Mus musculus (house mouse): 216456
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Entry
216456 CDS
T01002
Symbol
Gls2, A330074B06Rik, GA, GLS, Lga
Name
(RefSeq) glutaminase 2 (liver, mitochondrial)
KO
K01425
glutaminase [EC:
3.5.1.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu00220
Arginine biosynthesis
mmu00250
Alanine, aspartate and glutamate metabolism
mmu00470
D-Amino acid metabolism
mmu01100
Metabolic pathways
mmu04724
Glutamatergic synapse
mmu04727
GABAergic synapse
mmu04964
Proximal tubule bicarbonate reclamation
mmu05206
MicroRNAs in cancer
mmu05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09100 Metabolism
09105 Amino acid metabolism
00250 Alanine, aspartate and glutamate metabolism
216456 (Gls2)
00220 Arginine biosynthesis
216456 (Gls2)
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
216456 (Gls2)
09150 Organismal Systems
09155 Excretory system
04964 Proximal tubule bicarbonate reclamation
216456 (Gls2)
09156 Nervous system
04724 Glutamatergic synapse
216456 (Gls2)
04727 GABAergic synapse
216456 (Gls2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
216456 (Gls2)
05230 Central carbon metabolism in cancer
216456 (Gls2)
Enzymes [BR:
mmu01000
]
3. Hydrolases
3.5 Acting on carbon-nitrogen bonds, other than peptide bonds
3.5.1 In linear amides
3.5.1.2 glutaminase
216456 (Gls2)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Glutaminase
EF-hand_14
Ank_4
Ank_2
Ank
Ank_5
Ank_3
Motif
Other DBs
NCBI-GeneID:
216456
NCBI-ProteinID:
NP_001028436
MGI:
2143539
Ensembl:
ENSMUSG00000044005
UniProt:
Q571F8
LinkDB
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Position
10:128030504..128045873
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AA seq
602 aa
AA seq
DB search
MRSMRALQNALSRAGSHGRRGGWGHPSRGPLLGRGVRYYLGEAAAQGRGTPHSHQPQHSD
HDASHSGMLPRLGDLLFYTIAEGQERIPIHKFTTALKATGLQTSDPRLQDCMSKMQRMVQ
ESSSGGLLDRELFQKCVSSNIVLLTQAFRKKFVIPDFEEFTGHVDRIFEDAKEPTGGKVA
AYIPHLAKSNPDLWGVSLCTVDGQRHSVGHTKIPFCLQSCVKPLTYAISVSTLGTDYVHK
FVGKEPSGLRYNKLSLNEEGIPHNPMVNAGAIVVSSLIKMDCNKAEKFDFVLQYLNKMAG
NEFMGFSNATFQSEKETGDRNYAIGYYLKEKKCFPKGVDMMAALDLYFQLCSVEVTCESG
SVMAATLANGGICPITGESVLSAEAVRNTLSLMHSCGMYDFSGQFAFHVGLPAKSAVSGA
ILLVVPNVMGMMCLSPPLDKLGNSQRGINFCQKLVSLFNFHNYDNLRHCARKLDPRREGG
EVRNKTVVNLLFAAYSGDVSALRRFALSAMDMEQKDYDSRTALHVAAAEGHIEVVKFLIE
ACKVNPFVKDRWGNIPLDDAVQFNHLEVVKLLQDYHDSYLLSETQAEAAAETLSKENLES
MV
NT seq
1809 nt
NT seq
+upstream
nt +downstream
nt
atgcgctccatgagggctctgcagaacgcgctgagccgcgcgggcagccacggtcggcgg
ggaggctggggtcatccgagccggggcccgcttctgggcaggggcgtccggtactacctc
ggtgaggccgcagcgcagggcagggggacgccgcacagccaccagccgcagcactcggat
catgacgcctcacacagcggcatgctgcctcgacttggtgacctgcttttctacactatt
gcagagggacaggagcgtatccctatccacaagttcaccacggctctgaaggccactgga
ctgcagacgtcagacccacggctccaggactgcatgagcaagatgcagcgcatggtccaa
gagtccagcagcggtggcctcttggaccgagagctcttccaaaagtgtgtgagcagcaac
attgtgctcctgactcaggcattccgaaagaagtttgtcattcctgactttgaggagttc
acgggccatgtggatcgcatatttgaggatgccaaagagcccactggaggcaaagtggca
gcctacatcccgcacctggccaaatcaaacccagacctttggggcgtctccctgtgcact
gtggatgggcagcggcactctgtgggccacacgaagatccccttctgcctgcagtcctgt
gtcaagcccctcacttacgccatctccgtgagcaccttaggcactgactacgtgcacaag
tttgtgggcaaggaacccagtggtctgcgctataacaaactctccctcaatgaggaagga
attccccataaccccatggtcaatgctggtgccattgtggtcagctccctgatcaagatg
gactgtaacaaagcagagaagttcgattttgtgttacagtatctgaacaagatggctggg
aacgaattcatggggttcagcaatgccacattccagtcagagaaggagactggggatcgg
aattacgccatcggctattacctcaaggagaagaagtgcttccctaagggtgtggacatg
atggctgcccttgatctctatttccagctgtgctctgtggaggttacctgtgagtcaggc
agtgtcatggcggccactctggccaatggcggcatctgccctatcacaggggagagcgtg
ctgagcgccgaggccgtgcgcaacaccctcagcctcatgcattcctgtggcatgtatgac
ttctcgggccagtttgccttccatgtgggcctgccagccaagtcagctgtgtcaggagcc
atcctcctggttgtacccaatgtcatgggcatgatgtgtctgtcgccgccgttagacaag
ctggggaacagccaaaggggcatcaacttctgccagaagttggtgtctctctttaacttc
cacaactatgacaacctgcggcactgcgctcggaagttagacccacggagggaaggagga
gaggttcggaacaagaccgtggtgaacctgctatttgctgcatatagtggagatgtctcg
gcccttcgaaggtttgcattgtcggccatggatatggagcagaaggactatgattcccgc
acagccctacatgtcgctgcagctgaagggcacattgaagttgtcaaatttctgatcgag
gcttgcaaagtgaatccttttgtcaaggacaggtggggcaacattcccctggacgatgct
gtgcagttcaaccacctggaggtggtcaaactgcttcaagattaccatgactcctacttg
ctctctgagactcaagctgaggcggcagctgagaccctgtccaaagagaatctagagagc
atggtatga
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