| Entry |
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| Symbol |
Uba1y, A1s9Y-1, Sby, Ube-2, Ube1ay, Ube1y, Ube1y-1, Ube1y1
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| Name |
(RefSeq) ubiquitin-like modifier-activating enzyme 1 Y
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| KO |
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| Organism |
mmu Mus musculus (house mouse)
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| Pathway |
| mmu05022 | Pathways of neurodegeneration - multiple diseases |
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| Brite |
KEGG Orthology (KO) [BR:mmu00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
22202 (Uba1y)
09160 Human Diseases
09164 Neurodegenerative disease
05012 Parkinson disease
22202 (Uba1y)
05022 Pathways of neurodegeneration - multiple diseases
22202 (Uba1y)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system [BR:mmu04121]
22202 (Uba1y)
09183 Protein families: signaling and cellular processes
04147 Exosome [BR:mmu04147]
22202 (Uba1y)
Enzymes [BR:mmu01000]
6. Ligases
6.2 Forming carbon-sulfur bonds
6.2.1 Acid-thiol ligases
6.2.1.45 E1 ubiquitin-activating enzyme
22202 (Uba1y)
Ubiquitin system [BR:mmu04121]
Ubiquitin-activating enzymes (E1)
Ubiquitin activating enzyme
22202 (Uba1y)
Exosome [BR:mmu04147]
Exosomal proteins
Exosomal proteins of haemopoietic cells (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
22202 (Uba1y)
Exosomal proteins of other body fluids (saliva and urine)
22202 (Uba1y)
Exosomal proteins of colorectal cancer cells
22202 (Uba1y)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
Y:818612..843684
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| AA seq |
1058 aa
MSSSVLSKKRKVSGPDSSLDSSWSPTYSVMFGVPPGPTNEMSKNKEMDIDESLYSRQLYV
LGHEAMKHLQASSVLISGLQGLGVEIAKNIILGGVKAVTLHDQGIAQWADLSSQFCLREE
DIGKNRAEISQPRLAELNSYVPVFAYTGPLIEEFLSGFQVVVLTNTPLEYQLQVGEFCHS
HGIKLVVADTRGLVGQLFCDFGEEMILTDSNGEQPLSAMVSMITKENPGIVTCLEDSRHG
FESGDFISFTEVQGMSELNGIGPIEIKVLGPYTFSICDTSSFSEYIRGGIVSQVKVPRKI
NFKPLLASLAEPEFVVTDFAKCCHPAQLHIGFQALHQFCTQHSRPPRPHNEEDAEELVTL
AQSVNAQALPAVQQDCLDIDLIRKLAYVAAGDLAPMNAFFGGLAAQEVMKACSGKFMPIR
QWLYFDALECLPEHRVAFMEDKCLPHQNRYDGQVAVFGSDLQEKLGKQKYFLVGAGAIGC
ELLKNFAMIGLGCGEDGEITVTDMDTIEKSNLNRQFLFRPWDITKLKSETAAAAVRDINP
HIRIFSHQNRVGPETEHVYDDDFFQKLDGVANALDNVDARLYVDRRCVYYRKPLLESGTL
GTKGNVQVVVPFLTESYSSSQDPPEKSIPICTLKNFPNAIEHTVQWARDEFEGLFKQSAE
NVNQYLTDPKFMERTLQLAGTQPLEVLEAIHCSLVLQRPQTWADCVTWAYQHWHTQYSHN
IQQLLHNFPPAQLTSSGALFWSGPKRCPHPLTFDINNPLHLDYVMAAANLFAQTYGLGGS
QDCAVVAKLLQSLPVPKFAPKSGIRIHVSEQELQSTSATTIDDSHLEELKTALPTPDKLL
GFKMYPIDFEKDDDSNFHMDFIVAASNLRAENYGISPADRHKSKLIAGKIIPAIATTTSA
IVGLVCLELYKVVQGHQQLESYKNSFINLALPLFSFSAPLAPECHQYYDQEWTLWDRFDV
QGLQPSGEEMTLKQFLDYFKTEHKLEVIMLSQGVSMLYSVFMPASKLKERLDQPMTEIVS
CVSKQKLGHHVKSLVFELCCNSDSGDDIEVPYVRYIIR |
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| NT seq |
3177 nt +upstreamnt +downstreamnt
atgtccagctcagtcctgtccaagaaacgcaaagtgtctggacctgactctagtctggat
tctagttggtctcctacctattctgtgatgtttggcgtgcccccagggccaaccaacgaa
atgtcaaaaaataaggaaatggacatagatgaaagcctttactcccgccagctgtatgta
ctcggccatgaggcaatgaagcatctccaggcttccagtgtactgatatcaggcctgcag
ggtctgggtgtggaaattgccaagaatatcatccttggtggggtcaaggctgtcactctc
catgatcagggcattgcccagtgggctgatctgtcttcccagttctgcctacgtgaggaa
gatattggtaaaaaccgagctgagatatcccaaccacgccttgctgaactcaacagttac
gttcctgtgtttgcctacactggacctctaattgaggagttccttagtggttttcaggta
gtggttcttaccaacactcctttggaatatcagctgcaggtgggtgaattctgccatagc
cacggaatcaagctggtagtagcagacactcggggcctagttggacaactcttctgtgac
tttggagaggaaatgattctcactgattcaaatggagaacagccactcagtgccatggtt
tcaatgatcactaaggagaatccagggattgtcacctgcctggaggactcccggcatgga
tttgaaagtggtgactttatctctttcacagaagttcagggcatgagtgaactcaatggc
attggtcccatagagatcaaagttctgggtccctatacctttagtatctgtgatacctcc
agcttctctgagtacatccgtggaggcattgtcagtcaagtgaaagtacctcggaagatc
aattttaaacccctacttgcctcgctggcagagccagagtttgtggtcacagattttgct
aagtgctgtcatcctgctcagctccacattggcttccaggccctgcatcagttctgtact
cagcacagcaggcctcctcggccccataatgaggaggatgctgaggaattggtgacctta
gcccaatctgtgaatgctcaagctttgccagcagttcagcaggattgcctggacatcgac
cttatccggaagttggcctatgtagcagctggggacctggcacccatgaatgcctttttt
ggtggtttggctgcccaggaggtcatgaaggcttgttctggaaagtttatgcccattagg
cagtggctgtactttgatgcccttgaatgtctcccagagcacagagtggccttcatggaa
gataagtgcctgccacaccagaaccgttatgatgggcaagtggctgtatttggatcagac
ctacaagagaagcttggcaagcagaaatacttcctggtaggtgcaggtgccattggctgt
gagctgctcaagaactttgccatgattggcctcggctgtggggaggatggagaaatcaca
gttacagacatggacaccattgagaagtcaaacctgaacaggcagtttctcttccgtccc
tgggacatcacaaaattaaagtctgagactgctgctgcagcagtgcgtgacataaatcca
cacatcaggatattcagccaccagaatcgagtaggcccagagacagaacacgtctatgat
gatgacttcttccaaaagctggatggtgtggccaatgccctagacaatgtggatgctcga
ttatacgtggaccgccgttgtgtttactatcgtaagcctctgctggaatcaggcacgctg
ggcaccaagggcaacgtgcaggtggttgttcccttcttgacagaatcttacagctcaagc
caggacccacctgagaaatccatccccatctgcacactgaagaacttccctaatgccatt
gagcacaccgtgcagtgggctcgggatgagtttgaagggctcttcaagcagtcagctgaa
aatgttaaccaatacctcacggaccccaagttcatggagcggacactgcagctagccggc
acccagcctttggaagtactggaggccatacactgcagcctggtcctgcagaggccacag
acttgggccgactgtgtgacttgggcctaccagcactggcacacccagtattctcacaac
atccagcagttgctgcacaacttccctccagcacagcttacgagctctggagcacttttt
tggtcaggaccaaaacgctgtccacatcctctcacctttgacataaacaatcccctgcat
ctggattatgtgatggctgctgccaacctgtttgctcagacatacggactaggagggtcc
caggactgtgctgtggtggccaaactcctgcagtctctgccagtccccaagtttgctccc
aagtctggcatcaggatccatgtttctgagcaggagctgcagagtaccagtgccaccacc
attgatgacagccacctggaggaactcaagactgcacttcctactccagacaagctgctt
ggattcaagatgtaccccattgactttgagaaggatgacgacagcaactttcacatggat
ttcattgtggcagcatccaacctccgagcagaaaactatggcatttccccagcagaccgg
cataagagcaaactgattgcaggcaagatcatcccagccattgcaaccaccacatctgct
atagttggccttgtgtgtctggagctgtacaaggtggttcagggccaccaacaactggag
tcttataaaaacagttttatcaacttggctctgcctttgtttagcttttctgcacctctg
gctccagagtgtcatcagtactatgatcaagagtggacactgtgggatcgctttgatgtg
caaggactgcaacctagcggtgaggagatgaccttgaagcagtttctagactactttaag
acagagcacaagctggaagtcatcatgctgtcccagggtgtgtccatgctctattctgtc
tttatgccagccagcaagctcaaagaacggttggatcagccgatgacagagattgtgagc
tgtgtgtcaaagcaaaaactgggccatcatgtgaagtcacttgtgtttgagctgtgctgc
aacagtgacagtggagacgacatagaggttccttatgtacgatacatcatccgctga |
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