttaaagaaaagttttttatgcgaaaggtacag
attaatgataaagatgacaccagtgagtacaagcatgcttttgaaatcattctgaaagat
ggcaatagtgttatattttctgccaagtcagctgaagagaaaaacaactggatggcagca
ctgatctctttgcagtaccgcagcaccctggagaggatgctggacgtaacggtgctgcag
gaggagaaggaggagcagatgaggctgcccagtgctgaagtgtacaggtttgcagaacct
gactccgaggagaatattctattcgaagagaatgtgcagcccaaagctgggatccccatt
atcaaggcagggacagtgcttaagctcattgagaggcttacctaccacatgtacgcagat
ccaaattttgttcggacgtttcttacaacatacaggtccttttgcagacctcaagaacta
ctgagtcttctgatagaaagatttgaaattccagagcctgagccaacagaagctgatcgc
atagctatagagaatggagatcagcccctgagtgcagagctgaagaggtttagaaaggaa
tatattcagcctgtgcagttgagggtgttaaatgtgtgtcggcactgggtggagcaccat
ttctatgactttgaaagagatgcagaccttttacagagaatggaggaatttattggaaca
gtaagaggtaaagcaatgaaaaaatgggtcgaatccatcactaagataatccaaaggaaa
aaaattgcaagagacaatggcccaggtcataacattacatttcagagctcacctcccaca
gttgagtggcacataagcagacctgggcacatagagacttttgacttgctcaccttacac
ccaatagaaattgctcggcaactcactttacttgaatcagatctataccgggctgtgcag
ccatcagaattagttggaagtgtgtggacaaaagaagataaagaaattaattctcccaac
cttctgaagatgattcggcacaccactaacctcactttgtggtttgagaaatgtattgta
gaaacagaaaacttagaagaaagagtagctgtagtaagtcggataattgagattctacaa
gtctttcaagagctgaacaacttcaatggtgtcctggaagttgtcagtgctatgaactcg
tcacctgtttacagactagaccacacatttgagcaaataccaagcagacaaaagaaaatt
ttagaagaagctcatgaattgagtgaagatcactataagaaatatttggcaaaactcagg
tctattaatccaccgtgtgtgcctttctttggaatttatctcacaaatatcctgaagaca
gaagagggcaaccctgaggtcctgaggagacacgggaaagagcttattaacttcagcaag
aggaggagagtggccgagatcacaggcgagatccagcagtaccagaaccagccctactgc
ttacgggtggagccggacatcaagaggttctttgaaaacttgaatccaatgggaaacagc
atggagaaagaatttacagactatctgttcaacaaatccctagaaatagaaccccggcac
cctaagcctcttccgagattcccaaaaaaatacagctatcccctaaaatctcctggtgtt
cgtccatcaaatccaagaccaggaaccatgagacatcccacacctctgcagcaggagcca
agaaaaattagctacagtcggattcctgaaagtgagacggaaagcacagcatctgcacca
aactcccctcggaccccactgacgccgccccctgcatctggcacctccagcaacacagat
gtttgcagcgtgttcgattctgaccactcggcaagcccttttcattcaagatctgcttca
gtctcatctataagtttatccaagggcactgatgaagtgcctgtcccccctcctgtaccc
cctcgaagacgtccagagtctgccccagctgaatcctccccatccaagattatgtctaag
cacttggacagccccccagctattcctcctaggcaacccacatccaaagcctattcacca
cgctattcaatatcagatcggacctctatatcagatcctcctgaaagccctcccttgtta
ccaccacgggaacctgtgaggacacctgatgttttctcaagctcaccattacatctccaa
cctcctcctttgggcaaaaagagtgatcatggcaacgccttcttcccaaacagcccatcc
ccttttacaccgccacccccccaaaccccctctcctcatggcacgagaaggcatctgcca
tcaccaccactgacacaggagatggacctccattccattgctgggcctcctgttcctcca
cgacaaagcacttctcaacttatccccaaactccctccaaaaacttacaaaagggagcac
acacacccatccatgcatagagatggaccaccactgctggagaatgcccattcttcctga
DBGET
integrated database retrieval system
