Mus musculus (house mouse): 22084 Help Entry 22084             CDS       T01002                                  Symbol Tsc2, Nafld, Tcs2 Name (RefSeq) TSC complex subunit 2   KO K07207   tuberous sclerosis 2 Organism mmu  Mus musculus (house mouse) Pathway mmu04072   Phospholipase D signaling pathway mmu04115   p53 signaling pathway mmu04140   Autophagy - animal mmu04150   mTOR signaling pathway mmu04151   PI3K-Akt signaling pathway mmu04152   AMPK signaling pathway mmu04211   Longevity regulating pathway mmu04218   Cellular senescence mmu04714   Thermogenesis mmu04910   Insulin signaling pathway mmu04919   Thyroid hormone signaling pathway mmu05163   Human cytomegalovirus infection mmu05165   Human papillomavirus infection mmu05168   Herpes simplex virus 1 infection mmu05231   Choline metabolism in cancer Brite KEGG Orthology (KO) [BR:mmu00001]  09130 Environmental Information Processing   09132 Signal transduction    04072 Phospholipase D signaling pathway     22084 (Tsc2)    04151 PI3K-Akt signaling pathway     22084 (Tsc2)    04152 AMPK signaling pathway     22084 (Tsc2)    04150 mTOR signaling pathway     22084 (Tsc2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     22084 (Tsc2)   09143 Cell growth and death    04115 p53 signaling pathway     22084 (Tsc2)    04218 Cellular senescence     22084 (Tsc2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     22084 (Tsc2)    04919 Thyroid hormone signaling pathway     22084 (Tsc2)   09149 Aging    04211 Longevity regulating pathway     22084 (Tsc2)   09159 Environmental adaptation    04714 Thermogenesis     22084 (Tsc2)  09160 Human Diseases   09161 Cancer: overview    05231 Choline metabolism in cancer     22084 (Tsc2)   09172 Infectious disease: viral    05168 Herpes simplex virus 1 infection     22084 (Tsc2)    05163 Human cytomegalovirus infection     22084 (Tsc2)    05165 Human papillomavirus infection     22084 (Tsc2)  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:mmu01009]     22084 (Tsc2) Protein phosphatases and associated proteins [BR:mmu01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      22084 (Tsc2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Tuberin DUF3384 Rap_GAP Cnd1 Motif Other DBs NCBI-GeneID:  22084 NCBI-ProteinID:  NP_001034452 MGI:  102548 Ensembl:  ENSMUSG00000002496 UniProt:  Q7TT21 Q3UGI8 LinkDB All DBs Position 17:complement(24814788..24851607) Genome browser AA seq 1742 aa AA seqDB search MAKPTSKDSGLKEKFKILLGLGTSRPNPRCAEGKQTEFIITSEILRELSGECGLNNRIRM IGQICDVAKTKKLEEHAVEALWKAVSDLLQPERPPEARHAVLTLLKAIVQGQGDRLGVLR ALFFKVIKDYPSNEDLHERLEVFKALTDNGRHITYLEEELAEFVLQWMDVGLSSEFLLVL VNLVKFNSCYLDEYIASMVHMICLLCIRTVSSVDIEVSLQVLDAVVCYNCLPAESLPLFI ITLCRTINVKELCEPCWKLMRNLLGTHLGHSAIYNMCRIMEDRSYMEDAPLLRGAVFFVG MALWGAHRLYSLKNSPTSVLPSFYEAMTCPNEVVSYEIVLSITRLIKKYRKELQAVTWDI LLDIIERLLQQLQNLDSPELKTIVHDLLTTVEELCDQNEFHGSQERYYELVESYADQRPE SSLLNLISYRAQSIHPAKDGWIQNLQLLMERFFRNECRSAVRIKVLDVLSFVLLINRQFY EEELINSVVISQLSHIPEDKDHQVRKLATQLLVDLAEGCHTHHFNSLLDIIEKVMARSLS PPPELEERDLAMHSASLEDVKTAVLGLLVILQTKLYTLPASHATRVYESLISHIQLHYKH GYSLPIASSIRLQAFDFLLLLRADSLHRLGLPNKDGVVRFSPYCLCDCMELDRASEKKAS GPLSPPTGPPSPVPMGPAVRLGYLPYSLLFRVLLQCLKQESDWKVLKLVLSRLPESLRYK VLIFTSPCSVDQLSSALCSMLSAPKTLERLRGTPEGFSRTDLHLAVVPVLTALISYHNYL DKTRQREMVYCLEQGLIYRCASQCVVALAICSVEMPDIIIKALPVLVVKLTHISATASMA IPLLEFLSTLARLPHLYRNFAAEQYASVFAISLPYTNPSKFNQYIVCLAHHVIAMWFIRC RLPFRKDFVPYITKGLRSNVLLSFDDTPEKDSFRARSTSLNERPKSRIQTSLTSASLGSA DENSMAQADDNLKNLHLELTETCLDMMARYVFSNFTAVPKRSPVGEFLLAGGRTKTWLVG NKLVTVTTSVGTGTRSLLGLDSGDLQGGSDSSSDPSTHVRQTKEAPAKLESQAGQQVSRG ARDRVRSMSGGHGLRVGVLDTSAPYSPGGSASLGPQTAVAAKPEKPPAGAQLPTAEKTNL AAYVPLLTQGWAEILVRRPTGNTSWLMSLENPLSPFSSDINNMPLQELSNALMAAERFKE HRDTALYKSLSVPAAGTAKPPTLPRSNTDSAMVLEEGSPGETQVPVEPPELEDFEAALGT DRHCQRPDTYSRSSSASSQEEKSHLEELAAGGIPIERAISSEGARPAVDLSFQPSQPLSK SSSSPELQTLQDILGDLGDKIDIGRLSPEAKVRSQSGILDGEAATWSATGEESRITVPPE GPLPSSSPRSPSGLRPRGYTISDSAPSRRGKRVERDNFKSRAAASSAEKVPGINPSFVFL QLYHSPFFGDESNKPILLPNESFERSVQLLDQIPSYDTHKIAVLYVGEGQSSSELAILSN EHGSYRYTEFLTGLGRLIELKDCQPDKVYLGGLDVCGEDGQFTYCWHDDIMQAVFHIATL MPTKDVDKHRCDKKRHLGNDFVSIIYNDSGEDFKLGTIKGQFNFVHVIITPLDYKCNLLT LQCRKDMEGLVDTSVAKIVSDRNLSFVARQMALHANMASQVHHSRSNPTDIYPSKWIARL RHIKRLRQRIREEVHYSNPSLPLMHPPAHTKAPAQAPEATPTYETGQRKRLISSVDDFTE FV NT seq 5229 nt NT seq  +upstreamnt  +downstreamnt atggccaaaccaacaagcaaagattccggcttgaaggagaagttcaagatactgttggga ttgggaacatcgaggccaaatcccaggtgtgcagaaggcaaacagactgagtttatcatc acatcggaaatcttgagagaactgagtggtgaatgcggcctcaacaatcgcatccgaatg atagggcagatctgtgatgtggcaaaaactaagaagcttgaggagcatgcagtggaggca ctttggaaggctgtctcagacttgctacagccagagcggccaccagaggcccggcatgca gttctcaccttattgaaggccattgtacagggacagggtgatcgtttgggagttctcaga gccctcttcttcaaagtgatcaaggactacccctccaatgaagacctccatgaaaggcta gaagtttttaaggccctcacagacaatgggaggcacattacctatttggaagaagaactg gcagagtttgtcctgcagtggatggatgttggcttgtcctcagaattccttctggtactt gtcaacctggtcaagttcaacagctgttaccttgacgaatacattgcatcaatggttcac atgatttgtctgctatgcatccggacagtgtcctctgtggacattgaggtgtccttgcaa gtgctggatgctgtggtctgctacaactgcttaccagccgagagcctgcctctgttcatt atcaccctgtgccgcaccatcaatgtcaaggagctgtgtgagccttgctggaagttgatg cgtaaccttctgggcacccacctgggccacagcgccatctacaacatgtgccgcatcatg gaggacagatcctacatggaagatgccccactgctgagaggagctgtgttctttgtaggg atggcactctggggagctcaccggctctactctctcaagaactcccccacatctgtgctg ccgtctttttatgaggctatgacctgtcccaatgaggtggtgtcatatgagattgttctg tccataacaagactcatcaagaagtataggaaggagctccaggctgtgacatgggatatt ctgctggacatcattgaacgactacttcagcaactccagaacctggacagcccggaactc aagaccatcgtccatgacctgctgaccactgtggaggagctatgtgaccagaacgagttc catggctcgcaggaaagatactatgaactggtggagagctatgcagaccagagacctgaa tcctctctcttaaacttgatatcctacagagcccagtccatccaccctgccaaggatggc tggatccagaacttgcagttgttgatggagaggttcttcaggaatgagtgccgcagcgcc gtgcgcatcaaggtgttggatgttctgtccttcgtgctgctgatcaacaggcagttctat gaggaggagctgattaactcggtggtcatctcgcagctctcccacattcccgaggataag gaccatcaggtccgaaagctggctactcagctgctggtggacctggcagaggggtgccac acccaccacttcaacagtctgctggacatcattgaaaaggtgatggcgcgctcactctct ccacccccggagctggaagaaagggacctggccatgcactcggcctccctggaggacgtg aagaccgcggtcctggggctcctggtcatccttcagaccaagctctacaccttgcctgcc agccacgccactcgagtgtatgagagcctcattagtcacatccagctccattacaagcac ggctactccctgcccattgctagcagcatccgactacaggcctttgacttcctgctgcta ctgcgggctgactcgctgcatcgactgggcctgcccaacaaggatggggtcgtgagattc agcccttactgcctctgtgactgcatggaactggatagagcctcagagaagaaagccagt gggcccctttcacctccaactgggccccctagccctgtgcctatgggccctgctgtgcgg ctcggctacctaccctactccctgctcttccgtgtcctgttgcagtgtttgaagcaggag agcgactggaaggtgctgaagctggtgctcagcaggctgccggagtcactgcgctacaaa gtcctcatcttcacctccccctgcagtgtcgaccagctgtcttctgccctctgctccatg ctttcagctccaaagacccttgagcggctccgaggtaccccagaaggcttctcgagaact gacctgcacttggctgtggttcccgtgctaacagcattaatatcttatcacaactatttg gacaagaccagacagcgtgagatggtgtactgcctggaacaaggccttatctaccgctgc gccagccagtgcgtggtagccttggccatctgcagtgtggagatgcccgacatcatcatc aaggcgcttcctgtcctggtggtgaagctcacacacatttctgccacagccagcatggcc atcccgctcctggagttcctgtctactttggccaggctgccccacctctacaggaacttt gctgcagagcagtatgccagcgtgtttgccatctccttgccatacaccaacccctccaag ttcaaccagtacattgtgtgtctggctcaccacgtcatagccatgtggttcatcaggtgc cgactgccctttcggaaggatttcgtcccttatatcactaagggtttgcgttccaatgtc ctcctgtcttttgatgatacccctgagaaggacagtttcagagcacggagcaccagtctt aatgagagacccaaaagcagaatacagacatcccttacgagcgccagcctggggtctgcg gatgagaactctatggcccaggctgatgacaacttgaagaatctccacttggagctcaca gaaacatgtctggacatgatggcccgatatgtgttctccaatttcactgcagtccccaag aggtcccctgtgggagagttcctcctggcagggggtaggaccaaaacctggctggttgga aacaagcttgtcactgtgacaacaagtgtgggaactggtacacggtcgctgctgggcctg gactctggggacctgcagggtggctcggattcaagctctgatcctagcacacatgtgagg cagacaaaggaagcaccggccaaactggagtcccaggctgggcagcaggtgtcccgtggg gcccgggaccgggtccgctccatgtcagggggccatggccttcgagttggtgtcctggat acttcagctccctattccccaggtggctctgcttctctgggaccacagacggcggtggca gcgaagcccgagaagccccctgcaggagcccagcttccaacagcagagaagacgaatctg gcagcctatgtgcctttgttaacccagggctgggcagaaatcttagtccgcagacccaca ggaaacaccagctggctgatgagcttggagaacccgctcagccccttctcctcagacatc aacaacatgcccctgcaagagctgtccaatgcccttatggctgctgaacgtttcaaggag caccgggacacggccctgtacaagtcattgtcagtgccagcggctggcaccgccaagcct cctactctcccacgctctaatacagactcagccatggtccttgaggagggaagtccagga gagactcaggtgccagtggagccccccgaattggaggatttcgaggcggcgttaggtaca gacaggcactgccagcggcctgacacctacagccggtcatcctcagcatctagccaggaa gaaaagtcccatttggaggagcttgctgcagggggtatccccattgagcgggccatctcc tctgagggggctcggcctgccgtggacctctccttccaaccctcacagcctttgagcaag tctagctcttctccggagttgcagaccttacaggacatccttggagacctaggggacaag attgatattggacggctgagtcctgaggctaaggtccggtcccagtcagggatcctggat ggggaagcagctacctggtcagctacgggtgaagagagccgtatcacagtcccacctgaa ggtcctctgccttccagttctccccgctcccccagtggcctccggccccgaggctatacc atctctgattccgctccatcacgaaggggaaagagggtagaaagggataacttcaagagc agagctgcggcctccagtgctgagaaggtgccaggcatcaaccctagctttgtgttccta cagctctaccattcgcccttttttggtgatgagtccaataagcccatcctattgcccaat gagtcctttgaacggtcagtacagctgcttgaccagattccatcctatgacactcacaag attgctgtcctgtatgtgggagaaggccagagcagcagtgagctggccatcctgtcaaat gagcatggctcttacaggtacacggagtttctgacaggcctgggtcggcttattgagctc aaggactgccaaccagacaaggtgtacttaggtggactggatgtatgtggcgaggatgga cagttcacctactgctggcatgatgacatcatgcaagctgttttccacattgccaccctg atgcccaccaaggatgtggacaagcaccgctgtgacaagaaacggcacctgggcaatgac tttgtttctatcatctacaatgattctggtgaggacttcaaactgggcaccattaagggc cagttcaactttgtccatgtgatcatcacaccgctggactacaagtgcaacctattgacc ctgcagtgcaggaaagacatggaaggcctcgtggacaccagtgtggccaagattgtgtct gaccgcaacctgtcctttgtggcccgacagatggccctgcatgcaaatatggcctcacag gtacaccacagccgatccaaccccactgacatctatccctccaagtggatcgcaagactc cgccacattaagcgtctccgccagaggatccgtgaagaggtgcactattccaacccaagc ttgcctctgatgcaccctccagcccacaccaaagccccagctcaagcccctgaggctaca cccacctatgaaacaggccagcggaagcgcctcatttcctccgtggatgacttcacagag tttgtgtga

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