Mus musculus (house mouse): 22201
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Entry
22201 CDS
T01002
Symbol
Uba1, A1S9, Sbx, Ube-1, Ube1x
Name
(RefSeq) ubiquitin-like modifier activating enzyme 1
KO
K03178
ubiquitin-activating enzyme E1 [EC:
6.2.1.45
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04120
Ubiquitin mediated proteolysis
mmu05012
Parkinson disease
mmu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
22201 (Uba1)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
22201 (Uba1)
05022 Pathways of neurodegeneration - multiple diseases
22201 (Uba1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
mmu04121
]
22201 (Uba1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
22201 (Uba1)
Enzymes [BR:
mmu01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.45 E1 ubiquitin-activating enzyme
22201 (Uba1)
Ubiquitin system [BR:
mmu04121
]
Ubiquitin-activating enzymes (E1)
Ubiquitin activating enzyme
22201 (Uba1)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
22201 (Uba1)
Exosomal proteins of other body fluids (saliva and urine)
22201 (Uba1)
Exosomal proteins of colorectal cancer cells
22201 (Uba1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
UBA_E1_SCCH
ThiF
E1_UFD
E1_FCCH
E1_4HB
DUF7243
Motif
Other DBs
NCBI-GeneID:
22201
NCBI-ProteinID:
NP_001129557
MGI:
98890
Ensembl:
ENSMUSG00000001924
UniProt:
Q02053
B9EHN0
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:20524660..20549420
Genome browser
AA seq
1058 aa
AA seq
DB search
MSSSPLSKKRRVSGPDPKPGSNCSPAQSALSEVSSVPTNGMAKNGSEADIDESLYSRQLY
VLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSSQFYLRE
EDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSSFQVVVLTNSPLEAQLRVGEFCH
SRGIKLVVADTRGLFGQLFCDFGEEMVLTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARH
GFETGDFVSFSEVQGMIQLNGCQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKK
ISFKSLPASLVEPDFVMTDFAKYSRPAQLHIGFQALHQFCALHNQPPRPRNEEDATELVG
LAQAVNARSPPSVKQNSLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPI
MQWLYFDALECLPEDKEALTEEKCLPRQNRYDGQVAVFGSDFQEKLSKQKYFLVGAGAIG
CELLKNFAMIGLGCGEGGEVVVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN
PYIQVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNIDARMYMDRRCVYYRKPLLESGT
LGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPA
ENVNQYLTDSKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWGDCVTWACHHWHTQYCN
NIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNTLHLDYVMAAANLFAQTYGLTG
SQDRAAVASLLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLP
GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDISPADRHKSKLIAGKIIPAIATTTAA
VVGLVCLELYKVVQGHQQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEV
QGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVS
RVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR
NT seq
3177 nt
NT seq
+upstream
nt +downstream
nt
atgtccagctcgccgctgtccaagaaacgtcgcgtgtccgggcctgatccaaagccgggt
tctaactgctcccctgcacagtctgcgctgtccgaagtgtcctcagtgccaaccaacgga
atggcgaagaacggcagtgaagcagacatagacgagagcctttactcccggcagctgtac
gttttgggccatgaggcaatgaaaatgctccagacatccagcgtccttgtctcaggcttg
cggggcttgggtgtagaaattgctaagaacatcatccttggtggggtcaaggctgtcacc
ctacatgaccaaggaactacccagtgggctgatctctcctcccagttttaccttcgggag
gaggacattggtaaaaatcgagcggaggtatcccagccccgacttgctgaactcaacagc
tatgtacctgtcactgcctacactgggcctcttgtcgaggacttccttagtagcttccag
gtggtggtcctcaccaacagccccctggaagcccagctgcgagtgggggagttctgtcat
agccgtggtatcaagctagtggtggcagatacaagaggcctgtttgggcaacttttctgt
gattttggagaggaaatggtcctcacagattccaatggggagcagccactcagtgctatg
gtttcaatggtcaccaaggacaaccccggtgtggttacctgccttgatgaggcccgacat
ggctttgagactggtgacttcgtctcattctcagaagtacagggcatgatccaactcaat
ggatgtcagcccatggagatcaaagtgctgggtccttatacctttagtatctgtgacact
tccaacttctctgactacatccgtggaggcatcgtcagtcaggtcaaagtaccgaaaaag
attagttttaaatccttgccagcatcactggtagagcctgactttgtgatgactgacttt
gccaagtattctcgccctgcccaactgcacattggcttccaagctctgcaccaattctgt
gctctgcacaaccaaccacctcgaccacgaaatgaggaagatgcaacagagctggtgggc
ctggctcaggctgtaaacgctcggtccccaccttcagtaaaacagaacagcttggatgaa
gaccttattcggaagctagcttatgttgctgctggggacctggcacccataaatgctttc
attgggggccttgctgcccaggaagtcatgaaggcctgctctggaaagtttatgcccatc
atgcagtggttgtactttgatgctcttgaatgtctcccagaggacaaagaggctctgaca
gaggagaagtgcctcccacgtcagaaccgttacgatgggcaggtagctgtatttgggtca
gactttcaggagaagctgagcaagcaaaagtacttcctggtgggtgcaggggccattggc
tgtgaattgctcaagaactttgccatgattgggctgggttgtggagagggtggagaggtc
gtggtcacagacatggacaccattgagaaatcaaatctgaaccgacagtttctcttccgg
ccctgggatgtcacgaagttaaagtctgacacggccgctgcagctgtgcgccagatgaat
ccttacatccaggtgacaagccaccagaaccgtgtaggtcctgacactgagcgcatctat
gatgatgatttcttccaaaatttggatggtgtggccaatgctctggacaacatagatgcc
cgcatgtacatggatcgccgatgtgtgtactatcggaagccactgctagagtctggcaca
ctgggcacaaagggcaacgtgcaggtggtaatccccttcctgacagaatcctacagctct
agccaggatccaccagagaaatccatccccatttgtaccctgaaaaactttcccaatgcc
atcgaacacactcttcagtgggcccgggatgaatttgaaggccttttcaagcagccagca
gaaaatgttaatcagtacctcacagactccaaatttgtggagcggacattgcggctggct
ggtacccagccattggaggtgctggaggctgtgcagcgcagcctggtgttgcagcgacca
cagacttggggagactgtgtgacctgggcctgccaccactggcacacccagtactgtaac
aacatccggcaactgctgcacaactttcctcctgaccagctcaccagctcaggggcccct
ttctggtctggacccaaacgctgtccacacccacttacttttgatgttaacaatacattg
catctggattatgtgatggctgctgccaacctttttgcccagacctatgggttgactgga
tcccaagaccgagctgctgtggcctcactcctgcagtcagtacaagtcccagagttcacc
cccaagtctggtgtcaagattcatgtttctgaccaggagttgcagagtgccaatgcctct
gttgatgacagccgtcttgaggagctcaaagccacattgcccagcccagacaagttaccc
ggatttaagatgtaccccattgattttgagaaggatgatgacagcaatttccacatggat
ttcattgtggctgcatccaatcttcgggccgaaaactatgatatttcccctgcagaccga
cacaagagcaagctgattgcagggaagatcatcccagccattgccacaaccacagctgct
gtggttggccttgtgtgtctggagctctacaaggtagttcaagggcaccaacagctcgat
tcctacaaaaatggtttcctgaacttggccctgcccttctttgggttttctgaacctctt
gctgcacctcgtcaccagtactataatcaagagtggacattgtgggatcgctttgaagta
caagggctgcagcctaatggtgaggagatgaccctcaagcagttccttgattactttaag
acagagcacaaattggagatcaccatgctgtcccagggcgtgtccatgctctattctttc
ttcatgccagctgctaagctcaaggaacgattggatcagccgatgacagagattgtgagc
cgagtgtcaaagagaaagctgggccgccatgtgcgggcactggtgcttgagctgtgctgc
aacgatgaaagcggcgaggacgtcgaggtcccttatgtccgatataccattcgctga
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integrated database retrieval system
