Mus musculus (house mouse): 21812
Help
Entry
21812 CDS
T01002
Symbol
Tgfbr1, ALK5, Alk-5, ESK2, TGFR-1, TbetaR-I, TbetaRI
Name
(RefSeq) transforming growth factor, beta receptor I
KO
K04674
TGF-beta receptor type-1 [EC:
2.7.11.30
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04010
MAPK signaling pathway
mmu04060
Cytokine-cytokine receptor interaction
mmu04068
FoxO signaling pathway
mmu04144
Endocytosis
mmu04218
Cellular senescence
mmu04350
TGF-beta signaling pathway
mmu04371
Apelin signaling pathway
mmu04380
Osteoclast differentiation
mmu04390
Hippo signaling pathway
mmu04520
Adherens junction
mmu04659
Th17 cell differentiation
mmu04926
Relaxin signaling pathway
mmu04933
AGE-RAGE signaling pathway in diabetic complications
mmu05142
Chagas disease
mmu05161
Hepatitis B
mmu05166
Human T-cell leukemia virus 1 infection
mmu05200
Pathways in cancer
mmu05210
Colorectal cancer
mmu05212
Pancreatic cancer
mmu05220
Chronic myeloid leukemia
mmu05225
Hepatocellular carcinoma
mmu05226
Gastric cancer
mmu05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
21812 (Tgfbr1)
04390 Hippo signaling pathway
21812 (Tgfbr1)
04068 FoxO signaling pathway
21812 (Tgfbr1)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
21812 (Tgfbr1)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
21812 (Tgfbr1)
09152 Endocrine system
04926 Relaxin signaling pathway
21812 (Tgfbr1)
09158 Development and regeneration
04380 Osteoclast differentiation
21812 (Tgfbr1)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
21812 (Tgfbr1)
09162 Cancer: specific types
05210 Colorectal cancer
21812 (Tgfbr1)
05212 Pancreatic cancer
21812 (Tgfbr1)
05225 Hepatocellular carcinoma
21812 (Tgfbr1)
05226 Gastric cancer
21812 (Tgfbr1)
05220 Chronic myeloid leukemia
21812 (Tgfbr1)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
21812 (Tgfbr1)
05161 Hepatitis B
21812 (Tgfbr1)
09174 Infectious disease: parasitic
05142 Chagas disease
21812 (Tgfbr1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
21812 (Tgfbr1)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
21812 (Tgfbr1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
21812 (Tgfbr1)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
21812 (Tgfbr1)
Protein kinases [BR:
mmu01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR1 family [OT]
21812 (Tgfbr1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
TGF_beta_GS
Activin_recp
Pkinase_fungal
APH
FTA2
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
21812
NCBI-ProteinID:
NP_033396
MGI:
98728
Ensembl:
ENSMUSG00000007613
UniProt:
Q64729
Q4FJL1
LinkDB
All DBs
Position
4:47353258..47414926
Genome browser
AA seq
503 aa
AA seq
DB search
MEAAAAAPRRPQLLIVLVAAATLLPGAKALQCFCHLCTKDNFTCETDGLCFVSVTETTDK
VIHNSMCIAEIDLIPRDRPFVCAPSSKTGAVTTTYCCNQDHCNKIELPTTGPFSEKQSAG
LGPVELAAVIAGPVCFVCIALMLMVYICHNRTVIHHRVPNEEDPSLDRPFISEGTTLKDL
IYDMTTSGSGSGLPLLVQRTIARTIVLQESIGKGRFGEVWRGKWRGEEVAVKIFSSREER
SWFREAEIYQTVMLRHENILGFIAADNKDNGTWTQLWLVSDYHEHGSLFDYLNRYTVTVE
GMIKLALSTASGLAHLHMEIVGTQGKPAIAHRDLKSKNILVKKNGTCCIADLGLAVRHDS
ATDTIDIAPNHRVGTKRYMAPEVLDDSINMKHFESFKRADIYAMGLVFWEIARRCSIGGI
HEDYQLPYYDLVPSDPSVEEMRKVVCEQKLRPNIPNRWQSCEALRVMAKIMRECWYANGA
ARLTALRIKKTLSQLSQQEGIKM
NT seq
1512 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcggccgctgctccacgtcgtccgcagctcctcatcgtgttggtggcggcg
gcgacgctgctcccgggggcgaaggcattacagtgtttctgccacctctgtacaaaggat
aattttacctgtgagacagatggtctttgctttgtctcagtcactgagaccacagacaaa
gttatacacaatagtatgtgtatagctgaaattgacctaattcctcgagacaggccattt
gtatgtgcaccatcttcaaaaacaggggcagttactacaacatattgctgcaatcaggac
cactgcaataaaatagaactcccaactacaggacctttttcagaaaagcagtcagctggc
cttggtcctgtggagctggcagctgtcattgctggtccagtctgcttcgtctgcattgca
cttatgctgatggtctatatctgccataaccgcactgtcattcaccaccgtgtgccaaat
gaagaggatccatcactagatcgccctttcatttcagagggcaccaccttaaaagattta
atttatgatatgacaacatcagggtctggatcaggtttaccactgcttgttcaaagaaca
attgccaggaccattgtgttacaagaaagcattggcaaaggtcggtttggagaagtttgg
cgaggcaaatggcggggagaagaagttgctgtgaagatattctcttctagagaagagcgt
tcatggttccgagaggcagagatttatcagactgtaatgttacgccatgaaaatatcctg
ggatttatagcagcagacaacaaagacaatgggacatggacgcagctgtggttggtgtca
gattatcatgagcatggatcccttttcgattacttgaatagatacactgttactgtggaa
ggaatgatcaagcttgctctgtccacagcaagtggtcttgcccatcttcacatggagatt
gttggtacccaaggaaaaccagctattgcccatagagatttgaaatcaaagaatatcttg
gtgaagaaaaatggaacctgttgtattgcagacttgggacttgctgtgagacatgattct
gccacagatacaattgatattgctccaaaccacagagtaggcactaaaaggtacatggcc
cctgaagttctagatgattccataaatatgaaacattttgaatccttcaaacgcgctgac
atctatgcaatgggcttagtgttctgggaaattgctcgacgctgttctattggtggaatc
catgaagactatcagttgccttattatgatcttgtaccttctgatccatcggttgaagaa
atgagaaaagtagtttgcgaacagaagttaaggccaaatattccaaacagatggcagagc
tgtgaggccttgagagtgatggctaaaattatgagagaatgctggtatgccaatggagca
gcaaggctgacagctttgcgaattaaaaaaacattgtcacaactcagccaacaggaaggc
atcaaaatgtaa
Mus musculus (house mouse): 21813
Help
Entry
21813 CDS
T01002
Symbol
Tgfbr2, 1110020H15Rik, DNIIR, RIIDN, TBR-II, TbetaR-II, TbetaRII
Name
(RefSeq) transforming growth factor, beta receptor II
KO
K04388
TGF-beta receptor type-2 [EC:
2.7.11.30
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04010
MAPK signaling pathway
mmu04060
Cytokine-cytokine receptor interaction
mmu04068
FoxO signaling pathway
mmu04144
Endocytosis
mmu04218
Cellular senescence
mmu04350
TGF-beta signaling pathway
mmu04380
Osteoclast differentiation
mmu04390
Hippo signaling pathway
mmu04520
Adherens junction
mmu04659
Th17 cell differentiation
mmu04926
Relaxin signaling pathway
mmu04933
AGE-RAGE signaling pathway in diabetic complications
mmu05142
Chagas disease
mmu05161
Hepatitis B
mmu05166
Human T-cell leukemia virus 1 infection
mmu05200
Pathways in cancer
mmu05202
Transcriptional misregulation in cancer
mmu05210
Colorectal cancer
mmu05212
Pancreatic cancer
mmu05220
Chronic myeloid leukemia
mmu05225
Hepatocellular carcinoma
mmu05226
Gastric cancer
mmu05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04350 TGF-beta signaling pathway
21813 (Tgfbr2)
04390 Hippo signaling pathway
21813 (Tgfbr2)
04068 FoxO signaling pathway
21813 (Tgfbr2)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
21813 (Tgfbr2)
09150 Organismal Systems
09151 Immune system
04659 Th17 cell differentiation
21813 (Tgfbr2)
09152 Endocrine system
04926 Relaxin signaling pathway
21813 (Tgfbr2)
09158 Development and regeneration
04380 Osteoclast differentiation
21813 (Tgfbr2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
21813 (Tgfbr2)
05202 Transcriptional misregulation in cancer
21813 (Tgfbr2)
09162 Cancer: specific types
05210 Colorectal cancer
21813 (Tgfbr2)
05212 Pancreatic cancer
21813 (Tgfbr2)
05225 Hepatocellular carcinoma
21813 (Tgfbr2)
05226 Gastric cancer
21813 (Tgfbr2)
05220 Chronic myeloid leukemia
21813 (Tgfbr2)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
21813 (Tgfbr2)
05161 Hepatitis B
21813 (Tgfbr2)
09174 Infectious disease: parasitic
05142 Chagas disease
21813 (Tgfbr2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
21813 (Tgfbr2)
09167 Endocrine and metabolic disease
04933 AGE-RAGE signaling pathway in diabetic complications
21813 (Tgfbr2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
mmu01001
]
21813 (Tgfbr2)
Enzymes [BR:
mmu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.30 receptor protein serine/threonine kinase
21813 (Tgfbr2)
Protein kinases [BR:
mmu01001
]
Receptor serine/threonine kinases (RSTK): TKL group
TGFBR2 family [OT]
21813 (Tgfbr2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
ecTbetaR2
PK_Tyr_Ser-Thr
Pkinase
ABC1
Haspin_kinase
Pkinase_fungal
APH
Motif
Other DBs
NCBI-GeneID:
21813
NCBI-ProteinID:
NP_083851
MGI:
98729
Ensembl:
ENSMUSG00000032440
UniProt:
Q62312
Q543C0
Q8BQS9
Q3UG22
LinkDB
All DBs
Position
9:complement(115916763..116004431)
Genome browser
AA seq
567 aa
AA seq
DB search
MGRGLLRGLWPLHIVLWTRIASTIPPHVPKSVNSDVMASDNGGAVKLPQLCKFCDVRLST
CDNQKSCMSNCSITAICEKPHEVCVAVWRKNDKNITLETVCHDPKLTYHGFTLEDAASPK
CVMKEKKRAGETFFMCACNMEECNDYIIFSEEYTTSSPDLLLVIIQVTGVSLLPPLGIAI
AVIIIFYCYRVHRQQKLSPSWESSKPRKLMDFSDNCAIILEDDRSDISSTCANNINHNTE
LLPIELDTLVGKGRFAEVYKAKLKQNTSEQFETVAVKIFPYEEYSSWKTEKDIFSDINLK
HENILQFLTAEERKTELGKQYWLITAFHAKGNLQEYLTRHVISWEDLRKLGSSLARGIAH
LHSDHTPCGRPKMPIVHRDLKSSNILVKNDLTCCLCDFGLSLRLDPTLSVDDLANSGQVG
TARYMAPEVLESRMNLENVESFKQTDVYSMALVLWEMTSRCNAVGEVKDYEPPFGSKVRE
HPCVESMKDSVLRDRGRPEIPSFWLNHQGIQIVCETLTECWDHDPEARLTAQCVAERFSE
LEHPERLSGRSCSQEKIPEDGSLNTTK
NT seq
1704 nt
NT seq
+upstream
nt +downstream
nt
atgggtcgggggctgctccggggcctgtggccgctgcatatcgtcctgtggacgcgcatc
gccagcacgatcccgccgcacgttcccaagtcggttaacagtgatgtcatggccagcgac
aatggcggtgcggtcaagcttccacagctgtgcaagttttgcgatgtgagactgtccact
tgcgacaaccagaagtcctgcatgagcaactgcagcatcacggccatctgtgagaagccg
catgaagtctgcgtggccgtgtggaggaagaacgacaagaacattactctggagacggtt
tgccacgaccccaagctcacctaccacggcttcactctggaagatgccgcttctcccaag
tgtgtcatgaaggaaaagaaaagggcgggcgagactttcttcatgtgtgcctgtaacatg
gaagagtgcaacgattacatcatcttttcggaagaatacaccaccagcagtcccgacctg
ttgttggtcattatccaagtgacgggtgtcagcctcctgcctccgctggggattgccata
gctgtcatcatcatcttctactgctaccgtgtccaccggcagcagaagctgagcccgtcc
tgggagagcagcaagccccggaaactgatggatttcagtgacaattgtgccatcatcctg
gaggacgaccgctccgacatcagctccacgtgcgccaacaacatcaaccacaacacggag
ctgctgcccatcgagctggacacgctggtggggaagggccgcttcgccgaggtctacaag
gccaagctgaagcagaacacctcagagcagtttgagaccgtggctgtcaagatcttcccc
tacgaggagtactcctcgtggaaaacagagaaggacatcttctccgatatcaacctgaag
catgagaacatcctgcagttcctgacggccgaggagcggaagacagagctgggcaagcag
tactggctgatcacggcgttccacgcgaagggcaacctgcaggagtacctcacgaggcat
gtcatcagctgggaggacctgaggaagctgggcagctccctggcccggggcatcgctcat
ctccacagtgaccacactccttgtgggaggcccaagatgcccattgttcacagggacctc
aagagctctaacatcctagtgaagaacgacttgacctgttgcctgtgtgacttcgggctg
tccttgcgcctggaccctactctgtctgtggatgacctggccaacagcgggcaggtggga
acggcaagatacatggccccggaagttctagaatccaggatgaatctggaaaacgtggag
tcgttcaagcagacggatgtctactccatggctctggtactctgggaaatgacgtcccgc
tgcaatgctgtgggagaagtgaaggattacgagcccccatttggttccaaggtgcgggag
cacccctgtgtggagagcatgaaagacagtgtgctgagagaccgagggcggccggaaatt
cccagcttctggctcaaccaccagggcatccagatcgtgtgtgagactttgaccgagtgc
tgggaccatgaccccgaagcccgtctcacagcacagtgtgtggcagagcgcttcagtgag
ctggagcatccggagagactctctgggaggagctgctcccaggagaagattccagaagat
ggctcgctgaacactaccaaatag
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integrated database retrieval system
