Mus musculus (house mouse): 20779
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Entry
20779 CDS
T01002
Symbol
Src, pp60c-src
Name
(RefSeq) Rous sarcoma oncogene
KO
K05704
tyrosine-protein kinase Src [EC:
2.7.10.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01521
EGFR tyrosine kinase inhibitor resistance
mmu01522
Endocrine resistance
mmu04012
ErbB signaling pathway
mmu04015
Rap1 signaling pathway
mmu04062
Chemokine signaling pathway
mmu04137
Mitophagy - animal
mmu04144
Endocytosis
mmu04360
Axon guidance
mmu04370
VEGF signaling pathway
mmu04510
Focal adhesion
mmu04520
Adherens junction
mmu04530
Tight junction
mmu04540
Gap junction
mmu04611
Platelet activation
mmu04613
Neutrophil extracellular trap formation
mmu04625
C-type lectin receptor signaling pathway
mmu04727
GABAergic synapse
mmu04750
Inflammatory mediator regulation of TRP channels
mmu04810
Regulation of actin cytoskeleton
mmu04912
GnRH signaling pathway
mmu04915
Estrogen signaling pathway
mmu04917
Prolactin signaling pathway
mmu04919
Thyroid hormone signaling pathway
mmu04921
Oxytocin signaling pathway
mmu04926
Relaxin signaling pathway
mmu05100
Bacterial invasion of epithelial cells
mmu05135
Yersinia infection
mmu05152
Tuberculosis
mmu05161
Hepatitis B
mmu05163
Human cytomegalovirus infection
mmu05167
Kaposi sarcoma-associated herpesvirus infection
mmu05168
Herpes simplex virus 1 infection
mmu05203
Viral carcinogenesis
mmu05205
Proteoglycans in cancer
mmu05207
Chemical carcinogenesis - receptor activation
mmu05208
Chemical carcinogenesis - reactive oxygen species
mmu05219
Bladder cancer
mmu05417
Lipid and atherosclerosis
mmu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
20779 (Src)
04015 Rap1 signaling pathway
20779 (Src)
04370 VEGF signaling pathway
20779 (Src)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
20779 (Src)
04137 Mitophagy - animal
20779 (Src)
09144 Cellular community - eukaryotes
04510 Focal adhesion
20779 (Src)
04520 Adherens junction
20779 (Src)
04530 Tight junction
20779 (Src)
04540 Gap junction
20779 (Src)
09142 Cell motility
04810 Regulation of actin cytoskeleton
20779 (Src)
09150 Organismal Systems
09151 Immune system
04611 Platelet activation
20779 (Src)
04613 Neutrophil extracellular trap formation
20779 (Src)
04625 C-type lectin receptor signaling pathway
20779 (Src)
04062 Chemokine signaling pathway
20779 (Src)
09152 Endocrine system
04912 GnRH signaling pathway
20779 (Src)
04915 Estrogen signaling pathway
20779 (Src)
04917 Prolactin signaling pathway
20779 (Src)
04921 Oxytocin signaling pathway
20779 (Src)
04926 Relaxin signaling pathway
20779 (Src)
04919 Thyroid hormone signaling pathway
20779 (Src)
09156 Nervous system
04727 GABAergic synapse
20779 (Src)
09157 Sensory system
04750 Inflammatory mediator regulation of TRP channels
20779 (Src)
09158 Development and regeneration
04360 Axon guidance
20779 (Src)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
20779 (Src)
05207 Chemical carcinogenesis - receptor activation
20779 (Src)
05208 Chemical carcinogenesis - reactive oxygen species
20779 (Src)
05203 Viral carcinogenesis
20779 (Src)
09162 Cancer: specific types
05219 Bladder cancer
20779 (Src)
09172 Infectious disease: viral
05161 Hepatitis B
20779 (Src)
05168 Herpes simplex virus 1 infection
20779 (Src)
05163 Human cytomegalovirus infection
20779 (Src)
05167 Kaposi sarcoma-associated herpesvirus infection
20779 (Src)
09171 Infectious disease: bacterial
05135 Yersinia infection
20779 (Src)
05152 Tuberculosis
20779 (Src)
05100 Bacterial invasion of epithelial cells
20779 (Src)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
20779 (Src)
05418 Fluid shear stress and atherosclerosis
20779 (Src)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
20779 (Src)
01522 Endocrine resistance
20779 (Src)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
20779 (Src)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
mmu04131
]
20779 (Src)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
20779 (Src)
Protein kinases [BR:
mmu01001
]
Non-receptor tyrosine kinases
SRC family
20779 (Src)
Membrane trafficking [BR:
mmu04131
]
Exocytosis
Calcium ion-dependent exocytosis
Kinases and associated proteins
20779 (Src)
Endocytosis
Clathrin-mediated endocytosis
Kinases
20779 (Src)
Lipid raft mediated endocytosis
Caveolin-mediated endocytosis
20779 (Src)
Macropinocytosis
Kinases
20779 (Src)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_9
SH3_2
SH2_1
SH3_10
ABC1
Haspin_kinase
SH3_3
Motif
Other DBs
NCBI-GeneID:
20779
NCBI-ProteinID:
NP_001020566
MGI:
98397
Ensembl:
ENSMUSG00000027646
UniProt:
P05480
Structure
PDB
PDBj
LinkDB
All DBs
Position
2:157265828..157313758
Genome browser
AA seq
535 aa
AA seq
DB search
MGSNKSKPKDASQRRRSLEPSENVHGAGGAFPASQTPSKPASADGHRGPSAAFVPPAAEP
KLFGGFNSSDTVTSPQRAGPLAGGVTTFVALYDYESRTETDLSFKKGERLQIVNNTEGDW
WLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESE
TTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLC
HRLTTVCPTSKPQTQGLAKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLK
PGTMSPEAFLQEAQVMKKLRHEKLVQLYAVVSEEPIYIVTEYMNKGSLLDFLKGETGKYL
RLPQLVDMSAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIEDNEYTA
RQGAKFPIKWTAPEAALYGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERG
YRMPCPPECPESLHDLMCQCWRKEPEERPTFEYLQAFLEDYFTSTEPQYQPGENL
NT seq
1608 nt
NT seq
+upstream
nt +downstream
nt
atgggcagcaacaagagcaagcccaaggacgccagccagcggcgccgcagcctggagccc
tcggaaaacgtgcacggggcagggggcgccttcccggcctcacagacaccgagcaagccc
gcctccgccgacggccaccgcgggcccagcgccgccttcgtgccgcccgcggccgagccc
aagctcttcggaggcttcaactcctcggacaccgtcacctccccgcagagggcggggcct
ctggcaggtggggtgaccacctttgtggccctctatgactatgagtcacggacagagact
gacctgtccttcaagaaaggggagcggctgcagattgtcaataacacagagggagactgg
tggctggcacactcgctgagcacgggacagaccggttacatccccagcaactatgtggcg
ccctccgactccatccaggctgaggagtggtactttggcaagatcactagacgggaatca
gagcggctgctgctcaacgccgagaacccgagagggaccttcctcgtgagggagagtgag
accacaaaaggtgcctactgcctctctgtatccgacttcgacaatgccaagggcctaaat
gtgaaacactacaagatccgcaagctggacagcggcggtttctacatcacctcccgcacc
cagttcaacagcctgcagcagctcgtggcttactactccaaacatgctgatggcctgtgt
caccgcctcactaccgtatgtcccacatccaagcctcagacccagggattggccaaggat
gcgtgggagatcccccgggagtccctgcggctggaggtcaagctgggccagggttgcttc
ggagaggtgtggatggggacctggaacggcaccacgagggttgccatcaaaactctgaag
ccaggcaccatgtccccagaggccttcctgcaggaggcccaagtcatgaagaaactgagg
cacgagaaactggtgcagctgtatgctgtggtgtcggaagaacccatttacattgtgaca
gagtacatgaacaaggggagtctgctggactttctcaagggggaaacgggcaaatatttg
cggctaccccagctggtggacatgtctgctcagatcgcttcaggcatggcctatgtggag
cggatgaactatgtgcaccgggaccttcgagccgccaatatcctagtaggggagaacctg
gtgtgcaaagtggccgactttgggttggcccggctcatagaagacaacgaatacacagcc
cggcaaggtgccaaattccccatcaagtggaccgcccctgaagctgctctgtacggcagg
ttcaccatcaagtcggatgtgtggtcctttgggattctgctgaccgagctcaccactaag
ggaagagtgccctatcctgggatggtgaaccgtgaggttctggaccaggtggagcggggc
taccggatgccttgtccccccgagtgccccgagtccctgcatgaccttatgtgccagtgc
tggcggaaggagcccgaggagcggcccaccttcgagtacctgcaggccttcctggaagac
tactttacgtccactgagccacagtaccagcccggggagaacctatag
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