Mus musculus (house mouse): 21687 Help Entry 21687             CDS       T01002                                  Symbol Tek, Cd202b, Hyk, STK1, Tie-2, Tie2 Name (RefSeq) TEK receptor tyrosine kinase   KO K05121   endothelial-specific receptor tyrosine kinase [EC:2.7.10.1] Organism mmu  Mus musculus (house mouse) Pathway mmu04010   MAPK signaling pathway mmu04014   Ras signaling pathway mmu04015   Rap1 signaling pathway mmu04066   HIF-1 signaling pathway mmu04151   PI3K-Akt signaling pathway mmu05323   Rheumatoid arthritis Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     21687 (Tek)    04014 Ras signaling pathway     21687 (Tek)    04015 Rap1 signaling pathway     21687 (Tek)    04066 HIF-1 signaling pathway     21687 (Tek)    04151 PI3K-Akt signaling pathway     21687 (Tek)  09160 Human Diseases   09163 Immune disease    05323 Rheumatoid arthritis     21687 (Tek)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:mmu01001]     21687 (Tek)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:mmu04090]     21687 (Tek) Enzymes [BR:mmu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      21687 (Tek) Protein kinases [BR:mmu01001]  Receptor tyrosine kinases (RTK)   TIE family    21687 (Tek) CD molecules [BR:mmu04090]  Proteins   21687 (Tek) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Ig_Tie2_1 Pkinase fn3 Pur_ac_phosph_N Ig_DSCAM-DSCAML_C EGF_2 EGF_TEN hEGF ig NDNF EGF_laminin EGF_Teneurin I-set GH101_dom-5 APH Haspin_kinase DUF4702 Motif Other DBs NCBI-GeneID:  21687 NCBI-ProteinID:  NP_001277478 MGI:  98664 Ensembl:  ENSMUSG00000006386 UniProt:  Q02858 LinkDB All DBs Position 4:94627322..94763213 Genome browser AA seq 1122 aa AA seqDB search MDSLAGLVLCGVSLLLYGVVEGAMDLILINSLPLVSDAETSLTCIASGWHPHEPITIGRD FEALMNQHQDPLEVTQDVTREWAKKVVWKREKASKINGAYFCEGRVRGQAIRIRTMKMRQ QASFLPATLTMTVDRGDNVNISFKKVLIKEEDAVIYKNGSFIHSVPRHEVPDILEVHLPH AQPQDAGVYSARYIGGNLFTSAFTRLIVRRCEAQKWGPDCSRPCTTCKNNGVCHEDTGEC ICPPGFMGRTCEKACEPHTFGRTCKERCSGPEGCKSYVFCLPDPYGCSCATGWRGLQCNE ACPSGYYGPDCKLRCHCTNEEICDRFQGCLCSQGWQGLQCEKEGRPRMTPQIEDLPDHIE VNSGKFNPICKASGWPLPTSEEMTLVKPDGTVLQPNDFNYTDRFSVAIFTVNRVLPPDSG VWVCSVNTVAGMVEKPFNISVKVLPEPLHAPNVIDTGHNFAIINISSEPYFGDGPIKSKK LFYKPVNQAWKYIEVTNEIFTLNYLEPRTDYELCVQLARPGEGGEGHPGPVRRFTTASIG LPPPRGLSLLPKSQTALNLTWQPIFTNSEDEFYVEVERRSLQTTSDQQNIKVPGNLTSVL LSNLVPREQYTVRARVNTKAQGEWSEELRAWTLSDILPPQPENIKISNITDSTAMVSWTI VDGYSISSIIIRYKVQGKNEDQHIDVKIKNATVTQYQLKGLEPETTYHVDIFAENNIGSS NPAFSHELRTLPHSPASADLGGGKMLLIAILGSAGMTCITVLLAFLIMLQLKRANVQRRM AQAFQNREEPAVQFNSGTLALNRKAKNNPDPTIYPVLDWNDIKFQDVIGEGNFGQVLKAR IKKDGLRMDAAIKRMKEYASKDDHRDFAGELEVLCKLGHHPNIINLLGACEHRGYLYLAI EYAPHGNLLDFLRKSRVLETDPAFAIANSTASTLSSQQLLHFAADVARGMDYLSQKQFIH RDLAARNILVGENYIAKIADFGLSRGQEVYVKKTMGRLPVRWMAIESLNYSVYTTNSDVW SYGVLLWEIVSLGGTPYCGMTCAELYEKLPQGYRLEKPLNCDDEVYDLMRQCWREKPYER PSFAQILVSLNRMLEERKTYVNTTLYEKFTYAGIDCSAEEAA NT seq 3369 nt NT seq  +upstreamnt  +downstreamnt atggactctttagccggcttagttctctgtggagtcagcttgctcctttatggagtagta gaaggcgccatggacctgatcttgatcaattccctacctcttgtgtctgatgccgaaaca tccctcacctgcattgcctctgggtggcacccccatgagcccatcaccataggaagggac tttgaagccttaatgaaccagcaccaagatccactggaggttactcaagatgtgaccaga gaatgggcgaaaaaagttgtttggaagagagaaaaggccagtaagattaatggtgcttat ttctgtgaaggtcgagttcgaggacaggctataaggatacggaccatgaagatgcgtcaa caagcatccttcctacctgctactttaactatgaccgtggacaggggagataatgtgaac atatctttcaaaaaggtgttaattaaagaagaagatgcagtgatttacaaaaatggctcc ttcatccactcagtgccccggcatgaagtacctgatattttagaagttcacttgccgcat gctcagccccaggatgctggtgtgtactcggccaggtacataggaggaaacctgttcacc tcagccttcaccaggctgattgttcggagatgtgaagctcagaagtgggggcccgactgt agccgtccttgtactacttgcaagaacaatggagtctgccatgaagataccggggaatgc atttgccctcctgggtttatggggagaacatgtgagaaagcttgtgagccgcacacattt ggcaggacctgtaaagaaaggtgtagtggaccagaaggatgcaagtcttatgtgttctgt ctcccagacccttacgggtgttcctgtgccacaggctggagggggttgcagtgcaatgaa gcatgcccatctggttactacggaccagactgtaagctcaggtgccactgtaccaatgaa gagatatgtgatcggttccaaggatgcctctgctctcaaggatggcaagggctgcagtgt gagaaagaaggcaggccaaggatgactccacagatagaggatttgccagatcacattgaa gtaaacagtggaaaatttaaccccatctgcaaagcctctgggtggccactacctactagt gaagaaatgaccctagtgaagccagatgggacagtgctccaaccaaatgacttcaactat acagatcgtttctcagtggccatattcactgtcaaccgagtcttacctcctgactcagga gtctgggtctgcagtgtgaacacagtggctgggatggtggaaaagcctttcaacatttcc gtcaaagttcttccagagcccctgcacgccccaaatgtgattgacactggacataacttt gctatcatcaatatcagctctgagccttactttggggatggacccatcaaatccaagaag cttttctataaacctgtcaatcaggcctggaaatacattgaagtgacgaatgagattttc actctcaactacttggagccgcggactgactacgagctgtgtgtgcagctggcccgtcct ggagagggtggagaagggcatcctgggcctgtgagacgatttacaacagcgtctatcgga ctccctcctccaagaggtctcagtctcctgccaaaaagccagacagctctaaatttgact tggcaaccgatatttacaaactcagaagatgaattttatgtggaagtcgagaggcgatcc ctgcaaacaacaagtgatcagcagaacatcaaagtgcctgggaacctgacctcggtgcta ctgagcaacttagtccccagggagcagtacacagtccgagctagagtcaacaccaaggcg cagggggagtggagtgaagaactcagggcctggacccttagtgacattctccctcctcaa ccagaaaacatcaagatctccaacatcactgactccacagctatggtttcttggacaata gtggatggctattcgatttcttccatcatcatccggtataaggttcagggcaaaaatgaa gaccagcacattgatgtgaagatcaagaatgctaccgttactcagtaccagctcaagggc ctagagccagagactacataccatgtggatatttttgctgagaacaacataggatcaagc aacccagccttttctcatgaactgaggacgcttccacattccccagcctctgcagacctc ggagggggaaagatgctactcatagccatccttgggtcggctggaatgacttgcatcacc gtgctgttggcgtttctgattatgttgcaactgaagagagcaaatgtccaaaggagaatg gctcaggcattccagaacagagaagaaccagctgtgcagtttaactcaggaactctggcc cttaacaggaaggccaaaaacaatccggatcccacaatttatcctgtgcttgactggaat gacatcaagtttcaagacgtgatcggagagggcaactttggccaggttctgaaggcacgc atcaagaaggatgggttacggatggatgccgccatcaagaggatgaaagagtatgcctcc aaagatgatcacagggacttcgcaggagaactggaggttctttgtaaacttggacaccat ccaaacatcattaatctcttgggagcatgtgaacaccgaggctatttgtacctagctatt gagtatgccccgcatggaaacctcctggacttcctgcgtaagagcagagtgctagagaca gaccctgcttttgccatcgccaacagtacagcttccacactgtcctcccaacagcttctt cattttgctgcagatgtggcccgggggatggactacttgagccagaaacagtttatccac agggacctggctgccagaaacattttagttggtgaaaactacatagccaaaatagcagat tttggattgtcacgaggtcaagaagtgtatgtgaaaaagacaatgggaaggctcccagtg cgttggatggcaatcgaatcactgaactatagtgtctatacaaccaacagtgatgtctgg tcctatggtgtattgctctgggagattgttagcttaggaggcaccccctactgcggcatg acgtgcgcggagctctatgagaagctaccccagggctacaggctggagaagcccctgaac tgtgatgatgaggtgtatgatctaatgagacagtgctggagggagaagccttatgagaga ccatcatttgcccagatattggtgtccttaaacaggatgctggaagaacggaagacatac gtgaacaccacactgtatgagaagtttacctatgcaggaattgactgctctgcggaagaa gcagcctag

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