Mus musculus (house mouse): 22171 Help Entry 22171             CDS       T01002                                  Symbol Tyms, Ts Name (RefSeq) thymidylate synthase   KO K00560   thymidylate synthase [EC:2.1.1.45] Organism mmu  Mus musculus (house mouse) Pathway mmu00240   Pyrimidine metabolism mmu00670   One carbon pool by folate mmu01100   Metabolic pathways mmu01232   Nucleotide metabolism mmu01523   Antifolate resistance mmu04981   Folate transport and metabolism Module mmu_M00938   Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP Brite KEGG Orthology (KO) [BR:mmu00001]  09100 Metabolism   09104 Nucleotide metabolism    00240 Pyrimidine metabolism     22171 (Tyms)   09108 Metabolism of cofactors and vitamins    00670 One carbon pool by folate     22171 (Tyms)  09150 Organismal Systems   09154 Digestive system    04981 Folate transport and metabolism     22171 (Tyms)  09160 Human Diseases   09176 Drug resistance: antineoplastic    01523 Antifolate resistance     22171 (Tyms) Enzymes [BR:mmu01000]  2. Transferases   2.1  Transferring one-carbon groups    2.1.1  Methyltransferases     2.1.1.45  thymidylate synthase      22171 (Tyms) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Thymidylat_synt Motif Other DBs NCBI-GeneID:  22171 NCBI-ProteinID:  NP_067263 MGI:  98878 Ensembl:  ENSMUSG00000025747 UniProt:  P07607 Q544L2 Structure PDBPDBj LinkDB All DBs Position 5:complement(30243544..30279261) Genome browser AA seq 307 aa AA seqDB search MLVVGSELQSDAQQLSAEAPRHGELQYLRQVEHILRCGFKKEDRTGTGTLSVFGMQARYS LRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVRIWDANGSRDFLDSLGFSAR QEGDLGPVYGFQWRHFGAEYKDMDSDYSGQGVDQLQKVIDTIKTNPDDRRIIMCAWNPKD LPLMALPPCHALCQFYVVNGELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHITGLQPG DFVHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVETIDDFKVEDFQIEGYNPHPT IKMEMAV NT seq 924 nt NT seq  +upstreamnt  +downstreamnt atgctggtggttggctccgagctgcagtccgatgctcagcagctgagcgcggaagcccca cggcatggagaactccagtacctgaggcaggtggagcacattttgcgctgcggcttcaag aaggaggaccgcacgggcactggcaccctgtcggtgttcggcatgcaggcacgatacagc ctgagagatgaatttcctctgctcacaaccaaacgagtgttctggaagggtgttttggag gagttgttgtggtttatcaagggatccacaaatgctaaagaattgtcctcaaagggagtg agaatctgggatgccaatggatcccgagattttctggacagcttgggattttctgcccga caggaaggggacctgggcccagtttatggtttccaatggaggcattttggagcagagtac aaagatatggattcagattactcgggacaaggagtagaccagctgcaaaaagtgattgac accatcaaaaccaaccctgatgacagaagaatcatcatgtgtgcctggaacccaaaagat cttcccctgatggcactgcctccttgccatgccctctgtcagttctatgtggtgaatggg gaactgtcttgccagctttaccagaggtcaggagatatgggtctgggcgtgcccttcaac attgccagctatgctctgctcacctacatgattgcacatatcacaggcctgcagccaggt gattttgtccacactttgggagatgcacatatttacctgaatcatatagagccgctgaaa attcagctacagcgagaaccaagacctttcccaaagctcaaaatccttcgaaaagttgag acaatcgatgatttcaaagttgaagactttcagattgaagggtataatccacatccaacg attaaaatggaaatggctgtttag

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