Mus musculus (house mouse): 22201
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Entry
22201 CDS
T01002
Symbol
Uba1, A1S9, Sbx, Ube-1, Ube1x
Name
(RefSeq) ubiquitin-like modifier-activating enzyme 1
KO
K03178
ubiquitin-activating enzyme E1 [EC:
6.2.1.45
]
Organism
mmu
Mus musculus (house mouse)
Pathway
mmu04120
Ubiquitin mediated proteolysis
mmu05012
Parkinson disease
mmu05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
mmu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
22201 (Uba1)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
22201 (Uba1)
05022 Pathways of neurodegeneration - multiple diseases
22201 (Uba1)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:
mmu04121
]
22201 (Uba1)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:
mmu04147
]
22201 (Uba1)
Enzymes [BR:
mmu01000
]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.45 E1 ubiquitin-activating enzyme
22201 (Uba1)
Ubiquitin system [BR:
mmu04121
]
Ubiquitin-activating enzymes (E1)
Ubiquitin activating enzyme
22201 (Uba1)
Exosome [BR:
mmu04147
]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
22201 (Uba1)
Exosomal proteins of other body fluids (saliva and urine)
22201 (Uba1)
Exosomal proteins of colorectal cancer cells
22201 (Uba1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
UBA_E1_SCCH
ThiF
E1_UFD
E1_FCCH
E1_4HB
BilD_C
Motif
Other DBs
NCBI-GeneID:
22201
NCBI-ProteinID:
NP_001129557
MGI:
98890
Ensembl:
ENSMUSG00000001924
UniProt:
Q02053
B9EHN0
Structure
PDB
PDBj
LinkDB
All DBs
Position
X:20524660..20549420
Genome browser
AA seq
1058 aa
AA seq
DB search
MSSSPLSKKRRVSGPDPKPGSNCSPAQSALSEVSSVPTNGMAKNGSEADIDESLYSRQLY
VLGHEAMKMLQTSSVLVSGLRGLGVEIAKNIILGGVKAVTLHDQGTTQWADLSSQFYLRE
EDIGKNRAEVSQPRLAELNSYVPVTAYTGPLVEDFLSSFQVVVLTNSPLEAQLRVGEFCH
SRGIKLVVADTRGLFGQLFCDFGEEMVLTDSNGEQPLSAMVSMVTKDNPGVVTCLDEARH
GFETGDFVSFSEVQGMIQLNGCQPMEIKVLGPYTFSICDTSNFSDYIRGGIVSQVKVPKK
ISFKSLPASLVEPDFVMTDFAKYSRPAQLHIGFQALHQFCALHNQPPRPRNEEDATELVG
LAQAVNARSPPSVKQNSLDEDLIRKLAYVAAGDLAPINAFIGGLAAQEVMKACSGKFMPI
MQWLYFDALECLPEDKEALTEEKCLPRQNRYDGQVAVFGSDFQEKLSKQKYFLVGAGAIG
CELLKNFAMIGLGCGEGGEVVVTDMDTIEKSNLNRQFLFRPWDVTKLKSDTAAAAVRQMN
PYIQVTSHQNRVGPDTERIYDDDFFQNLDGVANALDNIDARMYMDRRCVYYRKPLLESGT
LGTKGNVQVVIPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTLQWARDEFEGLFKQPA
ENVNQYLTDSKFVERTLRLAGTQPLEVLEAVQRSLVLQRPQTWGDCVTWACHHWHTQYCN
NIRQLLHNFPPDQLTSSGAPFWSGPKRCPHPLTFDVNNTLHLDYVMAAANLFAQTYGLTG
SQDRAAVASLLQSVQVPEFTPKSGVKIHVSDQELQSANASVDDSRLEELKATLPSPDKLP
GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYDISPADRHKSKLIAGKIIPAIATTTAA
VVGLVCLELYKVVQGHQQLDSYKNGFLNLALPFFGFSEPLAAPRHQYYNQEWTLWDRFEV
QGLQPNGEEMTLKQFLDYFKTEHKLEITMLSQGVSMLYSFFMPAAKLKERLDQPMTEIVS
RVSKRKLGRHVRALVLELCCNDESGEDVEVPYVRYTIR
NT seq
3177 nt
NT seq
+upstream
nt +downstream
nt
atgtccagctcgccgctgtccaagaaacgtcgcgtgtccgggcctgatccaaagccgggt
tctaactgctcccctgcacagtctgcgctgtccgaagtgtcctcagtgccaaccaacgga
atggcgaagaacggcagtgaagcagacatagacgagagcctttactcccggcagctgtac
gttttgggccatgaggcaatgaaaatgctccagacatccagcgtccttgtctcaggcttg
cggggcttgggtgtagaaattgctaagaacatcatccttggtggggtcaaggctgtcacc
ctacatgaccaaggaactacccagtgggctgatctctcctcccagttttaccttcgggag
gaggacattggtaaaaatcgagcggaggtatcccagccccgacttgctgaactcaacagc
tatgtacctgtcactgcctacactgggcctcttgtcgaggacttccttagtagcttccag
gtggtggtcctcaccaacagccccctggaagcccagctgcgagtgggggagttctgtcat
agccgtggtatcaagctagtggtggcagatacaagaggcctgtttgggcaacttttctgt
gattttggagaggaaatggtcctcacagattccaatggggagcagccactcagtgctatg
gtttcaatggtcaccaaggacaaccccggtgtggttacctgccttgatgaggcccgacat
ggctttgagactggtgacttcgtctcattctcagaagtacagggcatgatccaactcaat
ggatgtcagcccatggagatcaaagtgctgggtccttatacctttagtatctgtgacact
tccaacttctctgactacatccgtggaggcatcgtcagtcaggtcaaagtaccgaaaaag
attagttttaaatccttgccagcatcactggtagagcctgactttgtgatgactgacttt
gccaagtattctcgccctgcccaactgcacattggcttccaagctctgcaccaattctgt
gctctgcacaaccaaccacctcgaccacgaaatgaggaagatgcaacagagctggtgggc
ctggctcaggctgtaaacgctcggtccccaccttcagtaaaacagaacagcttggatgaa
gaccttattcggaagctagcttatgttgctgctggggacctggcacccataaatgctttc
attgggggccttgctgcccaggaagtcatgaaggcctgctctggaaagtttatgcccatc
atgcagtggttgtactttgatgctcttgaatgtctcccagaggacaaagaggctctgaca
gaggagaagtgcctcccacgtcagaaccgttacgatgggcaggtagctgtatttgggtca
gactttcaggagaagctgagcaagcaaaagtacttcctggtgggtgcaggggccattggc
tgtgaattgctcaagaactttgccatgattgggctgggttgtggagagggtggagaggtc
gtggtcacagacatggacaccattgagaaatcaaatctgaaccgacagtttctcttccgg
ccctgggatgtcacgaagttaaagtctgacacggccgctgcagctgtgcgccagatgaat
ccttacatccaggtgacaagccaccagaaccgtgtaggtcctgacactgagcgcatctat
gatgatgatttcttccaaaatttggatggtgtggccaatgctctggacaacatagatgcc
cgcatgtacatggatcgccgatgtgtgtactatcggaagccactgctagagtctggcaca
ctgggcacaaagggcaacgtgcaggtggtaatccccttcctgacagaatcctacagctct
agccaggatccaccagagaaatccatccccatttgtaccctgaaaaactttcccaatgcc
atcgaacacactcttcagtgggcccgggatgaatttgaaggccttttcaagcagccagca
gaaaatgttaatcagtacctcacagactccaaatttgtggagcggacattgcggctggct
ggtacccagccattggaggtgctggaggctgtgcagcgcagcctggtgttgcagcgacca
cagacttggggagactgtgtgacctgggcctgccaccactggcacacccagtactgtaac
aacatccggcaactgctgcacaactttcctcctgaccagctcaccagctcaggggcccct
ttctggtctggacccaaacgctgtccacacccacttacttttgatgttaacaatacattg
catctggattatgtgatggctgctgccaacctttttgcccagacctatgggttgactgga
tcccaagaccgagctgctgtggcctcactcctgcagtcagtacaagtcccagagttcacc
cccaagtctggtgtcaagattcatgtttctgaccaggagttgcagagtgccaatgcctct
gttgatgacagccgtcttgaggagctcaaagccacattgcccagcccagacaagttaccc
ggatttaagatgtaccccattgattttgagaaggatgatgacagcaatttccacatggat
ttcattgtggctgcatccaatcttcgggccgaaaactatgatatttcccctgcagaccga
cacaagagcaagctgattgcagggaagatcatcccagccattgccacaaccacagctgct
gtggttggccttgtgtgtctggagctctacaaggtagttcaagggcaccaacagctcgat
tcctacaaaaatggtttcctgaacttggccctgcccttctttgggttttctgaacctctt
gctgcacctcgtcaccagtactataatcaagagtggacattgtgggatcgctttgaagta
caagggctgcagcctaatggtgaggagatgaccctcaagcagttccttgattactttaag
acagagcacaaattggagatcaccatgctgtcccagggcgtgtccatgctctattctttc
ttcatgccagctgctaagctcaaggaacgattggatcagccgatgacagagattgtgagc
cgagtgtcaaagagaaagctgggccgccatgtgcgggcactggtgcttgagctgtgctgc
aacgatgaaagcggcgaggacgtcgaggtcccttatgtccgatataccattcgctga
DBGET
integrated database retrieval system
