Mus musculus (house mouse): 21975
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Entry
21975 CDS
T01002
Symbol
Top3a
Name
(RefSeq) DNA topoisomerase 3-alpha
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu03440
Homologous recombination
mmu03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
21975 (Top3a)
03460 Fanconi anemia pathway
21975 (Top3a)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
mmu03032
]
21975 (Top3a)
03400 DNA repair and recombination proteins [BR:
mmu03400
]
21975 (Top3a)
Enzymes [BR:
mmu01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
21975 (Top3a)
DNA replication proteins [BR:
mmu03032
]
Eukaryotic type
DNA Topoisomerases
21975 (Top3a)
DNA repair and recombination proteins [BR:
mmu03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
21975 (Top3a)
FA (Fanconi anemia) pathway
21975 (Top3a)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Toprim
Zn_ribbon_Top1
Zn_ribbon_GRF_2
zf-C2H2_10
Motif
Other DBs
NCBI-GeneID:
21975
NCBI-ProteinID:
NP_033436
MGI:
1197527
Ensembl:
ENSMUSG00000002814
UniProt:
O70157
Q5NCT2
LinkDB
All DBs
Position
11:complement(60629014..60668099)
Genome browser
AA seq
1003 aa
AA seq
DB search
MIFPVTLLAFQWHRRPGGRALSRAAMEVAFRGVRKVLCVAEKNDAAKGIADLLSNGRMRR
KEGLSKFNKIYEFDYHLYGQNVTMIMTSVSGHLLAHDFQMQFRKWQSCNPLVLFEAEIEK
YCPENFIDIKKTLERETHHCQALVIWTDCDREGENIGFEIIHVCKAVKPNLRVLRARFSE
ITPHAVRTACENLTEPDQRVSDAVDVRQELDLRIGAAFTRFQTLRLQRIFPEVLAEQLIS
YGSCQFPTLGFVVERFKAIQAFVPEVFHKIKVTHDHKDGTVEFNWKRYRLFNHTACLVLY
QLCMEDPMATVVEVRSKPKSKWRPQALDTVELEKLASRKLRINAKETMRIAEKLYTQGYI
SYPRTETNIFPKDLNLVALVEQQTVDPHWGAFAQTILERGGPTPRNGSKSDQAHPPIHPT
KYTSGLQGDDRRLYEFIVRHFLACCSQDAQGQETTVEIDIAQERFVAHGLIILARNYLDV
YPYDHWSDKLLPVYEQGSHFQPSTVEMVDGETSPPQLLTEADLIALMEKHGIGTDATHAE
HIETIKARMYVGLTSDKRFLPGHLGMGLVEGYDSMGYEMSKPDLRAELEADLKLICEGKK
DKFQVLRQQVQKYKQVFIEAVAKAKKLDEALSQYLGERTEMAQQEEIYPAMPEPVRKCPQ
CNKDMVLKTKKSGGFYLSCMGFPECRSAVWFPDSVLEASRDNSVCSVCQPPPVYRLKLKF
KRGSLPPAMPLEFVGCIGGCDETLKEIFGLRFPRALPRASQPSGHLQASQALNRMDSSQH
NLSQPLVNRHTRPSKTVAQALLPPTTAGESNSVTCNCGREAVLLTVRKQGPNQGRHFYKC
SNGDCNFFLWADSSHSTGGGTPTSASGPPGSSVGCPSSVGSHMDGFGSLGSDSDGGTPCL
CGQPAVTRTVQKDGPNKGRQFHTCAKPREQQCGFFQWVDENVAPGSFAAPAWPGGRGKAQ
RPEAASKRPRAGSSDAGSTVKKPRKCSLCHQPGHTRTFCPQNR
NT seq
3012 nt
NT seq
+upstream
nt +downstream
nt
atgatcttcccggtcaccctcttagcgtttcagtggcaccgacggcctggaggccgtgcc
ctgtcccgcgctgccatggaagtggccttccgaggagtgcgaaaagttctctgcgtggcg
gagaaaaacgacgctgccaaggggatcgccgacttgctgtccaacgggcgtatgaggcgg
aaagaaggcctttctaaattcaacaagatttatgaatttgactatcatctgtatggccag
aatgttactatgataatgacttcagtctctggacatttgctggctcatgacttccagatg
cagtttcggaaatggcagagctgcaatccccttgtcctctttgaagcagaaattgaaaag
tattgcccagaaaattttatagacatcaagaaaactctagaacgagagacacatcattgt
caggccctggtgatctggacggactgtgatagggaaggtgagaacatcggctttgagatt
atccacgtatgcaaggctgtaaaacccaatctacgggtgctgagagcccgcttctctgag
atcacgccacacgccgtcagaacagcctgtgaaaacctaactgagcctgaccagagagtg
agtgacgcagtggatgtgaggcaagagctggacctgaggatcggagctgccttcacaagg
ttccagaccctgcggctccagaggatcttccctgaggtgctggcagagcagctcatcagc
tacggcagttgccagttcccaacactggggtttgtggtggagaggttcaaggccattcag
gcttttgtgccagaagtcttccacaaaattaaagtaactcatgaccacaaagatgggacc
gtagagttcaactggaaacgataccgtctctttaaccacacagcttgtcttgtcctttat
cagttgtgcatggaggatcccatggcgactgtggtagaggtcagatctaagccaaagagc
aagtggaggccgcaggctttggacacggtggagctagagaaactggcatctcggaaattg
agaataaatgccaaagaaaccatgaggatcgcggaaaagctctatacacaagggtacatc
agctacccccggacagaaacaaacatcttccccaaagacttaaacctggttgcattggta
gaacagcagaccgtggatccacactggggggcttttgctcagaccattctagagcgaggt
ggccctactccccgaaacgggagcaagtctgatcaagctcaccctcccattcaccccacc
aaatacaccagcggcttgcagggagatgatcggcgactgtacgagttcattgttcgccat
ttcctggcttgctgctctcaggacgctcaggggcaagagactaccgtagagatcgacatt
gcccaagagcgctttgtggcccacgggctcatcattctggcccgtaactacctagatgtg
tatccgtatgatcactggagtgacaagctcctccccgtctatgaacaaggctcccacttc
cagcccagcactgtggaaatggtggatggagagactagcccaccccaactgcttaccgaa
gctgacctcatcgccctcatggagaaacatgggatcggtactgatgcaactcatgcagaa
cacattgagaccatcaaagcccggatgtatgtgggactcacctcagacaagcggttcctg
ccggggcacctgggcatgggacttgtagaaggttacgattccatgggttatgagatgtcc
aagcctgacctccgtgccgagctggaagctgatctcaagctgatctgtgagggcaagaag
gataagtttcaagttctaaggcagcaagtgcaaaaatacaagcaggttttcattgaagca
gtggcgaaggcaaagaagttggatgaggctttatctcagtacttaggagaaagaacagag
atggcccagcaagaagagatctacccagccatgccagagcctgttcggaagtgcccacag
tgtaacaaggatatggtcctcaagaccaagaagagtggtgggttctacctcagctgcatg
gggttcccagagtgtcggtcagctgtgtggtttcctgactcggtgctggaggccagcagg
gacaacagtgtgtgttctgtttgtcagccaccccctgtgtacaggttgaagttgaagttt
aagcgtggtagccttcccccagctatgcccctggagtttgtcggctgcataggtggatgt
gatgagactttgaaggaaatcttcggcctgcgatttccacgggctctcccaagagctagc
cagccctctggccacctgcaggccagccaggccctcaacaggatggacagcagtcagcat
aacctgtctcaacctctggttaacagacatactagaccttcaaagacagtggcccaagcc
ttgctaccacccactactgctggtgaaagcaactctgtgacttgcaattgtggccgggag
gctgtgctgctcactgtccgcaagcagggccccaaccagggccggcatttctacaagtgc
agtaatggtgactgcaacttcttcctgtgggctgacagcagccattccactggaggaggg
acccccacctctgcatcaggacccccaggcagctctgtaggatgcccatccagtgtaggc
agccacatggatgggtttggcagccttggcagcgacagtgatggaggtacaccctgcctg
tgcgggcagcctgctgtcacacggactgttcagaaggatggacccaacaaaggacgccag
ttccacacctgtgccaagccacgagagcagcagtgtggcttctttcagtgggtggatgag
aatgtggccccaggaagttttgcagcccctgcatggccaggaggcagaggaaaagcccag
agaccagaggctgcaagcaaaagaccaagagctggttcctcagatgcagggtccacagta
aaaaagcctcggaaatgtagcctttgtcaccagcctggacacacccgaaccttttgtcct
cagaacagatga
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integrated database retrieval system
