Mus musculus (house mouse): 21974
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Entry
21974 CDS
T01002
Symbol
Top2b, D230016L12Rik, Top-2
Name
(RefSeq) topoisomerase (DNA) II beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
21974 (Top2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mmu03032
]
21974 (Top2b)
03036 Chromosome and associated proteins [BR:
mmu03036
]
21974 (Top2b)
Enzymes [BR:
mmu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
21974 (Top2b)
DNA replication proteins [BR:
mmu03032
]
Eukaryotic type
DNA Topoisomerases
21974 (Top2b)
Chromosome and associated proteins [BR:
mmu03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
21974 (Top2b)
Centrosome formation proteins
Centriole proteins
21974 (Top2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Microp_apicomplexa_20
Motif
Other DBs
NCBI-GeneID:
21974
NCBI-ProteinID:
NP_033435
MGI:
98791
Ensembl:
ENSMUSG00000017485
UniProt:
Q64511
LinkDB
All DBs
Position
14:complement(6038976..6104585)
Genome browser
AA seq
1612 aa
AA seq
DB search
MAKSSLAGSDGALTWVNNATKKEELETANKNDSTKKLSVERVYQKKTQLEHILLRPDTYI
GSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDP
ESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCN
IFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKL
DKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHE
LANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVSKLIEVVKKKNKAGVSV
KPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESI
LNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVS
GLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTL
RYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYS
IPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITL
AFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDN
ERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNL
AQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYD
DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPHPMLPN
YKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTP
ALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKK
YETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKK
DLIQMLVQRGYESDPVKAWKEAQEKAAEEEDSQNQHDDSSSDSGTPSGPDFNYILNMSLW
SLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMS
GKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDPDTTVVKV
EFDEEFSGTPAEGTGEETLTPSAPVNKGPKPKREKKEPGTRVRKTPTSTGKTNAKKVKKR
NPWSDDESKSESDLEEAEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDAAAADDSNDLE
ELKVKASPITNDGEDEFVPSDGLDKDEYAFSSGKSKATPEKSSNDKKSQDFGNLFSFPSY
SQKSEDDSAKFDSNEEDTASVFAPSFGLKQTDKLPSKTVAAKKGKPPSDTAPKAKRAPKQ
KKIVETINSDSDSEFGIPKKTTTPKGKGRGAKKRKASGSENEGDYNPGRKPSKTASKKPK
KTSFDQDSDVDIFPSDFTSEPPALPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4839 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtccagcctcgcgggctctgacggggcgctgacctgggtgaacaatgctaca
aaaaaggaagagttggagacagcaaacaaaaatgactctactaagaagttgtctgttgag
agagtgtaccagaagaagacccaactggagcacattctccttcgtcctgatacatacatt
ggatcagtggagccactgacacagctaatgtgggtgtatgatgaagatgtagggatgaac
tgcagggaggtcacctttgttccaggcttatacaagatctttgatgaaattttggttaat
gctgctgacaacaagcagagggacaagaacatgacctgtattaaggtttctattgatcct
gaatctaatattataagcatttggaataatgggaaaggcattccagtagtagaacacaaa
gtagagaaagtttatgttcctgctttaatttttggacagcttttaacatcgagtaattat
gacgatgatgagaaaaaagttacaggaggccgtaatggttatggtgcaaagctttgtaat
atttttagtacaaagtttacagtagaaacggcttgcaaagaatacaaacatagttttaaa
cagacatggatgaataatatgatgaagacttctgaagccaaaattaaacattttgatggt
gaagattatacatgcataacattccagccagatctatccaaatttaagatggaaaaactt
gacaaggacattgtggccctcatgaccagaagagcatatgatttagctgggtcctgtaaa
ggagtcaaggtcatgtttaatgggaagaagttgcctgtaaatggatttcgcagctatgta
gacctttatgtgaaagacaaattggatgaaactggggtggctctcaaagttattcatgaa
cttgcaaatgaaagatgggatgtttgtctaaccttgagtgaaaaaggtttccagcagatc
agctttgtgaatagtattgcaactacaaaaggtgggcggcatgtggattatgtagtagat
caagttgttagtaaactgattgaagtagttaagaaaaagaacaaagctggtgtatcagtg
aaaccatttcaggttaaaaaccatatatgggtttttattaattgtcttattgaaaatcca
acctttgattctcaaactaaggaaaacatgactctgcagcccaaaagttttgggtccaaa
tgccaactgtcagaaaaattttttaaagcagcctctaattgtggcattgtagaaagcata
ttgaactgggtgaaatttaaggctcagactcaactgaataagaagtgttcatcagtaaag
tacagtaaaatcaaaggcattcccaaactggatgatgccaatgatgctggtggcaaacat
tccctggagtgtacattaatattaacagagggggactccgccaaatctctagctgtatct
ggattaggtgtgattggtagggacagatatggagtcttcccactcaggggtaaaattctc
aatgtacgagaagcctctcataaacagattatggaaaatgcagagataaataatattatt
aaaatagttggtttgcaatacaagaaaagttatgatgatgcagaatctctgaaaacttta
cgttatggaaagattatgattatgactgatcaggatcaagatggttctcacatcaaaggc
ctgctaatcaattttattcatcacaattggccatcacttttgaagcatggttttcttgaa
gaattcattactcccattgtaaaggcaagcaaaaataagcaggaactttccttttatagt
attcctgaatttgatgagtggaaaaaacatatagaaaaccagaaagcctggaaaataaag
tactacaaaggattaggtaccagtaccgctaaagaagcaaaggaatattttgctgatatg
gaaaggcatcgcattttgtttagatatgctggacctgaagatgatgctgccatcaccttg
gcatttagtaagaagaagattgatgacagaaaagagtggttaaccaactttatggaggat
cggagacagcgtaggttacatggcctaccagagcaatttttatatggtacagcaacaaag
catttgacatacaatgatttcatcaacaaggaattgattctcttctcaaactcggacaat
gagagatctatcccatctcttgtggatggcttcaagccaggtcaacgaaaagttttgttt
acctgtttcaagaggaatgataaacgtgaagtgaaagtagcgcagctggctggatctgtt
gctgagatgtctgcttaccaccatggagaacaagcattgatgatgactattgtgaatttg
gctcagaattttgtgggcagtaataacattaacttgcttcagcccattggtcagtttgga
actcggcttcatggtggcaaagatgctgcaagccctcgttatattttcacaatgttgagc
tctctggcaagacttctttttccagctgtggatgataacttgcttaagttcctttatgat
gataatcaacgtgtagagccagagtggtatatccctataatccccatggttttgattaat
ggtgctgagggtattgggactggatgggcttgtaaactgcccaactatgatgctagagaa
attgtgaacaatgtcaggcggatgctagaaggtttggatcctcatcccatgcttccaaac
tataagaacttcaaaggcaccatccaggaacttggtcagaaccagtatgctgttagtggt
gagatatttgtggtggacagaaacacagtagagattacagaacttccagttagaacatgg
acacaggtatacaaggagcaggtcctagaacctatgcttaatggaacagataaaacaccg
gcactgatttctgattacaaagaatatcatactgacacaactgtgaagtttgtggtgaaa
atgacagaagagaaactagcgcaagcagaagctgctggcctgcataaagtttttaaactt
caaactactcttacttgcaattccatggtactctttgatcatatgggttgtctgaagaag
tatgaaactgtgcaagacattttgaaagaattctttgatttacggttaagttattatggt
ttacggaaggaatggcttgtaggaatgctgggagcagaatctacaaagcttaataatcaa
gcccgtttcattttagagaagatacaggggaaaattactatagagaataggtcaaagaaa
gatttgattcaaatgttagtccagagaggttatgaatctgacccagtgaaagcgtggaaa
gaagcacaagaaaaggctgcagaagaggaagattcacaaaaccaacatgatgacagttcc
tctgattcaggaactccttcaggccctgattttaattatattttaaatatgtctctatgg
tctcttactaaagaaaaagttgaagaactcattaaacagagagatacgaaagggcgagag
gttaatgatctcaagaggaagtctccttcagatctttggaaagaagacttagcagcattt
gttgaagaattggataaagtggaagcacaagagcgggaagatattctggcaggaatgtct
gggaaagcaataaaaggtaaagtcggcaaacccaaagtaaagaaacttcagctggaggag
acaatgccctcgccttacgggagaagaattgttccagagattactgctatgaaggcagat
gccagcagaaaattgctgaagaagaaaaagggtgatcctgataccacagtagtgaaagta
gaatttgatgaagaatttagtggaacaccagcagaaggtacaggagaggagacattgacc
ccatctgctcctgtaaataaaggccccaaacccaaaagagagaagaaggagcctggtacc
agggttagaaaaacacctacatcaactggtaaaactaatgcgaagaaagtgaagaaacgg
aatccttggtcagatgatgagtccaaatcagagagtgacttggaagaagcagaacctgtg
gttatcccaagagattctttgcttaggagagcagctgctgaaagacctaagtacactttt
gatttctcagaagaggaggatgatgatgctgctgctgctgatgacagtaatgatttagaa
gaactgaaagttaaagcatctcccataacaaatgatggggaagatgaatttgttccttca
gatggcttagataaagatgagtatgctttttcttcaggcaaatccaaagctactccagaa
aaatcttcaaatgacaaaaaaagtcaggattttggaaatcttttttcatttccttcatat
tctcagaagtcagaagatgattcagctaaatttgacagtaatgaagaagataccgcttct
gtttttgctccatcatttggtctgaagcaaacagataaacttccaagtaaaacagttgct
gctaaaaagggtaaaccaccttcagatacagcccctaaagctaagagagcccctaaacag
aagaagatagtagagactataaactctgactcagactctgaatttggcattccaaagaag
actacaacaccaaaaggtaaaggccgaggggcaaagaaaaggaaagcatcaggctcagaa
aatgaaggtgattataaccctggaaggaaaccatctaaaacagccagcaagaaaccgaag
aaaacatcttttgatcaggattcagatgtagacatcttcccctcagacttcacttctgaa
ccaccggctctcccacggactggtcgggctaggaaagaagtaaaatattttgcagagtct
gatgaagaagaagatgttgattttgcaatgtttaattaa
DBGET
integrated database retrieval system
